• 한국식품영양학회:학술대회논문집
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• 한국식품영양학회 2000년도 정기총회 및 동계학술심포지움
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• pp.55-55
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• 2000

본 연구에서는 전통적으로 담석증, 신장치료 등의 한약제로 많이 사용하는 대왕을 여러 용매를 사용하여 얻은 대왕추출물 분액에 대한 세포독성을 여부를 MTT 정량법, NR 정량법, SRB 정량법을 이용하여 조사하였다. 1. 추출 용매 methylene chloride, ethyl acetate, butanol, water로부터 얻은 대왕추출물 모두 처리농도에 따라 세포에 미치는 영향이 증가하였다. 2. Butanol을 용매로 사용하여 얻은 대왕추출물 분액이 다른 3가지 용매로부터 얻은 대왕추출물보다 세포에 미치는 영향이 크게 나타났고 water를 용매로 사용하여 얻은 추출물이 A498 세포주에 미치는 영향이 가장 낮게 나타났다. 3. Butanol을 추출 용매로 하여 얻은 대왕추출물이 A498 세포주에 미치는 영향이 가장 컸는데 그 추출물에 대한 MTT50, NR50, SRB50값은 각각 0.63mg/m1, 0.65mg/ml, 0.68mg/ml이었고, 가장 영향이 적은 water의 경우 MTT50, NR50, SRB50값은 각각 0.84mg/m1, 0.82mg/m1, 0.80mg/ml이었다. 4. 정량방법 간의 대왕추출물에 대한 반응은 MTT 정량법이 가장 민감하게 나타났다.

• 셀메드
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• 제13권4호
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• pp.16.1-16.4
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• 2023

Objective: A case report on improving the chronic indigestion and fatigue of patients with cholelithiasis by Ortho-Cellular Nutrition Therapy (OCNT). Methods: A Korean female in her 40s who had a very low quality of life due to chronic indigestion and severe fatigue caused by her diagnosed cholelithiasis. Results: The practice of Ortho-Cellular Nutrition Therapy (OCNT) improved fatigue and problems in gastrointestinal functions. Conclusion: Ortho-Cellular Nutrition Therapy (OCNT) can be effective in relieving the symptoms of patients with problems in gastrointestinal functions.

• Parasites, Hosts and Diseases
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• 제29권2호
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• pp.101-112
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• 1991

한 지역사회에서 최충 감염을 반드시 관리해야 하는 궁극적 이유 또는 그 당위성에 대하여 답하기 어려운 경우가 있다. 그것은 회충 관리 결과 충란 양성률이나 감염량의 감소 이외에 실제로 무엇이 호전되었는지를 알기가 그리 쉽지 않기 때문이다. 이 연구는 우리 나라에서 전국적으로 시행해 온 회을 집단관리 사업이 성공적 결실을 맺게 됨에 따라 국내 각 종합병원급 이상의 담도(또는 담석증), 충수, 췌장 등에 대한 수술 환자 중 회충미립중(迷入症)의 빈도가 크게 감소된 점을 중시하고 이들 외과적 회충중의 감소를 우리 나라 회충 관리의 실질적 효과 중 하나로 제시하고자 하였다. 우리 나라 국민의 회충 감염률 감소 양상은 전국 학생 검변 자료(1969~1989) 및 전국민 장내 기생충 감염현황 자료(1971, '76, '81, '86)에서 파악하였다 외과적 회충증의 빈도는 주로 문헌 고찰에 의하되 1959~1990년 사이에 외과학회지 등에 발표된 담도 질환, 충수염, 췌장염, 장폐쇄 등에 관한 논문을 총 망라하여 참고로 하였다. 분석 결과 종합병원중 이상의 총 담도 수술례(또는 총 담석증례) 중 회충 미립이 차지하는 비율을 YA(또는 YB)라 할 때 YA(또는 YB)의 감소 양상은 전국 학생 회충란 양성률(X)의 감소와 매우 밀접한 순 상관관계를 나타내고 있다는 것을 알 수 있었다. 즉, 수치로 표시하면 $Y_A=0.25X^2+0.013(r=0.96),{\;}Y_B=0.19X^2+0.016(r=0.94)$의 관계를 보였다. 다른 외과적 회충증의 경우에도 담도 회충증과 비슷한 양상을 보였다. 결국 우리 나라의 회충 관리사업은 회충 감염률 및 감염량의 감소 뿐만 아니라 회충 감염시 심각한 합병증의 하나인 담도 회충증 또는 기타 외과적 회충증의 빈도를 격감시키는 데에도 크게 기여한 것으로 판단되었다.

• 대한방사선기술학회지:방사선기술과학
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• 제31권4호
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• pp.323-327
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• 2008

자기양담낭은 담낭 벽에 칼슘이 침착되는 드문 질환이며, 만성담낭염에 의해 벽에 석회화가 일어나거나 결석에 의해 담낭관이 폐색되면서 발생하는 것으로 보고 되고 있다. 자기양담낭은 일반적으로 담낭암을 동반하므로 담낭암을 예방하기 위해 일차적으로 담낭 절제술이 시행된다. 저자들은 증상이 없는 석회화된 담낭을 초음파 검사와 복부 단순방사선검사 및 복부 전산화단층검사를 통해 확인하였고 문헌고찰과 함께 보고하고자 한다.

• 대한방사선기술학회지:방사선기술과학
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• 제21권2호
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• pp.31-35
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• 1998

Gallstone diseases appear frequently in surgical patients. One of the etiolic factors in the formation of cholesterol gallstones is the supersaturation of bile with cholesterol. The bile stasis in the gallbladder may also play a role in the formation of cholesterol gallstones by supplying the proper condition to nucleation of cholesterol crystal. Author evaluated gallbladder empting in response to fat meal by ultrasonography in 12 patients with gallstones and normal control group of 12 healthy subjects. Of the 12 patients with gallstones, six had radiolucent stones and the rest of them had radioopaque stones. Additionally, author evaluated gallbladder contraction in both cholesterol gallstones and pigment gallstones. The gallbladder was significantly contracted in control group by the fat meal but not by water. The contraction of gallbladder by fat meal with gallstone patients was significantly decreased compared with those in control group. The time of maximum contraction was 30 minutes in patients with gallstones. At 30 minutes, the gallbladder contraction was more significantly decreased in patients with radiolucent stones than in those with radioopaque stones. In conclusion, the more significant decrease of gallbladder contraction in patients with radiolucent stones may be interpretated as the possible factor of pathologenesis for the formation of the cholesterol stone.

• Advances in pediatric surgery
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• 제20권2호
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• pp.62-64
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• 2014

Gallbladder stones in children are not common without underlying hemolytic diseases or other risk factors like obesity. Ceftriaxone, a third generation cephalosporin, is known to make biliary precipitations that can be mistaken for biliary stones. We here report two children with biliary pseudolithiasis with different treatment modalities. One child was mistaken for symptomatic gallbladder stones and underwent elective laparoscopic cholecystectomy, while the other child, after thorough history taking on the ceftriaxone medication, was suspected of biliary pseudolithiasis and was treated conservatively. Both children had the history of usage of ceftriaxone in previous hospitals for infectious diseases. The ceftriaxone history of the first child was missed before the surgery. When gallbladder stones are found in children without any underlying diseases, specific history taking of the usage of ceftriaxone seems to be absolutely required. In this case, immediate interruption of the antibiotic could resolve the episode and avoid unnecessary surgical procedure.

• 대한이식학회지
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• 제28권3호
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• pp.160-164
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• 2014

Background: In solid organ transplantation patients, complications of cholelithiasis may run a fulminant course, resulting in high morbidity and mortality under immunosuppression and may even result in rejection. Here, we reviewed medical records of 66 patients in order to determine the outcome of management approach for asymptomatic gallstones in renal transplantation patients. Methods: We retrospectively reviewed clinical courses of 66 cases of renal transplantation performed between 2000 and 2012 at Kosin University Gospel Hospital. Results: Among 66 cases, eight had gallstones before transplantation. Three of these cases had undergone previous cholecystectomy for symptomatic gallstones, one had a simultaneous laparoscopic cholecystectomy and renal transplantation, and four were observed by regular abdominal ultrasonography. One patient was found to have cholangitis, and endoscopic retrograde biliary drainage was performed, resulting in alleviation of symptoms. Among 58 cases without preoperative gallstones, three developed gallstones after transplantation. One patient had cholecystitis, and the symptoms subsided after conservative treatment. Conclusions: For patients with asymptomatic gallstones who are awaiting renal transplantation, expectant management should be considered.

• 대한한의학회지
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• 제45권1호
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• pp.139-149
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• 2024

Objectives: The aim of the study was to investigate the potential of Yangdorak diagnosis application against gallstone scanned by Ultrasound diagnosis. Method: For this aim, among 97 patients who had visited Julip Korean Medicine Clinic from July 2016 to June 2023, 30 patients with no gallstone as a control group and 67 patients with gallstone and diagnosed by ultrasonography, were subjected to Yangdorak diagnosis. Then, the changes in Gallbladder Meridian (GB) value as F5 AVE(average of left and right GB value) by Yangdorak were comparatively analyzed between gallstone and non-gallstone groups and statistical significance was evaluated by Tukey's multiple comparison test using Prism software. Results: After all subjects were evaluated by the Yangdorak and ultrasonography to assess the potential of the Yangdorak diagnosis for gallstone, it was noteworthy that the Yangdorak values relevant to F5 AVE of female gallstone group(N=36) were significantly (p<0.001) decreased compared to the control group (N=30), while there was no significance in male gallstone group(N=31). Also, it was recognized significant difference between male and female groups. Conclusion: Based on these results, if the Yangdorak value can be estimated from a decrease with clinical symptom in female patient, it is recommended to follow up the ultrasonography test for diagnosing the gallstone.

• 대한한방내과학회지
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• 제41권5호
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• pp.761-768
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• 2020

Objectives: The prevalence of cholelithiasis is increasing in both the East and West, and this can have a great impact on the quality of life. This study reports on a patient whose cholelithiasis was improved using Daesiho-tang. Methods: A patient diagnosed with cholelithiasis was treated with acupuncture and herbal medicine. Abdominal pain due to cholelithiasis was evaluated by a numerical rating scale. Results: After 35 days of taking Daesiho-tang, the symptoms of abdominal pain and indigestion improved. Even afterwards, the patient maintained an improved quality of life without recurrence. Conclusions: Korean medicine treatment was effective in improving the symptoms of cholelithiasis. However, studies of various cases will likely be needed in the future.

• 한국식품영양학회지
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• 제13권5호
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• pp.460-464
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• 2000

본 연구에서는 전통적으로 담석증, 신장치료 등의 한약제로 많이 사용하는 대왕을 여러 용매를 사용하여 얻은 대왕추출물 분액에 대한 세포독성을 여부를 MTT 정량법, NR 정량법, SRB 정량법을 이용하여 조사하였다. 1. 추출 용매 methylene chloride, ethyl acetate, butanol, water로부터 얻은 대왕추출물 모두 처리농도에 따라 세포에 미치는 영향이 증가하였다. 2. Butanol을 용매로 사용하여 얻은 대왕추출물 분액이 다른 3가지 용매로부터 얻은 대왕추출물보다 세포에 미치는 영향이 크게 나타났고 water를 용매로 사용하여 얻은 추출물이 A498 세포주에 미치는 영향이 가장 낮게 나타났다. 3. Butanol을 추출 용매로 하여 얻은 대왕추출물이 A498 세포주에 미치는 영향이 가장 컸는데 그 추출물에 대한 MTT$_{50}$, NR$_{50}$, SRB$_{50}$값은 각각 0.63mg/ml, 0.65mg/ml, 0.68mg/ml이었고, 가장 영향이 적은 water의 경우 MTT$_{50}$, NR$_{50}$, SRB$_{50}$값은 각각 0.84mg/ml, 0.82mg/ml, 0.80mg/ml이었다. 4. 정량방법 간의 대왕추출물에 대한 반응은 MTT 정량법이 가장 민감하게 나타났다.