• Journal of Food Hygiene and Safety
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• v.13 no.3
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• pp.213-220
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• 1998

Bioconcentration factors of some carbamates BPMC, carbaryl and carbofuran were determined. The tested fishes were zebrafish (Brachydanio rerio) and red sword tail (Xiphophorus hellieri). The fishes were exposed to 0.05 ppm, 0.01 ppm, 0.50 ppm, one- hundredth concentration of 96-hrs $LC_{50}$ and one-thousandth concentration of 96-hrs LCso and test periods were 3, 5 and 8 days. Obtained results are summerized as follows: In the case of BPMC and carbaryl, BPMC and carbaryl concentration in zebrafish extract and BCF s of BPMC, carbaryl were lower than those of red sword tail, and increased as increasing test concentration. In the case of same experimental concentrations, BPMC concentration in zebrafish extract and $BCF_s$ of BPMC were decreased as prolonging test periods. In the case of same experimental periods, carbaryl concentration in zebrafish extract and BCF s of carbaryl were decreased as increasing test concentration, especially dropped at 0.50 ppm. Carbofuran did not bioaccumulate in zebrafish for test periods, in the case of red sword tail, it was impossible to calculate on $BCF_s$ data because test concentration of one-hundredth and one-thousandth of 96hrs $LC_{50}$ was under the detecting limit on GC. Test concentration of 0.05 and 0.10 ppm were the same tendency with BPMC and carbaryl. Determined depuration rate conatant were highest on carbofuran, and followed by carbaryl, and BPMC. It is suggested that low BCF of carbofuran is due to its relatively high water solubility and depuration rate, compared to BPMC and carbaryl. Therefore, carbofuran had no little bioconcentration effect on the aquatic ecosystem.

• Journal of dental hygiene science
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• v.11 no.5
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• pp.431-436
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• 2011

The aim of this study was to compare the effects of the short-term use of the desensitizing dentifrices marketed in Korea in vitro. Fifty human dentine specimens were wet ground with silicone carbide paper and etched with 6% citric acid for 90 seconds to allow complete opening of the dentinal tubule. Ten specimens from each group were brushed for 50 and 150 strokes with a V8 Cross Brushing Machine(Sabri Co., U. S. A). All the specimens were evaluated by SEM(${\times}3000$). The degree of occlusion of the dentinal tubules was quantified using an image analyzer. The results were analyzed by one-way ANOVA and Tukey's multiple comparisons using Window SPSS. The dentifrices containing nano-carbonate apatite, potassium nitrate and hydroxyapatite showed significantly higher occlusion effects than the other dentifrices after toothbrushing for 50 strokes(p<0.05). The Sensodyne freshmint$^{(R)}$dentifrice showed 34% fewer open tubular areas compared with the Sensodyne original$^{(R)}$dentifrice for 50 strokes. According to the short-term use of desensitizing dentifrices, the dentifrices containing nano-carbonate apatite, potassium nitrate and hydroxyapatite were most effective in occluding the dentinal tubules.

• Journal of Veterinary Clinics
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• v.27 no.3
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• pp.262-267
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• 2010

Magnesium ($Mg^{2+}$) is an essential co-factor for over 325 physiological and biochemical processes so that plays a central role of neuronal activity, cardiac excitability, neuromuscular transmission, muscular contraction, vasomotor tone, and blood pressure significantly related to physical performance. However, only limited information on blood ionized $Mg^{2+}$ ($iMg^{2+}$) regarding to physical exercise is available and the data from blood total $Mg^{2+}$ detection are inconsistent. This present study investigated the changes of blood $iMg^{2+}$ correlated with metabolic demands during acute high-intensive exhaustive physical exercise in rats. After exhausted swimming (3-4 hours), blood pH, glucose, $HCO_3{^-}$, oxygen and ionized $Ca^{2+}$ ($iCa^{2+}$) were significantly decreased, whereas lactate, carbon dioxide, $iMg^{2+}$, ionized $Na^+$ and ionized $K^+$ were significantly increased. During the exhausted swimming, the changes in $iMg^{2+}$ showed a significant negative correlation with changes in pH, glucose, $HCO_3^-$ and $iCa^{2+}$, however a significant negative correlation with changes in lactate and anionic gap. It is concluded that the acute high-intensive exhaustive physical exercise could produced hypermagnesemia, an increase in blood $iMg^{2+}$ via stimulation of $iMg^{2+}$ efflux following increase in intracellular $iMg^{2+}$ from muscle induced by metabolic and respiratory acidosis.

• Journal of Life Science
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• v.18 no.6
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• pp.826-831
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• 2008

The purpose of this study was to examine the effects of octacosanol and Taekwondo program on the fatigue substance, immunoglobulin after short term weight loss 21 male Taekwondo players. They were stay in a camp training together 6 days from same exercise and Octacosanol group and weight loss group is reduced over 5% weight loss by diet calorie restriction decrease gradually. Octacosanol intaked 2 times 20 mg after a meal. Control and weight loss group intaked placebo drug. The conclusions obtained from the above were as follow: Blood Fatigue Substance As lactate, The intra-group comparison decreased octacosanol group after loss weight. The between groups comparison, octacosanol group was superior to control and weight loss group. As lactate dehydrogenase, control and weight loss group increased after weight loss. As ammonia, The intra- group comparison decreased octacosanol group after loss weight. The between groups comparison, octacosanol group was superior to control and weight loss group. Immunoglobulin As IgA, IgG The intra-group comparison increased all group. As IgM, The were no significant differences between group. In conclusion, these results indicate that intake octacosanol after loss weight positive effects on the fatigue substance, Immunoglobulin for male Taekwondo players. Mter this study, We need to study about multilateral research for weight players.

• Journal of Life Science
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• v.18 no.12
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• pp.1739-1744
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• 2008

The purpose of this study was investigate the effects of short-term exercise and capsaicin supplementation on serum lipids, antioxidants and Akt contents in diabetic rats whose symptom was induced through the use of 50 mg/kg streptozotocin, 31 white rats were experimented. Rats in one exercise group and another exercise-capsaicin supplementation group exercised on a treadmill maintained by a 15-min run at $0^{\circ}$ inclination five times for a week during two weeks one week after the diabetes was induced. 10 mg of capsaicin per kilogram of weight was orally administered to rats in the capsaicin supplementation group after the diabetes was induced. The serum lipids were analyzed through the use of blood obtained from the incision of the abdomen, and antioxidants and Akt contents were analyzed through the use of livers to reach following conclusions. As for the serum lipids, TG significantly decreased in group DCE and HDL-C was higher than in other groups. ROS significantly decreased in all groups except for group D. CAT significantly increased in group DC, SOD was significantly high in groups DE and GSH was significantly high in all groups except for D. Akt contents significantly increased in group DC and p-Akt in group DE. As a result of this study, it has been found that short-term exercise and the capsaicin supplementation had a significantly effect on the serum lipids, antioxidants and Akt contents.

• Journal of Life Science
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• v.29 no.12
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• pp.1329-1336
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• 2019

Subventricular zone (SVZ) in the brain contains neural stem cells (NSCs) which self-renew and differentiate to neurons and glial cells during postnatal period and throughout adulthood. Since fate decision to either proliferation or differentiation has to respond to intracellular and extracellular conditions, many intrinsic and extrinsic factors are involved. Among them, mitochondria have been reported to participate in fate decision of NSCs. In our previous report, we showed that long-term treatment of a mitochondrial inhibitor rotenone greatly inhibited neurogenesis. In this study, we examined the effects of short-term treatment of rotenone on SVZ NSCs. We found that (1) even one-day treatment of rotenone significantly reduced neurogenesis and earlier time points seemed to be more sensitive to rotenone, (2) a number of Mash1+ transit amplifying cells was decreased by one-day treatment of rotenone, (3) short-term treatment of rotenone eliminated most of the differentiated Tuj1+ neurons and Olig2+ oligodendrocytes, while glial fibrillary acidic protein (GFAP)+ astrocytes were not affected, and (4) sulfiredoxin 1 (Srxn1) gene expression was increased after one-day treatment of rotenone, indicating activation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway. All these results confirm that functional mitochondria are necessary during differentiation to neurons or oligodendrocytes as well as maintenance of neurons after differentiation. Also, these data suggest that temporary exposure to mitochondrial inhibitor such as rotenone might have long-term effects on neurogenic potential of NSCs.

• Proceedings of the KOR-KST Conference
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• 1998.10a
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• pp.265-274
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• 1998

본 논문은 도로를 주행하는 차량의 지점속도에 대하여 단기간(short-term)으로 예측하는 네 가지의 모형들에 대한 개발 및 결과의 비교하고 평가했다. 사용된 기법들로는 다중회귀분석, 시계열분석(ARIMA), 인공 신경망, 칼만필터링 등이며, 모형의 구출을 위하여 다수의 독립변수 및 입력변수가 요구되는 다중회귀분석과 인공 신경망에서는 연속방정식에서 고려되는 변수들간의 단순상관계수 및 편상관계수의 계산을 통해서 입력변수가 설정이 되었으며, 시계열분석(ARIMA)과 칼만필터링 등 단일 입력 변수만을 요하는 모형에서는 바로 전 시간대와 현재시간대의간격동안 속도의 변화량을 입력변수로 설정하였다. 속도를 비롯해서 교통 데이터는 현장자료를 사용하였는데, 이는 서울의 한강 옆에 위치한 올림픽대로 중 한강대로에 위치한 검지기 3개를 통해서 천호동 방면으로 이동하는 교통류에 대해서 17시간 (00시~17시)동안 수집했다. 17시간 수집했는데 그중에 검지된 속도는 14km/h에서 98km/h까지 변하는 등, 수집된 자료에는 다양한 교통상태가 포함되어 있는데 이는 각 모형들의 정확한 예측력과 적응성을 평가하기 위함이었다. 각 모형은 예측하고자 하는 시점으로부터 1, 5, 10, 15분 후의 속도를 예측하는 것으로 총 4가지의 예측시간간격으로 각각 실험되었다. 결과는 전반적으로 신뢰성 있게 나왔으나 그중에서도 정확성면에서는 인공신경망과 칼만필터링이 우수했고 적응성면에서는 칼만필터리딩 탁월했다. 또한 1분 후의 속도를 예측하는 결과들은 모형들간에 거의 비슷한 정확도를 보여주었는데 이는 입력변수의 설정이 중요한 것임을 보여주는 것이라 판단된다. 있는 기법이다.적으로 세부적 차종분류로 접근한다.의 영향들을 고려함으로써 가로망 설계 과정에서 가로망의 상반된 역할인 이동성과 접근성의 비교가 가능한 보다 현실적인 가로망 설계 모형을 구축하고자 한다. 지금까지 소개된 가로망 설계모형들은 용량변화에 대한 설계변수의 형태에 따라 이산적 가로망 설계 모형과 연속적 가로망 설계모형으로 나뉘어지게 된다. 본 논문의 경우, 계산속도의 향상 측면에서는 연속적 가로망 설계 모형을 도입할 수 있지만, 이때 요구되는 도로용량이 이산적인 변수(차선 수)로 결정되어야만 신호제어 변수를 결정할 수 있기 때문에, 이산적 가로망 설계 모형이 사용된다. 하지만, 이산적 설계모형의 경우 조합최적화 문제이므로 정확한 최적해를 구하기 위해서는 상당한 시간이 소요되며, 경우에 따라서는 국부 최적해에 빠지게 된다. 이러한 문제를 극복하기 위해, 우선 이상적 모형의 근사화, 혹은 조합최적화문제를 위해 개발된 Simulated Annealing기법의 적용, 연속적 모형의 변수를 이산화하는 방법 등 다양한 모형들을 고려해 본 뒤, 적절한 모형을 적용할 것이다. 가로망 설계 모형에서 신호제어를 고려하기 위해서는 주어진 가로망에 대한 통행 배정과정에서 고려되는 통행시간을 링크통행시간과 교차로 지체시간을 동시에 고려해야 하는데, 이러한 문제의 해결을 위해서 최근 활발히 논의되고 있는 교차로에서의 신호제어에 대응하는 통행배정 모형을 도입하여 고려하고자 한다. 이를 위해서 지금까지 연구되어온 Global Solution Approach와 Iterative Approach를 비교, 검토한 뒤 모형에 보다 알맞은 방법을 선택한다. 차량의

• Proceedings of the KSCN Conference
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• 2003.11a
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• pp.1091-1092
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• 2003

당뇨병은 발병한 후에는 혈당조절을 위한 식사요법 실천이 평생에 걸쳐 지속적으로 이루어져야하는 질환이므로 식사요법에 대한 영양교육이 매우 중요하다. 본 연구에서는 지속적인 실습을 포함하는 소그룹 단위의 영양교육프로그램을 실시함으로써 식사요법 실천에 미치는 영향에 대해 알아보고자 하였다. 2003년 4월부터 7월까지 보건소에서 여성 당뇨병 환자 13명을 대상으로 혈당에 가장 영향을 미치는 당질식품의 적정섭취와 균형있고 규칙적인 식사를 강조한 쉬운 식사요법 교실의 형태로 연속 4주간, 2시간의 교육형태로 그룹인원을 5명 이하로 하여 실시하였다. 설문조사를 통하여 식사요법 장애 인자를 파악하였으며 교육 전후에 식사 섭취량, 혈당 허리둘레를 측정하여 비교하였다. 대상자의 평균 연령은 57.85 $\pm$ 9.55세, 유병 기간 6.38 $\pm$ 2.9년이었다 식사요법 교육을 받은 경험이 있는 환자는 15.4%이며 당뇨병 가족력을 가지고 있는 환자는 53.8%이었다. 당뇨병 발견 동기는 증상 .있었던 경우가 23.1%, 종합 진단시 발견된 경우 15.4%, 타 질환 치료시 알게된 경우 61.5%이었다. 저혈당 증세 및 대처방법을 알고 있는 환자는 53.8%이었다. 식사요법시 장애인자를 항목별로 질문하였을 때 가장 큰 장애는 주위에서 더 먹으라고 권유하는 것, 식사요법은 나에게 큰짐이 된다는 생각, 식사요법보다 일상생활에서 더 중요한 것이 많음이 53.8%로 답하였다. 교육 전후의 식사 섭취 량을 비교하였을 때 교육 전 에너지 섭취량은 1579.6 $\pm$ 355.8㎉ 교육 후 1505 $\pm$ 425.3㎉로서 70㎉정도 감소하였다. 교육 시 처방한 열량의 98.3%를 섭취하고 있었다. 당질섭취는 교육 전 257$\pm$60.6g 교육 후 214.8$\pm$56.1g로 감소하였고 단백질, 지질의 섭취는 교육전후에 큰 차이가 없었다. 총열량에 대한 3대 영양소의 섭취비율은 교육 전 57:23:20에서 교육 후 51:28:21로 당질비율은 감소하고 지질이나 단백질 섭취비율이 증가하였다. 교육전 후 식품군 별 섭취 량을 식품교환단위 수로 비교하였을 때 곡류군 섭취는 교육 전 5.87 $\pm$ 2.51에서 교육 후 5.38 $\pm$ 1.71로 교육후 당질 식품 섭취량이 감소하였으나 통계적으로 유의성은 나타나지 않았다. 교육 후 식품선택에서의 큰 변화는 과일류 중 토마토 섭취 비율 증가로 교육 전에는 총 과일 섭취량의 19.87%에서 교육 후에는 56.32%로 증가했다. 혈당은 교육후 42.8mg/㎗ 감소한 것으로 나타났으며 허리둘레는 교육 전 평균 83.8 $\pm$ 5.75에서 교육 후 82.33 $\pm$ 5.89cm로 약 1.5cm가량 감소하였다. 따라서 당질 식품 적정 섭취에 대한 실습 위주의 단기간 영양교육은 당뇨병 관리에 유익한 것으로 평가되었다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.6
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• pp.4040-4047
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• 2015

The purpose of this study was to analyze a change in Post-traumatic Stress Disorder (PTSD) level and the continuity of the effects in music therapy by applying short-term music therapy program in fire fighters with Post-traumatic Stress (PTS). Forty two fire fighters in 3 districts were randomly assigned to experimental group (21 subjects) and control group (21 subjects). Music therapy was applied in totally 10 sessions by two sessions (120 minutes) a day for 5 days. PTS level was measured immediately after the end of program, after 4 weeks, and after 12 weeks. As a result, PTS level has significantly decreased into $8.90{\pm}4.55$ from $26.52{\pm}2.32$ right after the music therapy program(p<0.05). And the effect was shown to be continued significantly up to after 4 weeks($11.95{\pm}4.57$) and after 12 weeks($13.76{\pm}5.62$)(p<0.05). As a result of research, it is considered that the music therapy is effective approach for reduction in PTS as for fire fighters who belong to the group with high risk of PTSD. Accordingly, the application of regular program for managing fire fighters' mental health is understood to likely to contribute to enhancing the field service competence.

• The Korean Journal of Mycology
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• v.38 no.1
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• pp.62-68
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• 2010

This study was performed to investigate the antagonistic properties of mushroom strains against Korean oak wilt pathogen (Raffaelea quercus-mongolicae) by assessing their predominance on potato dextrose agar plates after pairing culture. Among the total of 158 strains of mushroom tested, thirty-three strains showed no antagonistic activities against the pathogen in both the short term (6~7 days) and long term (27~31 days). Ninety-six strains of tested mushrooms had a weak or no long term antagonistic activity. The antagonistic activities of 29 strains were higher than those of other strains with the levels of $\geq$ R+ and $\geq$ R for short and long term, respectively. We found that these strains with antagonistic activities against R. quercus-mongolicae belong to the species of mushrooms living on different host plants such as conifers, oaks and other broad-leaved trees. In order to use the trees damaged by Korean oak wilt as a resource(bed-log) for cultivating mushrooms, seven strains of antagonist 29 strains were selected as follows; Laetiporus sulphureus KFRI 654, Laetiporus miniatus KFRI 914, Lentinula edodes KFRI 269 and 764, Pycnoporus coccineus KFRI 588, Schizophyllum commune KFRI 832 and Trametes versicolor KFRI 100.