• Journal of Food Hygiene and Safety
• /
• v.5 no.4
• /
• pp.187-196
• /
• 1990

This study was carried out to develop new model for gastric ulcer and to investigate some factor which effect it. Rats were immersed for 8 hours. Ulcer index was measured from total length of occured ulcer. Ulcer index (UI) of restraint and immersion group was higher significantly than that of only restraint group (p<0.001) and ulcer was occurred within only glandular stomach. UI of low water temperature group was higher significantly than that of high water temperature group (p

• Physical Therapy Korea
• /
• v.8 no.4
• /
• pp.45-61
• /
• 2001

본 연구는 보행주기 동안 정상인과 당뇨병성 족부궤양 환자의 족관절 운동역학적 변수와 족관절 근육들의 근활성도에 차이가 있는지 알아보기 위하여 실시하였다. 본 연구의 대상자는 당뇨병성 족부궤양이 있는 환자 9명(남자: 6명, 여자: 3명)과 성, 연령, 체중으로 짝짓기(matching)시킨 대조군 9명이었다. 3차원 동작분석기, 힘판, 표면 근전도를 이용하여, 보행주기 동안 족관절의 관절가동범위, 모멘트(moment), 일률(power), 그리고 내측가자미근, 전경골근, 비복근의 근수축 개시시간(onset time)과 종료시간(cessation time)을 측정하였다. 정상군과 비교하여 당뇨병성 족부궤양군의 보행속도는 느렸고, 입각기 기간이 길었으며, 족관절의 가동범위가 적었고, 족관절 최대 족저굴곡 모멘트와 일률이 정상군에서보다 유의하게 낮았다. 보행주기에서 당뇨병성 족부궤양군에서 내측 가자미근과 비복근의 근수축 개시시간은 유의하게 빨랐으며, 전경골근과 비복근의 근수축 종료시간은 유의하게 지연되었다. 당뇨병성 족부궤양 환자군의 족관절 근육에서 동시수축(co-contraction)이 증가되고, 보행속도가 느리며, 입각기 기간이 증가하였다. 이러한 보행특성의 차이는 족부 감각손실에 따른 보행의 안정성을 유지하기 위한 보행전략 때문으로 판단된다. 앞으로 이러한 비정상적인 보행특성이 당뇨병성 족부궤양에서 발생하는 비정상적인 족저부 압력분포과 족부궤양 발생과 어떤 관계가 있는지 알아보는 연구가 필요할 것이다.

• Research in Plant Disease
• /
• v.23 no.1
• /
• pp.1-18
• /
• 2017

Pseudomonas syringae pv. actinidiae, the causal agent of bacterial canker, is currently causing severe economic losses to kiwifruit production worldwide. The pathogen has affected green-fleshed kiwifruit cutlivars and yellow-fleshed kiwifruit cultivars since 1988 and 2006 in Korea, respectively. In recent years, the biovar 3 strains of P. syringae pv. actinidiae were introduced through imported contaminated pollens and have rapidly spread to neighboring kiwiruit orchards by secondary infection, leading to outbreaks of bacterial canker and tremendous damages on yellow- and red-fleshed kiwifruit cultivars. In this review, we summarize the various management practices of bacterial canker of kiwifruit such as disease escaping, cultural practices, blocking of dissemination, early diagnosis, eradication of inoculum sources, chemical control, and trunk injection on the basis of our research works and field experiences and important research products conducted during the last three decades in the world. Finally, we propose a manual for the efficient management of the disease that can be practically utilized at the farmers' orchards in order to keep kiwifruit vines healthy in the future.

• Proceedings of the KSCN Conference
• /
• 1997.10a
• /
• pp.51-51
• /
• 1997

• Journal of Oral Medicine and Pain
• /
• v.30 no.3
• /
• pp.319-328
• /
• 2005

To examine whether HSV, VZV, H. pylori and Candida that are known to be microorganisms causing ulcerative disease in oral cavity and have the relatively high contigiousness are detected in saliva of patients with RAU and related to the development with RAU, PCR and culture were performed on the saliva of 29 patients with RAU and 29 control subjects who visited the Department of Oral Medicine, Dental Hospital, Chosun University. The results were obtained as follows; 1. HSV DNA was detected in 41.4% patients with RAU, and 55.2% control subjects, however, a significant difference between the two groups was not detected, (P>0.05), and VZV DNA was not detected in both groups. 2. H. pylori DNA was detected in 27.6% patients with RAU, and 48.3% control subjects, however, a significant difference between the two groups was not detected (P>0.05). 3. Candida was cultured in 13.8% patients with RAU, and 6.9% control subjects, however, a significant difference between the two groups was not detected (P>0.05). This results suggest that HSV, VZV, H. pylori and Candida can not be regarded to play a direct role in the development of RAU. Thus it is considered that in future, on a larger sample, also, it has to be examined whether other microorganisms acts as a trigger factor of the development of RAU.

• The Journal of the Korean bone and joint tumor society
• /
• v.18 no.1
• /
• pp.1-6
• /
• 2012

Purpose: The purpose of this study was to analyze the results of treatment and prognosis of Marjolin's ulcer compared with primary squamous cell carcinoma. Materials and Methods: Fourteen patients treated for Marjolin's ulcer were analyzed. Twenty patients with primary squamous cell carcinoma treated during the same time period was the control group. Mean age was 61.2 years. There were 24 males and 10 females. The locations, TNM stages, histological grades, recurrence, metastasis, and survival rate were analyzed and compared between two groups. Results: The mean follow-up period was 54.8 months (range, 12-168 months). Local recurrences were found in 6 cases, 5 ones in Marjolin's ulcer patients, and one case in primary squamous cell carcinoma patients. The mean time interval between the initial presentation and occurrence of local recurrences was 9 months (range, 2-20 months). There were 6 metastases. 2 (14.3%) metastases were found in Marjolin's ulcer patients, and 4 (20.0%) metastases in primary squamous cell carcinoma patients. Total events (metastasis or local recurrence) were found in 10 pateients, 6 of them in Marjolin's ulcer group, and the remaining four in primary group. 5-year disease-free survival rate was 64.3% in Marjolin's ulcer group and 95.0% in primary squamous cell carcinoma group. Conclusion: Squamous cell carcinomas originating as Marjolin's ulcers revealed higher recurrence rate and lower survival rate despite of aggressive treatment. Therefore, new treatment modalities should be developed for improving outcomes.

• Journal of Oral Medicine and Pain
• /
• v.34 no.1
• /
• pp.55-62
• /
• 2009

In most cases, it is difficult to diagnose ulcerative diseases of the mouth, because they have many similar clinical appearance. For the diagnosis of oral ulcerative lesions, the clinician should check a detailed history of the patient and consider the relation with systemic diseases. In this case report, we introduced two patients with erythematous multiforme, phemphigus, lichenoid reaction and aphthous stomatitis as clinical diagnosis. The lesions were improved by medication.

• Parasites, Hosts and Diseases
• /
• v.32 no.3
• /
• pp.201-204
• /
• 1994

Echinostomiasis is an endemic intestinal trematodiasis of humans in Korea We observed a human case of Echinostomn honense infection who had ulcerations on the duodenal mucosa. A 55-year old man living in Hamyang-gun, Kyongnam, complained of epigastric pain with hematemesis In April 1994. Endoscopy revealed lesions of early gastric cancer and duodenal ulcerations. A penetrating parasite into the duodenal mucosa was picked out, and identified as E. honense. As the patient was treated 10 praziquantel 10 mg/kg single dose,3 more E. hofene and 7 Metogonimw worms were recovered. This case demonstrates that echinostomiasis causes gross ulcerations in the duodenum.

• The Monthly Diabetes
• /
• s.289
• /
• pp.26-36
• /
• 2013

'당뇨발'은 '당뇨환자에서 신경학적 이상이나 말초혈관 이상 때문에 발생하는 발의 궤양으로 감염이나 심부 조직의 파괴를 동반하기도 하는 발의 질병'이라고 정의할 수 있다. 하지만 실제로는 발에 궤양이 발생한 상태가 아니더라도 매우 포괄적인 용어(umbrella term)로서 당뇨병환자에게서 발생하는 발의 만성 합병증을 총칭하는 것이 일반적이다. 왜냐하면 발의 궤양을 동반하지 않는 괴저(괴사), 심부 감염, 신경병증성 관절증(Charcot arthropathy) 등도 당뇨발의 범주에 포함시켜야 하기 때문이다. 이렇게 보면 '당뇨발'이란 의학적 진단명으로는 적절하지 않은 용어라 할 수도 있다. 다만 이미 일반화된 용어로서 환자의 교육과 설명에는 더 유용하다고 할 수 있다.

• The Journal of the Korean dental association
• /
• v.21 no.6 s.169
• /
• pp.449-452
• /
• 1983

구강내에서 발생하는 연조직 질환중 궤양을 수반하여 환자로 하여금 통증을 호소하게 하는 질환으로는 급성 괴사성 궤양성 치간염 (Acute Necrotizing Ulcerative Gingivitis), 급성 수포성 구내염(Acute Herpetic Gingivo Stomatitis), 재발성 구순포진(Recurrent Herpes Labialis), 재발성 아프타성 구내염(Recurrent Aphthous Stomatitis), 대상성 포진(Herpes Zoster) 등이 있으며, 다른 질환보다도 그 발생빈도가 높아 임상에서 접하게 되며 그 치유속도가 늦어 가끔 당혹감을 느끼는 수가 있다. 이들 질환의 임상적 소견과 그 질환에 대한 치료법의 예를 간략하게 생각해 보고져 한다.