• 한국응용과학기술학회지
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• 제38권3호
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• pp.750-761
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• 2021

이 연구는 노화된 흰쥐를 대상으로 규칙적인 저항성 운동에 유산소 운동을 병행하는 훈련을 실시하여 골격근에서 나타나는 혈관신생 관련 단백질 발현의 반응을 관찰하기 위해 수행되었다. 연구의 목적을 위해 자연적으로 노화된 SD계열 흰쥐(20-24개월령, N=18)를 사용하여 통제(CON, n=6), 저항성 운동(RE, n=6), 저항성+유산소 운동(RE+AE, n=6) 집단으로 구분하였다. 저항성 운동 집단은 실험동물용 사다리를 이용하여 매회 3세트×4회의 운동을 실시하였고 저항성 운동+유산소 운동 집단은 매회 2세트×3회의 사다리 오르기와 추가적인 30분간의 트레드밀 달리기를 수행하였다. 총 8주간의 운동 훈련 종료 후 가자미 근과 장지신근을 적출하여 분석에 사용하였다. 골격근에서 혈관신생 관련 단백질들(HIF-1α, VEGF, FLK-1, Ang-1, Ang-2)의 발현 수준을 분석하기 위해 western blot을 실시하였다. 연구결과, 저항성+유산소 운동 집단에서 가자미근(type I 근육)의 HIF-1α, VEGF, FLK-1, Ang-1, Ang-2 단백질 발현이 통제집단에 비해 높았으며 저항성 운동만 수행할 경우 HIF-1α, VEGF, Ang-1, Ang-2 단백질 발현이 통제집단에 비해 높았다. 또한 가자미근에서 저항성+유산소 운동훈련 집단의 Ang-2 to Ang-1 ratio가 저항성 운동 집단에 비해 높아 운동훈련 유형별 차이를 보였다. 한편, 장지신근(type II 근육)에서 HIF-1α는 저항성 운동 훈련에 의해서만 증가된 반면 VEGF와 FLK-1 단백질 발현은 두 훈련 유형 모두에서 증가되었고 운동 훈련 유형별 차이는 관찰되지 않았다. 또한 장지신근의 angiopoieitin 단백질들의 발현은 운동 훈련에 의한 차이가 없었다. 그러므로 노화에서 규칙적인 운동 훈련은 운동 유형에 관계없이 골격근 혈관신생 반응을 유도하며, 특히 저항성 운동에 유산소 운동의 병행은 type I 근조직 유형에서 혈관신생에 대한 추가적인 긍정적 효과를 가질 수 있다.

• 대한기계학회논문집B
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• 제37권12호
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• pp.1121-1127
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• 2013

본 논문은 인체 견관절의 재활훈련을 위하여 견관절 근육에서 근전도를 측정하고 기능적 전기자극을 인가하는 실험적 연구를 다룬다. 견관절 근골격계의 구성 및 운동형상과 주요 기능을 토대로, 시상면 운동에서 주요 역할을 하는 견관절 근육을 실험대상으로 선정하였다. 첫 번째 실험으로 관절 각도에 따른 주요 근육의 표면근전도를 측정하였다. 관절 각도 변화와 표면면근전도 변화가 선형 비례하는 경향이 나타났다. 두 번째 실험으로 견관절 근육에 기능적 전기자극을 인가하면서 관절 각도를 측정하였다. 전기자극의 일정 범위에서 자극 전류 증가에 따라 관절 각도가 증가하는 경향이 나타났다. 능동형 재활훈련의 방안으로, 근전도 측정에 의해 근육의 운동의지를 감지하고 기능적 전기자극으로 근육의 장력 발생을 보조하는 게 가능함을 확인하였다.

• 척추신경추나의학회지
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• 제15권2호
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• pp.19-31
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• 2020

Objectives This study was conducted to survey the trends of Korean medicine clinical research using radiological measurements of the musculoskeletal system. Methods We searched four domestic research databases (OASIS, NDSL, RISS, KISS) and three academic journals (Journal of Korean Medicine Rehabilitation, The Journal of Korea CHUNA Manual Medicine for Spine & Nerves, and Journal of Acupuncture Research). Selected studies were classified by publishing year, journal, the purpose of studies, and body region mainly researched in studies. Additionally, we analyzed the radiological measurements used in each body region. Results A total of 80 studies were selected. Most of the studies were published since2000. Most studies were published in the Journal of Korean Medicine Rehabilitation. The mainly researched body region was the lumbar spine. The main purpose of the studies was to analyze the characteristics of the disease. Conclusions Further research is needed about other different fields of Korean Medicine using X-ray on various body region and studies with purpose of analyzing radiological measurements need to be researched more.

• 운동과학
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• 제26권2호
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• pp.103-114
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• 2017

INTRODUCTION: Regulation of skeletal muscle protein mass is implicated not only in exercise performance but in metabolic health. Exercise in combination with nutrition, particularly dietary protein/amino acid intake, are the pragmatic approach that effectively induces muscle anabolic response (i.e., muscle hypertrophy) through regulating protein synthesis and breakdown. PURPOSE: The purpose of this review was to summarize available data on the effect of exercise intervention and amino acids intake on muscle protein synthesis and breakdown and provide an insight into development of an effective exercise intervention and amino acids supplements, applicable to training practice. METHODS: In this review, we have reviewed currently available data mainly from stable isotope tracer studies with respect to the effect of exercise intervention and protein or amino acid supplement on muscle protein anabolic response. CONCLUSIONS: Taken together, exercise alone may not be effective in achieving a positive net muscle protein balance due to the fact that protein breakdown still exceeds protein synthesis until nutrition intake such as protein/amino acids. It appears that muscle anabolic response increases in proportional to the amount of protein intake up to 20 - 35 g depending on quality of protein, age, differences on exercise intensity, duration, and frequency, and individual's training status

• 기계와재료
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• 제23권1호
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• pp.24-32
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• 2011

최근 다양한 연구를 통하여 전신 진동기 운동이 신체의 근골격계, 순환계 및 내분비계 등에 효과적임이 보고되고 있다. 특히 전신 진동운동이 노인의 낙상예방, 파킨슨 및 뇌졸중 환자와 같은 신경학적 질환자의 자세조절 및 기능향상을 위한 재활치료 방법으로 효과가 있다고 밝혀졌다. 그러나 아직까지 전신 진동운동에 적합한 의료 허가를 받은 제품이 없으며, 일부 유사한 진동감을 제공하는 기기를 위주로 제작되고 있는 상황이다. 추후 의료기기의 수요를 고려할 때 고령사회로의 진입 속도가 빨라짐에 따라 노인들에게 적합한 진동기의 개발이 필요하다. 노인들은 운동참여에 보수적이며 사회성이 떨어지기 때문에 운동기의 기능적 요건과 더불어 참여를 유도하는 환경 요인을 함께 제공할 필요가 있다. 본 논문에서는 진동 운동기를 이용한 운동 효과를 분석하고 전신 진동운동에 적합한 가상현실 컨텐츠를 제시하였으며, 국내외 개발 및 연구 중인 기기와 컨텐츠 개발 동향을 제시하였다.

• Clinical Pain
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• 제20권1호
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• pp.7-14
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• 2021

Musculoskeletal ultrasound has evolved as the essential tool to diagnose and guide intervention procedures in people with neuromusculoskeletal conditions. Image optimization and understanding device operations are core components for ultrasound guided intervention procedure training. All ultrasound machines share the common operative features and there are various buttons for the features in the device control panel. Ultrasound "knobology" refers to the thorough understanding of imaging optimization. This review addressed basic information for the transducers, depth setting, gain and focus control, different modes focusing on brightness and doppler modes.

• 한방재활의학과학회지
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• 제34권1호
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• pp.65-81
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• 2024

Objectives This study aimed to understand the general research trends, applicated disease, and methodology of transcutaneous/percutaneous vagus nerve stimulation, contemplating its clinical use in traditional Korean medicine and future research directions. Methods A scoping review was conducted following Arksey and O'Malley Framework Stage and adhering to the PRISMA extension for scoping reviews: checklist and explanation. Papers published until October 30, 2023, were investigated across 10 databases (PubMed, Embase, Scopus, Web of Science, China National Knowledge Infrastructure, Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, KMbase, Science ON, Research Information Sharing Service. The search terms used were 'Transcutaneous/Percutaneous vagus nerve stimulation'. Results Since 2021, the application of transcutaneous/percutaneous vagus nerve stimulation for musculoskeletal symptoms has been actively researched, predominantly in Asia (37%), Europe (37%), and North America (21%). All 19 papers were part of clinical studies. Chronic pain was noted that most applied disease, it also was found to potentially aid in acute post-surgical pain relief. Major assessment tools include not only simple pain metrics but also pain perception, vagal nerve tension, quality of life, and inflammatory markers. Most procedures were carried out through the ear, which offers a favorable site for therapeutic stimulation without notable side effects. And parameter analysis, frequencies typically ranged around 25 Hz to 30 Hz, while pulse widths were commonly set at 250 ㎲ or 300 ㎲. Conclusions Transcutaneous/percutaneous vagus nerve stimulation is easily accessible through acupuncture in Korean medicine. Therefore, if future studies establish parameters and clinical significance, it could be utilized as a therapeutic modality.

• 한방비만학회지
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• 제22권1호
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• pp.86-92
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• 2022

26명의 환자에게 8~12주동안 산삼복합약침과 한약을 병행한 식이요법을 시행하여 체성분 변화에 미치는 영향을 알아보았다. 체성분 검사 결과 체중, BMI, 골격근량, 체지방량, 복부지방률, 내장지방단면적, 체지방률이 유의하게 감소하였고, 체중이 감소하면서 골격근량이 감소하긴 하였으나 체지방량 위주의 감소로 골격근의 비율은 오히려 유의하게 증가하였다. 태음조위탕을 증례에 맞게 가감하고, 하루 한 시간 혹은 만 보 걷기의 운동지도를 통해 하루 400~800 kal의 초저열량 식이로 인해 야기될 수 있는 부작용 중 일시적인 현기증과 무기력감 외에 탈모, 부종, 설사, 월경 이상 등은 관찰되지 않았다. 향후 체성분 변화뿐만 아니라 생화학적 검사나 골밀도 검사를 통한 장기적인 탐색이 필요할 것으로 생각한다.

• 한방재활의학과학회지
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• 제30권3호
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• pp.151-162
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• 2020

Objectives This study aimed to evaluate the effectiveness of postoperative Korean rehabilitation treatment for patients with musculoskeletal disorders. Methods The medical records of patients undergoing Korean medical rehabilitation after a musculoskeletal surgery, from January 1, 2016, to December 31, 2019, were analyzed retrospectively. The effect of treatment was evaluated by using a numeric rating scale (NRS) and questionnaire for each surgical site. When the same patient was re-admitted after discharge, it was treated as the same case if it was within 7 days from the discharge date; otherwise, it was treated separately. If the period of hospitalization was within 7 days or the chief complaint was not related to musculoskeletal surgeries, the case was excluded. Results In total, 480 cases were included in this study. Acupuncture (99.8%), moxibustion (95.6%), cupping (97.5%), Chuna manual therapy (81.5%), Korean medical physiotherapy (61.0%), Daoyin exercise therapy (26.3%), and herbal medicine (87.7%) were used as the Korean medical rehabilitation treatments. A significant improvement was noted when comparing the NRS and questionnaire results for each surgical site at the time of admission and discharge. Conclusions Korean medical rehabilitation can be effectively used for patients who have undergone musculoskeletal surgeries, to relieve pain and enable returning to daily activities. However, further research with a high level of evidence is necessary to support this finding.

• Clinical Pain
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• 제18권2호
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• pp.82-87
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• 2019

Objective: To evaluate which Korean pain descriptors are frequently used in the patients with neuromusculoskeletal diseases and compare the frequency of Korean pain descriptor according to age, gender, pain pattern and intensity, and clinical diagnosis. Method: Two hundreds sixty nine patients with neuromusculoskeletal diseases were enrolled in this study. The patients were asked to fill out a pain questionnaire using Korean. The Korean pain descriptors were collected and classified according to neurophysiological mechanism. The frequency of Korean pain descriptor was analyzed by age, gender, pain pattern and intensity, and clinical diagnosis. They were divided into axial spine and peripheral joint pain group depending on the location of causal disease and shoulder pain descriptors were divided into intra-articular and bursa group. Results: Among 24 Korean pain descriptors, 'arida' was the most common pain descriptor, followed by 'ssusida' and 'jjireunda'. When the pain descriptors were classified according to neurophysiological mechanism, superficial somatic pain was the most common, followed by deep somatic pain. There was a significant difference in the frequency of the pain descriptor between axial spine and peripheral joint pain group (p=0.007). The pain descriptor 'danggida' was used significantly more in the patients with axial spine pain than peripheral joint pain (p=0.024). However, there was no significant difference in other factors. Conclusion: The patients with neuromusculoskeletal diseases expressed their pain using various Korean pain descriptors with stabbing nature and superficial somatic pain. Our results may be helpful to assess and develop a new Korean pain quality measure in the patients with neuromusculoskeletal diseases.