• Title/Summary/Keyword: 디지털병리

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A Rare Case of Tracheal Leiomyoma: Role of Digital Tomosynthesis in Diagnosis and Treatment (기관 내 평활근종의 드문 증례: 진단과 치료에서의 디지털 단층촬영술의 역할)

  • Soo Won Nam;Yeon Joo Jeong;Geewon Lee;Ji Won Lee;Jung Seop Eom;Chang Hun Lee;So Min Park
    • Journal of the Korean Society of Radiology
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    • v.81 no.1
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    • pp.225-230
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    • 2020
  • Tracheal leiomyoma is a rare benign tumor, which is composed of transformed cells of mesenchymal origin. We describe a case in which digital tomosynthesis was useful to evaluate a tracheal tumor that was overlooked on initial chest radiographs.

A Study on Automatic Classification System of Red Blood Cell for Pathological Diagnosis in Blood Digitial Image (혈액영상에서 병리진단을 위한 적혈구 세포의 자동분류에 관한 연구)

  • 김경수;김동현
    • Journal of the Korea Society of Computer and Information
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    • v.4 no.1
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    • pp.47-53
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    • 1999
  • In medical field, the computer has been used in the automatic processing of data derived in hospital. the automation of diagonal devices, and processing of medical digital images. In this paper, we classify red blood cell into 16 class including normal cell to the automation of blood analysis to diagnose disease. First, using UNL Fourier and invariant moment algorithm, we extract features of red blood cell from blood cell image and then construct multi-layer backpropagation neural network to recognize. We proof that the system can give support to blood analyzer through blood sample analysis of 10 patients.

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Mechanical Amusement Culture Phenomenon and the Context of Pre-Game Period in 1960s (1960년대 기계오락문화현상과 전(前)게임기의 맥락)

  • Jeon, Gyongran
    • Journal of Korea Game Society
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    • v.15 no.4
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    • pp.111-120
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    • 2015
  • The purpose of this study is to understand the sociocultural context of the pre-game period, and how the context influenced on the identity formation of games. Games did not develop with the fixed and stable identities. Instead, games is the outcome which is conceived in the history of articulation of various discourses, technologies and social factors. The mechanical amusement devices was consumed for the urban entertainment, and made a strained relations with the society for the speculative and pathological characteristics. The mechanical amusement has extended to the electronic games in 1970s, and reached the present digital game culture.

A study on classification of tongue coating using multi-dimensional color vectors (다차원 컬러벡터를 이용한 설태 분류 - 백태, 황태)

  • Lee, J.;Choi, E.J.;Ryu, H.H.;Lee, H.J.;Lee, Y.J.;Kim, J.Y.
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.1900-1901
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    • 2007
  • 한의학에서 혀는 인체 내 생리, 병리적 변화를 반영하여 진단에 있어 중요한 지표자료로 사용하고 있다. 하지만 설진은 진단환경에 의한 영향을 많이 받게 되어 객관적이고 정량화된 결과를 얻기 힘들며, 그로 인해 한의사의 진단에 대한 신뢰성도 낮아 널리 활용되지 못하고 있다. 이를 해결하기 위해 본 연구에서는 제한된 측정환경을 제공하는 디지털 설진 시스템을 통해 한의사로부터 황태라 진단받은 48명과 백태라 진단받은 14명의 설 영상을 획득하고, 설태의 컬러벡터값을 구하여 백태와 황태를 구분하는데 유의한 변수를 도출하였으며, 이를 이용하여 한의사의 설태 진단과 일치율이 높은 판별함수를 도출하였다. 이와같은 연구방법은 백태, 황태 뿐 아니라 회태나 흑태 또는 후태나 박태를 구분하는 데에도 유용하게 쓰일 수 있을 것이며 앞으로 한의사의 설진과정을 객관화, 과학화하는 과정에 기여할 수 있을 것이다.

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Predicting Acculturation for Chinese International Students in Korea: The Role of Social Support through SNS (SNS 이용 동기와 사회적 지지가 문화적응에 미치는 영향 - 국내 거주 중국인 유학생의 문화적응을 중심으로)

  • Moon, Shin-Il;Jia, Liao;Lee, Hyunjoo;Kim, Kitae
    • The Journal of the Korea Contents Association
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    • v.21 no.1
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    • pp.722-732
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    • 2021
  • A recent rapid growth in the number of Chinese international students in Korea has generated interest in the key factors to affect their acculturation in domestic culture. In accordance with the growing interest, the present study aims to empirically test and analyze the effects of demographics (gender, age, the length of stay, the length of Korean language education and the level of Korean language skills), SNS use patterns (personal network sizes and hours of use for Korean and Chinese SNS, and motivations of Korean or Chinese SNS uses), and social support through Korean and Chinese SNS on acculturation for Chinese international students in Korea. A total of 322 Chinese international students in Korea participated in the online survey. Results showed that use of Chinese SNS for entertainment had an negative impact on the acculturation, while the use of Korean SNS had an overall positive impact. Finally, this study suggests that the practitioners regarding the issue of acculturation for international students in Korea should focus more on specific guidelines to help their appropriate SNS uses rather than on to prevent their SNS addiction problems.

Inhibitory Effects of Ethanol Extract of Rhodiola Sacra on Endoplasmic Reticulum Stress in Neuro-2A Cells (설치류 Neuro-2A 신경세포에서 홍경천 에탄올 추출물의 소포체 스트레스 억제효과)

  • Jo, Nam-Eun;Song, Young-soon
    • Journal of Digital Convergence
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    • v.17 no.8
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    • pp.265-270
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    • 2019
  • Growing evidence suggests that mediating apoptotic cell death of ER stress plays an important role in pathological development of neurodegenerative diseases including Alzheimer's disease. The ethanol extract of Rodiola sacra (ERS) investigates whether ER stress protects neuroinvasive neuro-2A cells from homocysteine (Hcy) cell death and ER stress. In neuronal cells, Hcy markedly decreased the viability of the cells and induced the death of Annexin V-positive cells as confirmed by MTT assay. The Hcy cell viability and apoptotic loss pretreated with ERS were attenuated, and Hcy showed stress in the expression of C / EBP homologous protein, 78-kDa glucose regulatory protein and the junction of X-box binding protein-1 (xbp1) mRNA. ESR decreased Hcy-induced mRNA binding, GRP78 and CHOP cells induced Hcy-induced ER stress and apoptosis, and Western blotting revealed expression of heme oxygenase-1 and HO-1 enzyme activity Inhibition is indicative of therapeutic value for neurodegenerative diseases such as decreased cell death by hemin.

Molecular epidemiologic trends of norovirus and rotavirus infection and relation with climate factors: Cheonan, Korea, 2010-2019 (노로바이러스 및 로타바이러스 감염의 역학 및 기후요인과의 관계: 천안시, 2010-2019)

  • Oh, Eun Ju;Kim, Jang Mook;Kim, Jae Kyung
    • Journal of Digital Convergence
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    • v.18 no.12
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    • pp.425-434
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    • 2020
  • Background: Viral infection outbreaks are emerging public health concerns. They often exhibit seasonal patterns that could be predicted by the application of big data and bioinformatic analyses. Purpose: The purpose of this study was to identify trends in diarrhea-causing viruses such as rotavirus (Gr.A), norovirus G-I, and norovirus G-II in Cheonan, Korea. The identified related factors of diarrhea-causing viruses may be used to predict their trend and prevent their infections. Method: A retrospective analysis of 4,009 fecal samples from June 2010 to December 2019 was carried out at Dankook University Hospital in Cheonan. Reverse transcription-PCR (RT-PCR) was employed to identify virus strains. Information about seasonal patterns of infection was extracted and compared with local weather data. Results: Out of the 4,009 fecal samples tested using multiplex RT-PCR (mRT-PCR), 985 were positive for infection with Gr.A, G-I, and G-II. Out of these 985 cases, 95.3% (n = 939) were under 10 years of age. Gr.A, G-I, and G-II showed high infection rates in patients under 10 years of age. Student's t-test showed a significant correlation between the detection rate of Gr.A and the relative humidity. The detection rate of G-II significantly correlated with wind-chill temperature. Conclusion: Climate factors differentially modulate rotavirus and norovirus infection patterns. These observations provide novel insights into the seasonal impact on the pathogenesis of Gr.A, G-I, and G-II.

A Study on A Tablet-PC Based Application Design For Self-examination of Dementia (치매 자가 진단을 위한 태블릿 PC용 어플리케이션 설계 연구)

  • Ryu, Neung Hwa;Park, Seung Ho
    • Design Convergence Study
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    • v.13 no.2
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    • pp.143-164
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    • 2014
  • In this study, we suggest a tablet-PC based application as an instrument for self-examination of dementia and aim to evaluate its usability for the practical use. The tool for the self-diagnosis of dementia is testing a person's sentence comprehension, which is investigated by the accuracy of a sentence-picture matching task, and the result of the test can differentiate individuals with dementia of Alzheimer's type from normal aging population. According to its use for diagnosis of dementia, we developed a new version of sentence-picture matching task by a cooperative study with NABLE(Neurogenic communication And Brain Lab at Ewha) and applied to the application as a main function. Targeting the New Silver who are preliminary aged people in Korea, this application can provide them with three values: 'self-', 'easy', and 'simple'. When using this application, users can gain these values by an instruction manual with the recorded guide voice, easy-to-use functions and the simplified menu structure of it. After prototyping, we conducted the usability test and it was proved as a result that the New Silver users can easily operate the application by themselves.

Basic Research for the Recognition Algorithm of Tongue Coatings for Implementing a Digital Automatic Diagnosis System (디지털 자동 설진 시스템 구축을 위한 설태 인식 알고리즘 기초 연구)

  • Kim, Keun-Ho;Ryu, Hyun-Hee;Kim, Jong-Yeol
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.1
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    • pp.97-103
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    • 2009
  • The status and the property of a tongue are the important indicators to diagnose one's health like physiological and clinicopathological changes of inner organs. However, the tongue diagnosis is affected by examination circumstances like a light source, patient's posture, and doctor's condition. To develop an automatic tongue diagnosis system for an objective and standardized diagnosis, classifying tongue coating is inevitable but difficult since the features like color and texture of the tongue coatings and substance have little difference, especially in the neighborhood on the tongue surface. The proposed method has two procedures; the first is to acquire the color table to classify tongue coatings and substance by automatically separating coating regions marked by oriental medical doctors, decomposing the color components of the region into hue, saturation and brightness and obtaining the 2nd order discriminant with statistical data of hue and saturation corresponding to each kind of tongue coatings, and the other is to apply the tongue region in an input image to the color table, resulting in separating the regions of tongue coatings and classifying them automatically. As a result, kinds of tongue coatings and substance were segmented from a face image corresponding to regions marked by oriental medical doctors and the color table for classification took hue and saturation values as inputs and produced the classification of the values into white coating, yellow coating and substance in a digital tongue diagnosis system. The coating regions classified by the proposed method were almost the same to the marked regions. The exactness of classification was 83%, which is the degree of correspondence between what Oriental medical doctors diagnosed and what the proposed method classified. Since the classified regions provide effective information, the proposed method can be used to make an objective and standardized diagnosis and applied to an ubiquitous healthcare system. Therefore, the method will be able to be widely used in Oriental medicine.

The effect of temperature and breeding density of piggery on the collection of oral fluid in Korea (국내 양돈장의 사육 온도와 밀사율이 구강액 채취율에 미치는 영향)

  • Byeon, Hyeon Seop;Kim, Mihwa;Kwon, Sungae;Han, Mina;Han, Sung Tae;Jang, Rae Hoon;Chung, Yun-Soo;Kim, Seokhyun;Jeon, Bo-Young
    • Korean Journal of Veterinary Service
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    • v.44 no.4
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    • pp.217-225
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    • 2021
  • We investigated the effect of temperature and stock density on the collection efficiency of oral fluid in the pig farm in Korea. Three pig farms with similar breeding environmental conditions were selected and four pens of each farm (total 12 pens) were tested for the collection efficiency of oral fluid from pigs. Collection rate was considered as significant when oral fluid was collected from 70% of pigs within a pen. In the case of growing pigs, when internal temperature of pig barn increased by one designated degree (5℃), the oral fluid collection rate significantly decreased by 24.7% (P<0.05). The collection rate of oral fluid also decreased by 7.1% (P<0.05) as the density rate increase by one designated degree (12.5%). It was estimated that the collection efficiency of oral fluid decreased when the internal temperature of pig barn was 30℃ or higher, or barn density is higher 25% or high. On the other hand, in the case of stall-housing sows, unlike growing pigs, there was no significant differences according to the temperature, so oral fluid collection was considered to be efficient even in hot season.