• Title/Summary/Keyword: 디지털 치료제

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The Healing Properties of English Poetry In a Digital Age (디지털 시대 영시의 치유적 속성)

  • Kim, Kyoung-Soon
    • Journal of Digital Convergence
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    • v.13 no.10
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    • pp.437-444
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    • 2015
  • In this age of digital technology, we often experience overwhelming and inescapable feelings of weakness, vulnerability, loneliness and fear that propel us into a state of gloom or frustration. Poetry can also serve as a therapeutic medium for overcoming them because it provides unique opportunities for self-discovery and is a catalyst for healing and self-integration. This study examines the healing properties in English poetry. First, Poetry has expressed innermost feelings, which can serve as a catharsis the emotional release. Therefore it can nurture and strengthen the human capacity. Poetic language heals our soul and mind. Rhythm which comes in many forms and poetic form also are important components of the therapeutic value of poetry. So we can say English poetry can be used as a therapeutic means for healing and personal growth.

An Empirical Study on the Efficacy of Mindfulness Activation Tools for Psychological Stability Support: A Focus on Voluntary Groups (심리 안정을 지원하는 현존의식 활성화 도구의 효용성 연구 - 자발적 포커스그룹 중심)

  • Joong Ho Lee
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.4
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    • pp.383-388
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    • 2024
  • This study conducted voluntary focus group user observations to empirically validate the efficacy of the self-developed psychological support mobile application, "Mindful Now". The app is structured as an interactive game format, enabling individuals to activate self-awareness of mindfulness states anytime, anywhere. It consists of a 3-step process of sensory/emotional/consciousness awareness, facilitating the expression of non-judgmental awareness. To demonstrate the effectiveness of this mindful activation in enhancing psychological well-being such as happiness and stress reduction, voluntary mindfulness mobile app usage was tracked among 49 university students. The results revealed significant improvements, with a 14.4% increase in SWLS happiness index and a 17.1% decrease in PSS-10 stress levels among 12 users who used the app continuously for over 60 days to practice mindfulness awareness. Particularly, higher app engagement was observed among students who initially reported relatively lower indices before using the app. The utilization of mobile apps that promote mindful activation aligns with various therapeutic paradigms based on mindfulness and meditation, contributing to advancements in digital therapeutic interventions for psychological support.

Suppressive effects of Th2 cytokines expression and the signal transduction mechanism in MC/9 mast cells by flavonol derived from Ginkgo biloba leaves (비만세포에서 은행잎 플라보놀에 의한 Th2 Cytokine 발현 및 신호전달 억제 기전 효과)

  • Kwon, Hae-Young;Chung, Kyu-Jin;Cheong, Kwang-Jo
    • Journal of Digital Convergence
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    • v.13 no.8
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    • pp.503-514
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    • 2015
  • The effects of Flavonol contents from Ginkgo biloba leaf on anti-atopy activity have not rarely been verified. This study is to investigate the effects of flavonol on Th2 cytokine production in MC/9 mast cells. For this, flavonol was analyzed by ELISA and Real-time PCR. Analysis results showed that flavonol significantly suppressed production of Th2 cytokines(IL-13, MIP-1a) in a dose dependent manner. The mRNA expression of IL-4, IL-5, IL-13, TNF-a were effectively restrained by Flavonol at the concentration 25,50,$100{\mu}g/m{\ell}$. And decrease of expression of NFAT-1, c-jun protein was confirmed by western blot analysis. These results indicate that flavonol has effects of decreasing the Th2 cytokine production in the MC/9 mast cell causing inhibition of transcription factors such as NFAT-1, c-jun. Thus, we would like to brief that flavonol may have the applicability as therapeutic agent for atopic dermatitis.

Anti-asthmatic activities of Cypress oil in a mouse model of allergic asthma (마우스 모델을 이용한 사이프러스 오일의 알러지성 천식 억제 효과)

  • Sueng, Yun-Cheal;Chung, Kyu-Jin;Cheong, Kwang-Jo
    • Journal of Digital Convergence
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    • v.13 no.1
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    • pp.341-351
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    • 2015
  • This study was aimed to evaluate the effects of Cypress oil(CS) on anti-asthmatic activities in a mouse model of allergic asthma. Using an Ovalbumin-induced allergic asthma mouse model, 0.3% of CS was administered to experimental group using a nebulizer for 3 weeks on a basis of 3 times per week and 30min each time. The degree of airway hypersensitivity, the number of eosinophil in white blood cells, the number of immune cells and the change of cytokine in lung tissue were evaluated. The degree of airway hypersensitivity, the number of eosinophil, IL-5 and IL-13 levels in lung tissue, IgE in serum, the number of CCR3, CD3, CD4 cells were significantly decreased in experimental group treated with CS. These results suggested that CS may have a positive effects on Th2 cytokine and eosinophils which are major factors of asthma responses. Therefore CS might be of therapeutic value in treating asthma.

Suppressing Effects of Ethanol Extract from Dioscoreae Rhizoma on atope Dermatitis (부채마 에탄올 추출물의 아토피 피부염 억제 효과)

  • Do, Young-Bog;Song, Young-Soon
    • Journal of Digital Convergence
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    • v.17 no.8
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    • pp.257-264
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    • 2019
  • This study was conducted to investigate the effect of 70% ethanol extract (DR) on the mast cell-mediated allergic contact dermatitis induced by dinitrofluorobenzene in BALB / c mice, which affects the cell activity by antigen in RBL-2H3 mast cells Respectively. The ethanol extracts of RBL-2H3 cells activated by DNP-HSA and anti-DNP IgE antibodies inhibited the secretion of ${\beta}$-hexosaminidase, histamine, and IL-4 and $TNF-{\alpha}$ Production was suppressed. In the DNFB-induced contact allergic dermatitis animal model, treatment with ethanol extract reduced ear swelling and inhibited serum histamine and IL-4 secretion, and DR treatment effectively prevented mast cell infiltration in dermatitis-induced areas. As a result, the ethanol extract may be used as a therapeutic agent for mast cell-mediated allergic diseases such as atopic dermatitis.

Effect of Broccoli Extract on Inhibition of Cancer Cell Proliferation (브로콜리 추출물의 암세포 증식 억제에 미치는 효과)

  • Jeong-Sook Park
    • Journal of Digital Policy
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    • v.2 no.1
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    • pp.31-35
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    • 2023
  • This study was conducted to examine the effect of Broccoli Extract on the proliferation inhibition of human-derived cancer cells and the degree of inhibition. The three cell lines used in the experiment were respiratory system lung cancer cells A549, digestive system liver cancer cells SNU-182 and biliary tract cancer SNU-1196. All cancer cells were derived from the human body, and the CCK-8 method was used to measure the degree of inhibition of cancer cell proliferation. As a result of examining the effect on Broccoli Extract 10ug/mL, 100ug/mL, 1000ug/mL, Broccoli Extract inhibited proliferation in a concentration-dependent manner in most cancer cells, In particular, lung cancer cell A549 and liver cancer cell SNU-182 showed significant proliferation inhibition at 1000ug/mL.As a result, it can be seen that broccoli extract provides potential as a cancer preventive and therapeutic agent for tumor suppression mechanisms proven through cell experiments.

Disease Prediction of Depression and Heart Trouble using Data Mining Techniques and Factor Analysis (데이터마이닝 기법 및 요인분석을 이용한우울증 및 심장병 질환 예측)

  • Yousik Hong;Hyunsook Lee;Sang-Suk Lee
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.23 no.4
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    • pp.127-135
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    • 2023
  • Nowadays, the number of patients committing suicide due to depression and stress is rapidly increasing. In addition, if stress and depression last for a long time, they are dangerous factors that can cause heart disease, brain disease, and high blood pressure. However, no matter how modern medicine has developed, it is a very difficult situation for patients with depression and heart disease without special drugs or treatments. Therefore, in many countries around the world, studies are being actively conducted to determine patients at risk of depression and patients at risk of suicide at an early stage using electrocardiogram, oxygen saturation, and brain wave analysis functions. In this paper, in order to analyze these problems, a computer simulation was performed to determine heart disease risk patients by establishing heart disease hypothesis data. In particular, in order to improve the predictive rate of heart disease by more than 10%, a simulation using fuzzy inference was performed.

Effect of digital therapies on balance and gait in children with cerebral palsy: A systematic review (디지털 치료제가 뇌성마비 아동의 균형 및 보행에 미치는 효과: 체계적 고찰)

  • Jung-Hyun Kim
    • Journal of Korean Physical Therapy Science
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    • v.30 no.4
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    • pp.92-110
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    • 2023
  • Background: Digital therapeutics are software medical devices that provide evidence-based treatments to prevent, manage, and treat disease. Digital therapies have recently been shown to be effective in motivating children with cerebral palsy as a tool in neuropsychological therapy. Digital therapies improve postural control, balance and gait in children with cerebral palsy. Therefore, this study aims to investigate the effects of digital therapies on balance and gait in children with cerebral palsy and to provide guidelines for prescribing digital therapies for children with cerebral palsy. Design: A Systematic Review Methods: This study searched for English-language articles published in medical journals from January 2000 to July 2023 using PubMed and MEDLINE based on the year of initiation of the digital therapy. The search terms used in the study were 'digital technology' OR 'digital therapeutic' OR 'mobile application' OR 'mobile health' OR 'virtual reality' OR 'game' AND 'cerebral palsy', 'balance' 'gait' as the main keywords. The final article was assigned an evidence level and a Physiotherapy Evidence Database (PEDro) score to assess the quality of clinical trials studies. Results: The digital therapies applied to improve balance and gait in children with cerebral palsy are game-based virtual reality training and the Nintendo Wii Fit program. Both digital therapy interventions had a significant effect on improving balance in children with cerebral palsy, and virtual reality training significantly improved balance and gait. However, there were no significant improvements in balance and gait within two weeks of treatment, regardless of the type of digital intervention. Conclusion: The study suggests that this data will be important in building the evidence base for the effectiveness of digital therapies on balance and gait in children with cerebral palsy and in advancing clinical protocols.

Dissemination of CTX-M Type Extended-Spectrum β-Lactamases Among Klebsiella pneumoniae Clinical isolates in Chungcheong Province (충청지역의 임상검체에서 분리된 폐렴막대균에 CTX-M형 Extended-Spectrum β-lactamases 확산)

  • Sung, Ji-Youn
    • Journal of Digital Convergence
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    • v.14 no.10
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    • pp.349-354
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    • 2016
  • The emergence and dissemination of extended-spectrum ${\beta}$-lactamse (ESBL) producing Klebsiella pneumoniae isolates make it more difficult to treatment of bacterial infections. In our study, we detected ESBL genes and investigated antimicrobial susceptibility of K. pneumoniae isolates in Chungcheong province. In addition, clonality among the isolates was analyzed by repetitive element sequence (REP)-PCR. Twenty-one of 102 K. pneumoniae isolates produced CTX-M-14 and/or CTX-M-15 and showed high level (over 70%) resistance to third cephalosporins. CTX-M type ESBL producing K. pneumoniae strains isolated in our study showed diverse clonality and some of the isolates have been disseminated in the community. Enhancing infection control will be needed to prevent dissemination of the K. pneumoniae isolates. In addition, for more effective control of resistant bacteria it is considered necessary to monitor the database constructed through convergence of biological investigation and statistical analysis of antimicrobial resistance genes.

A Study of the Digital Healthcare Industry in the Fourth Industrial Revolution (4차 산업혁명시대의 디지털 헬스케어 산업에 대한 연구)

  • Kim, Ki-Bong;Han, Kun-Hee
    • Journal of Convergence for Information Technology
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    • v.10 no.3
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    • pp.7-15
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    • 2020
  • As the paradigm shifts from treatment and provider-centered healthcare to prevention and consumer-centered healthcare, the integration of ICT convergence technology is calling for an era of digital healthcare industry revival in the Fourth Industrial Revolution. It is possible to provide individual customized medical services utilizing various medical data, and it is possible to provide various medical services that transcend time and space through integration with other industries. Such digital healthcare includes health, nutrition, exercise, and patient care, while the digital healthcare industry includes healthcare and IT related to medical devices, medical information systems, and healthcare platforms that can provide personal health and medical information. Due to the social demands of the aging and the increase of chronic diseases, digital healthcare is considered as an important policy in the fourth industrial revolution in Korea. In order for the digital healthcare industry to contribute to the prolongation of human life and the improvement of quality of life, it is urgent to develop related infrastructures, legal institutions, and prepare policies. In addition, it is important to activate convergent education to foster talents who will lead the digital healthcare industry. The purpose of this study was to examine the trends of the digital healthcare industry in the era of the fourth industrial revolution and the direction of government R & D policies, and to derive directions and suggestions for future development.