• Journal of dental hygiene science
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• v.7 no.1
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• pp.9-12
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• 2007

Streptococcus mutans is the major causative factor in dental caries and has been known to induce dental caries by the process of initial attachment proliferation and acid production. The pH of Streptococcus mutans(S. mutans) media and glucosyltransferase(GTase) activity were determined to evaluate the anticariogenic activity of Dioscorea batatas and Prunella vulgaris hexane fraction. In the experiment of hexane fraction of Dioscorea batatas, the relative growth ratio(RGR) against Streptococcus mutans (S. mutans) was determined as 93% in concentration of 0.125 mg/ml, 100% in 0.25 mg/ml. The hexane fraction of Prunella vulgaris revealed relative growth ratio(RGR) against Streptococcus mutans (S. mutans) as 86% in concentration of 0.25 mg/ml, 100% in 0.5 mg/ml. The relative growth ratio(RGR) against of hexane fraction were determined as 92% in concentration of 0.25 mg/ml, 100% in 0.5 mg/ml. The acidities were pH 7.2 on Dioscorea batatas and 7.0 on Prunella vulgaris in 2.0 mg/ml in contrast to pH 5.6 on Dioscorea batatas and 5.2 on Prunella vulgaris in control. The inhibitory effect to activity revealed 35% on Dioscorea batatas and 25% on Prunella vulgaris in 2.0 mg/ml. The inhibitory effect of Dioscorea batatas was more potent than Prunella vulgaris.

• Journal of The Korean Society of Clinical Toxicology
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• v.4 no.1
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• pp.78-81
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• 2006

Mad-honey poisoning is mainly brought about by the honey imported from Napal, Turkey, Brazil and other parts of Europe. This mad honey is extracted from Ericaceae plants of Rhododendron species and contains grayanotoxins that causes poisoning. These toxic compounds exert a specific stimulatory action on membrane permeability to Na+ions in various excitable tissues and cause depolarization of cell membranes. The toxic effects of grayanotoxins contained honey are mainly cardiovascular disturbances with bradycardia, cardiac arrhythmia, hypotension. There are Other symptoms like nausea, vomiting, salivation, dizziness, weakness and loss of consciousness. The precise amount for a toxic dose is not known. In general the severity of the honey poisoning depends on the amount ingested. Two cases of mad-honey poisoning are described here. Both patients showed bradycardia and arterial hypotension after ingestion of honey which was brought from Nepal. They were recovered fully within 24 hours after administration of fluids and atropine sulphate.

• Journal of Nutrition and Health
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• v.40 no.sup
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• pp.39-49
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• 2007

본 논문은 미국 의학연구소(US Institute of Medicine, IOM)와 미국 농무성의 식이지침 자문위원회(USDA Advisory Committee on Dietary Guidelines, DG)에서 발표한 권위 있는 종설 들과 미국 영양사협회 학술지를 포함하여 여러 학술지에 발표된 의미 있는 종설 들의 내용을 종합한 것으로 일부의 내용은 그들의 의견을 그대로 반영하였다. 당은 단당류와 이당류를 말하며 당에는 포도당, 과당, 갈락토오즈, 맥아당, 서당과 유당이 포함된다. 당의 식품급원으로는 고과당 옥수수시럽, 사탕수수, 꿀, 사탕수수, 맥아시럽 등이 있다. 당은 미국 식약청에서 일반적으로 안전하다고 인식(generally recognized as safe, GRAS)되고 있다. 당은 에너지를 공급하며, 정신적인 만족감을 부여하는 기능을 가지고 있다. 대부분의 과일과 유제품은 당을 많이 함유하고 있으며, 건강한 식사를 구성하는 식품으로 섭취되고 있다. 당은 또한 조리와 가공과정에서 식품의 맛과 기능적인 면을 향상시키기 위해 첨가되기도 한다. 당은 영양밀도가 높은 식품/음료의 기호성(palatability)를 향상시키므로, 감미료들은 건강한 식사가 되도록 도와줄 수 있다. 그러나 첨가당의 섭취가 증가되면 식사의 영양밀도가 감소하는 가능성에 대한 우려가 있다. 여러 연구에 의하면 첨가당의 섭취가 총 열량 섭취의 25% 이상이 되면 식품의 영양밀도 감소가 나타날 수 있다고 보고하고 있다. 한국에서 추정된 당의 섭취량은 이것보다는 매우 낮은 수준이다. 선진국들에서 당의 섭취가 건강에 부정적인 영향을 줄 수 있다는 가능성에 대해서는 많은 논란이 되고 있다. 그러나 적절한 양을 섭취하는 범위에서 당의 섭취 자체만으로는 비만, 당뇨병, 대사증후군과 고콜레스테롤혈증의 위험이 증가되지 않는다는 과학적인 연구보고들이 있다. 그러므로 IOM은 "여러 자료에 근거하여, 충치, 행동적인 문제, 암, 비만의 위험성과 고지혈증의 위험성에 있어서 총 당과 첨가당에 대한 상한섭취량(tolerable upper limit)을 설정하는 것에 대한 증거가 불충분하다"고 결론을 내리고 있다.

• Korean Journal of Plant Resources
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• v.26 no.4
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• pp.450-456
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• 2013

We investigated the optimal cultivation system and dry processing method of rhizomes from Curcuma longa L. in Suncheon, the southern area of Korea. The experimental results are summarized as followings. Curcma longa rhizomes were transplanted on Apr. 30th, May 10th, and May 20th. The plant height, stem diameter, number of leaves and yield were highest in transplanted on May 10th. The fresh rhizome weight of Curcma longa was the heaviest in November 20 and the optimal dry temperature was $40^{\circ}C$. In sensory evaluations, there were significant differences among the Curcuma longa pills in terms of flavor, color, color and texture and overall acceptability, and honey added groups received significantly higher scores than the other groups.

• Proceedings of the Korean Society of Computer Information Conference
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• 2014.07a
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• pp.499-502
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• 2014

본 논문에서는 'M-virus'게임의 설명과 작업자들의 제작의도를 보여준다. 'M-virus'는 '꿀사주세요'팀의 졸업 작품 게임으로 딸의 감염을 치료하기 위해 숙주를 찾는 아버지의 스토리를 기반으로한 3인칭 액션게임이다. '캐릭터 변이'를 특징으로 플레이어의 성향에 따라 캐릭터를 자유자재로 바꿀 수 있으며 캐릭터마다의 고유 스킬로 다양한 플레이를 경험할 수 있다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.39 no.1
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• pp.75-81
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• 2013

Chrysin (5,7-dihydroxyflavone) is a natural flavonoid found in various plants and foods such as propolis and honey. It has been reported that chrysin has various biological effects including antioxidant, anti-aging, anti-inflammatory and anti-cancer. In this study, we investigated the effect of chrysin on the transcriptional activity of VDR in human epidermal keratinocytes by performing dual-luciferase assay. Chrysin significantly induced the transcriptional activity of VDR in a concentration-dependent manner. The VDR mRNA expression was investigated by quantitative real time PCR and chrysin increased the VDR mRNA expression in normal human epidermal keratinocytes. We also found that chrysin increased the expression of keratinocyte differentiation markers such as keratin 10, involucrin and filaggrin. Therefore, the results suggest that chrysin can stimulate the differentiation of human keratinocytes by increasing transcriptional activity of VDR.

• Research in Plant Disease
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• v.12 no.2
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• pp.125-128
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• 2006

Downy mildew caused by Pseudoperonospora cubensis (Berkeley & Curtis) occurred on the cotyledon of gourd (Lagenaria leucantha cv. Sambokkkul) and scion of watermelon (cv. FR couple) in commercial nursery around Jinju city, Gyeongnam province in Korea in 2005 and 2006. The disease symptoms usually started with water-soaking lesions on cotyledon and then the infected leaves became withered and eventually died. The sporangia of the pathogen were one-celled, ovoid to ellipsoid in shape, pale grayish in color, and $20{\sim}32{\times}14{\sim}18{\mu}m$ in size. Sporangiophores were errect, branched, and $140{\sim}380{\times}4{\sim}8{\mu}m$ in size. Pathogenicity of the causal organism was proved according to artificial inoculations. Although the virulence of the causal fungus on the host plants was not strong, it produced typical symptoms. The causal organism was identified as Pseudoperonospora cubensis (Berkeley & Curtis) based on the mycological characteristics of the fungus and pathogenicity. This is the first report on downy mildew of watermelon caused by P. cubensis in Korea.

• Korean Journal of Food Science and Technology
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• v.50 no.3
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• pp.280-285
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• 2018

Lipid oxidation and antioxidant stabilities of nut-sesame yeotgangjeong (Korean traditional candy bar) with different binders were evaluated during storage in the dark. S1, S2, and S3 binders consisted of starch syrup, sugar, and water (58:34:7.6, w/w/w); starch syrup, jocheong, honey, trehalose, and water (43.5:11.6:2.9:34:7.6, w/w/w/w/w); and starch syrup, jocheong, honey, sugar, trehalose, and water (43.5:11.6:2.9:17:17:7.6, w/w/w/w/w/w); respectively. Lipid oxidation was determined by peroxide and p-anisidine values, and tocopherol, lignan, and polyphenol contents were determined spectrophotometrically. Peroxide values were significantly higher (p<0.05) in yeotgangjeong samples with S2 or S3 binder than in those with S1; however, the converse was true for tocopherol degradation. Lignan was the most stable antioxidant in yeotgangjeong. The results suggest that tocopherols have a priority over lignans to control the lipid oxidation of yeotgangjeong during storage; reduced lipid oxidative stability after substituting sugar with trehalose might be because it increases oxygen diffusivity and inhibits the antioxidant action of tocopherols on lipids.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2022.09a
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• pp.65-65
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• 2022

지속가능한 DMZ 일원의 생태복원 추진을 위해 DMZ 생태교란지에서 복원공법 모니터링을 실시하였다. 본 실험은 강원도 인제군, 철원군 및 경기도 연천군의 DMZ 내(450m²)에서 진행되었으며, 흰민들레, 구절초, 매발톱, 질경이, 꿀풀이 공시식물로 사용되었다. 각 대상지의 식생유형별 시공방법에 따른 침입종 억제효과를 알아보기 위해 2022년 4월부터 9월까지 일반식생기반재와 특수식생기반재로 처리된 실험구의 전체 피도, 도입종 피도, 침입종 피도, 초장, 출현종 등을 측정하였다. 전체 피도는 세 곳 모두 일반 기반재보다 특수기반재에서 더 높게 나타났으나 대상지에 따라 침입종 피도가 미치는 영향은 달랐다. 도입종의 피도는 인제, 철원, 연천에서 동일하게 흰민들레가 가장 높은 수치를 보였고, 특수기반재에서 보다 높은 피도를 보였다. 폭염 및 폭우로 6월 이후 흰민들레가 감소하면서 구절초, 매발톱의 피도가 점차 증가하였으며 기반재 간의 큰 차이는 없었으나 일부 지역에서는 구절초 피도가 특수기반재보다 일반기반재에서 더 높게 나타났다. 또한, 모든 지역에서 질경이와 꿀풀의 생장은 미미하였다. 같은 처리를 했음에도 대상지별로 소재식물의 출현 여부, 생장률, 침입종의 피도 등이 다른 것으로 보아 복원지의 환경 여건에 따라 적용해야 하는 종, 시공방법, 주변 완충지역의 범위 등에 차이를 두어야 할 것으로 보인다.

• Horticultural Science & Technology
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• v.33 no.3
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• pp.409-419
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• 2015

This study was conducted to establish an efficient screening method for watermelon plants resistant to Fusarium wilt (FW), which is caused by Fusarium oxysporum f. sp. niveum (Fon). An HA isolate was prepared from a wilted watermelon plant in Haman-gun and identified as F. oxysporum f. sp. niveum based on morphological characteristics, molecular analyses of ITS (internal transcribed spacer) and TEF (translation elongation factor $1{\alpha}$) sequences, and host specificity on cucurbits including watermelon, melon, oriental melon, and cucumber. The assay for disease response of watermelon differentials indicated that the HA isolate was race 0. Among seven liquid media tested, the highest amount of Fon spores was produced from V8-juice broth, which was selected as a medium for mass production of Fon. The disease assay for 21 watermelon and 11 watermelon-rootstock cultivars demonstrated that 20 watermelon cultivars except for 'Soknoranggul' were susceptible; 'Soknoranggul' was moderately resistant. All the tested rootstock cultivars were highly resistant to the HA isolate. The evaluation of disease development depending on various conditions suggested that an efficient screening method for FW resistance in watermelon plants is to dip the roots of 10-day-old seedlings in spore suspension of $1.0{\times}10^5-1.0{\times}10^6conidia{\cdot}mL^{-1}$ for 30 min., to transplant the seedlings to plastic pots with a fertilized soil, and then to cultivate the plants at $25^{\circ}C$ for 3 weeks.