• Clinical and Experimental Pediatrics
• /
• v.49 no.7
• /
• pp.805-809
• /
• 2006

The incidence of endobronchial tumor in the pediatric period is very rare and the symptoms are very close to those of respiratory tract infection. Diagnosis can be delayed because of low clinical suspicion and the many ways in which these tumors can present. We report the first case, in Korea, of a pulmonary carcinoid tumor that presented with recurrent pneumonia at the same location in adolescence. Treatment is surgical and geared towards complete resection while sparing healthy lung parenchyma. Long-term and careful follow up is recommended to detect local and distant metastasis.

• Proceedings of the KOR-BRONCHOESO Conference
• /
• 1987.05a
• /
• pp.22.1-22
• /
• 1987

인후부, 하인두부 및 경부 등에 종양감각(lump sensation)등의 이상감각을 호소하는 globus 증후군은 Hippocrates가 처음 기술한 이래 많은 저자들에 의해 여러 가지 다양한 원인들이 기술되어 왔지만 아직 뚜렷한 병인이 밝혀지지 않은 상태로 기질적 원인에 대한 다각적인 연구가 진행중이다. 이에 저자들은 1986년 7월부터 1987년 2월까지 연세대학교 의과대학 이비인후과학 교실을 방문한 85명의 globus 증후 환자를 대상으로 전향적 연구를 시행 다음과 같은 결과를 얻었다. 1) 주증상은 무언가 걸린듯한 느낌이 가장 많았고(40.8%), 기타 점액객출 및 종양감각이 있었으며, 증상부위는 하인두부(26.8%) 및 윤상연골부(28.0%)가 많았고. 증상 유발인자로는 피로 및 신경과민증이 동반된 기질적 병변으로는 비후성 설편도염 및 인두염이 가장 많았다. 2) 비데오-식도조영술 검사상 27명(31.8%)에서 윤상인두근 이상수축이 있었으며 기타 식도복(3명), 식도점막이상(1명)등이 있었고 윤상인두근 이상수축이 있었던 환자군과 없었던 환자군 사이에 주증상, 증상부위, 동반증상, 기질적 병변 및 치료경과에는 차이가 없었으며 50% 이상의 수축을 보인 3명의 환자에서 내시경 검사상 이상소견은 관찰되지 않았다. 3) 치료는 특별한 기질적 병변이 없는 한 자세한 설명을 통한 치유의 확신감을 주고 필요에 따라 진정제, 제산제 및 cimetidine을 투여한 결과 65.3%에서 증상의 완전소실 및 현저한 호전이 있었고, 24.5%에서는 어느 전도의 호전이 있었으며, 10.2%에서는 증상의 호전이 없었다.

• Journal of the Korean Arthroscopy Society
• /
• v.4 no.2
• /
• pp.159-165
• /
• 2000

Purpose : Endoscopic carpal tunnel release technique was developed and has being used to decrease postoperative morbidity and complications. The purpose of this study was to evaluate the clinical results and clinical usefulness of endoscopic carpal tunnel release using single portal technique. Methods and Materials : 18 carpal tunnel syndrome patients who were diagnosed by means of clinical symptoms, physical examination, and electrodiagnostic study had endoscopic carpal tunnel release using single portal technique with about 1 cm oblique wrist incision on 30 hands. And then they were followed-up and reviewed in the same way. Late results of operation were analysed by grading system according to patient's own assessments of relief of symptoms at the final fellow-up. The follow-up period ranged 6 to 13 months from surgery. Results : There were postoperative improvements with respect to clinical symptoms, physical examination, and electrodiagnostic study. 23 of 30 hands$(76.7\%)$ had complete resolution of symptoms. 27 hands$(90\%)$ were able to return to normal activities and work within 6 weeks, and 30 hands$(100\%)$ returned within 8 weeks. In grip strength study, 29 hands$(96.6\%)$ regained preoperative strength in 6 months. 12 of 22 hands$(55\%)$ had improvement with respect to thenar atrophy within 6 months. Late results were as follows . 23 hands$(76.7\%)$ was graded as excellent, 6 hands$(20\%)$ graded as good and 1 hand$(3.3\%)$ graded as fair, and there was no poor result. Conclusion : We think that endoscopic carpal tunnel release with single portal technique is technically safe and simple, if the surgeon takes step to stay within the safety zone based on local anatomy and selects an appropriate patient and that endoscopic carpal tunnel release does have advantages over open release. We agree that the surgeon must be prepared to perform an open technique, if technical difficulties arise, difficulty in introducing the device into the carpal tunnel is encountered, or the transverse fibers of the transverse carpal ligaments are not clearly seen.

• Journal of the Korean Arthroscopy Society
• /
• v.10 no.2
• /
• pp.165-172
• /
• 2006

Purpose: The purpose of this study is to evaluate the effects of intratunnel fixation in the tibial side on the arthroscopic ACL reconstruction with quadruple hamstring tendon at the second look arthroscopy. Materials and Method: From Dec 1999 to May 2005, we arthroscopically reexamined 32 cases who had been done arthroscopic ACL reconstruction with quadruple hamstring tendons. Hamstring tendons of all cases were fixed at femoral side with RigidfixTM. At the tibial side hamstring tendons were fixed only Post-tie (Group I) or Post-tie combined with IntrafixTM (Group II). At the time of second look arthroscopy mean age of cases was 30 years and mean duration for second look arthroscopy was 21.3 months. We analyzed the results with IKDC score, KT-1000 arthrometer under anesthesia, Telos stress radiography, tibial tunnel widening on the radiography and second look arthroscopic findings. Results: Group II had more superior than group I at side to side differences with KT-1000 and Telos stress radiograph, IKDC score, but the differences were insignificant. At arthroscopic evaluation, Group ll also had more superior than group I at graft tension and graft appearance, graft synovialization, but the differences were insignificant. Tibial tunnel widening in the knee AP radiograph was 2.3 mm in Group I and 1.7 mm in Group II and the difference was significant. (P=0.042) Conclusions: Additional procedure of tibial intratunnel fixation in arthroscopic ACL reconstruction with autogenous hamstring tendon significantly prohibited from tibial tunnel widening but clinical results, radiologic joint stability, findings in second look arthroscopy were insignificantly different. We concluded that Post-tie itself induced satisfactory clinical results, joint stability and graft maturation and that tibial tunnel widening did not affect the results.

• Journal of Veterinary Clinics
• /
• v.29 no.1
• /
• pp.78-81
• /
• 2012

A 5-year-old male Pointer dog weighing 24 kg was referred because of a chronic cough. The dog was routinely vaccinated and treated monthly with medications to prevent heartworm and endoparasites. Blood analyses revealed no abnormalities. Chest radiographs showed interstitial and bronchial patterns in the caudal lung fields. Bronchoscopic imaging identified a collapse of the left bronchus with a mucopurulent discharge, indicating the onset of bronchomalacia. Computed tomography also showed bronchial collapse and a tapering angle in the left caudal bronchus. This case study describes the diagnosis of bronchomalacia in a Pointer dog with a chronic cough, and suggests that bronchoscopic examination is a valuable tool for identifying of the onset of bronchomalacia in dogs presenting with an uncontrolled cough.

• Tuberculosis and Respiratory Diseases
• /
• v.40 no.6
• /
• pp.714-718
• /
• 1993

Tracheobronchopathia osteoplastica(TPO) is a rare disorder characterized by submucosal cartilaginous or bony projections into the tracheobronchial lumen with sparing of the posterior membranous portion of tracheobronchial tree. The etiology of TPO is still unknown. A 44-year-old male was admitted to Seoul Paik Hospital Inje University due to left chest pain for 10 days. On the past history he had sufferred from symptoms of bronchitis for several months. He showed radiologically massive pleural effusion in left lung field. Pleural biopsy revealed chronic pleuritis with hemorrhage. Bronchoscopic findings showed multiple intraluminal portruding nodule from just below the vocal cord to carina and both main bronchi. Pathology of bronchoscopic biopsy showed abnormal proliferation of atypical bony and carilagious nodules in the tracheal submucosa. We experianced a case of tracheobronchopathia osteoplastica involving the trachea and main bronchus in 44-year old male, associated with massive pleural effusion. This report is a case of TPO with review of literature.

• Proceedings of the Korea Contents Association Conference
• /
• 2011.05a
• /
• pp.197-198
• /
• 2011

임상적으로 흔한 간질환인 지방간은 대부분의 경우에 초음파검사에 의해 진단이 된다. 초음파검사에 의한 지방간과 대장암의 전구병변이 될 수 있는 대장용종과의 관련성을 검진환자대상으로 일반요인과 대사증후군 요인 등 특정요인과 비교분석 하였다. 대장용종은 나이 50세 이상, 남자일수록, 공복시 glucose와 Triglyceride 수치가 높을 때, 지방간이 있을 때 발생빈도가 높았다. 상관관계분석에서는 지방간이 용종과의 관계도가 가장 높았고 위계적 회귀분석에서도 용종발생에 가장 영향력 있는 요인은 지방간이었다. 지방간인 경우 대장내시경검사를 고려해야 할 것이다.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.12 no.2
• /
• pp.199-206
• /
• 2009

Purpose: To analyze the clinical spectrum of posttransplantation lymphoproliferative disorder (PTLD) after liver transplantation in children. Methods: From January 1988 to June 2009, we retrospectively reviewed the medical records of 8 PTLD cases among 148 pediatric patients underwent liver transplantation. The age at transplantation, time of presentation after transplantation, clinical manifestations, histologic diagnosis, results of EBV (Epstein-Barr virus) assessments, managements and outcomes of PTLD were investigated. Results: The prevalence of PTLD in liver transplant pediatric recipients was 5.4% (8 of 148). The mean age of patients was 25.4${\pm}$21.3 months (range 10 to 67 months). Seven of 8 patients (87.5%) underwent liver transplantation before 1 year of age. The common clinical presentations were persistent fever (8 of 8, 100%) and bloody diarrhea (6 of 8, 75%). PTLD was diagnosed with gastrointestinal endoscopic biopsies in five patients and surgical biopsies in three. Histologic findings showed early lesion in three patients, polymorphic in two, and monomorphic in three. Burkitt lymphoma and lymphoblastic lymphoma were found in two of 3 monomorphic patients. Seven of 8 patients were found with EBV-positive. Eight patients were treated with dose reduction of immunosuppressants and infusion of ganciclovir. Rituximab was added to four patients. PTLD were successfully managed in all patients except one who died of sepsis during chemotherapy. Conclusion: Major risk factor of PTLD was to undergo liver transplantation before 1 year of age. Continuous monitoring for EBV viral load and gastrointestinal endoscopic biopsy may be useful to early detection of PTLD.

• Journal of Yeungnam Medical Science
• /
• v.17 no.1
• /
• pp.39-48
• /
• 2000

Background: There arc two theories in the development of colon cancer. One is the adenoma-carcinoma sequence theory and the other is the de novo cancer theory. Western countries believe in the adenoma-carcinoma sequence theory, however there are many recent reports from, Japan about cancers developing from small adenomas. Methods: The present study analyzed 408 polyps from 508 cases that were taken by colonoscopic polypectomy at the Department of internal Medicine, Yeungnam University Hospital. Results: The percentage of patients who had a polyp was 41.3% (210 cases out of 526 cases), and the peak incidence was noted in patients in their 50s and 60s, There was no difference between the sexes, but we noted significant increase in the incidence of polyps in patients over the age of thirty. We found 395 polyps below 1cm and 13 polyps above 1cm. Among 408 polyps, 5 cases were cancerous polyps and 3 cases showed polyp size of less than 1cm each. The first case was a polyp of 0.4cm in size with elevated mucosa at the ascending colon. The second was 0.5cm in size with round elevation and hyperemic mucosa in the rectum. The third was 0.6cm in size with tubular elevation at the hepatic flexure. Conclusions: Colon polyp is a common disease in Koreans, Even small polyps can have cancer tissue, which should be removed if discovered during colonoscopy. We believe that not all colon cancer originates in the manner described by the adenoma-carcinoma sequence theory. However further studies with a larger sample population arc needed to determine the exact role of colon polyps in the development of colon cancer.

• Korean Journal of Microbiology
• /
• v.41 no.3
• /
• pp.177-182
• /
• 2005

H. pylori strains were isolated from antral biopsies taken during upper endoscopy in 114 dyspeptic patients with no previous therapy against H. pylori. Rapid urease test, PCR amplification of SSA and cagA gene for H. pylori detection, and Western blot for CagA expression detection were performed. H. pylori infected patients were treated with omeprazole, clarithromycin (a macrolide), and amoxicillin. At 6 weeks after the discontinuation of therapy, the bacterial eradication rate was determined by endoscopy. The resistance rate to clarithromycin and amoxicillin was $20.2\%$ and $0.0\%$, respectively. The clarithromycin resistance was mainly caused by the A2142G mutation in the 23S rRNA gene of H. pylori. MICs of clarithromycin for the A2142G mutant isolates were significantly higher than MICs for the A2143G mutant isolates. H. pylori eradication was obtained in all patients with clarithromycin-susceptible isolates but not in patients with clarithromycin-resistant isolates (P = 0.0001). These results did not appear to be biased by any differences in CagA expression. The resistance of H. pylori to clarithromycin included in the therapeutic regimens is the most important reason for treatment failure. H. pylori antimicrobial susceptibility testing of the gastric biopsy culture should be performed before choosing the first triple therapy in infected patients and the increase in prevalence of clarithromycin resistance in Korea was problematic.