• The Journal of the Korea institute of electronic communication sciences
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• v.18 no.6
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• pp.1363-1370
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• 2023

Globally, the elderly population is increasing, making the primary concern of modern society the healthy aging and welfare and medical facilities for the elderly. However, many seniors experience cognitive decline due to aging, making cognitive activities crucial for them. In this context, a study has developed a cognitive activity support system for the elderly using the metaverse. To achieve this, the characteristics and needs of the elderly were analyzed to design an interface in the metaverse that they can easily use. Additionally, the type and difficulty of cognitive activities were adjusted to engage seniors in a captivating manner. Experimental results showed that the proposed system effectively enhances the cognitive abilities of the elderly. Thus, the personalized metaverse-based cognitive activity support system proposed in this study can be a valuable tool for improving the cognitive abilities of the elderly.

• Journal of Life Science
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• v.25 no.6
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• pp.724-731
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• 2015

Mesenchymal stem cells (MSCs) are characterized by their multipotency capacity, which allows them to differentiate into diverse cell types (bone, cartilage, fat, tendon, and neuron-like cells) and secrete a variety of trophic factors (ANG, FGF-2, HGF, IGF-1, PIGF, SDF-1α, TGF-β, and VEGF). MSCs can be easily isolated from human bone-marrow, fat, and umbilical-cord tissues. These features indicate that MSCs might be of use in stem-cell therapy. However, MSCs undergo cellular senescence during long-term expansion, and this is accompanied by functional declines in stem-cell potency. In the human body, because of their senescence and declines in their microenvironmental niches stem cells fail to maintain tissue homeostasis, and as a result, senescent cells accumulate in tissues. This can lead to age-related diseases, including degenerative disorders and cancers. Recent studies suggest that the number of histone modifications to stem cells’ genomes and aberrant alterations to their DNA methylation increase as stem cells progress into senescence. These epigenetic alterations have been partly reversed with treatments in which DNA methyltransferase (DNMT) inhibitors or histone deacetylase (HDAC) inhibitors are introduced into replicative senescent-MSCs. This review focuses on epigenetic alteration in replicative senescent-MSCs and explains how epigenetic modifications are widely associated with stem-cell senescences such as differentiation, proliferation, migration, calcium signaling, and apoptosis.

• Journal of the Korean Society of Food Science and Nutrition
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• v.41 no.9
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• pp.1253-1258
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• 2012

In the present study, we investigated the effects of Rubus coreanus Miquel (RCM) on memory ability of senescence-accelerated mice (SAM). Prone 8 strains of SAM mice (SAMP8), which is a useful animal for investigating the mechanism of brain aging and senile dementia, were fed a diet containing 100 mg/kg body weight/day of RCM for 8 weeks. Memory ability of mice was examined by using passive avoidance test and Morris water maze test. SAMP8 mice showed remarkable memory impairment compared with senescence-resistant 1 strains of SAM (SAMR1). RCM significantly improved memory ability of SAMP8 mice. In addition, acetylcholineasterase activities decreased in the brain of SAMP8 mice treated with RCM. Taken together, these results suggest that RCM may act as an acetylcholineasterase inhibitor, thereby improving senescence-related memory impairment.

• 한국사회정책
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• v.23 no.2
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• pp.173-200
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• 2016

This study has two objectives. First, this study examines subjective well-being among elders that operationalize life satisfaction and aging anxiety, guided by life-course perspective. Second, it examines the relationship between subjective well-being and age-friendly environment factor structure among age-cohort groups. This study employs the stratified sampling method from 4,000 Seoul citizens. Main findings from the multivariate regression analyses include: (1) as age increases, aging anxiety levels appeared to be higher, while decreasing the life satisfaction. (2) a substantially larger variance of life satisfaction and aging anxiety was accounted for by demographic variables and age-friendly environments across age-cohort groups. (3) the influence of age-friendly environment factors such as neighborhood problems, accessibility to social activities, social services and parks on subjective well-being was different across age-cohort groups. This study discusses the policy and practical implications of the results.

• Journal of Digital Convergence
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• v.18 no.12
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• pp.343-351
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• 2020

The present study investigated the related variables of cognitive function, subjective cognitive decline and cognitive training effects. The cognitive training was composed of mete-cognitive education and cognitive task performing. Twenty older adults attended for 14 weeks and were tested before and after the training. Results show that their cognitive level was related with age, self-esteem and personality traits. And subjective cognitive decline was related depression, anxiety, personality traits, self-efficacy, self-esteem and subjective age, but it does not reflect objective cognitive impairments. Their cognitive test scores were enhanced after training in MMSE, memory and executive function, and enhanced scores were related with age, subjective cognitive decline, anxiety, self-efficacy, self-esteem, subjective age and personality traits. Findings suggest one's personality and psychological state need to be considered for the effects of cognitive training.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.7
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• pp.3358-3367
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• 2013

This study was conducted to examine the effects of the elderly patient's simulation experience on attitudes toward elderly and elderly patients, and empathy of elderly patients among nursing students. Study results showed that elderly patient's simulation experience did not have significant effects on attitudes toward elderly or elderly patients, whereas it had significant effect on enhancing the empathy on elderly patients. The subjects of experimental group indicated that the factors decreasing the effect of intervention are single event of experience, raising aging anxiety, lack of the reality of simulation clothing, and risk of accident during simulation experience, etc. In order to maximize the positive effects of the elderly patient's simulation program, it is necessary to find a way to improve those limiting factors identified from this study, and to continue to work on positive effects of elderly simulation applied for their curriculum.

• Proceedings of the Korea Contents Association Conference
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• 2006.11a
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• pp.156-159
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• 2006

The aging of population is a social phenomenon commonly observed in advanced countries. It causes various problems. Thus the aged problem must be approached from quality of life, which the elderly pursue instinctively regardless of their life cycle, and the utilization of their spare time or leisure hours. However, there have been research reports that, if the elderly participate in voluntary and active meaningful leisure, they can achieve successful adaptation to their aging and the life in their old age. In particular, we need to give our attention to the fact that, compared to other leisure activities, recreational sports make significant contributions to successful aging. When the aged participate in active leisure and recreational sports regularly, their satisfaction with spare time is enhanced and their loneliness is relieved, which resultantly brings high life satisfaction. This suggests that recreational sports activities enable the aged to achieve successful aging and contribute to the solution of the aged problem. In order to promote physical activity for aging population, we must utilize MINIMAX strategies.

• 한국노년학
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• v.32 no.3
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• pp.801-817
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• 2012

This study focused on the relationship between elderly's participation in lifelong education(participation availability, participating fields) and ego integrity. To verify the correlation of two variables, mediating model structured by life satisfaction was used. The data was Seoul Welfare Panel Data made by Seoul Welfare Foundation in 2010 and the total subject was 1,862 elderly aged over 60. When it comes to research methods, structured equation analysis for verifying the mediating effect was practiced. The findings are as follows: First, life satisfaction did function as partial mediator on relationship between elderly's participation in lifelong education and ego integrity. Second, elderly's life satisfaction increased as participating in field of language, not in field of culture and art. Ego integrity of elderly was increased as participating in field of culture and art, not in field of self-improvement and hobby. This study indicates theoretical and practical interventions to promote elderly's lifelong education based on the conclusion elderly's lifelong education participation in the aging society has positive effects on life satisfaction and ego integrity are meaningful for successful aging.

• Industry Promotion Research
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• v.9 no.2
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• pp.115-125
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• 2024

The increase in the elderly population and growing interest in skin beauty, alongside specialized scientific examination of natural substances, have led to a rise in the utilization of natural materials. This paper investigates the types of natural substances, the functionality of extracts, and extraction technologies based on the literature that utilizes natural ingredients to mitigate skin aging. To directly assess the impact of functional materials derived from natural products on skin aging mitigation, the functionality of the extracts was determined based on their ability to synthesize Procollagen and reduce MMP-1. Each natural product is categorized into plants, herbal medicines, and microalgae in the literature utilizing the above evaluation methods. This paper describes the extraction technologies for securing functional materials from each ingredient and the main outcomes, providing trends in research on extraction technologies for functional materials aimed at alleviating skin aging

• The Journal of Korean society of community based occupational therapy
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• v.6 no.1
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• pp.25-32
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• 2016

Purpose : This study attempted to observe the correlation between the activity levels and interpersonal relationships of elderly people. Method : This study implemented the Relationship Change Scale (RCS) and the Korean Activity Card Sort (K-ACS) on elderly people who use community welfare centers in the Busan and Ulsan areas from May 28, 2015 to August 26, 2015. Results : Total ACS scores and sensitivity showed a high correlation with .326. Next, instrumental activities of daily living and sensitivity showed a high correlation of .287, and instrumental activities of daily living and sense of satisfaction showed a high correlation of .277. However, social activities showed no correlation with the subcategories of interpersonal relationships. Conclusion : People who adequately carry out their roles in daily living and enjoy leisure activities showed high scores in interpersonal relationship satisfaction, understandability, sensitivity, and openness. This shows that it is necessary for elderly people to have interest in successful aging such as participation in activities that exceed welfare through simple medical support or interpersonal relationships and in demands related to the quality of life.