• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.15 no.2
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• pp.261-270
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• 2002

the result of literature study on poliosis is like these. 1. The poliosis, was to known as one of aging, was to conclude as a symptom of pathologic state. 2. The aetiology of poliosis is on deficiency of kidney, three yangmeak, psychologic fact, heat and other disease. 3. The primary treatment of poliosis is on reinforcing of liver and kidney, Ki and blood.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.1
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• pp.83-91
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• 2019

Objectives : The purpose of this study is to report the effect of Korean medical treatment on prurigo pigmentosa which is so rare in asia except Japan. Methods : We experienced two cases of prurigo pigmentosa treated with herbal medicine, herbal-acupuncture, acupuncture. After treatment, we measured the change of symptoms including itching, erythematous papules. Results & Conclusions : Symptoms of prurigo pigmentosa were improved remarkably. According to the results, it is considered that the Korean medical treatment can be effective for the treatment of prurigo pigmentosa.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• v.61 no.11
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• pp.615-618
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• 2018

The central giant cell granuloma is a benign tumor seen generally in the mandible, but rarely in other cranial bones. Herein, we present a 51-year-old man with central giant cell granuloma in the right zygomatic bone. Physical and radiologic examinations of the central giant cell granuloma in the zygomatic bone showed that specific and preoperative diagnosis is usually difficult. Therefore, clinicians should consider the possibility that central giant cell granuloma may occur in the zygomatic bone mimicking other more frequently observed lesions.

• Korean Journal of Head & Neck Oncology
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• v.35 no.1
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• pp.41-44
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• 2019

Intraductal papilloma is an extremely rare benign tumor especially when it arises from major salivary gland. Recently, we experienced a case of an intraductal papilloma arising from the parotid gland in a 51-year-old woman. The radiologic finding showed lobulated enhancing and cystic solid mass in the left parotid superficial lobe. Superficial parotidectomy was performed. Pathological findings showed papillary proliferations with fibrovascular cores lined with bland cuboidal or columnar epithelial cells, and immunohistochemical stain results were consistent with intraductal papilloma. We report a case of intraductal papilloma in parotid gland with a review of literature.

• Korean Journal of Head & Neck Oncology
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• v.37 no.2
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• pp.97-100
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• 2021

Pilomatricoma(or calcifying epithelioma) is a not common benign solitary tumor originated from outer root sheath cell of hair follicle or hair follicle of sebaceous glands. The tumor usually presents as an asymptomatic, hard, superficial located, and skin colored to reddish blue cutaneous mass. Most of the tumors are less than 10mm in diameter and adherent to the skin. Recently, 48-year-old man presented with cheek mass. The tumor was 2.6cm sized and located at the subcutaneous layer of cheek on CT scan. The tumor was clearly removed via transoral approach with buccal incision leaving no wound on face. The mass was confirmed as pilomatricoma on pathologic examination. Herein, we report our experience with literature review.

• Korean Journal of Head & Neck Oncology
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• v.37 no.2
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• pp.61-65
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• 2021

Epithelial-myoepithelial carcinoma is rare, low-grade malignant neoplasm that compromises approximately 1% of all salivary gland neoplasms. We reported a 68-year-old woman with epithelial-myoepithelial carcinoma in the parotid gland. We analyzed demographic and clinicopathological characteristics of salivary gland epithelial-myoepithelial carcinoma which has been reported in 33 cases in Korea from 1992 to 2017, and compared this result to overseas retrospective cohort studies. There was no significance in terms of mean age at diagnosis, the predominance of females, low frequency in regional lymph nodes, and distant metastasis between the two groups. However, T classification and AJCC stage at diagnosis in domestic cases are more advanced than those of overseas cases. Although the recurrence rate in domestic cases has been reported lower than that of overseas, further study may be needed considering that the follow-up period after treatment is short in domestic cases.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.36 no.3
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• pp.1-11
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• 2023

Objectives : The objective of this study is to identify the characteristics of outpatients and the frequently diagnosed diseases in dermatology of Korean medicine through periodic research and comparison with previous studies. Methods : We analyzed medical records of new outpatients who visited department of dermatology at Kyung Hee university Korean medicine hospital between January 1, 2018 and December 31, 2022. We analyzed the patient demographic characteristics and the frequency of diagnosed diseases. Then we compared these results with previous studies in 2000, 2007 and 2016. Results : 1. Average number of patients and proportion of male patients have increased from 1996 to 2022. 2. From 1996 to 2022, there was a decrease in the proportion of patients aged 0-39 and an increase in the proportion of patients aged over 40. 3. The distribution proportions of eczema, atopic dermatitis, and rosacea during 2018-2022 have increased compared to those during 2011-2015. 4. The distribution of diseases according to age appears to vary based on the epidemiological characteristics of the diseases. 5. The distribution of diseases according to gender also appears to vary based on the epidemiological characteristics of the diseases, as well as cosmetic issues related to the affected areas. Conclusions : Considering the sustained trend of a high proportion of non-infectious inflammatory diseases since 1996, it is important to enhance treatment capacity through continuous research.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.36 no.4
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• pp.30-50
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• 2023

Objectives : To investigate the active compounds and therapeutic mechanisms of Atractylodes Lancea(Thunb.) D.C. and Magnolia Officinalis Rehder et Wilson in the treatment of dermatitis accompanied by pruritus, as well as their potential to complement or replace standard drugs. Methods : We conducted the network pharmacological analysis. We selected effective ingredients among the active compounds of research target herbs. Then we explore pathway/terms of the common target proteins among research target herbs, fexofenadine and disease. Results : We selected 9 active compounds are selected from Atractylodes lancea and identified 231 target proteins. Among them, 74 proteins are associated with inflammatory skin diseases that cause pruritus. These proteins are involved in various pathways including, 'Nitric-oxide synthase regulator activity', 'Hydroperoxy icosatetraenoate dehydratase activity, Aromatase activity', 'RNA-directed DNA polymerase activity', 'Arachidonic acid metabolism', 'Peptide hormone processing', 'Chemokine binding' and 'Sterol biosynthetic process'. Additionally, coregenes are involved in 'IL-17 signaling pathway'. Similarly, we selected 2 active compounds from Magnolia officinalis and identified 133 target proteins. Among them, 33 proteins are related to inflammatory skin diseases that cause pruritus. These proteins are primarily involved in 'Vascular associated smooth muscle cell proliferation' and 'Arachidonic acid metabolism'. There is no significant difference between the pathways in which coregenes are involved. Conclusions : It is expected that Atractylodes Lancea will be able to show direct or indirect anti-pruritus and anti-inflammatory effects on skin inflammation accompanied pruritus through suppressing inflammation and protecting skin barrier. Meanwhile, it is expected that Magnolia Officinalis will only be able to show indirect anti-inflammation effects. Therefore, Atractylodes Lancea and fexofenadine are believed to complement each other, whereas Magnolia Officialinalis is expected to provide supplementary support on skin disease.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.4
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• pp.1-30
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• 2022

Objectives : The purpose of this study was to explore the experience of patients with facial palsy symptoms treated with Korean medicine treatment(KMT) after western treatment. Methods : We conducted an individual in-depth interview with 10 participants who had experience in both western and KMT for facial palsy symptoms. This qualitative study adopted the grounded theory of Strauss and Corbin, and collected data was analyzed by using coding(open-axial-selective) that was performed to create paradigm model, which can explain this study's main theme. Results : The central phenomenon of this study was 'choosing Korean medicine treatment after western treatment preceded', and the core category was derived as 'selecting process of KMT after western medical treatment and improvement plan of Korean medicine treatment'. Conclusions : For patients with facial palsy, KMT was perceived as an essential treatment rather than an alternative, and recognized as the main treatment. Patients didn't settle for western treatment which was in progress, actively selected KMT and suggested the specific plan for improvement of KMT. Through this, we should be considered the direction of the KMT for facial palsy symptom which is the common disease of KMT.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.1
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• pp.58-62
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• 2022

Objectives : The aim of this study is to report the effect of long-term acupuncture on a amblyopia derived from astigmatism. Methods : A 39-month-old-female child presented with decreased visual acuity with simple astigmatism and amblyopia in the left eye. She took long-term acupuncture treatment once or twice a week for almost four years. And the autorefractor follow-up were conducted per every 6 months. Results : At the initial visit, naked eye visual acuity was 0.1/0.7(OD/OS), Sph. +0.00D, Cyl. -2.25D, AXIS 148° in the right eye, and Sph. +0.00D, Cyl. -0.25D, AXIS 49° in the left eye. After acupuncture treatment for about 4 years without correctional glasses, the visual acuity of the right eye was 1.0, the right eye had Sph. +0.00D, Cyl -0.50D, AXIS 146°, and the left eye had Sph. -0.25D, Cyl -0.50D, AXIS 154°. The visual acuity was maintained until 1 year follow up as 0.9/1.0(OD/OS). Conclusions : This study shows the possibility of using acupuncture treatment for amblyopia derived from astigmatism.