• Title/Summary/Keyword: 대비효과

Search Result 2,731, Processing Time 0.034 seconds

솔잎 (Pinus Densiflora)부탄올 획분이 간장의 활성산소 및 제거효소에 미치는 영향

  • 김현숙;이지혜;최진호;김대익;박수현;백승진;조원기
    • Journal of Nutrition and Health
    • /
    • v.35 no.3
    • /
    • pp.291-295
    • /
    • 2002
  • This study was designed to investigate the effects of a butanol (BuOH) fraction from an extract of pine (Pinus densiflora Sieb et Zucc.) needles, on oxygen radicals and their scavenger enzymes in the liver membranes of rats. Twenty-eight male Sprague-Dawley (SD) rats were divided into four groups over a 45 days study period: the control group on a basic diet, and three experimental groups on three different dietary levels of the butanol fraction, specifically 25 mg (BuOH-25), 50 mg (BuOH-50), and 100 mg (BuOH-100) butanol fraction/kg body weight/day, thereby 0.025%, 0.05%, 0.1% of butanol extract of pine needles was added to basil diet respectively. At the end of the experimental period, body weights and food intakes were not different among the four groups. The results showed that cholesterol accumulation in the mitochondria and microsomes of liver cells was significantly inhibited in the BuOH-50 and BuOH-100 groups: by 11.6% and 20.1% in the mitochondria of the BuOH-50 and BuOH-100 groups, respectively; and by 10.5%, and 13.5% in the microsomes of the BuOH-50 and BuOH-100 groups, respectively, compared with the control group. The levels of hydroxyl radicals (.OH) were significantly) lower in the liver mitochondria of the BuOH-50 and BuOH-100 groups (by 13.3% and 18.5%, respectively), while OH radicals were significantly lower in the microsomes or all three experimental groups (by 15.7% in the BuOH-25 group, 20.0% in the BuOH-50 group, and 20.6% in the BuOH-100group), compared with the control group. Superoxide radical (O$_2$) formation was also significantly inhibited in the liver cytosol of both BuOH-50 and BuOH-100 groups; the levels of these radicals were 8.0% lower for the BuOH-50 group and 11.1% lower for the BuOH-100 group, compared to the control group. Copper/Zinc - superoxide dismutase (Cu/Zn-SOD) activities were significantly increased (by 10.3% and 15.9%, respectively) in the liver cytosols of the BuOH-50 and BuOH-100 groups, but Mn-SOD activities were almost identical in the three RuOH groups, compared with the control group. Glutathione peroxidase (GPx) activities were significantly increased in the three experimental groups (by 9.0% in the BuOH-25 group, 19.4% in the BuOH-50 group, and by 25.6% in the BuOH-100 group), compared with the control group. These results suggest that the butanol extract of pine needles may play an effective role in attenuating oxygen radicals and activating scavenger enzymes; consequently, aging may be very effectively modulated and/or inhibited.

Effect of Brown Algae (Undaria pinnatifida)-Noodle on Oxygen Radicals and Their Scavenger Enzymes in Liver of Sprague-Dawley Rats (미역 (Undaria pinnatifida) 국수의 투유가 랫트 간장중의 활성산소 및 제거효소에 미치는 영향)

  • CHOI Jin-Ho;KIM Dae-Ik;PARK Soo-Hyun;KIM Dong-Woo;BEAK Yeong-Ho;KIM Chang-Mok
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.33 no.2
    • /
    • pp.87-92
    • /
    • 2000
  • This study was designed to investigate the effects og $10{\%},\;20{\%}\;and\;40{\%}$-addition of functional brown algae (FBA)-noodles on oxygen radicals and their scavenger enzymes in liver of Sprague-Dawley(SD) male rats. Hydroxyl radicals$({\cdot}OH)$ formations were significantly inhibited$(20{\~}35{\%}\;and\;12{\~}20{\%})$ in liver mitochondria and microsomes of rats administered $0{\%},\;20{\%}\;and\;40{\%}$ FBA-noodles compared with that of control group. Significant differences in $H_2O_2$ formations of liver microsome in these FBA-noodles fed groups could not be obtained, but superoxide-radical $(O_2^({\cdot}-))$ formations of liver cytosol resulted in a significant decrease about $10{\%}\;in\;20{\%}\;and\;40{\%}$ FBA-noodles compared with control group. Mn-SOD activities in liver mitochondria were significanlty increased $(10{\~}15{\%})$ in the groups fed $10{\%},\;20{\%}\;and\;40{\%}$ FBA-noodles, while a group administered $40{\%}$ FBA-noodle only resulted In a significant increases $(about 12{\%})$ in Mn-SOD activity of liver microsomes compared with control group. Cu, Zn-SOD activities in liver cytosol were significantly increased $(10{\~}20{\%})\;in\;10{\%},\;20{\%}\;and\;40{\%}$ FEA-noodles compared with control group. Administration of $10{\%},\;20{\%}\;and\;40{\%}$ FBA-noodles resulted in a marked increases$(20{\~}40{\%})$ in liver cytosolic glutathione peroxidase (GSHPx) compared with control group. Significant differences in lipid peroxide (LPO) levels of mitochondria and microsomes in $10{\%}$ FBA-noodle could not be obtained, while LPO levels of $20{\%} and 40{\%}$ FBA-noodles were significantly inhibited about $10{\%}$ in mitochondria and microsomes compared with control group. These results suggest that these FBA-noodles may play a desirable role in attenuating an oxygen radical formations and increasing a scavenger enzymes activity by some brown algae (Undaria pinnatifida) components.

  • PDF

Effect of ${\beta}$-glucan Originated from Aureobasidium on the Dermal Wound Repair in Vitro Model (생체외 모델에서 아우레오바지디움 유래 베타 글루칸이 피부창상 치유에 미치는 영향)

  • Lee, Jung-Woo;Kwon, Young-Sam;Jang, Kwang-Ho
    • Journal of Veterinary Clinics
    • /
    • v.30 no.6
    • /
    • pp.403-408
    • /
    • 2013
  • The objective of the present study is to detect the effect of ${\beta}$-glucan originated from Aureobasidium on the proliferation and collagen production in human dermal fibroblast cells with wound repopulation in vitro. The proliferative effects were assessed using a MTT assay as well as cell counts at 24 and 48 hr after treatment. Hydroxyproline was measured as an index of procollagen production with reverse-phase high pressure liquid chromatography. Oncostatin M was used as a reference agent. In glucagon treated group, dose-dependent and significant increase of optical density or fibroblast cell numbers was demonstrated, when compared with those of control from 0.1 mg/ml concentration. In addition, the numbers of cells which had migrated into the wound defects were more significantly and dose-dependently increased than those of non-treated control. However, no meaningful effects on the procollagen production were observed.

Contrast Enhancement Method using Color Components Analysis (컬러 성분 분석을 이용한 대비 개선 방법)

  • Park, Sang-Hyun
    • The Journal of the Korea institute of electronic communication sciences
    • /
    • v.14 no.4
    • /
    • pp.707-714
    • /
    • 2019
  • Recently, as the sensor network technologies and camera technologies develops, there are increasing needs by combining two technologies to effectively observe or monitor the areas that are difficult for people to access by using the visual sensor network. Since the applications using visual sensors take pictures of the outdoor areas, the images may not be well contrasted due to cloudy weather or low-light time periods such as a sunset. In this paper, we first model the color characteristics according to illumination using the characteristics of visual sensors that continuously capture the same area. Using this model, a new method for improving low contrast images in real time is proposed. In order to make the model, the regions of interest consisting of the same color are set up and the changes of color according to the brightness of images are measured. The gamma function is used to model color characteristics using the measured data. It is shown by experimental results that the proposed method improves the contrast of an image by adjusting the color components of the low contrast image simply and accurately.

21세기 정보기술과 신 군사력 건설방향(2) (네트워크 중심 전투 개념)

  • Kim, Yeong-Gil
    • Defense and Technology
    • /
    • no.5 s.243
    • /
    • pp.44-53
    • /
    • 1999
  • 21세기를 대비하는 미래의 군사력은 정보화의 수준에 따라 전투력 효과가 결정된다. 통합전력의 핵심인 정보화와 군 전력의 네트워크화를 통해 미래의 국가안보를 비용 대 효과적으로 이루어야 할 것이다. 따라서 방위력 개선사업의 골격을 단일 무기체계 획득 중심에서 통합 $C^4I$체계를 비롯한 정보화 체계 중심으로 전환해야 할 것으로 생각된다

  • PDF

The Standards and Effects of Nursing Care through the Development of Treatment Cost Calculation in Hospital Wards ('병동 중심의 처치수가 산정지침 개발' 등을 통한 간호업무 표준화 및 그 효과)

  • Han, Hye-Jeong;Seol, Mi-Jin;Kim, Young-Ju;Park, So-Young;Park, Aris;Moon, Han-Kyung;Lee, Hyun-Young
    • Quality Improvement in Health Care
    • /
    • v.15 no.1
    • /
    • pp.101-111
    • /
    • 2009
  • 문제: 병동 처치수가 산정 부정확 및 누락으로 인한 부적절한 재고관리로 진료차질, 불필요한 업무발생 및 수익이 감소한다. 목적: 병동 처치수가 산정 정확화를 위한 업무 표준화 도구 및 시스템을 개발하여 적정 재고관리를 통한 수익증대 및 직무만족도를 향상시킨다. 의료기관: 서울시 종로구에 소재한 대학병원 질 향상 활동: 병동중심의 처치 산정지침 개발 및 수가물품의 적정재고 관리방안을 모색하였다. 개선효과: 병동중심의 처치수가 산정 지침서를 제작하여 업무표준화를 기하였음. 응급청구 품목 및 수량이 '07년 대비 71%감소하고 타 병동 차용품목이 활동 전에 비해 61% 감소, 수량은 77% 감소함. 응급청구 총소요시간이 활동 전에 비해 '07년 대비 77% 감소하고 타 병동 차용 총 소요시간이 61% 감소함. 전년 동기간 대비 수익이 4% 증가하였으며 또한 54병동과 보험 심사팀에서 직원들의 직무만족도가 향상되었다.

  • PDF

제품안전경영체계에서의 리스크 관리의 역할

  • 이동하
    • Proceedings of the Safety Management and Science Conference
    • /
    • 2001.05a
    • /
    • pp.23-23
    • /
    • 2001
  • 제조물 결함에 의한 기업의 배상책임은 전형적인 기업의 리스크로서 전통적으로 투자, 금융, 보험, 위기 관리, 시스템 안전 분야에서 사용되고 있는 리스크 관리 기법을 적용하여 효과적으로 대비할 수 있다. 현재 일부 선진국에서는 리스크 관리 기법을 규격화하여 각 조직 활동에 잠재된 위험 요소로부터의 손실을 예방하고 기회 이익을 구현하는데 활용하고 있다. 본 연구에서는 현재까지 발표된 호주, 뉴질랜드, 캐나다, 일본, 영국, 유럽연합 등의 나라에서 규격화하고 있는 리스크 관리기법에 대해 비교 검토하고 그 장단점 및 특징을 조사하였다. 또한 제조물 결함에 따른 기업의 배상 책임에 대비하여 기업이 제품 안전 경영체계를 수립하는데 리스크 관리 기법이 적절히 활용될 수 있는지에 대해 토의하였다.

  • PDF

주택경기 동향

  • 한국주택협회
    • 주택과사람들
    • /
    • no.3 s.20
    • /
    • pp.37-49
    • /
    • 1992
  • [ ${\circ}$ ] 9월중 주택경기 동행종합지수는 전월 대비 $0.8{\%}$ 하락한 것으로 나타났음. 이는 내수용 시멘트 출하량, 건설자재용 산업생산지수 등이 감소한 데 기인한 것임. ${\circ}$ $3{\~}4$개월 후의 주택경기를 예고하여 주는 선행종합지수는 ${\ulcorner}7{\cdot}9$신도시 아파트 분양순연조치${\lrcorner}$등 정부의 건설경기 진정책의 효과가 가시화됨에 따라 계절 및 불규칙변동 조정 후의 주택부문 건설수주액 지표 등이 감소하여 전월 대비 $1.1{\%}$ 하락한 것으로 나타났음.

  • PDF