• Journal of Nutrition and Health
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• v.49 no.5
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• pp.313-322
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• 2016

Purpose: This study was conducted to examine the relationship among cognitive function, nutrition screening initiative (NSI) score, and food intake status. Methods: A total of 409 subjects aged over 60 years were recruited from the Yongin dementia prevention and control center. Mini Mental State Examination Dementia Screening (MMSE-DS) method was used to assess the cognitive function of the subjects. Information on health related behaviors and food intake was collected by face to face interview using a structured questionnaire. The questionnaires included the NSI DETERMINE checklist, food intake sheets by 24 hr recall method and by semi-quantified food frequency questionnaire. Results: Subjects were divided into low cognitive or normal groups according to the MMSE-DS result. The prevalence of low cognitive function in the subjects was 25.7%. The low cognitive group exercised less and had higher nutritional health risk than the normal group. The low cognitive group had lower consumption of polyunsaturated fatty acid and higher tendency of thiamin, riboflavin, and iron deficiency. The low cognitive group had less frequency of eating mackerel, pepper, tangerine, and watermelon and higher frequency of eating white rice and cookies than the normal group. Conclusion: The results of this study imply that the cognitive function of elderly is related to exercise behavior, nutritional health risk, and food and nutrient intake status.

• Sleep Medicine and Psychophysiology
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• v.3 no.1
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• pp.68-78
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• 1996

Objective : The Mini-Mental State Examination(MMSE) and Brief Cognitive Rating Scale(BCRS) are frequently using screening tests fur evaluating the cognitive function in clinical practice and research. The authors tried to evaluate the clinical usefulness of these tests for the patients with non-traumatic subcortical cerebrovascular disease. Method : We administered the MMSE and BCRS to 85 patients and 195 normal control group. In order to compare the test results according to the lesion site, we divided patients into left sided lesion group(21 patients), right sided lesion group(31 patients) and both sided lesion group(13 patients). Their cognitive function was evaluated by the BNA and daily living functional activity was examined by the IADLs(Instrumental Activities of Daily Living Scale)and GERRI(Geriatric Evaluation by Relative's Rating Instrument). Results : The results are as follows : 1) In the BNA, the patients scored significantly lower than control group at all items(except Right-Left Orientation and Motor Impersistence), but there were no difference in the MMSE(total score and all 5 items), and only 2 items(recent memory and self-care) were significantly different between two groups in the BCRS. 2) In the comparison by lateralization, there were significant differences among three groups at 3 items(Left Tactile Form Perception, Left Finger Localization and Right Finger Localization) in the BNA. But, there were no difference in the MMSE and BCRS. 3) In the correlation between daily living functioning and the MMSE/BCRS, control group showed no relation(except item of cognitive functioning), but patient group was significantly correlated with 3 items(social functioning, instrumental activities of daily living and cognitive functioning). Conclusions : These findings suggest that MMSE and BCRS are not useful as the test for cognitive function and discrimination of lateralization in patients with non-traumatic subcortical cerebrovascular disease. However, scores of these tests may be related with the functional level(such as daily living function) of patients.

• Proceedings of the ESK Conference
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• 1997.10a
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• pp.244-245
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• 1997

후각장애를 가져오는 질환에는 비, 부비동 질환, 두부외상, 상기도 감염, 간질 및 노인성치매 등의 신 경게 질환, 칼만증후군과 같은 대사성 질환 등이 있으나, 현실적으로 후각장애의 정도를 측정하기가 쉽 지않고, 후각역치가 개인간에 차이가 많아 아직 연구가 미진한 상태이다. 특히 교통사고나 산업현장에서 쉽게 접할 수 있는 두부외상이나 독성화학물질 등에 의해 후각장애가 많이 나타나고 있으나 아직 보상의 기준이 없어 환자들이 어려움을 겪고 있다. 두부손상 후에 발생하는 후각장애는 병원에서도 놓치기 쉬우며, 알아내더라도 두렷한 치료방법이 없기 때문에 간과되어온 것이사실이다. 그러나, 이런 후각장애 환자들은 집안에서 가스가 새는 것을 느끼지 못하며, 화재로연기가 나더라도 알아차리지 못하고, 음식이 상해도 잘 모르므로 위험에 빠지기가 쉽고, 후각에 이상이 있으면 자연적으로미각도 감소하므로 식욕도 떨어지고, 때로는 우울증에 빠지기도하며, 주부의 경우에는 음식을 만들기가 어렵게 된다. 두부외상을 받은 전체 환자 의 약5 -10%에서 후각장애가 나타나는 것으로 알려져 있으나, 냄새가 나지만 정확히 무슨 냄새인지 이름을 대지 못하거나 어떤 냄새를 다른 냄새와 감별하지 못하는 경우까지 합하면 대개 20-30%로 생각된다. 두부 손상 후의 후각장애의 정도는 얼마나 크게다쳤는 가에 달려있지만, 조금 다치더라도 후각장애가 심한 경우도 있다.

• Therapeutic Science for Rehabilitation
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• v.10 no.3
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• pp.43-56
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• 2021

Objective : The objective of this study was to present the components of frailty by organizing the definitions of frail elderly and analyzing the tools used to screen them. Methods : This study searched for articles at involved frailty screening assessments in the elderly. Databases including CINAHL, Embase, Medline Complete, and PubMed were searched. The search terms were "assess" AND "frailty" AND "screening" AND ("frail elderly" OR "elderly"). Results : A total of 539 articles were identified by the search and 11 articles were selected. Frailty occurs due to the depressed function of multidimensional factors, and a frail elderly person is defined as one at high risk of health degeneration, functional impairment, and occurrence of disability, and having a high level of threat to life. Seven tools were selected from 11 articles. The most frequently used tool was the frailty phenotype, which was used in five articles (45.4%). The identified components of frailty were physical, activity participation, nutrition, psychological, social, overall health, and age. Conclusion : The results confirmed the definition and components of frailty. This study is expected to contribute to the future development of standardized evaluation tools for screening frail elderly individuals and intervention programs for the management of the frail elderly.

• Science of Emotion and Sensibility
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• v.12 no.1
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• pp.11-18
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• 2009

The purpose of this study was, first, to extract the risk factor by investigating several cases of accident of senile dementia patient at home, and second, based on these results to provide basic information for the determination of monitoring factor for the care of senile dementia patient. Basic and behavioral characteristics, Short form of Samsung Dementia Questionnaire (S-SDQ), Activities of Daily Living (ADL), and cases of accident were investigated with 55 senile dementia patient at home (16 male, 39 female). Based on these questionnaires, risk factors were extracted and frequency, cooccurrence frequency, and occurring place of risk factors, presence or not, region, and degree of injury were investigated. Frequency between risk factors and behavioral characteristics, ADL, and S-SDQ was analyzed by crosstabulation frequency analysis. Results showed that 12 risk factors were extracted, and the frequency of 'going out' was the highest, and risk factors for injury were 'tumble', 'bump', 'slip', and 'fall'. Cooccurrence frequency analysis showed that the occurrence of 'fall', 'going out', 'fire of gas', and 'violence' with other factors was relatively higher than others. The occurring place of risk factor was the highest in home neighborhood, and the region of injury in knee, and the degree of injury with bruise. Crosstabulation frequency analysis showed that factors which had difference in frequency of risk factor were behavioral disorder, disorder of daily living and ADL. Factor which had difference in frequency due to the degree of behavioral disorder and disorder of daily living was 'going out', and factors which had difference in frequency due to the degree of ADL were 'slip' and 'fire of gas'.

• Korean Journal of Cognitive Science
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• v.20 no.1
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• pp.79-107
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• 2009

Episodic memory, i.e. memorization of information within a spatiotemporal environment, is affected Alzheimer's disease(AD), but its impairment may also be occurred in the normal aging process. The purpose of this study is to analyze and evaluate memory in with Dementia of Alzheimer Type by examining their cognitive skills in episodic memory using the technique. This new method involves assessing the mental images the subject's own past in the mind like projected and movies. Three patients in the early stage of Dementia of Alzheimer Type, one with mild depression, and 2 healthy controls for comparison were asked to retrieve their episodic memory of the previous day, week, month, and a day testing day. The answers were then analyzed with regards to their specific features as emotional state, color, and time order. In the following day, the subjects were tasked to recall again the images they reproduced in the day's test order to observe of memory. Results showed that all 3 patients failed to arrange the retrieved images in time order and their images of the previous day were unclear in color and were stationary like photographs, even when they reproduced the mental images at much quantity as controls. patients could not remember particular events of yesterday, and only recalled the general occurrences of every day life. These results suggest that in the early stage of Dementia of Alzheimer Type, difficulties in the retrieval of recent episodic memory begin to primarily occur, and qualitative impairment happens earlier than quantitative.

• Journal of Life Science
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• v.18 no.3
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• pp.344-349
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• 2008

Normal somatic cells proliferate for a limited number of doublings in culture and then enter an irreversible growth-arrest state called replicative senescence. Replicative senescence has been believed a reason for the limited cellular turnover and deterioration of tissue function in aged animals. However, there is no experimental evidence supporting this assumption. Furthermore, cells from aged person have been poorly characterized with an exception of the cases of T cells. In this study, we examined cell biological changes occurring in replicative senescence of fibroblast strains originated from a new-born (NHF-NB) and a 87 year old man (NHF-87). NHF-87 (and the cells from a 75-year old) proliferated to smaller population doublings and with longer doubling times than NHF-NB did. At early passages, NHF-87 exhibited a low senescence-associated ${\beta}-Gal$ (SA ${\beta}-Gal$) activity and lipofuscin level, typical markers for cellular senescence. Furthermore, they maintained low levels of lysosome and reactive oxygen species (ROS). All of these levels increased dramatically in the late passage NHF-87 quite similarly as those in the late passaged NHF-NB did. These results indicate that most cells originated from the aged maintain a phenotype of the cells originated from new-born donors and undergo replicative senescence with the same kinetics as that of the cells from new-born. It is also indicated that not SA ${\beta}-gal$ activity but cell proliferation rate may be qualified as a biomarker for cells aged in vivo.

• Korean Journal of Social Welfare Studies
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• v.44 no.2
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• pp.327-358
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• 2013

This study aimed to analyze the trajectories of cognitive function and functional disability, and to identify the impacts of socio-demographic factors on the two variables. Based on the assumption that there are differences according to the progress of cognitive impairment, it focused on examining the differences in trajectories of cognitive function and functional disability between two groups: dementia conversion group and dementia non-conversion group among cognitively normal older adults. This study was conducted based on the data from a 3-wave panel study of a sample of 966 Yeoncheon elderly cohort aged 65 and over between 1997 and 2003. Latent growth curve model and multi-group structural equation modeling were used to examine the hypothesis. Results revealed that dementia conversion group exhibited faster rate of cognitive decline as well as lower initial cognitive level. Difference between two groups was not significant in the initial level of functional disability, yet dementia conversion group showed greater degree of deterioration in the functional disability over time than dementia non-conversion group did. In terms of the influence of socio-demographic factors on cognitive function and functional disability, the cognitive decline was more drastic in the female group, whereas functional decline was more apparent for the male group. The level of education in early life had a strong impact on the cognitive function in later life. Based on these findings, practical implication for high risk groups in cognitive function and functional disability were discussed.

• Journal of Science and Technology Studies
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• v.2 no.2 s.4
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• pp.145-189
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• 2002

This paper explores into the potential contribution of welfare science and technology(WST) to meeting the challenges of ageing. Drawing on the literature about gerontechnology, this paper considers the application of scientific knowledge for welfare of an aging population. WST for the improvement of the daily functioning of the elderly people can not only prevent, delay or compensate for the declines or impairments of coginitive and physical functions (by assistive technology) but also enhance personal ability to overcome problems either by supporting the person's abilities (by supportive technology) or by changing the environment (by public welfare technology). This paper draws attention to a paradigm change in the conceptualization of disability and its ramifications for the role of technology and aging. A range of approaches such as Barrier-Free design, Universal Design points to new directions of WST in which products and services are devised to improve the quality of life for all people, and hence enhancing the socio-economic vitality. It is suggested that the future of welfare science and technology will be based in large measure on its goal to reduce or prevent individual and structural lag in the relationships between people and their environments. Addressing issues of the broader physical and social environment will emphasize the goal of prevention and the view that environmental needs for aging population are changing over time.

• The Journal of the Korea Contents Association
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• v.14 no.11
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• pp.328-336
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• 2014

This work has performed to find what activities of daily living are required for the intensive interests when inpatient elderly more than 3 months has been supported and convalescent care, where the inpatient elderly were judged by the inpatient assessment report in the time of December, 2013. According to the estimation with logistic function of the relationship between the state of decision making recognition technology and the Activities of Daily Living(ADL), the intensive cares for the elderly are required in the parameters of 'Having meal' and 'transferring sitting' when they are severed and convalescently cared as the degree of functional independence for ADL are severly proceeded. In addition, the senescence and disease the activities except 'Having meal' and 'transferring sitting' seem to be influenced by the decline of body function more than the state of decision making recognition technology for daily living.