• Tuberculosis and Respiratory Diseases
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• v.45 no.1
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• pp.153-168
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• 1998

Background: The existing data indicate that obstructive sleep apnea syndrome contributes to the development of cardiovascular dysfunction such as systemic hypertension and cardiac arrhythmias, and the cardiovascular dysfunction has a major effect on high long-term mortality rate in obstructive sleep apnea syndrome patients. To a large extent the various studies have helped to clarify the pathophysiology of obstructive sleep apnea, but many basic questions still remain unanswered. Methods: In this study, the influence of obstructive sleep apnea on systemic blood pressure, cardiac rhythm and urinary catecholamines concentration was evaluated. Over-night polysomnography, 24-hour ambulatory blood pressure and ECG monitoring, and measurement of urinary catecholamines, norepinephrine (UNE) and epinephrine (UEP), during waking and sleep were undertaken in obstructive sleep apnea syndrome patients group (OSAS, n=29) and control group (Control, n=25). Results: 1) In OSAS and Control, UNE and UEP concentrations during sleep were significantly lower than during waking (P<0.01). In UNE concentrations during sleep, OSAS showed higher levels compare to Control (P<0.05). 2) In OSAS, there was a increasing tendency of the number of non-dipper of nocturnal blood pressure compare to Control (P=0.089). 3) In both group (n=54), mean systolic blood pressure during waking and sleep showed significant correlation with polysomnographic data including apnea index (AI), apnea-hypopnea index (AHI), arterial oxygen saturation nadir ($SaO_2$ nadir) and degree of oxygen desaturation (DOD). And UNE concentrations during sleep were correlated with AI, AHI, $SaO_2$ nadir, DOD and mean diastolic blood pressure during sleep. 4) In OSAS with AI>20 (n==14), there was a significant difference of heart rates before, during and after apneic events (P<0.01), and these changes of heart rates were correlated with the duration of apnea (P<0.01). The difference of heart rates between apneic and postapneic period (${\Delta}HR$) was significantly correlated with the difference of arterial oxygen saturation between before and after apneic event (${\Delta}SaO_2$) (r=0.223, P<0.001). 5) There was no significant difference in the incidence of cardiac arrhythmias between OSAS and Control In Control, the incidence of ventricular ectopy during sleep was significantly lower than during waking. But in OSAS, there was no difference between during waking and sleep. Conclusion : These results suggested that recurrent hypoxia and arousals from sleep in patients with obstructive sleep apnea syndrome may increase sympathetic nervous system activity, and recurrent hypoxia and increased sympathetic nervous system activity could contribute to the development of cardiovascular dysfunction including the changes of systemic blood pressure and cardiac function.

• Tuberculosis and Respiratory Diseases
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• v.52 no.1
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• pp.24-36
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• 2002

Background: Bronchial reactivity is known to be a component of airway hyperresponsiveness, a cardinal feature of asthma, with bronchial sensitivity, and is increments in response to induced doses of bronchoconstrictors as manifested by the steepest slope of the dose-response curve. However, there is some controversy regarding methods of measuring bronchial reactivity and clinical impact of such measurements. The purpose of this study was to evaluate the clinical significance and assess the clinical use by analyzing the relationship of the bronchial sensitivity, the clinical severity and the changes in pulmonary function with bronchial reactivity. Method: A total of 116 subjects underwent a methacholine bronchial provocation test. They were divided into 3 groups : mild intermittent, mild persistent, moderate and cough asthma. Severe patients were excluded. Methacholine PC20 was determined from the log dose-response curve and PC40 was determined by one more dose inhalation after PC20. The steepest slope of log dose-response curve, connecting PC20 with PC40, was used to calculate the bronchial reactivity. Body plethysmography and a single breath for the DLCO were done in 43 subjects before and after methacholine test. Results: The average bronchial reactivity was 38.0 in the mild intermittent group, 49.8 in the mild persistent group, 61.0 in the moderate group, and 41.1 in the cough asthma group. There was a weak negative correlation between PC20 and bronchial reactivity. A heightened bronchial reactivity tends to produce an increased clinical severity in patients with a similar bronchial sensitivity and basal spirometric pulmonary function. There were significant correlations between the bronchial reactivity and the initial pulmonary function before the methacholine test in the order of sGaw, Raw, $FEV_1$/FVC, MMFR. There were no correlations between the bronchial sensitivity and the % change in the pulmonary function parameters after the methacholine test. However, there were significant correlations between the bronchial reactivity and the PEF, $FEV_1$, DLCO. Conclusion: There was weak significant negative correlation between the bronchial reactivity and the bronchial sensitivity, and the bronchial reactivity closely reflected the severity of the asthma. Accordingly, measuring both the bronchial sensitivity and the bronchial reactivity can be of assistance in assessing of the ongoing disease severity and in monitoring the effect of therapy.

• Journal of Adhesion and Interface
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• v.11 no.4
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• pp.162-167
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• 2010

In the present work, the effect of electron beam irradiation on the chemical and thermal characteristics of cellulose-based jute fibers was explored by means of chemical analysis, electron spin resonance analysis, ATR-FTIR spectroscopy, thermogravimetric analysis and thermomechanical analysis. Jute fiber bundles were uniformly irradiated in the range of 2~100 kGy by a continuous method using a conveyor cartin an electron beam tunnel. Electron beam treatment, which is a physical approach to change the surfaces, more or less changed the chemical composition of jute fibers. It was also found that the radicals on the jute fibers can be increasingly formed with increasing electron beam intensity. However, the electron beam irradiation did not change significantly the chemical functional groups existing on the jute fiber surfaces. The electron beam irradiation influenced the thermal stability and thermal shrinkage/expansion behavior and the behavior depended on the electron beam intensity.

• 한국신재생에너지학회:학술대회논문집
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• 2010.06a
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• pp.107.1-107.1
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• 2010

고체 흡수제를 이용한 석탄합성가스 중의 황제거 기술은 습식 스크러빙 방식에 비해 고온에서 운전가능하므로 석탄가스화복합발전의 효율 향상을 가져올 수 있다. 고체탈황제는 서로 연결된 두 개의 유동층 반응기를 순환하면서 흡수탑에서는 합성가스 중의 $H_2S$로부터 황을 흡수하고 재생탑에서는 공기 중의 산소와 흡수된 황이 반응하여 $SO_2$를 배출하고 재생된다. 따라서 고체 황 흡수제는 유동층 공정에 응용가능한 물성과 함께 높은 황흡수능과 빠른 반응성이 요구된다. 본 연구에서는 기존 개발된 고체 탈황제가 가졌던 소성시 수축 현상, 낮은 내마모도 등을 개선하기 위해 지지체 조성을 변경하여 개발한 분무성형 탈황제의 흡수 재생 온도에 따른 황흡수 특성 변화를 조사하였다. $H_2S$ 1 vol. %를 함유한 모사 합성가스를 이용하여 흡수온도 450, $500^{\circ}C$, 재생온도 500, 550, 600, $650^{\circ}C$에서 황 흡수능을 열중량분석기를 이용하여 측정하였다. 개발된 흡수제는 유동층 공정 적용에 적합한 훌륭한 물성(형상, 밀도, 강도 등)과 함께 $500^{\circ}C$ 흡수와 $650^{\circ}C$ 재생을 기준으로 10 wt% 이상의 높은 황흡수능을 보여주었다. 흡수온도 변화는 황 흡수능 변화에 큰 영향을 미치지 않았으나, 재생온도가 $600^{\circ}C$ 이하인 경우 황흡수능이 5 wt% 이하로 크게 떨어져 재생온도를 $650^{\circ}C$ 이상 유지시키는 것이 중요함을 알 수 있었다.

• Journal of the Korea Convergence Society
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• v.6 no.1
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• pp.7-16
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• 2015

A segmentation process extracts an interesting area of barcode in an image and gives a crucial impart on the performance of barcode verifier. Previous segmentation methods occurs some issues as follows. First, it is very hard to determine a threshold of length in Hough Line transform because it is sensitive. Second, Morphology transform delays the process when you conduct dilation and erosion operations during the image extraction. Therefore, we proposes a novel Converged Harris Corner detection-based segmentation method to detect an interesting area of barcode in Data Matrix. In order to evaluate the performance of proposed method, we conduct experiments by a dataset of barcode in accordance with size and location in an image. In result, our method solves the problems of delay and surrounding environments, threshold setting, and extracts the barcode area 100% from test images.

• Korean Journal of Human Ecology
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• v.19 no.3
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• pp.577-588
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• 2010

This study was conducted to investigate the changes in alcohol consumption of male university students in Daegu, Korea and their drink-related behavior. The study focused on these changes over a decade using self-administered questionnaire surveys and health examinations that were carried out at a university campus in 1999 and in 2009. In both years more than 85% of students responded that they drank alcohol. However, significant increases in the frequency and amount of alcohol consumption were found (p<.001). The main influence on students' drinking behavior was friends/peers in both years. The most frequently preferred alcohol of respondents was so-ju (a traditional Korean liquor) in both years. However, the most frequently preferred type of food to accompany drinking had significantly changed (p<.01). Other changes including the increase of drinking speed and smoking during drinking were found to have significantly changed (p<.05) while significant difference regarding the decrease in food intake during drinking was not found. No significant difference in the amount of alcohol consumed was noted between underage drinkers and drinkers of above the legal drinking age. Heavy drinkers in the 2009 population had significantly higher systolic blood pressure than non-drinkers and moderate drinkers (p<.01). This study also indicates that there may be a rise in heavy drinking and/or binge drinking among drinkers including underage students. The results of this study suggest that alcohol-blood pressure associations are considered to be of concern even in young adults. This study also suggests the need for special alcohol prevention programs or campaigns to intervene in the behavior of students.

• Journal of the Korean Ceramic Society
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• v.39 no.3
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• pp.265-271
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• 2002

Density, water resistance, Raman and infrared spectroscopy were used to investigate the change of structural characteristics with the composition of phosphate galss samples made by melting method. The structural abnormality of the density and water resistance were rapidly increased and shown near the 60mol% of $P_2O_5$. This result could be explained by the structural changes owing to the strong shrinkage of glass network by the coordination of DBO(Double-Bonded Oxygen) around $Mg^{2+}$ cations. In addition, it seems that the DBOs coordinating $Mg^{2+}$ cations lose its characteristics of double bonding and resonate with other NBOs(Non-Bonding Oxygen).

• Proceedings of the Korean Society of Medical Physics Conference
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• 2003.09a
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• pp.79-79
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• 2003

심실의 내부는 유두근이나 trabecular와 같은 해부학적 구조물들로 인해 복잡한 형태를 띄고 있다. 그러한 복잡한 구조는 MR 영상을 이용한 심박출량 측정시 오차를 유발시킬 수 있으며, 만약 오차를 줄이기 위해 수작업을 하게 된다면 많은 수고와 시간이 필요하게 될 것이다. 본 연구에서는 threshold 기법을 이용하여 짧은 시간동안에 정확하게 복잡한 구조를 가진 심실의 심박출량을 측정하고자 하였다. 7 명의 환자에 대해 l.5T 급 MR 장치 (INTERA, Philips, Netherlands)를 이용하여 short-axis cardiac MR 영상을 획득하였다. 한 환자에 대해서 8개에서 10개의 슬라이스 영상을 8-10 mm의 두께로, 하나의 심장주기(cardiac cycle)동안 일정한 시간간격으로 25 개의 영상을 획득하였으며, 펄스시퀀스로는 ECG-gated segmented balanced fast field echo (TR/TE = 3ms/1.56ms)를 사용하였다. 획득된 영상은 PC(threshold 기법)와 workstation (기존의 수동 및 자동 segmentation 기법)로 DICOM 형태로 전송되었다. 측정은 IDL을 이용하여 자체 제작된 소프트웨어와 상용화된 소프트웨어 (MASS 5.0, MEDIS, Netherlands)를 이용하여 분석되었다. MR 영상에서 심내벽 부위를 추출하기 위하여 자체제작된 소프트웨어로는 threshold 기법을, 상용 소프트웨어로는 기존의 수동 및 자동 기법을 이용하였다. 심박출량은 최대수축기와 이완기 사이의 용적 차이로써 계산되었으며, 좌심실 및 우심실 모두에 대해 수행되었다. 또한, 해부학적 구조의 복잡도에 따른 측정방법의 정확도를 확인하기 위해 유두근 및 trabecular의 hypertrophy의 정도를 3 단계로 구분하고 측정된 값들을 통계적으로 분석하였다. Hypertrophy가 약한 그룹에서는 기존의 수동방식과 threshold 기법간의 의미있는 차이가 없었으며 (p=0.372), 기존의 수동 및 자동방식 간에도 큰 차이가 없었다 (p=0.298). 그러나, hypertrophy가 심한 그룹에서는 수동방식 및 자동방식 측정치 사이에 통계적으로 유의한 차이를 보임을 알 수 있었다 (p=0.044). 그러나, threshold 기법과 수동방식 사이에는 유의한 차이가 없었다 (p=0.l94). 분석시간은 threshold 기법이 기존의 수동방식에 비해서 두배정도 빠르다는 것을 알 수 있었다, Threshold 기법은 심박출량 측정에 있어서 정확하면서도 빠른 결과의 도출이 가능했으며, 특히 심내벽의 구조가 복잡한 경우에 그 효과가 증대됨을 알 수 있었다.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.11
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• pp.1273-1281
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• 2014

Tissue engineering is an emerging research field that has the potential to restore, regenerate and repair damaged bone tissue and organs. Tricalcium phosphate and hydroxyapatite biomaterials-based calcium phosphate are excellent materials that have both osteoconduction and biocompatibility for bone tissue regeneration. In this study, solution structures were successfully fabricated using a fused deposition modeling system based on deposition and heating devices. The morphology characteristics of the bioceramic scaffolds sintered at a temperature of $1,300^{\circ}C$ were analyzed by scanning electron microscopy. The effects of various blended TCP/HA ratio on the microstructure and shrinkage were studied. The mechanical properties of the scaffolds were measured using a compression testing machine from stress-strain curves on the crosshead velocity of 1 mm/min. The fabricated scaffolds were evaluated by cell proliferation tests of MG-63 cells. The results of this study suggest that the blended TCP(75 wt%)/HA(25 wt%) scaffold is an appropriate scaffold for bone tissue regeneration.

• Korean Journal of Remote Sensing
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• v.30 no.6
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• pp.719-730
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• 2014

Small BAseline Subset (SBAS) technique using multi master interferograms can be effective to detect surface deformation in forest area. In this paper, The analysis reveals area of 2-dimension surface deformation at Seguam Island in Aleutian Arc., Alaska. We acquired ERS-1/2 data from track 201 and 473 datasets on Seguam Island from 1992 to 2008. This study analyze surface deformation applying Differential Interferometry Synthetic Aperture Radar (DInSAR) and SBAS time series method using two adjacent tracks. As a results, it was calculated that subsidence -1~2 cm in LOS direction and - 2~3 cm in vertical direction. The horizontal direction was repeated contraction and expansion. The observation of 2-dimension displacements explained the volcanic activity on Seguam island. Also, it is believed to be used for basic data to estimate movements of magma source.