• Journal of the Society of Cosmetic Scientists of Korea
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• v.45 no.4
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• pp.353-361
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• 2019

Using Fervidobacterium islandicum AW-1, keratin peptides were produced and confirmed factors related to the scalp and hair. The cytotoxicity and proliferation tests as a function of the concentration of the keratin peptide did not show toxicity and effect on the cellular proliferation in the immortalized human hair dermal papilla cell line. Hair shampoos and hair essences containing keratin peptides were produced, and conducted human patch test. Result showed no skin irritation. The shampoo and the essence were apploed to 2 groups of 30 healthy adults for 4 weeks and showed statistically significant positive results for gloss, hair loss, scalp trouble, and hair roughness by visual assessment. The scalp water content was significantly increased after 2 and 4 weeks compared to before using the shampoo or the essence. Trans-epidermal water loss (TEWL) and the sebum secretion amount in the scalp were significantly decreased after 4 weeks compared to before. The frictional force against combing before and after using the hair shampoo and the essence for normal hair tress and damaged hair tress was significantly changed. The combing force was increased for normal hair tress and decreased for damaged hair tress. In conclusion, we suggest that keratin peptides are appropriated as cosmetic ingredients to be used in hair and scalp related products.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.10a
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• pp.1416-1419
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• 2015

최근 건강에 대한 일반인들의 관심이 증가하면서 스마트 헬스케어 시장 규모가 기하급수적으로 커지고 있다. 특히 탈모 관련 헬스케어 시장의 경우, 국내 탈모 인구의 증가로 인해 탈모의 예방이나 관리 등 탈모 관련 어플리케이션이 빠르게 등장하고 있다. 모발 밀도는 탈모의 정도를 판단하기 위한 가장 기본적인 모발 특징 중 하나이지만, 모발의 밀도를 측정하기 위한 명확한 영상처리 기법이나 소프트웨어의 개발은 여전히 미진한 상태이다. 이에 본 논문에서는 스마트폰에 탈부착이 가능한 포터블 카메라에서 촬영된 두피 모발 현미경 영상에서 모발의 밀도를 측정하고 이를 기반으로 사용자 중심의 탈모 진단 플랫폼을 구축하고자 한다. 모발 밀도의 측정은 Contrast Stretching과 Morphology Processing을 이용한 전처리, 스켈레톤 이미지의 변환, 그리고 라인 끝점 검색 알고리즘의 적용 등 크게 세 단계로 진행된다. 제안하는 기법의 성능 평가를 위해, 50배율 포터블 카메라로 촬영한 두피 영상 30개에 대해 밀도 측정을 수행하였으며 그 결과 92.88%의 정확도를 얻었다. 결과적으로 제안하는 기법은 단순 두피 현미경 영상으로 탈모의 지표가 될 수 있는 모발 밀도를 측정하는 데 충분히 효과적임을 알 수 있다.

• Korean Journal of Food Science and Technology
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• v.43 no.3
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• pp.381-386
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• 2011

This study investigated the effect of herbal extracts fermented by Lactobacillus plantarum (MBN) on hair growth in C57BL/6 mice and HaCaT cells. Five week old mice were applied with MBN topically (0.2 mL) once per for 21 days. Hair regrowth was evaluated by gross examination and verified by hematoxylin-eosin staining. Gene expression of vascular endothelial growth factor (VEGF), keratinocyte growth factor (KGF), and transforming growth factor-beta1 ($TGF{\beta}1$), relevant to hair growth, were examined. The data revealed that MBN successfully promoted hair growth in both male and female mice at a dose between 200-500 mg/kg and improved hair thickness. The VEGF and KGF genes were expressed in a dose-dependant manner, whereas $TGF{\beta}1$ was not expressed. Moreover, nitric oxide was significantly increased, suggesting an improvement in blood flow. These results indicate that MBN effectively promoted hair growth and gene expression relevant to hair growth in an animal model.

• The Journal of the Convergence on Culture Technology
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• v.10 no.2
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• pp.547-553
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• 2024

If congenital fever left untreated, it can cause atopic dermatitis. It is very important to manage the surface temperature of the neonatal's head during sleep. Baby pillows were mostly developed with cotton materials due to their delicate skin, or they were used for head correction due to their flexible skeletons. This paper measured the surface temperature of baby head in a sleep and analyzed the trends to figure out the PCM effect which to prevent the congenital fever. In addition it was performed a usability evaluation from baby's parents to investigate their satisfaction. According to the results, PCM is effective in regulating skin temperature of neonatal's head to prevent the congenital fever.

• Pediatric Infection and Vaccine
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• v.29 no.2
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• pp.118-123
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• 2022

A dermatophyte is a zoonotic infection that causes infection on the skin, hair, and nails and is transmitted through contact. The species of Microsporum, Trichophyton, and Epidermophyton are the major dermatophytes that infect humans. Tinea capitis is a dermatophyte infection in the scalp, and it may progress to kerion celsi, including severe redness, swelling, and pus formation. Kerion celsi is sometimes misdiagnosed as a bacterial infection or a tumor. Trichophyton verrucosum is a zoophilic dermatophyte that mainly causes infection in cattle. It can be spread to dairy farmers or ranchers who have frequent contact with infected cattle. We report a pediatric case who received scalp tumor excision and a split-thickness skin graft for extensive and severe inflammatory scalp tumors that occurred after contact with cattle with ringworm. Finally, the patient was diagnosed with kerion celsi caused by T. verrucosum infection. This was based on the patient's medical history, clinical manifestations, and histopathologic findings.

• Journal of Science Education
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• v.33 no.2
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• pp.173-183
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• 2009

We aimed to examine difference between the brain activation pattern based upon hypothesis-generating and hypothesis-understanding among the pre-service teachers not majoring in biology, the pre-service teachers majoring in biology and the biologists using fMRI. We have designed two sets of task paradigm on the biological phenomena: hypothesis-generating and hypothesis-understanding and thirty six healthy participants (twelve participants per group) performed the tasks. The result was showed that 1) there were significant differences of brain activation patterns in hypothesis-generating on the biological phenomena among three groups, 2) the left middle frontal gyrus in the part of DLPFC region was play an important roles of hypothesis-generating and make a significant differences among three groups. The superior ability of biologists were based upon the activation of middle frontal gyrus which has secondary integration of abstract information, and 3) there were no significant differences of brain activation patterns in hypothesis-understanding on the biological phenomena among three groups. These findings provided that scientist might be skillful in generating a new scientific knowledge.

• Science of Emotion and Sensibility
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• v.19 no.4
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• pp.119-126
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• 2016

In this study, we investigated the effects of mouth breathing on brain activity through electroencephalogram (EEG). EEG was performed on 12 healthy volunteers of age ranging from 21 to 27 years (male: female = 6:6, non-smoker). Brain waves on resting state (Rest_N/Rest_M) and auditory-language stimuli state (Eng_N/Eng_M) were recorded during mouth and nose breathing. Four different regions (R1~R4) were classified based on the brain functionality. And each channel (e.g., Pf1 and Pf2) and frequency (${\alpha}$, ${\beta}$, ${\gamma}$, and ${\theta}$) were analyzed using their absolute power ratios of fast Fourier transform (FFT). The results showed that there was no significant difference between Rest_N and Rest_M. Eng_N had significantly higher brain activity than Rest_N; on the other hand, there was no significant difference between Rest_M and Eng_M. These results demonstrate that mouth-breathing on resting state does not induce any significant effects on brain activity and/or functionality, even though it causes subtle temporary inconvenience. In addition to the uncomfort, the brain activity can be adversely influenced by mouth-breathing, which could lower the cognitive skills under certain circumstances.