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Black Hair Follicular Dysplasia in a Shih Tzu (Shih Tzu 견에서 발생한 Black Hair follicular Dysplasia 일례)

  • Kim Sung-ryong;Kim Young-in;Seo Jeong-a;Park Ji-won;Jeong A-young;Lee Keun-woo;Oh Tae-ho
    • Journal of Veterinary Clinics
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    • v.22 no.2
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    • pp.157-159
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    • 2005
  • Two-month old male Shih Tzu weighing 2.1 kg was presented with alopecia in black-haired areas of the skin. The hair loss had been present since five weeks of age. There was no history of pruritus on any part of the body. No other symptoms had been recognized. Physical examination found no abnormalities other than hair loss. Skin examination showed marked alopecia of black-haired area of the body. The white areas appeared to have hair growth of normal density and texture. Affected pigmented areas showed no evidence of skin lesions. Skin scraping and fungal culture were negative. Microscopic examination of plucked black hairs showed marked pigment clumping in the remnants of the follicles and were mainly in telogen phase. But white hairs were normal in various stages of hair growth. The diagnosis of black hair follicular dysplasia was made based on the history, alopecia of the pigmented areas, the confinement of abnormalities to dark areas, and the normal unpigmented areas.

The Effect of Circle Contact Lens on the Stability of Tear Film (써클콘택트렌즈가 눈물막 안정성에 미치는 영향)

  • Lee, Sehee;Hyung, Sung Min;Koh, Seung Hwan;Park, Mijung;Kim, So Ra
    • Journal of Korean Ophthalmic Optics Society
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    • v.20 no.2
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    • pp.125-131
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    • 2015
  • Purpose: The effect of pigmentation in circle contact lens on lens wearers' tear film stability was investigated in this study. Methods: Non-invasive tear film break-up times of 54 normal eyes before and after lens wearing in twenties and the portion of first tear breakup were measured. The frontal and back surface roughness of circle contact lens was further observed with a scanning electron microscope. The clear lens which was made of hilafilcon B and circle contact lenses which were made of hilafilcon B, polymacon and copolymer of HEMA NVP were tested. Results: Non-invasive tear film breakup time was significantly reduced compared with it before lens wearing. In some case, statistically significant difference in tear film breakup time was also observed between circle contact lenses. The tear file break-up was usually early started in lower than upper portion, and in temporal than nasal portion although there was variation in the lens material. The tear film break-up of circle contact lenses made of hilafilcon B was more commonly observed in peripheral portion(pigmented area) compared with clear contact lens made of same material. Conclusions: The present study revealed that the stability of tear film was affected by wearing circle contact lens and the result seems to be used as the basis for the problem solving that can occur due to the pigmentation when wearing circle contact lens.

Effect of Medicinal Herb Prepared through Traditional Antidiabetic Prescription on α-Glucosidase Activity and Evaluation Method for Anti-Melanogenesis Agents Using α-Glucosidase Activity (당뇨 처방에 근거한 생약재의 α-Glucosidase 활성 저해 효과 및 이를 활용한 미백 소재 평가법)

  • Kim, Mi Jin;Im, Kyung Ran;Yoon, Kyung-Sup
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.7
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    • pp.993-999
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    • 2015
  • For the purpose of investigating the in vitro antidiabetic activity of a medicinal herb and herb mixture extracts prepared through traditional antidiabetic prescription, this study examined ${\alpha}$-glucosidase inhibitory activity. Tyrosinase, a type I membrane glycoprotein, is synthesized and glycosylated in the endoplasmic reticulum (ER) and Golgi. The enzyme is subsequently transported to melanosomes, where it participates in melanogenesis. Previous studies showed that disruption of early ER N-glycan processing by an ${\alpha}$-glucosidase inhibitor suppresses tyrosinase enzymatic activity and melanogenesis. According to the results, most oriental medicinal herbal extracts were stronger than acarbose and N-butyldeoxynojirimycin, known as an ${\alpha}$-glucosidase inhibitor. Interestingly, ethyl acetate layer of enzyme hydrolyzed Cheongsimyeonjaeum had an inhibitory effect on melanin synthesis in B16F1 cells, although it did not inhibit tyrosinase activity directly. Together, ${\alpha}$-glucosidase inhibition activity could be used to evaluate anti-melanogenesis, although cross-checking with melanin inhibitory assay is recommended.

Children's Perception about Rest and Naps in Early Child Care and Education Centers Based on the View of Respecting Children's Rights (아동권리 존중 측면에서 본 휴식 및 낮잠에 대한 유아들의 인식)

  • Lee, Soon Hee;Suh, Young Sook
    • Korean Journal of Childcare and Education
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    • v.9 no.5
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    • pp.335-355
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    • 2013
  • The purpose of this study was to investigate children's recognition and needs about rest and naps at child care education centers, in the view of respecting children's rights. The participants were 40 children(20 4 year olds and 20 5 year olds), attending B Public Child Care Education Center in Seoul. The research methods were accomplished by participant observation in project activities and interviews with semi-structured questions. The collections of this process which were recorded document materials and video materials were analyzed by transcribed method. The results of this study were as follows: First, the meaning of the children's recognized rest showed time for family together, time for fun play, time required when they were very stressful and angry, and time for eating delicious meals. Second, children recognized that nap time in the child care center was time for a forced nap, time for listening to quiet music, and time for feeling good after a nap. Third, as for the needs to take a rest and a nap for children, they wanted to rest when they came together at full day class after their friends had returned home, they wanted a special area except the classroom, and they wanted to be cared for by familiar adults. Based on these results of the study, future research directions were proposed in terms of respecting children's rights of enjoying a rest and a nap.

Morphological Characteristics and Habitat Types of Rattus norvegicus and R. tanezumi Collected in Jeju Island (제주도에서 채집된 Rattus norvegicus와 R. tanezumi의 서식지 유형과 형태적 특성)

  • Kim, Tae-Wook;Joo, Sang-Min;Oh, Ah-Reum;Park, So-Jin;Han, Sang-Hyun;Oh, Hong-Shik
    • Korean Journal of Environment and Ecology
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    • v.27 no.5
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    • pp.550-560
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    • 2013
  • This study was investigated the morphological characters, secondary sexual dimorphism, and habitat patterns of Korean Rattus animals collected on Jeju Island from April 2005 to October 2012. Two wild rat species, namely R. norvegicus and R. tanezumi were identified on Jeju Island based on morphological characteristics and molecular data; however, R. rattus, which had recorded formerly, was not found in this study. Individuals of R. norvegicus were captured from urban, rural, and natural habitats, while those of R. tanezumi were specially found in animal farms and the surrounding areas. Comparing of morphological characters of two species, R. norvegicus had a shorter tail and ears than R. tanezumi (p<0.05), and the ratios of tail length and ear length to those of head-body length showed significantly differences between two species (p<0.05). The body weights (BW) of urban populations of R. norvegicus were significantly heavier than those of rural populations (p<0.05). No secondary sexual dimorphism was found in R. norvegicus, but females of R. tanezumi showed heavier BW than those of males (p<0.05). These findings suggest that it is necessary to revise the records for the existence of R. tanezumi and to confirm the animal fauna and elucidate the distribution and ecological characteristics from further studies using extensive sampling and detailed investigations on Jeju Island and also on the Korean Peninsula.

VLSI 설계와 CAD 기술개발 연구 전략 -다음 세대 컴퓨터 개발을 위한-

  • 이문기
    • The Magazine of the IEIE
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    • v.11 no.5
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    • pp.42-50
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    • 1984
  • 국내의 다음세대 컴퓨터 개발을 위한 VLSI 설계와 CAD 분야에 대한 연구 방향을 제시한다. 연구의 목표는 국제적으로 경쟁할 수 있는 VLSI 설계능력과 백만개 정도의 트랜지스터로 자성된 회로를 경제적으로 설계하기 위한 CAD 기술과 System의 확립이다. ·새로운 회로 구조와 알고리즘에 대한 연구 · CAD 도구와 언어의 개발에 관한 첨단 CAD 기술개발연구 · VLSI 설계에 필요한 CAD 도구 이용과 개발에 필요한 표준 인터페이스, 네트워킹, 컴퓨팅 하드웨어. 시스템 소프트웨어에 대한 연구등의 부분으로 크게 나눌 수 있다. 이용 가능한 CAD system을 평가하고 개선하며 첨단 CAD에 대한 소프트웨어와 하드웨어에 대해 · 컴퓨팅 하드웨어 · 프로그램 분위기 · 네트워킹 능력 ·자료 교환을 위한 표준인터페이스 등에 관해 조사분석도 병행한다. CAD에 관한 세부적인 연구 과제는 · 시스템 사양언어 · 설계 검증 ·시스템시뮬레이션· 설계 합성 · 설계 해석· 설계 방법론·디바이스와 공정 모델링 프로그램 등이다. 고속 계산용 VLSI에 관한 구조와 알고리즘은 행렬 계산을 위한 ·분산 배열 처리 회로 ·시스토릭 (Systolic) 배열 회로 ·셀률라(Cellular) 논리 회로 · 3차원 배열 회로 와 · 비규칙적 계산 알고리즘을 갖는 VLSI가 있다. VLSI설계훈련과 CAD 기술 축적을 위해 CAD enter를 설립하여 전국적인 CAD 네트워킹을 관계 연구소와 여러 대학에 가설하며, MPC 계획을 추진한다. VLSI설계 가능성이 입증되면 VLSI 설계능력을 더욱 향상 시키기 위해 0.5∼1.0mm기술의 silicon faundary를 설립한다. 연구 개발 조직은 대학, 산업체. 연구소가 삼위일체가 되어 수행될 수 있도록 연구 개발 위원회를 설치 운영하며 경쟁적이며 경제적으로 연구 업무를 집행하는 것이 바람직하다.았다.형질에 관여하는 귀전자에 미치는 기구에 대하여 검토할 여타가 있다고 보여진다. 분해능의 특징으로 미루어 앞으로는 레이저를 이용한 계측 방법이 그 주류를 이룰 것으로 사료된다. 우선 본 해설은 기체의 온도 및 농도의 광학적 측정방법중 Raman산란광 검출법에 대하여 실제로 측정하는 입장에서 간단히 소개한다.lity)이, 높은 $GA_3$함량에 기인된다'는 주장은 본실험(本實驗)으로 부인(否認)되었다. 따라서, 응용학적(應用學的) 측면에서 고려해 볼 때, 리베스식물(植物)의 육종기간 단축을 위한 모든 화아분화(花芽分化) 촉진 조치는 P.J.-식물(植物)이 20. node이상 생육하였을 때 취하는 것이 효율적인 것으로 결론 지어진다.앞당겨진 7月 셋째 週였다. 8. Culex (Culex) tritaeniorhynchus summoro년의 最大發生 peak는 1981年, 1982年 모두 8月 둘째 週였다. 9. Anopheles (Anopheles) sinensis의 最大發生 peak는 1981年에 7月 다섯째 週, 1982年은 2週 앞당겨진 7月 셋째 週였다. 10. 重要 3種의 最大 peak를 比城하면 Culex (Culex) pipiens pallens와 Anopheles (Anopheles) sinensis는 1981年과 1982年 모두 最大 peak時期가 同一하였으며, Culex (Culex) tritaeniorhynchus summoro년는 2年間 모두 8月둘째 週에 나타났다.osterior to manubrium and anterior to aortic arch) replacing the normal mediastinal fat. (2) In benign thymoma, the marging of the mass was smooth and the normal fat

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Simplification of Face Image using Cubic Spline Interpolation (Cubic Spline Interpolation을 이용한 얼굴 영상의 단순화)

  • Kim, Jung-Min;Jung, Eun-Kook;Kim, Sun-Shin
    • Journal of the Korean Institute of Intelligent Systems
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    • v.20 no.5
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    • pp.722-727
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    • 2010
  • This paper is presented to study simplification of face image using cubic spline interpolation for a business card with 2D barcode. People often forget business card's owner because business cards don't be included a face picture generally. To solve such problem, many applications have be developed through mobile devices, Internet and so on. But they couldn't caught up with value of existing business card mad by paper. Hence, some methods which can put information on business card using 1D or 2D barcode had suggested. but they couldn't include information like face image or company logo image which have too much data. Therefore, we study the simplification method of face image to encode from a face image to 2D barcode. The simplification method using spline curves defined by feature points which we dotted on face, ears, hair, eyebrows, nose, lips, neck, etc.. on a face area. for experiment, we see real face image and simplified face image made by proposed method after we automatically extract face watch through camera. In experimental results, data of simplified face image was reduced as small as it can be expressed by 2D barcode, and confirmed that it can effectively express features.

Studies on the Natural pH Adjusters for Kimchi (김치용 천연 pH 조정제 연구)

  • Jang, Kyung-Suk
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.18 no.3
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    • pp.321-327
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    • 1989
  • The buffer activities of 72 species of natural pH adjusters in Chinese herb medicine materials of food materials by 100% acetic acid$({\mu}{\ell})$ titration until pH 4.0 in the $100m{\ell}$ of 1 % solution of the pH adjuster were evaluated for their abilities to retard acidification of Kimchi. There were 14 species above 100 of buffer activity such as Glycerehizae Radix(150), Siler divaricatum Benthan et Hooker etc. among selected Chinese herb medicine materials. In selected Chinese herb medicine materials, the buffer activities of Erillae Herba+Glycyrehizae Radix, Erillae Herba+Dioscoreae Rhizoma, Erillae Herba+Glycyrehizae Radix, Erillae Herba+Dioscoreae Rhizoma, Erillae Herba+Puerariae Radix, Chrysanthenum sinense+Puerariae Radix, Alismatis Rhizoma+Angelicae gigantis and Dioscoreae Rhizoma+Puerariae Radix were above 150 by same amount blending each other. Species and buffer activities of natural pH adjusters, which are higher buffer capabilities in mushroom, bean and vegetable classes were mungbean(207). soybean(160), pease(190), fungus(225), Garland chrysanthemum(200), amaranth(175), wild sesame leaf(200), parsley(202) and green pepper(257) etc. Species and buffer activities of higher buffer capabilities of natural pH adjusters of natural blending pH adjusters which is synergistic effect or natural blending pH adjusters which is synergistic effect mixing with radish juice were mung bean+peas(272), mung bean+soy bean(282), fungus+parsley(302), Garlan chrysanthenum+amaranth(300), Garland chrysanthenum+wild sesame leaf(277), amaranth+green pepper(300) and amaranthe+parsley(280) etc and those mixing with cabbage juice were peas+fungus(202), Garland chrysanthenum(207) and fungus+parsely (205) etc.

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Frontal Face Region Extraction & Features Extraction for Ocular Inspection (망진을 위한 정면 얼굴 영역 및 특징 요소 추출)

  • Cho Dong-Uk;Kim Sun-Young
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.6C
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    • pp.585-592
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    • 2005
  • One of the most important things in the researches on diseases is to attach more importance to prevention of a disease and preservation of health than to treatment of a disease, also to foods rather than to medicines. In this context, the most significant concern in examining a patient is to find the presence of disease, and, if any, to diaguose the type of disease, after which a pharmacotherapy is followed. In this paper, various diagnosis methods of Oriental medicines are discussed. And ocular inspection, the most important method among the 4 disease diagnoses of Oriental medicines, is studied. Observing a person's shape and color has been the major method for ocular inspection, which usually has been dependent upon doctor's intuition as of these days. We are developing an automatic system which provides objective basic data for ocular inspection. As the first stage, we applied the signal processing techniques to automatic feature extraction of faces for ocular inspection. Firstly, facial regions are extracted from the point of frontal view, which was followed by extraction of their features. The experiment applied to 20 persons showed that frontal face regions are perfectly extracted, as well as their features, such as eyes, eyebrows, noses and mouths. Future work will seek to address the issues of morphological operation for a few unfinished extraction results, such as combined hair and eyebrows.

The Study of Magnetic Properties of Ni-Zn-Cu Ferrite by variation of Low Temperature Sintered (저온소결 온도변화에 따른 Ni-Zn-Cu 페라이트의 자기적 특성 연구)

  • Koh, Jae-Gui
    • Journal of the Korean Magnetics Society
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    • v.17 no.6
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    • pp.232-237
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    • 2007
  • We have synthesized the low temperature sintered of Ni-Zn-Cu ferrite with nonstoichiometric composition a little deficient in $Fe_2O_3$ from $(Ni_{0.2}Cu_{0.2}Zn_{0.6})_{1+x}(Fe_2O_3)_{1-x}$. For low loss and acceleration of grain growth $TiO_2$ and $Li_2CO_3$ was added from 0.25 mol% to 1.0 mol%. The mixture of the law materials was calcinated and milled. The compacts of toroidal type were sintered at different temperature $(875^{\circ}C,\;900^{\circ}C,\;925^{\circ}C\;950^{\circ}C)$ for 2 hours in air followed by an air cooling. Then, effects of composition and sintering temperatures on the physical properties such as density, resistivity, magnetic induction, coercive force, initial permeability, and quality factor of the Ni-Zn-Cu ferrite were investigated. The density of the Ni-Zn-Cu ferrite was $4.85\sim5.32g/cm^3$, resistivity revealed $10^8\sim10^{12}\Omega-cm$. The magnetic properties obtained from the aforementioned Ni-Zn-Cu ferrite specimens were 1,300 gauss for the maximum induction, 4.5 oersted for the coercive force, 275 for the initial permeability, and 83 for the quality factor. The physical properties indicated that the specimens could be utilized as the core of high frequency range (involved microwave range) communication and deflection yoke of T.V.