Kwak, Seung-Jin;Noh, Younghee;Chang, Inho;Ko, Jae Min
Journal of Korean Library and Information Science Society
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v.53
no.2
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pp.73-94
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2022
This study is a basic research for establishing a mid- to long-term development plan for the library of the Korea Expressway Corporation that can establish the vision and core values of the library and continuously grow by taking advantage of the specialization of the road transportation field in preparation for the 4th industrial revolution and post-corona era. The current state, satisfaction, and demand of the library were conducted for users of the Korea Expressway Corporation, and based on this, a mid- to long-term development plan was proposed. As a result of the research, first, the library of the Korea Expressway Corporation should provide information services to respond to the immediate information needs of its members as a library that supports academic and research activities as well as the comprehensive collection and preservation of related materials as a national road transportation representative library. Second, it is necessary to establish a systematic collection development policy, and it is necessary to collect collections by detailed themes related to road traffic. Third, overall service development is necessary, and Korea Expressway Corporation library homepage and mobile service should be developed. Lastly, space improvement must be made through space reorganization, and it is necessary to expand the usability through the introduction of the latest technology.
CopA3 (LLCIALRKK), an antimicrobial peptide isolated from the Korean dung beetle, has been shown to suppress apoptosis in various cell types. CopA3 inhibits not only bacterial toxin-induced colonocyte apoptosis but also 6-hydroxy dopamine-induced neural cell apoptosis. Our recent study revealed that CopA3 directly binds to caspases (key regulators of apoptosis) and inhibits the proteolytic cleavage required for their activation. But molecular mechanisms underlying CopA3-mediated inhibition of apoptosis in multiple cell types remain unknown. Here we assessed possible effects of CopA3 on expression of survivin, which is known to inhibit apoptosis. In HT29 human colonocytes, CopA3 exposure markedly upregulated survivin expression in a concentration- and time-dependent manner. RT-PCR revealed that CopA3-mediated upregulation of survivin was attributable to increased gene transcription, and further showed that CopA3 also increased expression of Sp1, one of many transcription factors known to be involved in transcription of the survivin gene. Notably, blocking Sp1 by treatment with the Sp1 inhibitor, tolfenamic acid, significantly reduced CopA3-mediated upregulation of survivin. These results collectively suggest that CopA3 induces Sp1 expression, which in turn is involved in upregulation of survivin in human colonocytes. These novel findings establish another pathway for explaining the anti-apoptotic effects of CopA3 against various cellular apoptosis systems.
Journal of the Korean Applied Science and Technology
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v.39
no.1
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pp.42-51
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2022
This study was conducted to identify the factors affecting the problem solving ability in nursing students. Method: The subjects of this study were 226 nursing students from two universities located in G and C provinces. The collected data were analyzed by t-test, ANOVA, Correlation Coefficient, and Multiple Regression Analysis. Results: As a result of multiple regression analysis, the significant predictors of problem solving ability of nursing students were critical thinking disposition(β=.490, p<.001) and self-directed learning ability(β=.355, p=<.014). Problem solving ability was explained 61.9% of variance in critical thinking disposition and self-directed learning ability. Conclusion: The results of this study showed that self-directed learning ability and critical thinking disposition in nursing students were the influential factor on problem solving ability. Therefore, the results of this study suggest that it is necessary to find ways to improve critical thinking disposition and self-directed learning ability in order to improve problem solving ability of nursing students, and it is considered to be useful as basic data for developing education programs to improve problem solving ability.
Journal of Korea Entertainment Industry Association
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v.15
no.7
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pp.45-57
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2021
The purpose of this study is to identify what factors have impacts on the amount of YouTube viewing. In doing so, usage type, children's levels of self-control on viewing, parent's perception of media contents, and parental mediation style were investigated by age. The result of the study showed no significant differences of the amount of use by the different age groups. There were, however, significant differences in terms of subscription status(non subscription based vs. subscription-based viewing), level of self-control, perception of content, and parent's mediations (technology, supervision, and guidance). Given the amount of YouTube use, the subscription status and parent's supervision were significantly influential factors for the age group of 3-4 years old. For the age group of 5-6, subscription status, levels of self-control, and mediation of parent's supervision and guidance were influential factors. For the age of 7-9, subscription status, the level of self control, and premium service were significantly influential. Finding similarities and differences in meaningful variables by age group suggests that different strategies should be used to reduce the amount of children's YouTube use. In addition, it raises the need for a more detailed classification of children's YouTube usage methods, which have not been addressed so far, and the need for research on the influence of these methods.
The Journal of the Convergence on Culture Technology
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v.8
no.6
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pp.9-22
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2022
The purpose of this study was to provide basic data on pre-service teacher's education based on cooperative learning-oriented teaching and learning methods by applying cooperative learning to verify the effectiveness of pre-service early childhood teacher's communication and problem-solving ability. In the first semester of 2021, 4th grade students who took the teaching method by subject class opened by department of early childhood education at C university were taught for 11 weeks from March 1st week to May 2nd week in 2021 for 4 hours a week. The results of this study were as follows: First, the average score of interpretive ability was the highest in the sub-areas of communication ability of pre-service early childhood teachers, followed by message conversion ability, role performance ability, self-presentation ability, and goal setting ability in the cooperative learning-oriented teaching method by subject class. Second, in terms of the overall average score of pre-service teacher's problem-solving ability, the average score of post-test was increased compared to the average score of pre-test. Through the cooperative learning-oriented class experience in the university's early childhood teacher training course, it is possible to cultivate the practical ability that can be used variously for the children such as communication ability and problem-solving ability in the early childhood education field. Therefore, it is necessary to provide opportunities for cooperative learning-oriented teaching methods in the teacher's education curriculum.
Journal of the Korean Society for Library and Information Science
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v.56
no.1
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pp.67-93
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2022
This study purposes for the based data for establishing the mid- to long term development direction of Anyang municipal libraries by conducting a survey of residents in Anyang city and focus group interviews with local experts. Based on the results of the survey and FGI analysis conducted in this study, the main implications and discussions for establishing mid- to long term development plans for Anyang municipal libraries in the future are summarized as follows. First, the services used by users are extremely limited compared to the utilization rate of library, and the utilization rate of library programs is low, therefore Anyang municipal libraries need to actively promote various services operated by the library, provide information, and make efforts to improve service use procedures simply. Second, library satisfaction is relatively high, but as a result of analyzing the reasons for some dissatisfaction, active budget investment for purchasing new library materials and ways to increase library accessibility are necessary. Third, due to the low awareness of the operation of specialized libraries, it is necessary to develop specialized, unique library services to Anyang municipal libraries through benchmarking of other best practices. Fourth, in the future, Anyang municipal libraries need to strengthen functions as a complex cultural center along with the functions as an information center, a lifelong education center, and a living convenience center. Lastly, it is required to construct a control tower that can systematically lead the operation of Anyang municipal libraries in the long term through the reorganization of the organizational system.
Journal of the Computational Structural Engineering Institute of Korea
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v.35
no.1
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pp.57-64
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2022
This study investigated the structural performance of the RC boundary beam-wall system subjected to axial loads that required lesser construction quantity and smaller floor height in comparison with the conventional RC transfer girder system. Four specimens of 1/2 scale were constructed, and their peak strengths under axial loads and failure characteristics were compared and analyzed. Test parameters included the ratio of the lower to the upper wall length, lower wall thickness, and stirrup details of the lower wall. In addition, three-dimensional nonlinear finite element analysis was performed to verify the effectiveness of the boundary beam-wall system. The peak strength of each specimen was similar to the nominal axial strength of the lower wall, indicating that the axial load was transferred smoothly from the upper to the lower wall. The contribution of the lower wall cross-section was high if the ratio of the lower to the upper wall length was small; the contribution was low if the out-of-plane eccentricity existed in the lower wall. The specimen with smaller stirrup distance and cross-ties in the lower wall showed higher initial stiffness and peak load than other specimens.
Selenium is an important trace mineral that plays an essential role in maintaining the body's immunity with oxidative stress defense and antioxidant activity, immunity, thyroid hormone control, defense against drug or heavy metal harm, and reducing the risk of chronic diseases. A selenium deficiency increases the risk of various chronic diseases, such as cancer, cardiovascular disease, diabetes, neurological disease, osteoarthritis, muscle necrosis and weakness, thyroid disease, and inflammatory diseases. This paper explains the criteria for establishing and revising selenium in the 2020 Dietary Reference Intake for Koreans (KDRIs) and reviews the current status of the selenium database and suggestions for setting the 2025 KDRIs in the future. In the 2020 KDRIs, the selenium intake with the maximum plasma selenoprotein P level was used as the criteria. The weight and coefficient of the variation were applied to the Chinese' reported values. Compared to 2015 KDRIs, there were some revisions in the selenium dietary reference intakes by gender and age according to the change in reference weight. To improve and revise selenium dietary reference intakes in the future, a selenium intervention study is needed to determine the maximum level of plasma selenoprotein P in Koreans. In addition, a revision of the selenium database of the nutritional assessment program (CAN-Pro 5.0) is needed. An analysis of the selenium content of foods should be expanded to assess the selenium intake accurately. In addition, research on the relationship between selenium intake and the biological indicators in the body is required for healthy people and subjects of special environments, such as patients and athletes with various oxidative stress.
Kim, Soo Young;Kim, Tae-Suk;Kim, Dai-Jin;Chae, Jeong-Ho;Lee, Chang Uk;Joo, Soo Hyun
Korean Journal of Biological Psychiatry
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v.29
no.1
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pp.22-31
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2022
Objectives Recently, weight loss has emerged as a national concern in South Korea, and this has resulted in an increase in the frequency of use of central nervous system (CNS)-stimulating appetite suppressants. This study aimed to collect cases of psychotic disorders and bipolar disorders triggered by phentermine and phendimetrazine and explore the clinical features and courses. Methods In this retrospective study, we analyzed the electronic medical records of patients and selected eight patients who developed psychotic symptoms and manic symptoms for the first time after taking phentermine and phendimetrazine. All cases were reviewed, and their clinical features and course were summarized. Results All eight patients developed psychotic symptoms, and one had accompanying manic symptoms. The final diagnosis was appetite-suppressant-induced psychotic disorder in four patients, schizophrenia in three, and appetite-suppressant-induced bipolar disorder in one. In addition, three patients were diagnosed as having substance-use disorder. The key psychotic symptoms of these patients were hallucinations and paranoia. Conclusions These case findings suggest that phentermine and phendimetrazine can cause psychotic disorder, bipolar disorder, or substance use disorder and that medical professionals and the public should practice caution when prescribing and using these drugs.
Min Sun Song;Inho Chang;Gum-Sook Hoang;Soo-Kyoung Kim
Journal of the Korean Society for Library and Information Science
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v.57
no.1
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pp.285-308
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2023
This study was carried out to survey and analyze the actual state of reading in Goyang citizens, and to utilize it as a base data for Goyang City's 2nd 'Reading Culture Promotion Plan'. To do this, including references related to reading survey and the 2021 National Reading Survey questionnaire survey questions, the questionnaires that reflected characteristics of adult and student respondents constructed. Then, the survey of 960 adults and 540 students in Goyang City conducted and analyzed the results, and several useful suggestions deduced for 'Goyang City Reading Culture Promotion Plan'. First, the category of reading materials have to be expanded from the paper media to the various media. Second, the expandation of collections in libraries and the services that will help actually buy books are necessary. Third, various reading programs should develop, and the opportunities for citizens to participate in reading and club activities through online should also be increased. Fourth, the facilities and service environments for activating reading should ensure that the accessibility of everyday life. Finally, among the existing reading culture promotion projects, the 'smart libraries', 'Inter-library loan services', 'reading and cultural programs management', and 'Goyang Book Pay' projects need to be sustained and expanded. This study is significant in that it has investigated the actual reading situation of real citizens and has converged the opinions necessary for setting the direction of the effective 'Goyang City reading culture promotion plan'.
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