• Korean Journal of Social Welfare Studies
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• no.36
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• pp.253-280
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• 2008

Previous research indicates that depressive symptoms and alcohol consumption are highly correlated with each other. However, there is lack of consensus on the causal relationship between depressive symptoms and alcohol use. In order to address this limitation, this paper examines causal relationship between the two variables using non-recursive structural equation modeling, controlling sociodemographic and psycho-socio-behavioral variables. Data included 14,469 community dwelling individuals who participated in Korea Welfare Panel Study in 2006. Results showed that the effects of alcohol consumption on depressive symptoms was statistically significant, whereas the effects of depressive symptoms on alcohol consumption was not. Significant portions of the effects of psycho-socio-behavioral variables on depressive symptoms were indirect through their effects on alcohol consumption. Based on the results, implications for intervention and future research were discussed.

• 한국사회복지학회:학술대회논문집
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• 2007.10a
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• pp.231-238
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• 2007

• 월간산업보건
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• s.293
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• pp.17-22
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• 2012

• Journal of Internet Computing and Services
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• v.19 no.4
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• pp.83-93
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• 2018

This study analyzed the effects of women's SNS use on their alternative behaviors of managing health. This study paid attention to how women's behaviors of seeking information about poisonous menstrual products and alternative menstrual products would impact their intention to use alternative menstrual products. Mainly based on health belief model, 11 hypotheses were created and tested through a path analysis of survey data. Results from the path analysis indicated that SNS information about menstrual products were significantly associated with perceived advantage of alternative menstrual products and perceived sensitivity of poisonous menstrual products. In addition, four main factors-self-efficacy, perceived sensitivity, perceived advantage, and perceived disadvantage-were significantly associated with women's intention to use alternative menstrual products.

• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 1991.05a
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• pp.8-12
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• 1991

Biodegradation of carbon tetrachloride (CTC) in denitrifying and aerobic columns was investigated under various conditions of electron-acceptor and electron-donor availability. CTC removal increased when the electron-acceptor (nitrate) injection was stopped in the denitrifying column ; however, CTC removal decreased when electron donor (acetate) was deleted in the denitrifying and the aerobic column. Small fractions of the CTC removed appeared as chloroform, indicating that reductive dechlorination of CTC was occurring. The results from the denitrifying column support the hypothesis that CTC behave as an electron acceptor that competes for the pool of available electrons inside the bacterial cells.

• Korean Journal of Social Welfare
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• v.63 no.1
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• pp.187-215
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• 2011

This study examined the longitudinal relationship between depressive symptoms and alcohol use based on the tension reduction hypothesis and the intoxication hypothesis considering for path of depressive symptoms on alcohol use and vice versa simultaneously. And this study examined the effect of psychosocial behavior factors (i.e. smoking level, self-esteem, satisfaction with family relationships, and satisfaction with social relationships) on depressive symptoms and alcohol use. Using the data on the Korea Welfare Panel Study for the 1st, 2nd, and 3rd years, this study were estimated using the Latent Growth Curve Model which is helpful for examining differences between the two. The results are as follows: the initial level of alcohol use had a positive impact on the rate of change in depressive symptoms, thereby supporting the intoxication hypothesis. Second, self-esteem and satisfaction with family relationships act as variables with the biggest effect on the initial level and the rate of change in depressive symptoms, whereas other psychosocial behavior factors such as smoking level and satisfaction with social relationship exert the largest influence over the initial level and the rate of change in alcohol use. This study has implications in that it clarified the confused relationship mechanism between alcohol use and depressive symptoms the two. Based on the finding of the study, political and practical implications were discussed.

• Biomedical Science Letters
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• v.6 no.1
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• pp.29-36
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• 2000

To investigate the effect of injection frequency of bromobenzene on the liver damage, bromobenzene (400 mg/kg, i.p.) was given daily to rats for six days. All experimental animals were sacrificed at 24 hours after the last injection. Morphological changes of the liver were observed under a light microscopic examination. Functional changes of the liver were evaluated by the measurement of alanine aminotransferase activity. To clarify the cause of discrepancy in liver damage, hepatic glutathione (GSH) content, glutathione S-transferase (GST) and aniline hydroxylase (AH) activities were determined. In the experiments of daily bromobenzene treatments, the sacrificed animals at six day (6 time-injected animals) showed slighter liver damage than those sacrificed at 3 day (3 time-injected ones), based on the liver morphological or functional findings; the decreasing ratio of GSH content and increasing ratio of liver GST and AH activities in the 6 time-injected group were higher than those in the 3 time-injected one.

• Korean Journal Plant Pathology
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• v.2 no.2
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• pp.89-95
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• 1986

The five short-chain fatty acids such as isobutyric(C-4), butyric(C-4), isovaleric(C-5), valeric(C-5) and caproic (C-6) acids obtained from the extract of common purslane showed wide antifungal spectra against spore germination and mycelial growth of the twenty five phytopathogenic fungi tested in vitro, although there were differences in antifungal potency among them. The antifungal potency of each fatty acid varied significantly against different fungi in spore germination and mycelial growth. The seventeen fungi used for spore germination test and the sixteen fungi used for mycelial growth test can be divided into three groups depending upon differences in minimal inhibitory concentration of each fatty acid for them, respectively. Caproic acid was significantly more toxic to germination than to mycelial growth of the test fungi, while the other four fatty acids did not show such a significant differences in toxicity with a few of exceptions as shown in valerie acid. The longer the chain-length of fatty acid was, the higher the antifungal potency was shown. The normal fatty acids such as butyric and valerie acid were more toxic than their isomers to spore germination and mycelial growth of the test fungi. Each fatty acid was more toxic to spore germination of obligate parasites and some of facultative parasites, and mycelial growth of facultative parasites than to spore germination and mycelial growth of saprophytes, respectively.

• Korean journal of applied entomology
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• v.55 no.3
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• pp.267-275
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• 2016

Chlorine dioxide has an insecticidal activity via its production of reactive oxygen species (ROS). Its cytotoxic activity has been regarded as a main cause of the insecticidal activity. This study tested a hypothesis that cytotoxicity of chlorine dioxide is resulted from its induction of apoptosis against target cells using ROS. Injection of chlorine dioxide significantly reduced total hemocyte counts of Plodia interpunctella larvae and subsequently killed the larvae. To analyze the cytotoxicity with respect to apoptosis, terminal deoxyribonucleotidyl transferase nick end translation (TUNEL) assay was performed. An insect cell line (Sf9) cells were exposed to different concentrations of chlorine dioxide. TUNEL assay showed that chlorine dioxide induced significant apoptosis of Sf9 cells in a dose-dependent manner. When different concentrations of chlorine dioxide were injected to larvae of P. interpunctella, it showed a dose-dependent induction of apoptosis against hemocytes. However, addition of vitamin E significantly suppressed the apoptosis induction and insecticidal activity of chlorine dioxide in a dose-dependent manner. These results suggest that cytotoxicity of chlorine dioxide is resulted from its induction of apoptosis against insect cells using ROS.

• Korean Journal of Environmental Agriculture
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• v.10 no.2
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• pp.167-177
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• 1991

O-ethyl S-methyl ethylphosphonothioate [$LD_{50}$ (rat, oral) 4.6mg/kg ; $K_i$(bovine erythrocyte acetylcholinesterase) 303 $M^{-1\;min-1}$] was selected as a model compound to study the mode of action of O, S-dialkyl alkylphosphonothioates which have been hypothesized to be toxic via a bioactivation process. Two chemical oxidants, meta-chloroperoxybenzoic acid and monoperoxyphthalic acid, and rat liver microsomal oxidases were used to mimic the action of mixed function oxidases on the model compound. The formation of S-oxide, a very unstable active intermediate, was proposed based on the identification of metabolic products.Furthermore, a trapping experiment with ethanol showed that the unstable intermediate S-oxide had the ability to phosphorylate acetylcholinesterase which is an important enzyme in nerve systems. The S-oxide intermediates are presumed to be responsible for the toxicity of O,S-dialkyl alkylphosphonothioates.