• Annual Conference of KIPS
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• 2024.05a
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• pp.702-704
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• 2024

최근 사회적으로 근감소증에 대한 관심이 높아지면서 노인성 근감소증 시장이 골다공증 시장을 뛰어 넘을 것으로 전망하고 있다. 진단 방법으로 의료영상기반으로 근육량을 인공지능 기술로 측정하여 근감소증 진단에 적용하는 연구가 활발하게 진행되고 있다. 본 논문에서는 복부 CT 영상에서 L3 부위의 근육량을 기반으로 한 진단 기준을 이용하여 아시아 피험자의 T-score를 기반으로 근감소증 진단을 자동화하였다. 특히 복부 CT영상의 업로드와 함께 자동으로 근육량을 측정하여 개인별 상태를 확인할 수 있도록하여 근감소증 진단을 지원 할 수 있도록 개발하였다. 그리고 이를 기반으로 4가지 간 질환 환자의 L3 부위 근육량을 측정하여 근감소증과의 상관성을 확인하였다. 이는 다양한 기저 질환과 근감소증과의 연관성 연구에 도움이 될 것으로 기대한다.

• 한국노년학
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• v.36 no.3
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• pp.727-749
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• 2016

This systematic review was performed to investigate relationship between sarcopenia and cognitive function among community-dwelling older adults. Studies which reported prevalence rates of sarcopenia in community-dwelling older adults, relationships between sarcopenia and cognitive dysfunction, or effective interventions in alleviated symptoms of sarcopenia were selected. Of 43 studies reviewed, prevalence rate of sarcopenia ranged from 2.5-42.4% in 25 studies, and 4 studies revealed a significantly positive correlation between sarcopenia and cognitive dysfunction. Among 12 randomized-control trials (RCTs), exercise intervention was used in 2 studies; nutrition intervention in 6; and 4 studies included both the exercise and nutrition interventions. All interventional studies reported positive effects on muscle mass, muscle strength, or physical function. However, only 6 studies met the high quality criteria of Risk of Bias, and there was no study which evaluated cognitive function as an outcome measure. Therefore, this study draws attention to the lack of high-quality RCTs and exclusion of cognitive function as an outcome measure in the research of sarcopenia. A comprehensive and sustained system including standardized sarcopenia screening, assessments of cognitive functioning, and evidence-based intervention programs is needed in order to prevent and manage sarcopenia amongst older adults in the community.

• Journal of agricultural medicine and community health
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• v.46 no.1
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• pp.23-31
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• 2021

Objectives: Frailty and sarcopenia are recent important concepts in elder health care. Sarcopenia is the most important factor influencing frailty, and exercise and nutritional status are known to affect sarcopenia. The purpose of this study was to identify the relationship between nutritional status, sarcopenia, and frailty. Methods: This study was a cross-sectional design. The subjects of this study were 411 elderly people aged 65 or older from 10 villages in Gyeongnam. The survey tools were the K-FRAIL for frailty, the GDS-SF for depression, the SARC-F questionnaire for sarcopenia, and the DETERMINE for nutritional status. Frequency analysis, the chi-square test, and multiple logistic regression analysis were performed using the SPSS 25.0 program. Results: As a result of the chi-square test, there was a significant difference in the nutritional status and the frailty proportion (p<0.001), and there was a significant difference between frailty and suspected sarcopenia (p<0.001). After adjustment, nutritional status was significantly associated with sarcopenia (OR=2.946, p<0.001). In addition, nutritional status was significantly associated with frailty (OR=2.958, p<0.001), and sarcopenia also had a significant effect on frailty (OR=5.898, p<0.001). Finally, even after including sarcopenia, nutritional status had a significant effect on frailty (OR=2.246, p=0.002). Conclusions: Nutritional status can have both a direct effect on frailty and an indirect effect through sarcopenia, and it was found that sarcopenia also affects frailty. Therefore, it is necessary to evaluate sarcopenia and nutritional status and to evaluate their levels in the elderly and to take appropriate interventions.

• The Journal of the Convergence on Culture Technology
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• v.9 no.3
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• pp.737-744
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• 2023

Sarcopenia is an increasingly common disease among the elder that has recently received attention. Although the causes of sarcopenia are diverse, aging, dietary habits, lack of exercise are the one of the major factors. As the causes of sarcopenia are diverse, it is important to develop strategies for prevention and treatment. However, predicting sarcopnia accuartely is difficult due to the variety of factors involved. Here, machine learning can significantly improve the accuracy and convenience of predicting sarcopenia. However, since lifestyle habits and biological data are vast, using data without preprocessing may be inappropriate in terms of time complexity and accuracy. This paper reviews recent literature on sarcopnia and its causes, focusing on preprocessing the data to be used in sarcopnia prediction machine learning accrodingly.

• Journal of Oral Medicine and Pain
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• v.26 no.1
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• pp.51-58
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• 2001

다양한 자세에서 교합장치의 두께가 저작근에 미치는 영향을 근전도학적으로 평가하고자, 측두하악장애의 징후와 증상이 없고 정상교합을 가진 성인 8명을 대상으로, 교합장치를 장착하지 않은 상태에서와 4.3, 6.0, 8.1mm 두께를 가진 교합장치를 장착한 상태에서 직립위, 식사위 그리고 앙와위에서 최대 이악물기 상태의 좌, 우측 교근 몇 전측두근의 근활성도를 채득, 분석하여 다음과 같은 결과를 얻었다. 1. 전측두근에서는 교합장치를 장착하지 않은 상태보다 교합장치를 장착한 상태에서 근활성이 유의하게 감소하였고 (p<0.05), 교근에서는 차이가 없었다. 2. 직립위에서 전측두근의 근활성은 교합장치를 장착하지 않은 상태보다 8.1mm 두께의 교합장치를 장착한 상태에서 유의하게 감소하였다 (p<0.05). 3. 식사위에서 전측두근의 근활성은 교합장치를 장착하지 않은 상태보다 8.1mm 두께의 교합장치를 장착한 상태에서 유의하게 감소하였다 (p<0.05). 4. 앙와위에서 전측두근의 근활성은 교합장치를 장착하지 않은 상태보다 4.3, 6.0, 8.1mm 두께의 교합장치를 장착한 상태에서 유의하게 감소하였다 (p<0.05).

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.07a
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• pp.305-307
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• 2023

본 연구는 전방머리자세 대학생을 대상으로 목뼈안정화운동이 머리뼈척추각, 깊은목굽힘근 지구력 및 뒤통수밑근 근긴장도의 변화를 알아보고자 하였다. 이 연구 결과 CSEG에서 CVA, DNFET에서 유의하게 증가하였으며 뒤통수근 근긴장도에서는 경직도에서만 유의하게 감소하였다. 목뼈 안정화운동은 목뼈의 중립자세를 유지하면서 깊은목 굽힘근 활성화되고 근지구력이 향상되었으며, 턱을 당기는 동작으로 튀통수근의 경직이 감소한 것으로 생각된다. 또한 지구력 증가시키고 근 긴장도에 감소는 통증을 조절함에 있어서도 도움이 될 것이다. 따라서 목뼈안정화운동은 깊은목굽힘근과 뒤통수근의 개선을 위한 중재방법임을 확인할 수 있었으며, 전방머리자세 예방하기 위해 필요할 것으로 생각된다.

• Annual Conference of KIPS
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• 2022.05a
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• pp.535-538
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• 2022

근감소증은 영양부족, 운동량 감소 그리고 노화 등으로 정상적인 근육의 양과 근력 및 근 기능이 감소하는 질환을 말한다. 근감소증은 보편적으로 유럽 근감소증 실무그룹분석(EWGSOP)에서 정의한 측정 방법을 따른다. 본 논문에서는 근감소증 진단을 위한 영상 분할 모델을 개발하고 외부검증하는 방법에 대해서 제안한다. 우리는 CT 영상에서 L3 영역을 선별하여 자동으로 근육, 피하지방, 내장지방을 분할할 수 있는 인공지능 모델을 U-Net을 사용하여 개발하였다. 또한 모델의 성능을 평가하기 위해서 분할영역의 IOU(Intersection over Union)를 계산하여 내부검증을 진행하였으며, 타 병원의 데이터를 이용하여 같은 방법으로 외부검증을 진행한 결과를 보인다. 검증 결과를 토대로 문제점과 해결방안에 대해서 고찰하고 보완하고자 했다.

• Journal of Life Science
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• v.33 no.7
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• pp.574-585
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• 2023

Sarcopenia is a leading cause of increased medical and nursing care costs among the elderly. In Korea, preventive measures for sarcopenia are mostly targeted toward the general elderly population without specific diseases. However, it is also necessary to implement measures for elderly individuals living in nursing homes and hospitals, where the prevalence of sarcopenia is high. Currently, computed tomography and/or magnetic resonance imaging are considered standard diagnostic tools. However, their complexity and time-consuming nature make them unsuitable for clinical use. The exact pathophysiological mechanisms of sarcopenia are unclear, as they involve various molecular biological pathways, including decreased exercise, protein and nutrient intake, changes in testosterone and growth hormone, and inflammation. Sarcopenia symptoms can lead to several diseases, such as osteoporosis, fractures, dementia, diabetes, and cardiovascular disease. Vitamin B deficiency is a significant factor in sarcopenia induction, with B vitamins being directly involved in energy and protein metabolism and nerve function. Vitamin B deficiency can lead to neuromuscular and neurogenic disorders, which often overlap with sarcopenia. Suboptimal intake of B vitamins, malabsorption, and anorexia are common among the elderly. This study aims to provide information on the role of water-soluble B vitamins in preventing and controlling muscle mass loss and deterioration among the elderly with sarcopenia. In addition, we discuss the potential of myokines from the B vitamin family in modulating sarcopenia.

• The Journal of the Korea Contents Association
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• v.18 no.10
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• pp.165-174
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• 2018

The purpose of this study was to examine the association metabolic syndrome with sarcopenia in Korean stroke patients. We used the Korean National Health and Nutrition Examination Survey data from 2008 to 2011 and enrolled a total of 316 stroke patients older than 40 years. Data were analyzed by Rao-Scott ${\chi}^2-test$, generalized linear model and composite sample multiple logistic regression. The prevalence of sarcopenia was 47.3% in men and 46.3% in women. The prevalence of metabolic syndrome was 50.3% in men and 73.6% in women. After adjusting for age, smoking status, alcohol consumption, exercise, education, income, sroke sequla and stroke duration, men with sarcopenia had increased risk of metabolic syndrome (95% CI: 2.454-18.482, p<.001). This finding can be used to develop evidence-based health promotion program to prevent stroke reccurance for stroke patients.

• 한국체육학회지인문사회과학편
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• v.58 no.4
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• pp.423-433
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• 2019

The purpose of this review is to summarize current knowledge regarding animal sarcopenia and frailty models and their diagnosis indexes. In addition, we introduce the effects of exercise interventions on sarcopenia and frailty syndrome. Data collection and analysis (fifteen published articles from 2005~2017) were conducted by using keywords' sarcopenia index, frailty index, exercise and mice, and so on' in academic search engines such as Google scholar and Pubmed. Sarcopenia and frailty are the representative syndromes in elderly peoples which those symptoms can be effectively prevented or delayed by extremely adjusted long term exercise interventions (The combined oxidative and resistant exercise program might be ideal.).