• Title/Summary/Keyword: 김선양

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Surgical Treatment of Adenoid Cystic Carcinoma by Left Tracheal Sleeve Pneumonectomy (좌측 수상 전폐 적출술에 의한 선양 낭포암 치험 1례)

  • 김동원
    • Journal of Chest Surgery
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    • v.27 no.5
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    • pp.413-417
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    • 1994
  • Adenoid cystic carcinoma usually grows in the trachea or near its bifurcation and causes obstruction of the air way. We recently experienced a 33 year-old male patient who had adenoid cystic carcinoma in the left main bronchus with the chief complaint of productive cough. On the bronchoscopy, the mass obstructed the left main bronchus completely and had nodularity and increased vascularity.The trachea was shifted to the left side and the lower lobe of the left lung was atelectatic on chest X-ray and computed axial tomogram.He underwent left tracheal sleeve pneumonectomy and lymph node dissection through bilateral thoracotomy. At first,we attempted left tracheal sleeve pneumonectomy through the left thoracotomy,however, it was very difficult to perform carinoplastic procedure after sleeve resection of 2.5cm of distal trachea and 1cm of proximal right main bronchus including whole left lung because of poor operative field and difficulty in the anastomosis of the right main bronchus to the distal end of the trachea without tension.Therefore after radical resection of the left lung we made right thoracotomy,through which we could anastomosed the distal trachea and right main bronchus with 4-0 PDS interrupted suture after mobilization of the right hilum without difficulty. The tumor was confirmed to be adenoid cystic carcinoma with metastasis to subcarinal lymph node histopathologically. Postoperative course was uneventful but he needed two bronchoscopic procedure to clear distal airway of the retained bronchial secretion. He was discharged at 14 days after operation with complete recovery.

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Time Cource Variation of Metatarsus Mineral Content after UV Exposure to Dorsal Skin of Broiler Chicks (브로일러 병아리의 등 피부에 자외선 조사후 중족골 무기물 함량의 경시적 변화)

  • 장윤환;강훈석;김강수;원지웅
    • Korean Journal of Poultry Science
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    • v.19 no.1
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    • pp.35-45
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    • 1992
  • This study was carried out to investigate the effect of different dose of 312nm UV irradiation on ash and phosphorus contents in metatarsus of broiler chicks, whose dorsal skins were exposed to the UV light. Day old Hubbard line broiler chicks were fed with vitamin D deficient diet for 3 weeks and the defeathered dorsal skins were exposed to different dise (0.32, 0.65, or 0.98 J/$\textrm{cm}^2$) of 312nm UV light. The metatarsus bones were collected on 0, 1, 2, 3, 4 or 5 days after irradiation and defatted, dried, ashed and dissolved in 6N-HCI. The P concentrations were determined by spectrophotometry. When the 0.32 J/$\textrm{cm}^2$ dose was applied, the ash contents in metatarsus bones o( chicks were 42, 46 and 40% on 0, 1 and 3 days after irradiation, respectively. The maximum level, 46% was appeared at 2 days after exposure as 0.65 J/$\textrm{cm}^2$ was treated. When 0.98 J/$\textrm{cm}^2$ irradiation was applied, the high concentrations, 47 and 47% were shown on 1 and 2 days after irradiation, respectively. The 0.98 J/$\textrm{cm}^2$ among three levels of dose increased the most amount of ash in metatarsus bone. In respect to the P content in the chick bone the increased level, 19.4% was shown on 3 days after UV treatment with 0.32 J/$\textrm{cm}^2$. The maximum levels, 18.1 and 20.0% were present on 3 and 2 days after exposure to the 0.65 and 0.98 J/$\textrm{cm}^2$ of UV dose, respectively. It was shown that the higher dose of UV irradiation increased the more P concentration in matatarsus of chicks and the production rate was faster than those from 0.32 and 0.65 J/$\textrm{cm}^2$ treatments.

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Time Course Variation of Liver 25-Bydroxyvitamin $D_3$ Content in Broiler Chicks Exposed to UVB Light with Different Dobe (상이한 선양의 자외선을 조사한 브로일러 병아리에 있어서 간장 25-Hydroxyvitamin $D_3$회량의 계치적 변화)

  • 장윤환;강훈석;여영수;김강수;조인호;배은경
    • Korean Journal of Poultry Science
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    • v.19 no.4
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    • pp.217-225
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    • 1992
  • This research was carried out to determine the 25-Hydroxyvitamin $D_3$[25(OH)$D_3$] content in liver of broiler Hubbard chicks fed vitamin VD-deficient diet for 31 days in a subdued light room and exposed to UVB light (maximum intensity at 297nm) with dose of 0.204 or 0.408 mJ/$\textrm{cm}^2$(30 or 60 min irradiation) . The lipid in liver collected at 0~138 hr after irradiation was extracted by chloroform-methanol(2:1, v /v) and 25(OH)$D_3$ fraction was separated by Sep-Pak silica cartridge. The 25(OH)$D_3$ concentration was measured by normal phase HPLC. The negative control chicks Presented 25(OH)D$_3$17.5 ng/g liver. When 0.204mJ/$\textrm{cm}^2$ was treated to whole body of chicks, the 25(OH)$D_3$ level was increased to 37.8 ng/g at 12 hr after irradiation, the peak concentration, 40.5 ng /g was appeared at the time of 86 hr, and decreasing trend was shown thereafter until 138 hr, the final time in this study. When 0.408 mJ/$\textrm{cm}^2$ was applied, the 25(OH)$D_3$ content was 36.7 ng /g liver at 12 hr, 61.4 ng/g(maximum value ) was appeared at 42 hr, and 39.5 ng /g at 138 hr. The increased absolute amounts in liver 25(OH)$D_3$ were 23 and 43.9 ng/g as chicks were exposed to UVB light with dose of 0.204 and 0.408mJ/$\textrm{cm}^2$, respectively. Consequently, it was found that when double dose of UVB light was irradiated to the chicks, their liver samples produced nearly double 25(OH)$D_3$ at 42 hr after exposure, and the peak value was presented earlier by 24 hr than that in the low dose treatment.

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Fine Needle Aspiration Cytology of Solid Type Adenoid Cystic Carcinoma of Buccal Mucosa - A Case Report - (뺨 점막에 발생한 충실성 선양낭성암종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Kim, Jean-A;Kim, Young-Sill;Lee, An-Hi;Shim, Sang-In;Kim, Byung-Kee;Kim, Kyoung-Mee
    • The Korean Journal of Cytopathology
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    • v.11 no.2
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    • pp.89-92
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    • 2000
  • Adenoid cystic carcinoma constitutes 4 percent of ail benign and malignant epithelial salivary gland tumors and is a highly malignant tumor of the salivary glands. The cytologic presentation in aspirates is usually characteristic with spherical clusters(balls) of small tumor cells filled with hyaline material. But in case of the poorly differentiated variety(solid type), it is difficult to differentiate from other tumors because sheets of small, fairly monotonous malignant cells, with somewhat larger and more conspicuous nuclei are only seen. The cytologic findings of fine needle aspiration of solid type adenoid cystic carcinoma of buccal mucosa in a 51-year-old man are presented. On cytologic findings, solid sheets of monotonous tumor cells with focal necrosis was noted on a hemorrhagic background and the characteristic cytologic features of adenoid cystic carcinoma was absent.

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Clinicopathologic Predictors and Impact of Distant Metastasis from Adenoid Cystic Carcinoma of the Head and Neck (두경부 전양낭성암종에서 원격전이와 관련된 임상적, 병리학적 예측 인자)

  • Kim Jeong-Whun;Kim Kwang-Hyun;Kwon Taek-Kyun;Lee Sang-Joon;Sung Myung-Whun
    • Korean Journal of Head & Neck Oncology
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    • v.18 no.2
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    • pp.157-162
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    • 2002
  • Background and Objectives: Adenoid cystic carcinoma (ACC) is a unique tumor characterized by frequent and delayed distant metastasis (DM) with uncommon regional lymph node metastasis. We evaluated the factors affecting DM of ACC and survival after appearance of DM. Materials and Methods: Medical records, radiographs and pathologic slides were reviewed for 94 patients from 1979 through 2001. Results: DM of ACC occurred in 46 patients, and developed more frequently in patients with tumors of the solid histologic subtype than in patients with tubular or cribriform subtypes. DM occurred less frequently in the sinonasal tract, and development of DM was not affected by tumor stage. Disease-specific 5- and 10-year survival rates were 88% and 72% for patients without DM, respectively and 76% and 48% for those with DM(p=0.02). Regarding the site of DM and its impact on outcomes, 30 patients had lung metastasis alone, 5 patients bone metastasis alone and 6 patients developed both lung and bone metastasis. Median survivals after appearance of DM among patients with isolated lung metastases and those with bone metastases with or without lung involvement were 54 and 21 months, respectively (p=0.04). Conclusions: Development of DM in ACC is predicted by solid histologic subtype, and major salivary gland or oral/pharyngeal rather than sinonasal primary site. Those patients with bone involvement with our without lung metastases had worse outcomes than those with pulmonary metastasis only.

Combined Adenomatoid Odontogenic Tumor and Calcifying Epithelial Odontogenic Tumor in the Mandible: Case Report (하악 소구치 부위에 발생한 석회화상피성치성종양이 혼재된 선양치성종양: 증례보고)

  • Noh, Lyang-Seok;Jo, Hyung-Woo;Choi, So-Young;Kim, Chin-Soo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.33 no.2
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    • pp.176-179
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    • 2011
  • Adenomatoid odontogenic tumors represent 3 to 7 percent of all odontogenic tumors. These tumors are more common in the maxilla than the mandible and usually include the anterior region. Clinically, the most common symptom is painless swelling and the tumor is associated with an unerupted tooth, typically a maxillary or mandibular cuspid. The adenomatoid odontogenic tumor appears radiographically as a unilocular radiolucency around the crown of an impacted tooth, resembling a dentigerous cyst. More often, it contains fine calcifications. Histopathologically, there is a thick wall cystic structure with a prominent intraluminal proliferation of the odontogenic epithelium. The most striking pattern is varying-sized solid nodules of spindle-shaped or cuboidal epithelial cells forming nests or rosette-like structures with minimal stromal connective tissues. Conspicuous within the cellular areas are structures of tubular or duct-like appearance. The duct-like spaces are lined with a single row of cuboidal or low columnar epithelial cells, of which the ovoid nuclei are polarized away from the luminal surface. Small foci of calcification may also be scattered throughout the tumor. These have been interpreted as abortive enamel formations. In some adenomatoid odontogenic tumors, the material has been interpreted as dentoid or cementum.

When Fashion Brand Reveals a Secrete -A Fashion Brand's CSR Information Transparency and Consumer Evaluation- (패션 브랜드가 비밀을 밝힐 때 -패션 브랜드의 CSR 정보 투명성과 소비자 평가-)

  • Kim, Songmee;Park, Sunyang;Kim, Hayoun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.44 no.3
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    • pp.385-399
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    • 2020
  • Corporate social responsibility is a consistently discussed theme in many industries. Most corporations engage in CSR activities and now inform consumers in detail on what they have been doing for society. It has become a critical tool of consumer communication; however, little is known regarding the role of information transparency in the context of the fashion industry. This study discusses information transparency of fashion corporations which means revealing information regarding cost and garment making processes. The research proved that the higher consumers perceive a fashion brand's CSR performance (CSP), the more they think the provided CSR information is substantial; consequently, there is a favorable evaluation of the brand. The result provides insight regarding the relationship between CSP perception, perceived information substantiality, and brand evaluation. There was a significant partial mediation effect of perceived information substantiality. Moreover, the moderated mediation effect of information transparency appeared significant on the impact of CSP perception for brand evaluation via CSR information substantiality. The process model 7 was used as an analytical tool. The results of this study implies the importance of information transparency in the fashion industry context in the digital era.

Characteristics and Applications of Soild State Nuclear Track Detectors -The Detection and Dosimetry of N-Ions by CR-39- (고체비적검출기(固體飛跡檢出器)의 특성(特性)과 그 응용(應用) -CR-39에 의한 질소(窒素)이온 검출(檢出)과 선양측정(線量測定)-)

  • Kang, Yung-Ho;Kim, Do-Sung
    • Journal of Radiation Protection and Research
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    • v.9 no.2
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    • pp.55-60
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    • 1984
  • The optimum etching condition of allyl diglycol carbonate (CR-39) for detecting the 60 MeV N-ions was determined as $70^{\circ}C$, 20% NaOH for 130min, by considering the variations of track density and diameter. Under these conditions, the maximum detectable track density was $1.7{\times}10^7tr/cm^2$. Track densities were linearly increased with increase of the total charge of the incident 60 MeV N-ions. By considering the scattring of N-ions as the Rutherford elastic scattering of point source, the measured relative probability was well consistent with the calculated value. The detection efficiency of CR-39 was in the range of 54-41% for 60 MeV N-ions of 12 nC-100 nC.

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Immunohistochemical Study of Psoriasis-related Gene Expression in Imiquimod-induced Psoriasis-like Mouse Model (이미퀴모드로 유발된 건선양 쥐 모델에서 건선 연관 유전자 발현에 대한 면역조직화학적 연구)

  • Kim, Ji-Young;Choi, Mi-Ra;Choi, Chong-Won;Park, Kyung-Duck;Lee, Young;Kim, Chang-Deok;Seo, Young-Joon;Lee, Jeung-Hoon
    • Korean journal of dermatology
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    • v.56 no.10
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    • pp.609-613
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    • 2018
  • Background: Psoriasis is a chronic inflammatory skin disease with an incidence of 0.5~3% of the worldwide population. The pathogenesis of psoriasis is related to dysregulated keratinocyte function and immune reactions. Notably, genetic factors are considered important etiological contributors. Globally, several researchers have recently performed genome-wide association studies (GWAS) to identify the genes related with psoriasis. Objective: We aimed to investigate the expression pattern of 2 candidate genes that were identified by GWAS. These include interleukin 28 receptor alpha (IL28RA) and CUB and Sushi multiple domains 1 (CSMD1). Methods: We applied imiquimod cream to develop a psoriasis-like mouse model and obtained skin tissue. We performed immunohistochemistry to detect the expression of IL-28A and CSMD1. Results: IL28RA expression increased at an early time point such as 1 day after the topical application of 5% imiquimod cream. However, its expression returned to baseline levels 2 weeks after the topical application of imiquimod cream. CSMD1 expression also increased after the topical application of imiquimod, with increased expression particularly observed in the upper epidermal layer. Notably, CSMD1 expression decreased 7 days after imiquimod cream application. Conclusion: These results suggest that IL28RA and CSMD1 may play key roles in the pathogenesis of psoriasis.

The Study of CSR Communication Effectiveness of Fashion Store Design (패션 매장 디자인의 CSR 커뮤니케이션 효율성에 관한 연구)

  • Park, Sunyang;Kim, Hayoun;Jeong, Yeojin;Lee, Yuri
    • Journal of the Korean Society of Clothing and Textiles
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    • v.43 no.2
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    • pp.274-287
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    • 2019
  • Most corporations engage in Corporate Social Responsibility (CSR) activities. Consumers are aware of CSR activities in different domains and use the perception and evaluation in purchase decision making. This study reveals how the relationship between consumer perception about a fashion corporation's CSR activities and product evaluation (such as perceived expertise and attractiveness) affects behavioral intention. This study discussed implications for store designs depending on whether it is actively engaging in CSR communication. Two virtual fashion store images of modern or eco design were used as stimuli. The study was conducted from July to August, 2018 based on women in their 20s and 30s. We collected 154 eco designs and 157 modern design responses. The findings of the study show that consumer perceptions of CSR activities affected perceived expertise and attractiveness. Further, perceived expertise and attracti-veness led to purchase intention and time spent in the store. The store design variation had no differences in mean values of consumer perception; however, evaluation and purchase intention indicated that a varied store design emphasized different corporation capabilities.