• Journal of Korea Multimedia Society
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• v.14 no.3
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• pp.348-355
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• 2011

In this paper, we propose an automatic prostate segmentation method from dynamic magnetic resonance (MR) images. Our method detects contrast-enhanced images among the dynamic MR images using an average intensity analysis. Then, the candidate regions of prostate are detected by the B-spline non-rigid registration and subtraction between the pre-contrast and contrast-enhanced MR images. Finally, the prostate is segmented by performing a dilation operation outward, and sequential shape propagation inward. Our method was validated by ten data sets and the results were compared with the manually segmented results. The average volumetric overlap error was 6.8%, and average absolute volumetric measurement error was 2.5%. Our method could be used for the computer-aided prostate diagnosis, which requires an accurate prostate segmentation.

• Journal of Biomedical Engineering Research
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• v.20 no.3
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• pp.283-290
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• 1999

Because MR(Magnetic Resonance) slice images have much information of functions about body organs, it is very effeclive for diagnoses lo analyze and visualize MR slice images. A visuahzation process is composed of medical image acquisition, preprocessmg, segmentation, inlerpolation, rendering. Segmentation and interpolation among thenl ,1re currenl hot topics because of MR slice image imperfections. This paper proposes a method for segmentalion, mlerpolation respectively and addresses 3 D-visualizmg of a head. We segmented head tissues uomg otructural knowledge of head studied by clinical experiments sequentially. We improved the dynamic elastic inlerpolation to Utilize in concave conlour. We compared the proposed segmentation method and the interpolation method with other methods.

• Journal of Biomedical Engineering Research
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• v.25 no.4
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• pp.243-251
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• 2004

This study was to quantitative analysis compare to dynamic characteristic change of the regional cerebral blood volume (rCBV) after development of cerebral fat embolism in cats using perfusion MR Imaging. Forty-four adult rats were used. Triolein (n = 15), oleic acid (n = 9) and linoleic acid (n = 11) were injected into the internal carotid artery using microcatheter through the transfemoral approach. Polyvinyl alcohol (Ivalon) (n = 9) was injected as a control group. Perfusion MR images were obtained at 30 minutes and 2 hours after embolization, based on T2 and diffusion-weighted images. The data was time-to-signal intensity curve and ΔR$_2$＊ curve were obtained continuously with the aid of home-maid image proc in.leased significantly at 2 hours compared with those of 30 minutes (P＜0.005). In conclusion, cerebral blood flow decreased in cerebral fat embolism immediately after embolization and recovered remarkably in time course. It is thought that clinically informations to dynamic characteristic change of the cerebral hemodynamics to the early finding in cerebral infarction by DWI and PWI

• Journal of radiological science and technology
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• v.27 no.4
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• pp.17-21
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• 2004

With advancement of the medical imaging technology, the dynamic pelvic MRI (magnetic resonance imaging) has been introduced and used for dynamic MR defecography to improved diagnosis of the patients. At the early stage of its use, it was mostly used to diagnose enterocele or cystocele, then its use was extended to diagnose the organ prolapse and other dysfunctional pelvis organs. There now have been many reports of other diseases such as the functional constipation and others. This paper introduces the pelvis MRI and the dynamic MR defecography and reports the future trend in their clinical applications. Until recently, the studies with pelvic MRI were mostly focused on observing the movement of the pelvis in the supine position. Yang and 26 others reported good result in observing the patients with the pelvic organ prolapse by using the pubococcygeal line as the anatomical index. Using the fast gradient recalled acquisition (fast GRASS), they compared cystocoele, genitourinary prolapse, enterocoele and rectocoele with the control group. Kruyt et al. observed the posterior compartment and reported that MRI was more helpful than the fluoroscopy. Healy et al. applied the dynamic MRI test on the patients with constipation or incontinence as well as the control group without those symptoms. Since then, MRI technology has further advance by Lienemann, who was able to attain the more detailed images using the fast T2 weighted turbo spin echo technology, and others. If its limitation in diagnosing intussusception and the like, since the observation can be made only from the supine position, can be overcome with open MR or others, it is envisages that the method can eventually replace the radiological defecography.

• Broadcasting and Media Magazine
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• v.24 no.3
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• pp.35-49
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• 2019

본 고에서는 혼합현실(Mixed Reality, MR) 기반의 서비스를 위한 제작과 관련된 동향과 기술에 대해서 살펴본다. MR이란 증강현실과 가상현실의 장점을 통합하고 사용자와의 인터랙션을 더욱 강화한 방식으로 정의할 수 있는데, 이를 위해 사람에 대해 실사 형태를 가지면서 360도의 전방위 관찰이 가능한 동적인 3D모델 제작기술이 가장 핵심적인 요소이다. 특히 MR 기술 중에서 최근 5G 및 6G 기술의 시대와 함께 실사 객체 및 장면에 대한 3차원 그래픽스와 영상처리 기술을 이용한 6DoF 기반의 실사 애니메이션 제작 기술에 대해서 주로 다루고자 한다. 또한 국내외 기술적 수준을 바탕으로 국내외 시장 동향에 대해서 살펴보고, MR 기술이 시장에 미치는 파급효과와 활용 분야에 대해서도 다룬다.

• Investigative Magnetic Resonance Imaging
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• v.14 no.1
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• pp.10-20
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• 2010

Purpose : Recently, the Recon Challenge at the 2009 ISMRM workshop on Data Sampling and Image Reconstruction at Sedona, Arizona was held to evaluate feasibility of highly accelerated acquisition of time resolved contrast enhanced MR angiography. This paper provides the step-by-step description of the winning results of k-t FOCUSS in this competition. Materials and Methods : In previous works, we proved that k-t FOCUSS algorithm successfully solves the compressed sensing problem even for less sparse cardiac cine applications. Therefore, using k-t FOCUSS, very accurate time resolved contrast enhanced MR angiography can be reconstructed. Accelerated radial trajectory data were synthetized from X-ray cerebral angiography images and provided by the organizing committee, and radiologists double blindly evaluated each reconstruction result with respect to the ground-truth data. Results : The reconstructed results at various acceleration factors demonstrate that each components of compressed sensing, such as sparsifying transform and incoherent sampling patterns, etc can have profound effects on the final reconstruction results. Conclusion : From reconstructed results, we see that the compressed sensing dynamic MR imaging algorithm, k-t FOCUSS enables high resolution time resolved contrast enhanced MR angiography.

• Progress in Medical Physics
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• v.9 no.1
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• pp.47-53
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• 1998

Nuclear Medicine Images have comparatively poor spatial resolution, making it difficult to relate the functional information which they contain to precise anatomical structures. Anatomical structures useful in the interpretation of SPECT /PET Images were radiolabelled. PET/SPECT Images Provide functional information, whereas MRI mainly demonstrate morphology and anatomical. Fusion or Image Registration improves the information obtained by correlating images from various modalities. Brain Scan were studied on one or more occations using MRI and SPECT. The data were aligned using a point pair methods and surface matching. SPECT and MR Images was tested using a three dimensional water fillable Hoffman Brain Phantom with small marker and PET and MR Image was tested using a patient data. Registration of SPECT and MR Images is feasible and allows more accurate anatomic assessment of sites of abnormal uptake in radiolabeled studies. Point based registration was accurate and easily implemented three dimensional registration of multimodality data set for fusion of clinical anatomic and functional imaging modalities. Accuracy of a surface matching algorithm and homologous feature pair matching for three dimensional image registration of Single Photon Emission Computed Tomography Emission Computed Tomography (SPECT), Positron Emission Tomography (PET) and Magnetic Resonance Images(MRD was tested using a three dimensional water fill able brain phantom and Patients data. Transformation parameter for translation and scaling were determined by homologous feature point pair to match each SPECT and PET scan with MR images.

• The Korean Journal of Nuclear Medicine
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• v.32 no.4
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• pp.332-343
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• 1998

Purpose: The purpose of this study was to assess the diagnostic accuracy of various quantitation methods using F-18-fluorodeoxyglucose (FDG) in patients with malignant or benign lung lesion. Materials and Methods: 22 patients (13 malignant including 5 bronchoalverolar cell cancer; 9 benign lesions including 1 hamartoma and 8 active inflammation) were studied after overnight fasting. We performed dynamic PET imaging for 56 min after injection of 370 MBq (10 mCi) of FDG. Standardized uptake values normalized to patient's body weight and plasma glucose concentration (SUVglu) were calculated. The uptake rate constant of FDG and glucose metabolic rate were quantified using Patlak graphical analysis (Kpat and MRpat), three compartment-five parameter model (K5p, MR5p), and six parameter model taking into account heterogeneity of tumor tissue (K6p, MR6p). Areas under receiver operating characteristic curves (ROC) were calculated for each method. Results: There was no significant difference of rate constant or glucose metabolic rate measured by various quantitation methods between malignant and benign lesions. The area under ROC curve were 0.73 for SUVglu, 0.66 for Kpat, 0.77 for MRpat, 0.71 for K5p, 0.73 for MR5p, 0.70 for K6p, and 0.78 for MR6p. No significant difference of area under the ROC curve between these methods was observed except the area between Kpat vs. MRpat (p<0.05). Conclusion: Quantitative methods did not improve diagnostic accuracy in comparison with nonkinetic methods. However, the clinical utility of these methods needs to be evaluated further in patients with low pretest likelihood of active inflammation or bronchoalveolar cell carcinoma.

• The Journal of the Korea Contents Association
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• v.5 no.5
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• pp.296-304
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• 2005

Quantitative analysis compare to dynamic characteristic change of the regional cerebral blood volume(rCBV) after development of cerebral fat embolism in cats using perfusion magnetic resonance(MR) Imaging. Twenty cats were used. Linoleic acid (n=11) were injected into the internal carotid artery using microcatheter through the transfemoral approach. Polyvinyl alcohol (Ivalon) (n=9) was injected as a control group. Perfusion MR images were obtained at 30 minutes and 2 hours after embolization, based on T2 and diffusion-weighted images. The data was time-to-signal intensity curve and ${\Delta}R_2^*$ curve were obtained continuously with the aid of home-maid image process algorithm and IDL(interactive data Banguage, USA) softwares. The ratios of rCBV increased significantly at 2 hours compared with those of 30 minutes (P<0.005). In conclusion, cerebral blood flow decreased in cerebral fat embolism immediately after embolization and recovered remarkably in time course. It is thought that clinically informations to dynamic characteristic change of the cerebral hemodynamics to the early finding in cerebral infarction by diffusion weighted imaging(DWI) and perfusion weighted imaging(PWI).

• The Journal of the Korea Contents Association
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• v.19 no.11
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• pp.445-450
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• 2019

This study proves that syringe reuse of automated injection system entails a risk of contrast media reflux and saline solution contamination which are pumped by a piston into the patients' venous cannula in the dynamic MR images, we will be aware of the serious problem. To quantify the contrast media contamination effect on the saline solution, identical volume of the saline solution was collected before and after the contrast injection to the patients' venous cannula following T1 weighted image scanning to verify whether signal intensities differences are observed. The signal intensity of saline solution after the contrast injection was significantly higher than that of saline before injection by 523.43%. This result is due to the backflow that contaminates the saline solution on the opposite side when the contrast agent is injected. In conclusion, the syringe used to inject contrast medium. causes cross-contamination due to contrast reflux. Therefore, even if the same patient's examination is used for quantitative analysis, the error should be avoided by changing the acquisition sequence or replacing the syringe.