• The Journal of Information Systems
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• v.30 no.1
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• pp.105-121
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• 2021

Purpose Today, through digital services, many people enjoy a conveient and comfortable life. Nevertheless, it is easy to find people in our daily lives who are buried in work without any payment that we did not do before digital services. Such un-payed works under digital environment are called digital shadow works. The purpose of this study is to classification and dynamics of digital shadow works and to suggest research direction. Design/methodology/approach Based on two dimension, voluntary participation ('should' type and 'want' type) and work orientation (management-operation), digital shadow works were classified into four categories - chore, makeup, routine, and quest. Findings In digital shadow work there are four types of dynamics - routine and quest, makeup and chore, makeup and quest, and quest and actions in offline. According to the classification and analysis of dynamics, three research directions in digital shadow work are suggested and discussed- digital shadow works operation mechanism considering dynamics, expansion of existing user theories based on survey method by digital shadow works and social influences by digital shadow works.

• International Area Studies Review
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• v.15 no.2
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• pp.331-350
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• 2011

This paper analyzes balance of goods for a panel data of 56 industry classification in the MTI from 1980 to 2009. This study also develops the equilibrium adjustment process, which is a trade-off between the adjustment costs towards equilibrium costs for balance of goods and the cost of being in disequilibrium. In this framework, the GMM estimation procedure is used to estimate this dynamic panel model consistently. It is found that equilibrium balances of goods in Korean adjust to the speed is very slow to 0.0389. because of this is necessary to adjust the equilibrium goods balance as the cost of goods balance deficit is larger than by the cost. In addition, the real income elasticity for goods balance of resin in Japan and Korea, the real income elasticity 4.38168 and -0.835225, respectively, the marks were consistent with economic theory. The exchange rate elasticity of goods balance in japan to 0.478435 were found in the inelastic.

• 대한핵의학회:학술대회논문집
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• 1969.12a
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• pp.10-10
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• 1969

• 대한핵의학회:학술대회논문집
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• 1970.10a
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• pp.87.2-88
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• 1970

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2020.10a
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• pp.169-169
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• 2020

• Korean Journal of Clinical Pharmacy
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• v.22 no.1
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• pp.1-8
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• 2012

항혈소판제인 티크로피딘과 항고혈압제인 니칼디핀과의 약동학적 상호작용 연구를 위하여 티크로피딘 (3 또는 10 mg/kg)과 니칼디핀의 경구 (4 mg/kg) 및 정맥 (12 mg/kg) 투여하여 본 연구를 시행하였다. 연구방법: 티크로피딘이 cytochrome P450 (CYP) 3A4 활성과 P-glycoprotein (P-gp)의 활성에 미치는 영향도 평가하였다. 결 과: 티크로피딘과 니칼디핀의 병용투여 시 티크로피딘이 니칼디핀의 약물동태 파라미터에 미치는 결과는 다음과 같다. 티크로피딘은 CYP3A4 효소의 활성을 저해 하였으나 P-gp활성에는 영향을 미치지 못하였다. 니칼디핀의 혈중농도곡선하면적 (AUC)는 대조군에 비해 티크로피딘 10 mg/kg 병용투여군에서 유의성 (p < 0.05)있게 증가되었다. 상대적 생체이용률 (RB)은 티크로피딘 병용투여군에서 115-143%로 증가하였다. 결 론: 본 논문에서 흰쥐에 티크로피딘과 니칼디핀을 병용경구투여 시 니칼디핀의 생체이용률 (bioavailability)이 유의성 (p < 0.05)있게 증가된 것은 티크로피딘이 대사효소인 CYP3A4를 억제하여 소장과 간장에서 초회통과효과 (first-pass metabolism)를 감소 시켰기 때문인 것으로 사료된다. 본 실험결과를 토대로 인체에서 티크로피딘과 니칼디핀의 상호작용을 검토한 후 투여용량을 조절하는 것이 바람직하다고 사료된다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.201-201
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• 1994

항암 및 면역조절작용을 가지고 있으며 그자체가 서방성 prodrug으로서 약효를 나타낼것으로 기대되는 ara-C와 etherphospholipid의 conjugate인 ara-CDP-DL-PCA.2Na의 실험동물(rat)에서의 체내동태를 HPLC 정량법으로 시행 하였다. Ara-CDP-DL-PCA.2Na의 정맥내 투여(20mg/300g)의 경우 혈장중 반감기는 분포상에 있어서는 평균 20min, 소실상 에서는 4.42hr이었다. 분포 용적은 0.1635Lㆍkg$^{-1}$이었고, 전신 clearance 는 25.63ml.$hr^{-1}$.kg$^{-1}$이었다. 한편 AUC는 2601$\mu\textrm{g}$.hr.ml$^{-1}$이었다. 복강내 주사(1g/kg)의 경우 소실상의 반감기는 3.28hr, AUC는 439.3$\mu\textrm{g}$.hr.ml$^{-1}$이었다. 최고 혈중농도 도달시간은 4.4hr이었으며 그때의 농도는 33.19$\mu\textrm{g}$.ml$^{-1}$이었다. 한편 흡수속도 정수는 0.2493$hr^{-1}$이었다. 정맥내 투여에 대한 복강내 투여의 생체 이용율은 1.1252%로 복강내 투여시 흡수율이 좋지 않음을 시사하고 있다. 이는 투여 시료인 micellar solution이 일종의 약물저장 형태로 작용하여 활성물질을 서서히 방출 하기 때문인 것으로 사료된다. 한편 예비적 대사연구결과 TLC에서 뇨나 담즙으로 배설되는 유의한 농도수준의 ara-CDP-DL-PCA.2Na가 없는 것으로 평가되었다. 이는 생체내에서 enzyme등에 의한 대사과정을 거치는 것으로 사료되는바 방사성 동위원소 표지화합물을 이용한 충분한 대사연구가 필요한 것으로 사료된다.

• Environmental and Resource Economics Review
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• v.14 no.4
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• pp.943-964
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• 2005

This study estimated a wide range of stochastic process models using the frameworks of CKLS (1992) and Nowman and Wang (2001). For empirical analysis, the GMM estimation procedure is adopted for the monthly Brent crude oil prices from January 1996 to January 2005. Using the simulated price series, European call option premiums were calculated and compared each other. The empirical results suggest that the crude oil price has a strong dependency of volatility on the price level. Contrary to the results of previous related studies, it shows a weak tendency of mean reversion. In addition, the models provide different implications for pricing derivatives on crude oil.

• Journal of Korean Ophthalmic Optics Society
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• v.14 no.4
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• pp.11-17
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• 2009

Purpose: The purpose of this study is to provide an empirical overview of the import patterns of the Eyeglasses and Contactlens industry. Methods: This study used an Engle-Granger cointegration technique and Johansen's multivariate cointegraion methodology test to check the stationarity of the model. This paper also applies Rolling regression to our model, indicating that Eyeglasses and Contact Lens import is endogenous to the economic variable. Results: The empirical results show how the import in Eyeglasses and Contact Lens is related to the economic variables. Conclusions: This paper shows how the import of Eyeglasses and Contactlens is influenced by economic variables, such as exchange rate and industrial product, and seasonal factors.

• Korean System Dynamics Review
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• v.4 no.1
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• pp.69-91
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• 2003

Using qualitative methods hinged on urban dynamics models, the paper addresses major issues concerned with new administrative capital construction. It tries to summarize the existing debates on new administrative capital construction and reinterpret diverse interacting factors in terms of reinforcing or balancing feedback structure. The paper suggests that understanding up on the dynamic mechanism imbedded in circular causal loop diagrams is the key to set up appropriate proposals and action plans for the new administrative capital, as they would reveal complicated linkages between the Capital Region and the rest, in addition to the urban dynamic of new administrative capital. In the same context, the paper can confirm similar features reflected in the relocation of capital functions at Canberra, Australia and Berlin, Germany. It has paid special attention to the fact that both Australian and German governments altogether stress the positive feedback loops as they have overcome unprecedented political confrontation among rival cities: Basically, they have encouraged gives-and-takes among major stake-holders. These research findings indicate that the future of new administrative capital construction depends on consensus buildings that can accommodate socio-economic and territorial changes between pros and cons. Although further researches and validations are needed, the system approach presented in this paper could assist Korean decision-makers in developing robust and responsive policy initiatives under uncertainties.