• Korean Journal of Ichthyology
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• v.33 no.4
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• pp.205-216
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• 2021

Phylogenetic reconstruction based on one locus or a few loci can be misleading due to gene-tree/species-tree discordance. Species delimitation and intraspecific studies also often suffered from low resolution because of insufficient statistic power when few loci were used. Exon capture method is one of the most efficient way to collect genome-scale data, which can significantly augment studies that aimed to investigate patterns and histories of organisms at both intraspecific and high level. Here, I showed the advancement of shifting from single-gene method to genomic approach and the benefit of applying exon capture method comparing to alternative genomic techniques. Then, I explained the principle of exon capture method as well as providing detailed recommendations for applying this method. Finally, I demonstrated exon capture method using two applications and discussed future perspectives of this technology.

• Proceedings of the Korea Information Processing Society Conference
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• 2003.11a
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• pp.65-68
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• 2003

본 논문에서는 가장 최근의 동영상 표준인 H.264에서 가변 블록 움직임 예측 시 인접한 블록과의 상관성을 분석하여 병합 절차를 추가함으로써 매크로블록의 최종 모드를 결정하는 시간을 줄이기 위한 알고리즘을 제안한다. H.264에서는 매크로블록의 모드를 결정하기 위하여 총 7가지 모드를 사용하여 움직임 예측은 실시함으로써 부호화 효율을 극대화시킨 반면 이러한 움직임 예측이 부호화기의 복잡도를 높이는 주요 요인으로 현재 커다란 단점으로 지적되고 있다. 본 논문에서는 $8{\times}8$ 움직임 예측이 끝난 후 인접한 두 블록 사이의 거리론 임계값(Threshold)과 비교하여 다음 모드의 움직임 예측의 실시 여부를 먼저 절정함으로써 필요한 움직임 예측에 소비되는 시간을 단축시켰다. 여기서 실험 조건으로 명시하고 있는 것은 대표적인 단일모드 중에서 수행 성능이 가장 좋은 $8{\times}8$ 모드를 기본모드로 사용하고 병합 시 $16{\times}16$ 모드 쪽으로 상향식(bottom-up) 방법의 병합을 수행해 나아간다 모의실험을 통해 수행 성능과 전체 부호화 시간 측면을 본 논문에서 제안한 방법과 4가지 모드인 $16{\times}16,\;16{\times}8,\;8{\times}16,\;8{\times}8$ 모드를 모두 사용한 경우, $8{\times}8$ 단일모드를 사용한 경우를 비교하였다. 실험 결과 $8{\times}8$ 단일모드보다 수행 성능이 향상되었으며, 시간 단축 면에서 제안한 방법이 4가지 모드인 $16{\times}16,\;16{\times}8,\;8{\times}16,\;8{\times}8$ 모드를 모두 사용한 경우와 $8{\times}8$ 단일모드를 사용한 경우보다 계산 시간이 감소하였음을 확인하였다.행중인 MoIM-Messge서버의 네트워크 모듈로 다중 쓰레드 소켓폴링 모델을 적용하였다.n rate compared with conventional face recognition algorithms. 아니라 실내에서도 발생하고 있었다. 정량한 8개 화합물 각각과 총 휘발성 유기화합물의 스피어만 상관계수는 벤젠을 제외하고는 모두 유의하였다. 이중 톨루엔과 크실렌은 총 휘발성 유기화합물과 좋은 상관성 (톨루엔 0.76, 크실렌, 0.87)을 나타내었다. 이 연구는 톨루엔과 크실렌이 총 휘발성 유기화합물의 좋은 지표를 사용될 있고, 톨루엔, 에틸벤젠, 크실렌 등 많은 휘발성 유기화합물의 발생원은 실외뿐 아니라 실내에도 있음을 나타내고 있다.>10)의 $[^{18}F]F_2$를 얻었다. 결론: $^{18}O(p,n)^{18}F$ 핵반응을 이용하여 친전자성 방사성동위원소 $[^{18}F]F_2$를 생산하였다. 표적 챔버는 알루미늄으로 제작하였으며 본 연구에서 연구된 $[^{18}F]F_2$가스는 친핵성 치환반응으로 방사성동위원소를 도입하기 어려운 다양한 방사성의 약품개발에 유용하게 이용될 수 있을 것이다.었으나 움직임 보정 후 영상을 이용하여 비교한 경우, 결합능 변화가 선조체 영역에서 국한되어 나타나며 그 유의성이 움직임 보정 전에 비하여 낮음을 알 수 있었다. 결론: 뇌활성화 과제 수행시에 동반되는 피험자의 머리 움직임에 의하여 도파민 유리가 과대평가되었으며 이는 이 연구에서 제안한 영상정합을 이용한 움직임 보정기법에 의해서 개선되었다. 답이 없는 문제, 문제 만들기, 일반화가 가능한 문제 등으로 보고, 수학적 창의성 중 특히 확산적 사고에 초점을 맞추어 개방형 문제가 확산적 사고의 요소인 유창성, 독창성, 유연성 등에 각각 어떤 영향을 미치는지 20주의 프로그램을 개발, 진행하여 그 효과를 검증하고자 한다. 개방형 문

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.1
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• pp.317-323
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• 2015

This study examined the effects of the Ministry-of-Health-and-Welfare-initiated comprehensive nursing service on the nursing performance, job satisfaction, and customer orientation among nurses. The participants were nurses working in a running hospital without a patient-sitter in S city (Experimental group=57, Control group=55). The data was collected at 1 and 6 months following a pilot program and analyzed by SPSS using a Chi-squire test, t-test, Kolmogorov-Smirnov test and ANCOVA. The experimental group showed significantly better nursing performance, job satisfaction, and customer orientation than the control group. This finding can be used to establish the criteria for systematizing comprehensive nursing service.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.46 no.10
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• pp.814-822
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• 2018

This paper proposes a guidance law for missiles with control time constraint. Because the proposed guidance law is based on a time-to-go polynomial, it has a generalized form. Also, acceleration of the proposed law converges to zero at the end of the control time, which reduces the sensitivity to the time-to-go estimation error and can increase the flight stability when the separation of the missile appears. A prediction method of the time-to-go is proposed for implementing the proposed law, and the possibility of application to the midcourse and terminal guidance phases is dealt with for exoatmospheric interception. The characteristics and performance of the proposed law are analyzed throughout various simulations.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.45 no.2
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• pp.12-19
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• 2022

Artificial intelligence is driving the Fourth Industrial Revolution and is in the spotlight as a general-purpose technology. As the data collection from the battlefield increases rapidly, the need to us artificial intelligence is increasing in the military, but it is still in its early stages. In order to identify maritime targets, Republic of Korea navy acquires images by ISAR(Inverse Synthetic Aperture Radar) of maritime patrol aircraft, and humans make out them. The radar image is displayed by synthesizing signals reflected from the target after radiating radar waves. In addition, day/night and all-weather observations are possible. In this study, an artificial intelligence is used to identify maritime targets based on radar images. Data of radar images of 24 maritime targets in Republic of Korea and North Korea acquired by ISAR were pre-processed, and an artificial intelligence algorithm(ResNet-50) was applied. The accuracy of maritime targets identification showed about 99%. Out of the 81 warship types, 75 types took less than 5 seconds, and 6 types took 15 to 163 seconds.

• Radiation Oncology Journal
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• v.24 no.1
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• pp.11-20
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• 2006

Puroose: In order to find out whether stereotactic radiation therapy (RT) using CyberKnife (CK) could improve survival rate and lower acute toxicity compared to conventional RT. Materials and Methods: From April 2003 through April 2004, 19 patients with Eastern Cooperative Oncology Group (ECOG) performance status ${\leq}3$ and locally advanced pancreas cancer without distant metastasis, evaluated by CT or PET/CT, were included. We administered stereotactic RT consisting of either 33 Gy, 36 Gy or 39 Gy in 3 fractions to 6, 4 and 9 patients, respectively, in an effort to increase the radiation dose step by step, and analyzed the survival rate and gastrointestinal toxicities by the acute radiation morbidity criteria of Radiation Therapeutic Oncology Group (RTOG). Prognostic factors of age, sex, ECOG performance score, chemotherapy, bypass surgery, radiation dose, CA 19-9, planning target volume (PTV), and adjacent organ and vessel invasion on CT scan were evaluated by Log Rank test. Results: The median survival time was 11 months with 1-year survival rate of 36.8%. During follow-up period (range $3{\sim}20$ months, median 10 months), no significant gastrointestinal acute toxicity (RTOG grade 3) was observed. In univariate analysis, age, sex, ECOG performance score, chemotherapy, bypass surgery, radiation dose, CA 19-9 level, and adjacent organ and vessel invasion did not show any significant changes of survival rate, however, patients with PTV (80 cc showed more favorable survival rate than those with PTV>80 cc (p-value<0.05). In multivariate analysis, age younger than 65 years and PTV>80 cc showed better survival rate. Conclusion: In terms of survival, the efficacy of stereotactic radiation therapy using CK was found to be superior or similar to other recent studies achieved with conventional RT with intensive chemotherapy, high dose conformal RT, intraoperative RT (IORT), or intensity modulated RT (IMRT). Furthermore, severe toxicity was not observed. Short treatment time in relation to the short life expectancy gave patients more convenience and, finally, quality of life would be increased. Consequently, this could be regarded as an effective novel treatment modality for locally advanced, unresectable pancreas cancer. PTV would be a helpful prognostic factor for CK.

• Environmental and Resource Economics Review
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• v.20 no.3
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• pp.595-628
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• 2011

This study investigates the issues and suggests reform measures in applying CV methods to the Korea Development Institute's (KDI's) Preliminary Feasibility Test (PFT) of public projects. Most public projects on culture, science and environment evaluated under the PFT system belong to the category of "nonstandard" projects whose outputs are non-marketed, and CV is currently the main tool used for their benefit estimation. A careful discussion and investigation is recommended for the selection of target population, payment vehicle, and number of payment times. Operating expert reviews, focus group interviews, and pre-tests is highly recommended to reduce the potential bias involved in the CV studies. A single or double bounded dichotomous choice format is the most popular design of questionnaire, but we identify several undissolved issues in designing and implementing the format. Some other forms of inducing WTPs may still deserve our consideration. Various specifications of the WTP function need to be tried and tested based on their stability, in particular. Employing a nonparametric approach is also recommended. Treatments of 0 or negative WTPs and protest bids are shown to be the most serious issues that affect the estimation results significantly. We review diverse measures of handling those issues and summarize their advantages and shortcomings.

• Progress in Medical Physics
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• v.14 no.1
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• pp.8-14
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• 2003

The spinal cord dose is the one of the limiting factor for the radiation treatment of the head ＆ neck or the thorax region. It is not an easy task to maintain the spinal cord dose below tolerance and to keep the clinically acceptable dose to the PTV in this region. To overcome this problem, the spinal cord partial block technique (PBT) with the dynamic Multi-Leaf Collimator (dMLC) has been developed. This technique is an extension of the conventional treatment planning. In the beginning the beam directions are selected as same as the conventional treatment planning to encompass the PTV, then the partial block are designed to shield the spinal cord. The plan comparisons between the conventional therapy plan and the PTB plan were performed to evaluate the validity of this technique. The mean dose and the dose volume histogram (DVH) were used as the plan comparison indices. A series of quality assurance (QA) was performed to guarantee the reliable treatment. The QA consisted of the film dosimetry for the verification of the dose distribution and the point measurements. The PBT plan generated better results than the conventional treatment plan and it was proved to be useful for the H＆N region.

• Korean Journal of Remote Sensing
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• v.29 no.1
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• pp.11-20
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• 2013

Space-borne Synthetic Aperture Radar(SAR) has been one of the most effective tools for monitoring quantitative oceanographic physical parameters. The Doppler information recorded in single-channel SAR raw data can be useful in estimating moving velocity of water mass in ocean. The Doppler shift is caused by the relative motion between SAR sensor and the water mass of ocean surface. Thus, the moving velocity can be extracted by measuring the Doppler anomaly between extracted Doppler centroid and predicted Doppler centroid. The predicted Doppler centroid, defined as the Doppler centroid assuming that the target is not moving, is calculated based on the geometric parameters of a satellite, such as the satellite's orbit, look angle, and attitude with regard to the rotating Earth. While the estimated Doppler shift, corresponding to the actual Doppler centroid in the situation of real SAR data acquisition, can be extracted directly from raw SAR signal data, which usually calculated by applying the Average Cross Correlation Coefficient(ACCC). The moving velocity was further refined to obtain ocean surface current by subtracting the phase velocity of Bragg-resonant capillary waves. These methods were applied to Envisat ASAR raw data acquired in the East Sea, and the extracted ocean surface currents were compared with the current measured by HF-radar.