• Title/Summary/Keyword: 글루타민

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Inhibition Effect of a Few Amino Acids on the Corrosion of Copper in Aerated Artificial Sea Water (공기가 포화된 인공해수에서 몇 가지 아미노산의 구리 부식 억제 효과)

  • Kim, Youn-Kyoo
    • Journal of the Korean Chemical Society
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    • v.54 no.6
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    • pp.680-686
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    • 2010
  • Inhibition effects of alanine(Ala), asparagine(Asn), aspartic acid(Asp), glutamine(Gln) and methionine(Met) on the corrosion of copper were investigated in aerated artificial sea water. Amino acid adsorption process in copper surface can be explained by Temkin logarithmic isotherm due to the interaction between the adsorbed molecules. The inhibition efficiency for the copper corrosion depended on the concentration of amino acids.

Effect of Glutamine on the Diclofenac Induced Bacterial Translocation and Lipid Peroxidation (Diclofenac에 의해 유발된 장내세균전위와 지질과산화에 대한 글루타민의 효과)

  • Kim, Eun-Jeong;Kim, Jeong-Wook
    • YAKHAK HOEJI
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    • v.49 no.2
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    • pp.128-133
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    • 2005
  • The aim of this study was to examine whether administration of glutamine are able to prevent the NSAID induced bacterial translocation and lipid peroxidation in the rats. The an imals with glutamine were fed with L-glutamine for 5 days before diclofenac administration (100 mg/kg orally). 48 hour after diclofenac administration, intestinal permeability, serum biochemical profiles, and malondialdehyde levels of ileum were measured for evaluation of gut damage. Also, enteric aerobic bacterial counts, number of gram-negatives in mesenteric Iymph nodes, liver, spleen and kidney and malondialdehyde levels in liver, spleen, kidney and plasma were measured. Diclofenac caused the gut damage, enteric bacterial overgrowth, increased bacterial translocation and increased lipid peroxidation. Co-administration of glutamine reduced the gut damage, enteric bacterial overgrowth, bacterial translocation and lipid peroxidation induced by diclofenac. This study suggested that glutamine might effectively prevent non-steroidal anti-inflammatory drug induced bacterial translocation and lipid peroxidation in the rat.

Preparation and Stability Measurement of Liposome-amino Acid Conjugates (리포솜-아미노산 결합체의 제조와 안정성 측정)

  • 문제영;이기영;김진철
    • KSBB Journal
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    • v.15 no.1
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    • pp.96-99
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    • 2000
  • Liposome-amino acid conjugates were prepared using phopholipid (dipalmitoylphosphatidylcholine (DPPC) or distearoylph-osphatidylcholine(DSPC)) and hydrophobically modified amino acids (glutamic acid(glu), glutamine(gln) or asparagine(asn)). The size of liposomes was about 100 nm. According to the glucose-induced turbidity changes, liposomes composed of DPPC and glutamic acid have higher glucose binding affinity than liposomes of DPPC-glutamine or DPPC-asparagine. Also, the liposomes were more stable in terms of aggregation or fusion than the others (DPPC-glutamine, DPPC-asparagine and DSPC-amino acids). As a rdsult, stable liposomes with an affinity for glucose could be prepared with DPPC and glutamic acid.

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Dyeing Properties of Cotton Fabrics using Residual Parts of Cultivated Fernbrake (Pteridium aquilinum) (재배고사리 부산물을 활용한 면직물의 염색성)

  • Kang, Eun-Young;Lee, Hye-Sun
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2012.03a
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    • pp.68-68
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    • 2012
  • 고사리는 다년생 양치식물로 예부터 선조들이 즐겨먹던 산채의 일종이다. 고사리에 비타민$B_1,B_2$, C뿐만 아니라 아스파라긴과 글루타민과 같은 성분도 포함된 것으로 밝혀지면서 최근 그 활용가치가 높아지고 있다. 고사리의 재배는 1996년부터 꾸준히 증가하여 현재 1252.8ha(2010년기준)에 이르고 있다. 고사리의 채취는 4월중순 ~ 5월초순에 이르며 어린 순만을 채취하여 식용으로 사용하고 채취시기 후 재배고사리 성채의 줄기와 잎은 50~100cm의 높이로 자라게 내버려두었다가 가을이 되면 저온이나 서리로 인해 갈변하여 일년생을 마치고 있는 실정이다. 이에 본 연구는 재배고사리 채취시기 이후 7,8,9월에 재배고사리 부산물인 줄기와 잎을 채취하여 염액을 추출하고 KS K 0905 표준면직물을 활용하여 농도변이 100%, 200%, 300%, 400%, 500%별로 면직물의 염색성을 살펴보았으며 염색된 직물의 $L^*$, $a^*$, $b^*$값과 먼셀값, K/S값을 분광광도계를 사용하여 측정하였다. 또한 재배고사리 부산물 색소의 특성을 알아보기 위해 추출액을 혼합하여 동결건조하고 분말화한 다음 TLC분석에 의해 그 성분을 확인하였다.

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Effect of Glutamine on the Methotrexate Induced Gut Barrier Damage, Bacterial Translocation and Weight Changes in a Rat Model (백서에서 Methotrexate에 의하여 유발된 장관장벽손상 및 장내세균전위와 중량 변화에 대한 글루타민의 효과)

  • Kim, Eun-Jeong;Kim, Jeong-Wook
    • YAKHAK HOEJI
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    • v.51 no.1
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    • pp.1-6
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    • 2007
  • The aim of this study was to examine whether administration of glutamine are able to prevent the methotrexate induced gut barrier damage, bacterial translocation, and weight changes. The animals with glutamine were fed with L-glutamine (1.2 and 2.4 mg/kg/day) for 7 days before methotrexate administration (20 mg/kg orally). 48 hour after methotrexate administration, intestinal permeability were measured for an assessment of the gut barrier dysfunction. Also, enteric aerobic bacterial counts, number of gram-negatives in mesenteric lymph node (MLN), liver spleen, kidney and heart were measured for an assessment of the enteric bacterial number and bacterial translocation. Amounts of food intake, body weight changes and organ weight changes of liver spleen, kidney and heart were measured. Methotrexate administration caused body and liver weight loss regardless amounts of food intakes. Methotrexate induced increasing intestinal permeability, enteric bacterial undergrowth and bacterial translocation to MLN, liver and spleen, but not kidney and heart. The supplements with glutamine reduced the intestinal permeability bacterial translocation, and not influences enteric bacterial number, and body and liver weight changes. This study suggested that glutamine might effectively reduce methotrexate induced intestinal damage and bacterial translocation, but not influence body and organ weight loss.

Characterization and Distribution of Transferrin from the Last Larval Haemolymph of Papilio xuthus (호랑나비 유충 혈림프 Transferrin의 특성과 분포)

  • Shin, Myung-Ja;Kim, Kyoung-Keun;Kim, Jeong-Sook;Lim, Jae-Hwan;Seo, Eul-Won
    • Journal of Life Science
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    • v.17 no.8 s.88
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    • pp.1046-1052
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    • 2007
  • Transferrin is a molecule carrying iron to store and maintain for iron homeostasis of living organisms. In this study, we have purified transferrin, as an iron-binding protein, from the last larval haemolymph of Papilio xuthus by KBr density gradient ultracentrifugation and gel filtration (superose 6 HR) using fast protein liquid chromatography (FPLC) and transferrin containing iron was identified by Ferene S staining. The purified haemolymph transferrin was shown to have molecular mass of 78 and 80 kDa and amino acid composition of transferrin was rich in aspartic acid, valine, leucine and glutamic acid. With immuno-diffusion assay, we confirmed the existence of the transferrin in the haemo-lymph and fat body by detection of visible and clear positive reaction. From the quantitative comparison by rocket immuno-electrophoresis process, the amount of transferrin were increased in the haemolymph of 3 days after pupation and the whole 5 days after pupation. Here, with biochemical and immunohistochemical analysis, we speculate the relationship of transferrin between the physical characteristics and distribution during metamorphosis of P. xuthus.

Nutritional and Bioactive Compounds of Yellow Cherry Tomato (황색 방울토마토의 영양성분 및 생리활성 물질분석)

  • Choi, Suk-Hyun
    • The Journal of the Korea Contents Association
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    • v.20 no.2
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    • pp.451-461
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    • 2020
  • This study was carried out to investigate the value of yellow cherry tomato as a food material. Contents of nutritional and bioactive compound were determined from yellow cherry tomato. 17 of amino acids occurred. L-Glutamic acid (45.15%), L-glutamine (22%) and L-aspartic acid (11%) were the main amino acids. 8 of essential amino acids were found except tryptophan. γ-aminobutyric acid (GABA) was found in high contentration (258.58 mg/100g). Contents of Lycopene and β-carotene were 2.18 mg/100 g and 9.90 mg/100 g, respectively. Yellow cherry tomato contained naringenin chalcone, quercetin-3-rutinoside(rutin), 5-caffeoylquinic acid, 3-caffeoylquinic acid, and quercetin-3-apiosylrutinoside that have various bioactivities. These results revealed that yellow cherry tomato would be very useful and valuable food material.

Inhibition of Enzymatic Browning of Crown Daisy by Maillard Reaction Products (마이얄반응생성물(Maillard reaction product)에 의한 쑥갓의 효소적갈면 억제)

  • Kim, Ji-Hae;Song, Hyeon-Seung;Park, Inshik
    • Journal of Life Science
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    • v.22 no.11
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    • pp.1451-1455
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    • 2012
  • The study was conducted to investigate the effect of Maillard reaction products (MRPs) on enzymatic browning of crown daisy (Chrysanthmum coronarium var. spatiosum). The MRPs prepared by heating various amino acid and sugar at $90^{\circ}C$ caused a strong inhibitory effect on crown daisy polyphenol oxidase (PPO, ${\sigma}$-diphenol oxygen oxidoreductase, EC 1.10.3.1). As the reaction time of the solution containing glycine and glucose increased at $90^{\circ}C$, the production of MRPs was increased, whereas the amounts of glycine and glucose were decreased. Accordingly, the inhibitory effect of crown daisy PPO activity by MRPs was increased as the amounts of synthesized MRPs were increased. The MRPs synthesized from the various amino acids and sugars significantly reduced the PPO activity, particularly MRPs prepared by glutamine and xylose. The Michealis-Menten constant value ($K_m$) of crown daisy PPO with catechol as a substrate was 22.0 mM, and MRPs were a noncompetitive inhibitor against crown daisy PPO.

Levels of Resistance and Fitness in Glufosinate-ammonium-Resistant Transgenic Rice Plants (Glufosinate-ammonium 저항성 형질전환벼의 저항성 수준과 적응성에 관한 연구)

  • Yun, Young Beom;Kuk, Yong In
    • Weed & Turfgrass Science
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    • v.1 no.4
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    • pp.50-56
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    • 2012
  • The objectives of this research were to quantify resistance levels of transgenic rice expressing the bar gene to glutamine synthetase (GS)-inhibiting, and methionine sulfoximine and photosynthesis-inhibiting herbicide, paraquat, and compare the ammonium accumulation, chilling injury, and yield between transgenic and non-transgenic rice. The transgenic rice lines were 45-96-fold more resistant to glufosinate-ammonium than non-transgenic rice. The transgenic rice lines were also 18-fold more resistant to methionine sulfoximine, but was not resistant to paraquat, which has different target site. Glufosinate-ammonium increased the ammonium accumulation in leaves of non-transgenic rice plants, but had minimal or no effect on leaves of transgenic lines. The transgenic lines except for 258, 411, 607 and 608 were more susceptible during chilling and recovery than non-transgenic rice plants. The yield of transgenic lines 142, 144, 258 and 608 was similar or higher than that of non-transgenic rice in pot conditions.