• Childhood Kidney Diseases
• /
• v.18 no.2
• /
• pp.123-127
• /
• 2014

Erythema multiforme (EM) is an acute mucocutaneous disorder involving the skin, mouth, eyes, and genital organs. It is classified into EM minor and EM major according to the involvement of the mucosal membrane. Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) belong to EM major. Compared to EM minor, SJS presents with more severe and progressive symptoms, and has a higher mortality rate. Corticosteroids are used in the treatment of EM. We report three cases of EM (two cases of EM minor and one case of SJS) that developed during treatment with oral corticosteroid (deflazacort; $Calcort^{(R)}$) in children with nephrotic syndrome.

• Journal of Oral Medicine and Pain
• /
• v.38 no.1
• /
• pp.1-5
• /
• 2013

Erythema multiforme(EM), a blistering and ulcerative inflammatory disorder, affect skins or mucosa, and is thought to be triggered mainly by preceding infection, such as Herpes simplex virus, or exposure to drugs and medication, particular antibiotics or analgesics. Symptoms include typical cutaneous target lesions on skins and in case of oral manifestation, erosive and ulcerative lesions on lips, buccal mucosa, and tongue are known to occur, which needs differential diagnosis with other intraoral lesions. In this case, EM assumed that it is occurred by giving Trichomonas infection or Metronidazole in oral region is introduced with a review of diagnosis and treatment of EM.

• Journal of Oral Medicine and Pain
• /
• v.36 no.4
• /
• pp.207-213
• /
• 2011

Painful, ulcerative lesions of various systemic disease can affect the oral mucosa membrane at first. If you don't consider the skin lesion, followed or accompanied by oral mucosa, you are likely to fail in differential diagnosis. In this cases, we introduced erythema multiforme and Stevens-Johnson syndrome(SJS) patients with painful, ulcerative lesions on oral mucosa and skin. Also we review oral mucosal diseases come with the skin lesions.

• Journal of Oral Medicine and Pain
• /
• v.34 no.1
• /
• pp.55-62
• /
• 2009

In most cases, it is difficult to diagnose ulcerative diseases of the mouth, because they have many similar clinical appearance. For the diagnosis of oral ulcerative lesions, the clinician should check a detailed history of the patient and consider the relation with systemic diseases. In this case report, we introduced two patients with erythematous multiforme, phemphigus, lichenoid reaction and aphthous stomatitis as clinical diagnosis. The lesions were improved by medication.

• Neonatal Medicine
• /
• v.18 no.2
• /
• pp.391-394
• /
• 2011

Neonatal lupus erythematosus (NLE) is a rare disease characterized by typical clinical features and the transplacental passage of maternal autoantibodies, particularly anti-SSA/Ro. The major clinical manifestations are cutaneous lupus lesions, congenital heart block, hematological disorders, and hepatobiliary diseases. We report a case of NLE presenting with multiple round and oval target-like erythematous skin lesions and abnormal liver function, born to a clinically asymptomatic mother whose diagnosis was made retrospectively only after her newborn's diagnosis. Both the infant and the mother were positive for the anti-SSA/Ro and anti-SSB/La antibodies.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.29 no.3
• /
• pp.240-248
• /
• 2016

Objectives: The purpose of this study is to report the effectiveness of Sihochunggan-tang gagambang in two patients with erythema multiforme which ocurred repeatedly in stress condition.Methods: This case study was conducted in two erythema multiforme(EM) patients who have visited Korean Medicine Clinic. All two patients were treated with Sihochunggan-tang gagambang and acupuncture. VAS(Visual Analogue Scale) score was used to check the subjective change of skin symptoms and itching sense.Results & Conclusions: The VAS score were decreased compared to the initial visit in all two patients in our study. And most skin symptoms and itching sense of two patients were improved. As a result of examining VAS scores and photographs, Sihochunggan-tang gagambang can be effective on EM in two cases in our study.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.17 no.2
• /
• pp.153-158
• /
• 2004

Background and Objective: Erythema multiforme(EM) is related disorders of skin and mucous membranes which is typically associated with antecedent medications or infections. etc. EM is an erythematous maculopapular cutaneous eruption of variable form. However, the pathophysiology of the EM remains obscure. Treatment at present is symptomatic and supportive. There is no report on EM treated with oriental medical treatment. Methods: We conducted one patient with EM seen at Won-Kwang University Kwang-Ju Oriental Medical Hospital in 2004. We treated EM in a twenty-two years old man by a herbal medicine(Joa-Chang-Bang), a herbal medicine for external use, acupunture, moxa, COTDE-made cosmetics, and P-Tx(carbon). Conclusions. We had a significant results. So we report this case to estimate the efficiency of oriental medical treatment and management on EM.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.28 no.2
• /
• pp.75-84
• /
• 2015

Objectives : The purpose of this study is to report the oriental medical treatment on erythema multiforme caused by acute tonsillitis. Methods : Patient who has been ill Acute tonsillitis suffers from erythema, edema, pruritus, burning sensation of systemic skin. The patient was admitted to Dunsan oriental hospital for 7 days and was treated with oriental medicine(acupuncture, herbal-medicine, and vapor treatment). To evaluate the results of this treatment, the improvement of symptoms(erythema, pruritus, burning sensation) was identified by patient's subjective expression and in lesion-symptom improvement. Results : The symptoms caused by acute tonsillitis on total skin were improved. Conclusions : This study shows that the oriental medical treatment effects on the erythema multiforme caused by acute tonsillitis. Also, the public suggests that the correlation between the skin and tonsil.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.36 no.1
• /
• pp.124-131
• /
• 2023

Objectives : The aim of this study is to report the improvement of symptoms in patients with systemic erythema multiforme through Korean medicine treatment. Methods : We treated 51 years old male patient who diagnosed with erythema multiforme for 15 days with acupuncture, herbal medicine, pharmacopucture, cupping therapy and Hwangryunhaedok-tang wet dressing therapy. We used two herbal medicine; Hwabanhaedok-tang for first 10 days and Danggwieumja for another 5 days. Improvement of symptoms was evaluated by Visual Analogue Scale(VAS) and photography of lesions. Results : Most of the erythema disappeared, leaving only pigmentation. Subjective symptoms of patients such as itching, hot flash, dryness were decreased from VAS 7 to VAS 1-2. Conclusions : We found that Korean medicine treatment including herbal medicine, acupuncture was effective in improving systemic acute erythema multiforme.

• Journal of Oral Medicine and Pain
• /
• v.36 no.2
• /
• pp.99-105
• /
• 2011

The vermilion zone of the lips is mucocutaneous junction between the skin and the oral mucosa of lips. Diseases of the vermilion zone may be related to a local or systemic condition, and can be manifestation of a systemic disease. In this cases, we introduced patients with hemorrhagic, ulcerative lesions on the vermilion zone and reported plasma cell cheilitis and lesion of the vermilion zone related to Stevens-Johnson syndrome(SJS).