• Pediatric Infection and Vaccine
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• v.24 no.3
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• pp.168-177
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• 2017

Purpose: The purpose of this study was to analyze the clinical features and risk factors of invasive infections caused by Lactobacillus spp. and Saccharomyces spp., components of commercially available probiotics. Methods: We analyzed demographic and clinical data from children ${\leq}18$ years of age with an invasive infection caused by Lactobacillus spp. or Saccharomyces spp. at the Asan Medical Center Children's Hospital from January 1998 to June 2016. Probiotic consumption data were also analyzed. Results: During the study period, a total of 24 episodes of invasive infections were caused by Lactobacillus spp. (n=16) and Saccharomyces cerevisiae (n=8). Along with the increase of probiotic use (755,594 [days/1,000 patient-admission days] in 2001 to 2005, 1,444,066 in 2006 to 2010, and 6,904,736 in 2011 to 2016), the incidence of probiotic-associated invasive infection increased ($R^2=0.70$). The median age of the patients was 1.8 years (range, 2 months to 17 years), and most of them had underlying medical conditions. The 30-day mortality rate was 20.8% (5/24), and 11 (45.8%) of these patients resulted from a severe invasive infection. We determined the risk factors for invasive infection to be: previous intensive care unit stay (odds ratio [OR], 3.0; 95% confidence interval [CI], 1.5 to 6.1] and the presence of a central venous catheter (OR, 2.2; 95% CI, 1.2 to 4.3). Conclusions: Although the probiotic-associated invasive infections rarely occurred in children, the incidence has increased along with probiotic pressure. Judicious use of probiotics is mandatory, especially in young children with underlying medical conditions and continuous surveillance will be needed to minimize the safety concerns.

• Food Science and Preservation
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• v.19 no.4
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• pp.470-476
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• 2012

Enzymatic action and microbial growth degrade the quality of fresh-cut lettuce. Browning, a bad smell, and softening during storage are the major forms of quality deterioration. Health-oriented consumers tend to avoid foods treated with chemicals to maintain their freshness. This study was conducted to evaluate the change in the quality of fresh-cut lettuce with combined low-temperature blanching (LB) and ultrasonication (US). The optimum condition was selected using the response surface methodology (RSM), through a regression analysis with the following independent variables; the ultrasonication time (X1), blanching temperature (X2), blanching time (X3), and dependent variable; ${\Delta}E$ value (y). It was found that the condition with the lowest ${\Delta}E$ value occurred with combined 90s US and $45^{\circ}C$ 90s LB (US+LB). The combined treatment group (US+LB) was stored at $10^{\circ}C$ for 9 days with the control group and each single-treatment group, with low-temperature blanching and ultrasonication. Overall, the US+LB group had a significantly high $L^*$ value, which indicates significantly low $a^*$, $b^*$, ${\Delta}E$, browning index, PPO, and POD activity values, and a low total bacteria count (p < 0.05). The US+LB group also had the highest sensory score (except for aroma and texture; p > 0.05).

• 한국노년학
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• v.38 no.3
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• pp.569-592
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• 2018

This study purported to investigate the current state of human rights of older adults residing in rural areas of Korea. The study utilized, as an analytic framework, 4 priority directions (1. "older persons and development", 2. "rural area development", 3. "advancing health and well-being into old age", and 4. "ensuring enabling and supportive environments") with 13 task actions recommended by Madrid International Plan of Action on Ageing (MIPAA). Furthermore, the study examined gender differences in all items included in the analytic framework. Data was collected by the face-to-face survey on 800 subjects aged 65 and over. Statistical analyses were conducted using STATA 13.0 program. The main results were summarized in order of 4 priority directions as follows. First, average working hours per day were 6.2, and men reportedly participated in economic activities and needed job training more than women, while women participated in lifelong education programs more than men. Awareness of fire and disaster prevention facilities was low in both genders. Second, accessibility to the support center for the elderly living alone as well as protective services for the vulnerable elderly was found to be low. IT-based services and networking were used more by men than women, and specifically, IT-based financial transactions and welfare services were least used. Third, medical check-ups and vaccinations were well received, while consistent treatments for chronic illnesses and long-term care services were relatively less given. In addition, accessibility to mental health service centers was considerably low. Fourth, although old house structures and the lack of convenience facilities were found to be circumstantial risk factors for these elders, experiences of receiving housing support services were scarce. The elderly were found to rely more on informal care, and concerns for their care were higher in women than men. Plus, accessibility to elderly abuse services was markedly low. Based on these results, discussed were implications for implementing policies and practical interventions to raise the levels of the human rights for this population.

• Journal of the Korean Institute of Landscape Architecture
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• v.48 no.6
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• pp.1-15
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• 2020

The purpose of this study is to propose a direction for designing and managing a smart park for realizing a smart green city and to present measures in the landscape field to foster related industries. The research process is as follows. First, the concept of a smart park was operationally defined through a literature review, and three principles to be considered in the process of creation and management were established. Second, in terms of the three principles, problems and implications for improvement were derived through an analysis of established cases of smart parks in new and pre-existing cities. Third, a pool of designs and management standards for each spatial component of a smart park was prepared through literature and case studies, and then further refined through brainstorming with experts in related fields. Fourth, measures were suggested to the government, local governments, and the landscape field to promote smart park creation and management. The main findings are as follows. First, the concept of a smart park is defined as "a park that contributes to securing the social, economic, and environmental sustainability of cities and local communities by supporting citizens' safe and pleasant use of parks and improving the management and operational efficiency by utilizing the digital, environment, and material technologies." Second, the three principles of smart parks are to improve the intrinsic value of parks, to improve the innovative functions of parks to solve urban problems, and to make the design, construction, and management process smart. Third, improvement implications were derived through the analysis of cases of smart parks creation in new and pre-existing cities. Fourth, the directions for smart park design and management were suggested in five aspects: green area, hydroponic facility area, road and plaza area, landscape facilities area, and park design method. Fifth, as for policy implications for revitalizing the construction and management of smart parks, the development of smart park policy business models by city growth stage, and park type, the promotion of pilot projects, the promotion of smart park projects in connection with the Korean New Deal policy, and smart park policies led by landscape experts were presented.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.28 no.1
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• pp.39-46
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• 2010

Sounding data is the essential source for the safety of ships navigation system, and fundamental to the reasonable usage and maintenance of the ocean as well. As IT tech, positioning equipment such as GPS and INS, echo sounder are developed, recently, the precise submarine topography database bas been built by Multi-Beam Echo Sounder. However, MBES data includes some inevitable error caused by several factor, and some data have errors where the terrain is wobble. The error, which causes the $moir\acute{e}$ pattern error is the main factor hindering the accuracy of MBES data results, and therefore it is necessary to figure out the main cause of the error for the improvement of the accuracy by removing error data. On this research, the main cause of the error data is studied by analyzing motion sensor value of data including the $moir\acute{e}$ pattern error. Thus, as the result of examination, it turns out that the $moir\acute{e}$ pattern error is related to the standard deviation of Roll, and error data values are results of the non-correspondence between Swath data and Roll values caused by the drastic change of Roll values. Accordingly, the error data is removed by comparing between the gradient of Swath data and Roll values. Finally, as the result of removing error data, it is expected to be able to estimate the quality of MBES using the standard deviation of Motion sensor's Roll value, and calculate the additive error factor, which minimize non-corresponding data, and also this research must be contributed to improve the accuracy of sounding for small vessels with lots of motion in the bad circumstance for navigation.

• Journal of Navigation and Port Research
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• v.38 no.4
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• pp.379-384
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• 2014

In case of sunken tankers, remaining-oil recovery operation should be conducted due to possible oil spill accident. However, the deep sea operation make difficulties in checking the completion of remaining oil recovery process, therefore the work termination procedure is very important. In this paper, a reasonable work termination procedure through the comparison and analysis of two cases(Youil No.1 and Osung No.3, Kyung-Shin) which were performed in different method, using disparate equipment. By investigating previously applied methods and techniques, work speed, safety and expenses were compared. The proposed ending procedure of the remaining-oil recovery project is to recover the remaining oil from each cargo tanks and to clean up such tanks whilst an independent surveyor proceeds to a confirmation procedure whereby said surveyor checks out whether any remaining oil exists by putting a stick in each cleaned up tanks and opening up the hatch cover of the tanks or the top place of the tanks to confirm the cleanness of oil. Such procedure shall be done through discussion by the ordering party, contractor and the independent surveyor all together with a flexible application.

• Applied Chemistry for Engineering
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• v.21 no.6
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• pp.593-602
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• 2010

Chitosan as a natural polymer has superior physicochemical properties such as biocompatibility, biodegradability and nontoxicity, but application of chitosan for therapy of cancer and gene related-disease has been limited by poor solubility in aqueous solution. Therefore, low molecular weight water-soluble chitosan (LMWSC) with high reactivity and strong positive charge can be applied as a delivery system having function to carry in the specific tissue the bioactive material like poor solubility drug, or therapeutic gene and developed as a therapeutic system having good therapeutic efficiency. The most important factor for therapy of various diseases is to reveal the antigen or receptor expressed in specific lesion tissue and the antibody and ligand which can bind with antigen is to introduce at the biomaterials for enhancement the therapeutic efficiency. The studies for cationic synthetic polymer as drug or gene delivery have been actively performed, but it has many problems such as toxicity in the body, therapeutic efficiency. From this point of view, this article demonstrated the introduction of functional groups to target the specific tissue and therapeutic strategy using the modification of LMWSC with free-amine group. The development of these delivery system will provide a positive vision for cancer therapy.

• Journal of the Korean Geotechnical Society
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• v.36 no.11
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• pp.119-133
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• 2020

Underground utility tunnel, the most representative cut and cover structure, is subjected to seismic force by displacement of the surrounding soil. In 2020, Korea Infrastructure Safety Corporation has published "Seismic Performance Evaluation Guideline for Existing Utility Tunnel." This paper introduces two seismic evaluation methods, RDM (Response Displacement Method) and RHA (Response History Analysis) adopted in the guide and compares the methods for an example of an existing utility tunnel. The test tunnel had been constructed in 1988 and seismic design was not considered. RDM is performed by single and double cosine methods based on the velocity response spectrum at the base rock. RHA is performed by finite difference analysis that is able to consider nonlinear behavior of soil and structure together in two-dimensional plane strain condition. The utility tunnel shows elastic behavior for RDM, but shows plastic hinge for RHA under the collapse prevention level earthquake.

• Journal of the Korea institute for structural maintenance and inspection
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• v.21 no.2
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• pp.130-137
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• 2017

Due to the economic growth and development of construction technology, a role of foundation to resist heavy loads has been increased. In this present study to improve the structural performance of reinforced concrete pile, the precast HPC pile reinforced with rebar and filling concrete was developed and the strength of pile was predicted based on the limit state design method. The safety of HPC pile strength was evaluated by comparing with the design values. The geometry of HPC pile is a decagon cross section with a maximum width of 500 mm and a minimum width of 475 mm, and the hollow head of pile thickness is 70 mm. The inner area of the hollow head part was made as the square ribbed shape presented in the limit state design code in order to achieve horizontal shear strength between pile concrete and filling concrete. From the shear test results, it was found that the stable shear strength were secured without abrupt failure until maximum load stage despite the shear cracks was found. Shear strength is 135% and 119% higher than that of design value calculated from limit state design code. The driving test results of HPC pile according to the presence of additional reinforcement showed the outstanding crack resistance against impact loads condition. From the bending test results the flexural load between PHC pile and HPC pile was 1.51 times and 1.48 times higher than that of the design flexural load of conventional PHC pile.

• Journal of Satellite, Information and Communications
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• v.9 no.3
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• pp.1-4
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• 2014

A radio communication system has interference caused by other radio transmitters operated in co-channel or adjacent channels. Therefore technical specifications are made by considering and investigating the effects of interference between the new system and present systems when the new system will be started to serve in the near future. FTS is used for preventing an abnormal mission and guaranteeing public protection. Recently the next generation FTS's are researched to reinforce the security and to increase the operating capability of simultaneous use. EFTS known as one of the next generation FTS's is suitable for such purposes. In this paper the effects of interference signals on the performance of EFTS are investigated. Noncoherent DPSK and noncoherent CPFSK are considered for the modulation method of EFTS and a FMCW and a pulse RADAR considered as a interferer. The power of FMCW is 20.3dB lower than the power of EFTS and the power of pulse RADAR is 19.1dB lower than that of EFTS. Simulation results show that FMCW interferer reduce $E_b/N_o$ of about 1dB and $E_b/N_o$ of EFTS deteriorates about 0.5dB due to interference signals generated from pulse RADAR.