• 기계와재료
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• v.23 no.1
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• pp.14-22
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• 2011

노화가 시작되면 체력이 저하되어 면역기능이 떨어져 쉽게 병에 걸리고 환경에 대한 적응력이 떨어진다. 특히 60세 이상이 되면 근육 양과 근력이 급격히 가속화되어 신체적으로 약화되기 시작한다. 노화는 자연스럽게 진행되지만 꾸준한 운동을 통해 근력 저하 속도를 늦출 수 있다. 근력 증강을 위한 다양한 기기 개발에도 불구하고 노인들이 사용하는데 어려움이 있다. 특히 노인 신체적 특성에 맞는 운동기기 개발이 절실하며, 노인의 흥미를 유발시켜 자발적 참여를 유도하는 환경이 제공되어야 한다. 가상현실 기술은 실재하지 않거나 먼 거리에 있는 환경을 가상세계로 생성시켜서, 인간의 오감을 각종 인터페이스 장치를 통해 신호를 전달하여 가상의 현실 환경에 실재하고 있다고 느끼도록 만들어 주고, 가상세계와 상호작용을 통해 의료 진단, 치료, 재활 등에 유용한 도구 및 환경을 제공한다. 이러한 가상현실 기술의 특성 때문에 노인의 운동 참여와 운동 효과를 극대화 할 수 있다. 본 논문에서는 근력의 특성을 분석하고 노화와 근력과의 관계를 조사하고, 상지근력 증강 운동기와 해당 가상현실 컨텐츠 그리고 관련 컨텐츠 개발 동향에 대해 제시하고자 한다.

• Physical Therapy Korea
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• v.3 no.2
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• pp.84-94
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• 1996

This paper reviews physiological changes in the nervous system of patients with hemiparesis that may contribute to muscle weakness. The discussion includes the important role that alterations in the physiology of motor units, notably changes in firing rates and muscle fiber atrophy, play in the manifestation of muscle weakeness. This role is compared with the lesser role that spasticity of the antagonist muscle group appears to play in determining the weakness of agonist muscles. The contribution of other factors that result in mechanical restraint of the agonist by the antagonist is discussed relative to muscle weakness in patients with hemiparesis. More studies on patients with hemiparesis are required to assess what role muscle strength training should play in rehabiliting patients after a stroke.

• Journal of Life Science
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• v.32 no.6
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• pp.482-490
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• 2022

Sarcopenia, a geriatric and multifactorial syndrome characterized by progressive systemic skeletal muscle disorder, may be associated with many comorbidities. Sarcopenia caused by a decrease in muscle mass and muscle strength is accompanied by the aggravation of various pathological conditions, and as life expectancy increases, its prevalence will continue to increase in the future. During the aging process, chronic oxidative stress and increased inflammatory responses act as major contributors to skeletal muscle loss. In addition, disruption of autophagy and apoptosis signals associated with dysfunction of mitochondria, which are essential for energy metabolism, accelerates the loss of muscle proteins. The pharmacological effect of cordycepin, a major physiologically active substance in the genus Cordyceps, which has been widely used for the prevention and treatment of various diseases for a long time, is directly related to its antioxidant and anti-inflammatory actions. In this review, we present the correlation between apoptosis, autophagy, protein catabolism, and satellite cell activity important for muscle regeneration using cordycepin for the prevention and treatment of sarcopenia. Although there have been few studies so far on the use of cordycepin for sarcopenia, previous studies suggest that cordycepin may contribute to inhibiting the age-related weakening of mitochondrial function and blocking the breakdown of muscle proteins. In addition, the protective effect of cordycepin on muscle cell damage is considered to be closely related to its antioxidant and anti-inflammatory activities. Therefore, it is considered that more continuous basic research is needed, focusing on the molecular biological mechanism of cordycepin, which is involved in the anti-aging of muscle cells.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.15 no.2
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• pp.93-97
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• 2015

Short-chain acyl-CoA dehydrogenase (SCAD) deficiency is an autosomal recessive hereditary metabolic disorder of mitochondrial fatty acid beta-oxidation. Mutations in the ACADS gene cause short-chain acyl-CoA dehydrogenase deficiency, which is characterized by developmental delay, hypotonia, seizure, and hypoglycemia. Here, we describe one Korean pediatric case of SCAD deficiency, which was diagnosed during newborn screening by tandem mass spectrometry and confirmed by molecular analysis. The level of C4 was typically elevated 5.23 mg/dL (reference range <1.5 mg/dL). This patient had a homozygous mutation [c.1031A>G, p. E344G] in ACADS. Therefore, we present a case of SCAD deficiency in an otherwise healthy neonate and her subsequent development and growth over four years.

• Journal of Korean Orthopaedic Sports Medicine
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• v.5 no.2
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• pp.100-104
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• 2006

The Incidence of groin injury was about 10% in football player These injuries occur most commonly in athletes participating in sports Involving cutting, quick accelerations and decelerations and sudden directional changes. Symptoms may range from intermittent episodes of mild discomfort to severe and chronic career-ending pain. Groin injuries may result from a variety of causes. We must keep in mind that many other conditions may also affect the groin. Because of the anatomy of the region is so complex. Ligament/muscle strains, nerve entrapment syndromes, sportsman's hernia, symphysitis, stress fractures and various hip pathologies are reviewed as causes of groin pain are reviewed as common causes of groin pain.

• Journal of Animal Science and Technology
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• v.46 no.3
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• pp.427-436
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• 2004

The current study was conducted to determine the effect of suspension method on satisfaction level of Korean consumers and objective meat quality traits in Hanwoo longissimus dorsi(LD), triceps brachii(TB) and semimembranosus(SM) muscles. Eighteen Hanwoo steers were slaughtered and alternative sides were hung either by pelvic bone(TS) or Achilles tendon(Al). Sensory characteristics, WB-shear force, sarcomere length, water-holding capacity, saroomere length and cooking loss were determined after a 7-d chiller ageing. Higher carcass quality grade received significantly(p < 0.05) greater eating quality for LD, but the grade did not affect eating quality for both TB and SM. TS did not influence objective and subjective meat quality for TB, but that significantly(P < 0.05) improved eating quality for LD and SM. The most noticeable result was that when SM was tenderstretehed, eating quality was equivalent to that of nonna1ly hung LD. In relationship between objective and subjective meat quality assessments, eating qualty for LD had a significant(P < 0.05) relationship with intramuscular fat content, while that for SM was greatly(P < 0.05) related to saroomere length. The current study indicated that pelvic hanging was an effective way to improve eating quality both LD and SM, and carcass quality grades did not greatly reflect eating quality of SM and TB. The data also implied that instnunental measurements poorly estimated the satisfaction level of Korean conswners.

• Physical Therapy Korea
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• v.8 no.4
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• pp.71-80
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• 2001

근위축성 측색 경화증 (amyotrophic lateral sclerosis: ALS) 환자에게 있어 호흡기능장애는 죽음에 이르게 하는 주요 원인 중 하나이다. 본 연구는 근위축성 측색 경화증이 있으며 호흡기능이 약화되어 있는 51세의 여성 환자를 대상으로 호흡운동 치료를 시행한 후 폐기능(pulmonary function)이 증진되었는지를 알아보고자 실시하였다. 연구 대상자는 6주간의 호흡운동 치료 프로그램에 참여하였다. 호흡운동 치료 프로그램은 횡경막 호흡(diaphragmatic breathing), 복부근육강화(abdominal mu scles strengthening), 지갑입술 호흡(pursed lip breathing), 그리고 동기 유발성 흡기폐활량계(incentive spirometer)를 이용한 흡기운동 등으로 구성되었다. 폐기능 검사는 이동식 호흡측정기(spirometer: MICROSPIROHI-198)를 이용해서 시행하였다. 또한 하지 에르고미터(cycle- ergometer)를 이용해 운동 시간을 측정함으로써 폐기능의 증진 여부를 알아보았다. 연구 대상자는 6주간의 호흡운동 치료 기간 동안 노력성 폐활량(forced vital capacity: FVC)과 정상 예측치에 대한 노력성 폐활량의 비율(percentage of the predicted forced vital capacity: %FVC), 그리고 하지 에르고미터의 운동 시간에 있어 현저한 증가를 보였다. 그러나 노력성 폐활량에 대한 1초간 노력성 폐활량 비(FEV1/ FVC)에 있어서는 약간의 감소를 보였다. 근위축성 측색 경화증 환자에게 6주간의 호흡운동 치료를 실시한 결과, 폐기능의 증진에 효과적임을 알 수 있었으며, 앞으로 더 많은 연구 대상자에게 그 효과를 알아보는 연구가 필요할 것이다.

• Physical Therapy Korea
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• v.9 no.3
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• pp.125-135
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• 2002

In most of the medical literature that discusses the common problem of movement in patients with cerebral lesions. This critical problem is ascribed to a mechanism involving uninhibited neural activity. The goals of neurological physical therapy are focus on reduce of muscle hypertonicity, facilitates muscle activities, and improve of performance in living environment. A variety of studies suggest that spasticity is a distinct problem and separate from the muscle weakness. It has become increasingly recognized that the major functional deficits following brain damage are largely due to negative features such as muscle weakness and loss of performance rather than spasticity. Adequate recruitment of prime mover, not release was able to carry out the movement tasks well. The strengthening exercise of spastic limbs on changes in muscle properties and performance skill, the repeated motor practice has been identified as crucial for motor recovery. This article support the concept that strengthening is an appropriate intervention to improve the quality of physical function in patients with central nervous system lesions. Further studies and therapeutic approaches should be efforts at improving motor neuron recruitment in agonist rather than reducing activity in antagonists while retraining muscle strengthening.

• Journal of Pharmacopuncture
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• v.6 no.1
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• pp.13-13
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• 2003

1. 도입 및 배경 Lou Gehrig 병이라고 알려져 있는 근위축성 측삭경화증은 중추신경계 중 운동신경의 퇴행성 변화에 의한 진행성 질환이다. 이 병은 근육의 마비와 약화, 강직의 진행과 더불어 언어장애, 연화장애, 호흡장애가 동반된다. ALS는 환자나 가족들에게 엄청난 고통을 주는 질환으로 이병은 발병 후 3-5년 내에 약 $75\%$가 사망한다. 그리고 연하장애가 주된 증상이거나 고령에서 발병하였을 때에는 생존기간이 더욱 단축되는 경향을 나타낸다. 그리고 치명적인 호흡장애로 인해 대부분 사망하게 된다. 현재 의학계에서는 이 병의 원인도 알고 있지 못하고, 증상에 대한 아무런 치료방법도 제시하지 못하고 있는 실정이다. 2. 역학 원발성 운동신경원성 질환의 발생률은 100,000당 약 7명이고, ALS는 이 중 약 $65-85\%$를 차지한다. 전 세계적으로 1년에 약 2-4명/100,000이 발생하고 있으며 시간이 경과할수록 점차 증가하고 있는 추세이다. 3. 연구방법 EMG나 Biopsy 등을 통해 신경과 전문의가 ALS로 진단한 환자 중 상지대학교 부속한방병원에서 3개월 이상 입원치료를 받은 환자 18명을 대상으로 임상연구를 진행하였고, 설문조사는 외래에 내원한 환자 중 설문에 응답한 환자 28명을 포함한 총 46명의 환자들을 대상으로 시행하였다. 치료방법은 침, 약침, 봉약침, 한약 등을 환자의 체질을 고려하여 변증에 따라 적용하였고, 환자의 상태 변화는 ALSFRS(ALS Functional Rate Scale)를 사용하여 관찰하였다. 4. 결과 본 연구결과 ALS의 치료에 한의학적 치료방법은 유효한 것으로 나타났다. 특히 본 질환이 시간이 경과하면서 $100\%$ 악화되는 질환임을 감안한다면 한의학적 치료를 통해 약 $40\%$의 환자에서 몸의 상태나 언어장애, 만성적 피로 등이 호전되었고, 근력도 증가되는 결과를 나타내었다.

• Journal of Digital Convergence
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• v.11 no.11
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• pp.613-620
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• 2013

This study was conducted to measure and analyze the changes in paraspinal muscles of acute and chronic low back pain patients using MRI, and to provide clinical basic data for diagnosis and treatment for low back pain. For this purpose, 20 patients with acute low back pain frome August 2012 to January 2013 which occurred within 12 weeks, and 20 patients with chronic low back pain that progressed over 12 weeks, were chosen as subjects, and their MRI measurements were compared with one another. As a result, in relation to in the fatty degeneration ratio of the left spine and right spine, there were significant differences in erector spinae and multifidus(p<.001), and in relation to the Fat Infiltration ratio between all the groups, there were significant differences in psoas major, erector spinae and multifidus between the acute low back pain patient group and the chronic low back pain patient group(p<.001). In the post-hoc test, multifidus and erector spinae in the acute low back pain group and chronic low back pain group showed the highest Fat Infiltration ratio. The serious Fat Infiltration of multifidus and erector spinae in the chronic low back pain group led to weakened strength of muscles that stabilize the spine. In conclusion, it is considered that this study would present important data and basis in making acute and chronic low back pain patients pay more attention to multifidus and psoas major during rehabilitation exercise, and selecting a rehabilitation exercise program.