• Applied Biological Chemistry
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• v.49 no.3
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• pp.254-258
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• 2006

Vitellogenin has been known as a potent biomarker protein for the estrogenic activity in fish exposed to endocrine disruptors. In this study, a piezoelectric immunosensor making use of an anticarp vitellogenin antibody and an AT-cut quartz crystal microbalance as the biological component and transducer was prepared, followed by its application to the analysis of carp vitellogenin as follows. Antibody immobilization was conducted by chemisorption of a thiolated antibody with a heterobifunctional thiolation cross-linker, sulfosuccinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate. The reaction buffer for the immunosensor system was optimized as 0.1 M sodium phosphate (pH 7.4). Concentration-dependent sensor responses were obtained in the vitellogenin concentrations ranging from 0.4864 to 486.4000 nM, with a linear correlation between vitellogenin concentration and frequency shift in double-logarithmic scale. The limit of detection of the immunosensor for carp vitellogenin was presumed as 0.4864 nM.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.87-87
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• 2018

지난 30년간 한반도의 연평균 기온은 $1.2^{\circ}C$ 상승하여, 전세계 100년간 평균 기온 상승 $0.74^{\circ}C$에 비해 그 상승폭이 크게 증가하였다. IPCC 5차 평가보고서(2013년)의 RCP 시나리오에 따르면, 4차 평가보고서(2007년)의 SRES 시나리오에서 보다 우리나라의 기후변화 영향이 크게 증가될 것으로 예상하고 있으며, 2050년 연평균기온의 변화가 기존 $2.0^{\circ}C$에서 $3.2^{\circ}C$로, 강수량은 기존 11.5%에서 15.6%대로 증가할 것으로 전망하고 있다. 우리나라의 최근 10년간 발생한 자연재난을 살펴보면 호우, 태풍에 의한 피해가 가장 크게 나타났고, 대설, 강풍에 의한 피해가 뒤를 이었으며, 기후변화의 영향으로 재난 재해의 형태는 점차 대형화 다양화 되어가고 있다. 이러한 기후변화에 대비하여 효율적인 재난 대응 및 대책수립을 위해 재난 위험도 평가의 필요성이 증대되고 있으며 국내의 다양한 부처에서 연구를 수행하고 있다. 그러나 재난 위험도 평가체계 및 방법론이 각 연구별로 다원화되어 있고, 실무적용 또한 미흡한 실정이다. 따라서 본 연구에서는 UNISDR 등 국제기구에서 제시하는 위험도 평가방법론을 기반으로 우리나라에 적용 가능한 위험도 평가 방법론을 정립하고, 홍수, 태풍, 대설, 가뭄 등에 대한 재난 위험도 평가 기법을 개발하였다. 또한 실제 피해 통계와 평가 결과에 대한 비교 및 적정성 분석을 통해 우리나라 실정에 맞는 최적의 위험도 평가 체계 및 방법론을 구축하고자 하였다. 본 연구를 통해 위해성, 노출성, 취약성 및 저감능력 지표로 구성된 재난 위험도 평가 기법을 개발하였고, 재난 유형별 지역별 10단계, 5등급의 위험도 평가 결과를 도출하였다. 본 연구에서는 홍수, 태풍, 대설, 가뭄 등 6개 자연재난 유형에 대한 위험도 평가 지표를 개발하였으며, 향후, 국가 및 지역 재난안전관리계획에 자연재난 위험도 평가 결과 활용을 위해 후속 연구를 추진 중에 있다.

• Journal of Climate Change Research
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• v.1 no.1
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• pp.21-30
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• 2010

In this study, vulnerability of water resources to climate change was assessed in terms of flood, drought and water management. Criteria and indicators were employed for assessing the vulnerability. The criteria used to assess the vulnerability was sensitivity of the study area, the exposure to climate and the adaptability to climate change. These criteria were quantified and standardized using corresponding indicators. Vulnerability of water resources to climate change is assessed to be generally increasing over time. The appropriate watershed scales are the large drainage basin for national level vulnerability assessment and the small drainage basin for local one.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.105-105
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• 2023

최근 기후변화로 인해 매년 집중호우 및 태풍으로 인한 침수피해가 증가하고 있다. 현재 국내에서는 이러한 피해를 줄이기 위해 구조적 대책뿐만 아니라 치수사업의 의사결정을 지원할 수 있는 비구조적 대책들이 대두되고 있다. 비구조적 대책으로는 재해예방사업 등에서 투자우선순위를 결정할 수 있는 다차원법, 홍수취약성지수 등과 같은 정량적, 정성적 홍수위험도 평가가 대표적이다. 하지만 기존 시군구별 홍수위험도 평가는 빈도별 홍수위험지도의 침수면적을 반영하지 않았었다. 따라서 본 연구에서는 서울특별시를 대상으로 빈도별(50, 80, 100 및 200년) 설계홍수량에 따른 홍수위험지도를 작성하고 IBA(Indicator Based Assessment) 방법을 활용한 홍수위험도 평가를 실시하였다. 홍수위험지수는 4가지 항목(Hazard, Exposure, Vulnerability 및 Capacity)과 8개의 세부지표로 구성하였다. 분석결과, 송파구와 성동구는 100년 빈도, 용산구와 강남구는 80년 빈도와 100년 빈도에서 홍수위험지수의 순위 변동이 관측되었다. 순위 변동이 발생한 주요 원인으로는 홍수위험도 평가에 반영된 Exposure 및 Vulnerability 항목에 포함된 세부지표별 지수가 시군구 내 빈도별 침수면적이 변화함에 따라 증가 혹은 감소했기 때문이었다. 본 연구를 활용하면 빈도별 침수면적 변화에 따른 시군구별 홍수위험도를 파악할 수 있으며, 그에 따른 예방책 또한 마련할 수 있을 것이다. 그리고 공간분석을 통해 도출된 통계지도를 활용하여 홍수위험에 직접적으로 노출된 건물 및 인구 밀집지역을 파악하고, 해당 지역을 대상으로 치수사업을 전개할 수 있을 것으로 판단된다.

• Journal of the Korean Society of Radiology
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• v.17 no.4
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• pp.565-572
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• 2023

This study was conducted to analyze the status radiological imaging examinations assessment in Korea medical institutions conducted in the public sector and suggest a direction for improvement. Among the assessment of medical institutions, the main assessment related to radiographic imaging examinations are the certification evaluation of medical institutions and the adequacy assessment of radiographic imaging examinations. The certification evaluation of medical institutions evaluates the image inspection operation process, provision of accurate results, and compliance with safety management procedures. In the assessment of adequacy of radiographic imaging examinations, structural indicators related to manpower and equipment, patient evaluation implementation rate, and exposure reduction programs were included. However, for safer and higher-quality radiological imaging examinations, it is necessary to increase the participation rate of medical institutions in certification evaluations. In addition, it is necessary to improve the manpower indicator, and incentive payments can be considered to induce quality improvement of medical institutions in the future. Integrated management of radiation exposure at the national level should also be carried out simultaneously.

• Journal of Marine Life Science
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• v.2 no.1
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• pp.34-38
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• 2017

FK506BP (FK506 binding protein 12) is a small peptide with a single FK506BP domain. It is involved in suppression of immune response, oxidative stress and inflammation. The purpose of this study was to investigate the gene expression of FK506BP in red seabream (Pagrus major) exposure to low water temperature (8℃, 33 psu) and low salinity (20℃, 10 psu). Results showed that, the expression of FK506BP was significantly increased in the experiment groups, such as low water temperature (8℃, 33 psu), and low salinity (20℃, 10 psu). These results suggest that FK506BP was played roles in biomarker gene on the environmental stress such as water temperature and salinity.

• Journal of Marine Life Science
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• v.2 no.2
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• pp.70-74
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• 2017

Interleukin-1 (IL-1) is one of the proinflammatory cytokines, after IL-1 binds to IL-1RI, IL-1RacP (interleukin-1 receptor accessory protein) joins with IL-1/IL-1RI to form a complex, and leading to cell activation. IL-1RAcP is involved in immune response, stress and apoptosis. The purpose of this study was to investigate the gene expression of IL-1RAcP in red seabream (Pagrus major) exposure to low water temperature (8℃, 33 psu) and low salinity (20℃, 10 psu). Results showed that, the expression of IL-1RAcP was significantly increased in the experiment groups, such as low water temperature (8℃, 33 psu), and low salinity (20℃, 10 psu). These results suggest that IL-1RAcP was played roles in biomarker gene on the environmental stress such as low water temperature and low salinity.

• Journal of Aquaculture
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• v.21 no.2
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• pp.111-122
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• 2008

This study was conducted to assess the usefulness of the temperature characteristics of the tidal flat sediments during low tide as a environmental factor, and burrowing behaviour, fatness, total hemocyte counts(THCs) and differential hemocyte counts(DHCs) of hard clam Meretrix lusoria as biological activity indices for the management of hard clam farms located in Taean(Chungnam province) and Gimje(Jeonbuk province) tidal flat in Korea. Temperature ranges of the sediment at 1cm depth during spring(March to May) and summer(June to August) in Taean(where the exposure time was about $5.5{\sim}6$ hours during low tide) were $8.7{\sim}26.8^{\circ}C\;and\;27.6{\sim}32.8^{\circ}C$, respectively. Even though there was no significant difference(P>0.05), temperatures of the surface sediment where submerged with remained seawater were generally higher than that of uncovered with seawater. Burrowing depths of normally digged hard clams were 0.9{\sim}3.6cm from March to October, 2002. In the field experiment performed at Taean farming ground covered with seawater, burrowing times of the clams under natural water temperatures were $41.6{\pm}10minutes$ in February and $5.4{\pm}1.3minutes$ in August, respectively, and these were influenced by water temperatures. Fatness of hard clams began to decrease from May(at Taean tidal flat) and June(at Gimje tidal flat), showed the lowest level in August and increased again from September. Total hemocytes counts in the hemolymph of the hard clams were decreased to the lowest level in July($24.7{\times}10^4cells/mL$, at Taean tidal flat) and August($28.2{\times}10^4cells/mL$, at Gimje tidal flat), and significantly increased again from September(at Taean tidal flat, P<0.01) and October(at Gimje tidal flat, P<0.001), respectively. We observed three types of hemocytes from the hemolymph of hard clams according to whether hemocytes retain the granules or not and the size of the granules. As a results, we could found that periodical monitoring of the sediment temperatures, clam burrowing behaviour and hemocyte parameters were very helpful for the management of hard clam farming.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.6 no.1
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• pp.77-87
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• 1996

In order to compare the difference of the measurement of delta aminolevulinic acid(${\delta}$-ALA) in urine between HPLC method(HALA) and colorimetric method(CALA), and also to provide useful information for the new diagnostic criteria of ${\delta}$-ALA in urine in lead poisoning, if at all possible in the future, authors studied 234 male lead workers who were selected from 7 storage battery factories, 3 secondary smelting industries, and 2 litharge making industries. Study subjects were selected on the basis of blood Zinc protoporphyrin(ZPP) level from low to high concentration to cover wide range of lead exposure. Study variables for this study were ${\delta}$-ALA measured by two different methods, blood lead(PbB), and blood ZPP. The results were as follows: 1. There was very high correlation between ${\delta}$-ALA measured by two method(r = 0.989 : HALA = -0.8194 + 0.8110 ${\times}$ CALA), but the value of CALA was measured about 2mg/L greater than HALA. 2. While the correlations of ${\delta}$-ALA by two method with blood lead and blood ZPP were 0.46 and 0.37 respectively, they were increased to 0.63 and 0.57 if ${\delta}$-ALA values were log-transformed. 3. Simple linear regression of ${\delta}$-ALA measured by two method on ZPP were as follows: CALA = 2.0421 + 0.0341 ${\times}$ ZPP ($R^2=0.1385$ p = 0.0001) HALA = 0.8006 + 0.0280 ${\times}$ ZPP ($R^2=0.1389$ p = 0.0001) 4. Simple linear regression of ${\delta}$-ALA measured by two method on PbB were as follows: CALA = - 0.4134 + 0.1545 ${\times}$ PbB ($R^2=0.2085$ p = 0.0001) HALA = -1.2893 + 0.1287 PbB ($R^2=0.2154$ p = 0.0001), 5. Simple linear regression of log-transformed ${\delta}$-ALA by two method on ZPP and PbB were as follows: logHALA = 0.3078 + 0.0060 ZPP ($R^2=0.3329$ p = 0.0001) logCALA = 1.0189 + 0.0044 ZPP ($R^2=0.3290$ p = 0.0001) logHALA = -0.0221 + 0.0246 PbB ($R^2=0.4046$ p = 0.0001) logCALA = 0.7662 + 0.0184 PbB ($R^2=0.4108$ p = 0.0001) 6. The cumulative percent of colorimetric method to detect lead workers whose value of PbS and ZPP were over screening level such as $40{\mu}/dl$ and $100{\mu}/dl$ respectively was higher than HPLC method if cut-off level of ${\delta}$-ALA for screening of lead poisoning was 5 mg/L. But if cut-off level of ${\delta}$-ALA measured by HPLC was reduced to 3 mg/L which is compatible to 5 mg/L of ${\delta}$-ALA measured by colorimetric method, there were good agreement between two methods and showed dose-response relationship with other lead exposure indices such as PbB and ZPP.

• Journal of the Korean Institute of Landscape Architecture
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• v.38 no.3
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• pp.33-40
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• 2010

Many trails have been built and utilized in each sub-basin of Apsan Park. This study focused on the conditions and the present flora of several overused trails within three basins called Kun-Gol, Anjiroung-Gol, and Meaja-Gol in Apsan Park. There are two purposes for this study. The first is to make a plan for restoration by classifying the type of damage to these overused trails. The second is to provide preliminary data for reestablishing a more pleasant urban nature park. As a result of the survey, the average length of these trails is 9.0km and mean width is 2.0 to 2.6m. 2,108m of the sections studied(23.4% of the total) had exposed root, 3,199m of the sections studied (35.5% of the total) had exposed rock, 3,270m of the sections studied(36.6% of the total) displayed damaged pathways, and 4,841m of the sections studied (53.8% of the total) had higher soil hardness. Eighty-three areas of deterioration were found and there has been extensive property destruction. As an indication of human disturbances, the Naturalization Index and Urbanization Index appeared as: Kun-Gol, 7.0%, 5.5%; Anjiroung-Gol, 8.3%, 4.5%; Meaja-Gol 8.6%, 6.2%; in total, 7.8%, 8.3%. As a method of checking the level and extent of the damage process, an impact rating classification was used at each point on the trails. Kun-Gol had the highest rating and Anjiroung-Gol had the lowest rating in impact rating classification. With the impact rating classification, it was found that each trail would continue to worsen, meaning that roots and rocks are more likely to be further exposed and the trail width will continue to widen through overuse. An actual plan for reparations and restoration of the trails is needed through further study.