• Communications of the Korean Institute of Information Scientists and Engineers
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• v.16 no.12
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• pp.32-35
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• 1998

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2002.11a
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• pp.233-244
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• 2002

The purpose of this study is to assess the ability of balance control in moving surround using head mount device and force platform and to examine the clinical usefulness of COP parameters. Fifteen patients with stroke and healthy persons were participated. COP parameters were obtained as total path distance, frequency of anterior-posterior and medial-lateral component by FFT analysis, weight-spectrum analysis in the two different conditions; (1) in comfortable standing with opened or closed eyes, (2) in virtual moving surround delivered using HMD to four different moving pattern. In virtual moving surround setting, moving pattern was composed of close-far, superior-inferior tilting(pitch), right-left tilting(roll) and horizontal rotation(yaw) movement. In all parameters, the reliebility of COP analysis system was significantly high. Also, the construct validity compared between fifteen patients with stroke and normal persons was excellent in virtual moving surround condition(p

• The Korean Journal of Applied Statistics
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• v.35 no.1
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• pp.161-175
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• 2022

Oscillatory magnetic fields produced in the brain due to neuronal activity can be measured by the sensor. Magnetoencephalography (MEG) is a non-invasive technique to record such neuronal activity due to excellent temporal and fair amount of spatial resolution, which gives information about the brain's functional activity. Potential utilization of high spatial resolution in MEG is likely to provide information related to in-depth brain functioning and underlying factors responsible for changes in neuronal waves in some diseases under resting state or task state. This review is a comprehensive report to introduce statistical models from MEG data including graphical network modelling. It is also meaningful to note that statisticians should play an important role in the brain science field.

• Progress in Medical Physics
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• v.16 no.1
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• pp.32-38
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• 2005

Impaired processing of facial information is one of the broad ranges of cognitive deficits seen in patients with schizophrenia. The purpose of this study was to elucidate the differences in brain activities involved in the process of facial working memory between schizophrenic patients and healthy comparison subjects. Ten patients with schizophrenia were recruited along with matched healthy volunteers as a comparison group. Functional magnetic resonance imaging (fMRI) was used to assess cortical activities during the performance of a 1-back working memory paradigm using images of neutral faces as mnemonic content. The patient group performed the tasks with reduced accuracy. Group analysis revealed that left fusiform gyrus, right superior frontal gyrus, bilateral middle frontal gyri/insula, left middle temporal gyrus, precuneus and vermis of cerebellum and showed decreased cortical activities in the patient group. On the other hand, an increased level of activation in lateral prefrontal cortex and parietal lobule was observed from the patient group, all in the right hemisphere. A decreased level of activity in the left fusiform gyrus among the patient group implicates inefficient processing of facial information. An increased level of activation in prefrontal and parietal neural networks from the patient group confirms earlier findings on the impaired working memory of patients with schizophrenia.

• Journal of the Korean Society of Radiology
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• v.15 no.4
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• pp.507-518
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• 2021

Magnetic resonance imaging (MRI) is a key technology that has been seeing increasing use in studying the structural and functional innerworkings of the brain. Analyzing the variability of brain connectome through tractography analysis has been used to increase our understanding of disease pathology in humans. However, there lacks standardization of analysis methods for small animals such as mice, and lacks scientific consensus in regard to accurate preprocessing strategies and atlas-based neuroinformatics for images. In addition, it is difficult to acquire high resolution images for mice due to how significantly smaller a mouse brain is compared to that of humans. In this study, we present an Allen Mouse Brain Atlas-based image data analysis pipeline for structural connectivity analysis involving structural region segmentation using mouse brain structural images and diffusion tensor images. Each analysis method enabled the analysis of mouse brain image data using reliable software that has already been verified with human and mouse image data. In addition, the pipeline presented in this study is optimized for users to efficiently process data by organizing functions necessary for mouse tractography among complex analysis processes and various functions.

• Proceedings of the Korean Society for Cognitive Science Conference
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• 2002.05a
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• pp.208-210
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• 2002

신경과 의사들은 실제 임상에서 환자들에게 대뇌피질감각의 이상 여부를 알기 위해 손바닥에 숫자나 문자를 쓰게 하여 알아 맞추게 하는 검사를 시행한다. 손바닥에 쓰여진 문자나 숫자를 인식하기 위해서는 몇 가지 단계의 인지과정이 필요할 것으로 생각된다. 첫번째로 손바닥에 닿는 감각을 인지해야 하고, 다음 단계로 이 감각들을 시공간적으로 통합하는 과정이 필요할 것이고, 이러한 정보들을 유지하면서 마지막 단계로 우리 머리 속에 있는 문자와 일치시키는 과정이 필요할 것이다. 본 연구에서는 위와 같은 가설 아래 각각에 해당할 수 있는 뇌영역을 밝히기 위해 기능적 뇌자기공명영상을 이용하였다. 손바닥의 일차적 감각을 인지하는 데는 일차감각영역이 활성화 되었고, 이차감각영역의 활성은 감각들의 시공간적 통합과 관련될 것으로 생각되었으며, 이것들을 유지하는 것은 작업기억의 하부구조인 시공간 그림판과 관련되는 영역이며, 문자를 일치시키는 과정은 브로카영역 부근의 활성과 관련되는 것으로 생각되었다. 위의 가설에 대한 추가검증 및 실제로 일어나는 인지과정에 대한 추가적인 연구가 필요할 것이다.

• Proceedings of the KAIS Fall Conference
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• 2009.05a
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• pp.13-17
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• 2009

In this thesis, we made a sheet to improve the concentration of study. To demonstrate the improvement in the concentration of study, we obtained functional magnetic resonance imaging (fMRI), which has superior time resolution and measures brain noninvasively by using intrinsic contrast agent. As a result of Brainwave measurement, we could verify the blood flow's activate in the nearby frontal lobe related to memory process and noticeable ratio change in absolute alpha wave and beta wave after the analysis of Brainwave measurement. fMRI ascertains the physiological function of the brain and is being used to prevent the trouble medically that can be caused before and after the operation. For the visibility of cranial nerve network, many researches will be carried out to develope the product which is related to brain like concentration of study.

• Journal of the Korean Data and Information Science Society
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• v.20 no.3
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• pp.541-550
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• 2009

This research attempted to find out any implications for strategies to design and develop the connections between the activities of the brain function and the fields of English learning (dictation, word level, speaking, word memory, listening). Thus, in developing the brain based learning model for the English education, attempts need to be made to help learners to keep the whole brain toward learning. On this point, this study indicated the significant results for the exclusive brain location and the brainwaves on the each English learning field by the quantitative EEG analysis. The results of this study presented the guidelines for the balanced development of the left brain and the right brain to train the specific site of the brain connected to the English learning fields. In addition, whole brain training model is developed by the quantitative EEG data not by the theoretical learning methods focused on the right brain training.

• Journal of the Korean Society of Radiology
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• v.7 no.5
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• pp.305-311
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• 2013

This study involves an experiment using functional magnetic resonance imaging(fMRI) to delineate brain activation for execution functional performance. Participates to this experiment of the normal adult (man 4, woman 6) of 10 people, is not inserts the metal all closed phobia and 24.5 year-old average ages which the operating surgeon experience which are not they were. The subject for a functional MRI experiment word -color test prosecuting attorney subject rightly at magnetic pole presentation time of 30 first editions and after presenting, uses SPM 99 programs and the image realignment, after executing a standardization (nomalization), a difference which the signal burglar considers the timely order as lattice does, pixel each image will count there probably is, in order to examine rest and active crossroad dividing independence sample t-test (p<.05). Overlapped in this standard anatomic image and got a brain activation image from level of significance 95%. With functional MRI resultant execution function inside being relation, the prefrontal lobe, anterior cingulate gyrus, parietal lobe, orbitofrontal gyrus, temporal lobe, parietal lobe was activated. The execution function promotes a recovery major role from occupational therapy, understanding about the damage mechanism is important. When confirms the brain active area which accomplishes an execution function brain plasticity develops the cognitive therapeutic method which is effective increases usefully very, will be used.

• Korean Journal of Biological Psychiatry
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• v.28 no.2
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• pp.23-35
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• 2021

Fear conditioning and extinction, which are adaptive processes to learn and avoid potential threats, have essential roles in the pathophysiology of anxiety disorders. Experimental fear conditioning and extinction have been used to identify the mechanism of fear and anxiety in humans. However, the brain-based mechanisms of fear conditioning and extinction are yet to be established. In the current review, we summarized the results of neuroimaging studies that examined the brain changes-functional activity and structures-regarding fear conditioning or extinction in healthy individuals. The functional activity of the amygdala, insula, anterior cingulate gyrus, ventromedial prefrontal cortex, and hippocampus changed dynamically with both fear conditioning and extinction. This review may provide an up-to-date summary that may broaden our understanding of pathophysiological mechanisms of anxiety disorder. In addition, the brain regions that are involved in the fear conditioning and extinction may be considered as potential treatment targets in the future studies.