• Title/Summary/Keyword: 국소화

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질병 - 분무접종법에 대한 올바른 이해

  • Park, Jeong-Yong
    • Monthly Korean Chicken
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    • v.16 no.6
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    • pp.124-126
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    • 2010
  • 양계인이라면 누구나 생독백신 접종 후에 나타나는 백신접종반응(기침 등 호흡기 증상)은 적으면서 백신접종효능(항제 형성능 및 질병방어효과)은 아주 우수한 그런 종류의 생독 백신이나 접종법을 찾게 마련이다. 국내의 경우 1일령 병아리에 대한 닭 뉴캣슬병 생독백신 접종이 의무화되어 있어 부화장에서 병아리 분양 시 분무백신기를 이용한 닭 뉴캣슬병 생독백신을 접종하게 되고, 또한 농장에서 닭 뉴캣슬병 추가백신 접종이나 닭 전염성 기관지염 백신 접종 시에도 분무접종을 실시하기도 하는 등 분무접종에 대한 경험은 누구나 가지고 있을 것이다. 그러나 음수접종법과 달리 분무접종 시 심한 백신접종반응을 경험하게 되는 양계인들도 쉽게 만나볼 수 있다. 생독백신은 음수접종법을 비롯하여 점안접종법 및 분무접종법 등 다양한 접종방법이 현재 야외농장에서 응용되고 있으며, 국내 육계사육 시에는 음수접종법과 분무접종법이 주로 사용되고 있다. 하지만 동일한 종류의 생독백신이라 할지라도 백선접종방법에 따라 백신접종 후 백신접종효능뿐만 아나라 백신접종반응에도 많은 차이를 보이게 되며 동일한 분무접종법이라 하더라도 어떠한 입자 크기의 분무기를 사용했는가에 따라서도 이러한 차이는 있다. 분무접종은 백신 바이러스가 비강,눈(harderian gland) 뿐만 아니라 상부 호흡기도에 직접적으로 작용을 하여 강력함 국소면역능을 유발하는 장점을 가지고 있으나 접종일령이나 접종 백신의 종류를 고려한 분무입자 크기의 선택이 제대로 이루어지지 않아 음수접종법에 비해 접종 부작용이 크게 나타나는 백신접종법으로 인식되어 있는 실정이다. 따라서 이번 호에서는 호흡기 질병의 예방 백신 분무접종에 대해 알아보고자 한다.

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Analysis of Micro- to Macro-Mechanics in Granitic Rock: Experimental Observation and Theoretical Consideration (화강암질암에 대한 미시적에서 거시적 손상역학의 해석 : 실험 및 이론)

  • Jeong, Gyo-Cheol
    • Economic and Environmental Geology
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    • v.27 no.5
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    • pp.499-505
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    • 1994
  • Local stress concentrations often cause new micro-damaging induced by a healed pre-existing defects, and the macro-damage is developed by propagation and coalescence of the micro-damage. The micro-damage causes non-linear deformation in rock material. Considerable work has also been applied to describe mathematically the behavior of cracks under stress. Although these mathematical models can usually be made to agree quite well with the measured data, but it is questionable how well the models describe real rock including microcracks in pre-failure state, such as their micro-damage mechanisms. In the present study, micro-damage initiation and propagation in granitic rock under increasing stress were observed directly. Furthermore, a stress analysis considering the bisphere model was carried out using the homogenization theory to analyze the mechanics of the stress-induced micro-damage.

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Local hydrogel patterning and microcantilever fabrication using dynamic mask lithography (동적 마스크 리소그래피를 이용한 하이드로젤 국소 패터닝 기법과 캔틸레버 제작)

  • Lee, Jungchul;Lee, Il
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2013.04a
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    • pp.809-809
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    • 2013
  • We report a new method for highly controllable local patterning of a hydrogel on microfabricated cantilevers and fabrication of all hydrogel microcantilevers. We constructed a dynamic mask based photolithography setup using a commercial beam projector, a 3-axis microstage and other optical components. Dynamic masks generated from the beam projector controlled the shape, size, and position of hydrogel patterns while the 3-axis microstage mainly controlled the thickness of hydrogel patterns and hydrogel microcantilevers. Using the constructed setup, polyethyleneglycol diacrylate (PEGDA) was patterned on microfabricated cantilevers in a highly controlled manner. Currently, the smallest PEGDA patternable is a 5-${\mu}m$-diameter circle with a thickness of ~$10{\mu}m$. To confirm thicknesses of patterned PEGDAs on silicon microcantilevers, resonance frequencies of microcantilevers were measured before and after each PEGDA patterning. Thicknesses extracted from resonance measurements showed good agreement with measurements using an optical microscope. In addition, PEGDA microcantilevers with various dimensions and thicknesses were fabricated on glass and silicon substrates. Surfaces of fabricated all hydrogel microcantilevers were flat enough to facilitate other post processing and to be used for various sensing applications.

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Joint Optimization of Source Codebooks and Channel Modulation Signal for AWGN Channels (AWGN 채널에서 VQ 부호책과 직교 진폭변조신호 좌표의 공동 최적화)

  • 한종기;박준현
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.6C
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    • pp.580-593
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    • 2003
  • A joint design scheme has been proposed to optimize the source encoder and the modulation signal constellation based on the minimization of the end-to-end distortion including both the quantization error and channel distortion. The proposed scheme first optimizes the VQ codebook for a fixed modulation signal set, and then the modulation signals for the fixed VQ codebook. These two steps are iteratively repeated until they reach a local optimum solution. It has been shown that the performance of the proposed system can be enhanced by employing a new efficient mapping scheme between codevectors and modulation signals. Simulation results show that a jointly optimized system based on the proposed algorithms outperforms the conventional system based on a conventional QAM modulation signal set and the VQ codebook designed for a noiseless channel.

A Study on the Phoneme Segmentation of Handwritten Korean Characters by Local Graph Patterns on Contacting Points (접촉점에서의 국소 그래프 패턴에 의한 필기체 한글의 자소분리에 관한 연구)

  • 최필웅;이기영;구하성;고형화
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.30B no.4
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    • pp.1-10
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    • 1993
  • In this paper, a new method of phoneme segmentation of handwritten Korean characters using the local graph pattern is proposed. At first, thinning was performed before extracting features. End-point, inflexion-point, branch-point and cross-point were extracted as features. Using these features and the angular relations between these features, local graph pattern was made. When local graph pattern is made, the of strokes is investigated on contacting point. From this process, pattern is simplified as contacting pattern of the basic form and the contacting form we must take into account can be restricted within fixed region, 4therefore phoneme segmentation not influenced by characters form and any other contact in a single character is performed as matching this local graph pattern with base patterns searched ahead. This experiments with 540 characters have been conducted. From the result of this experiment, it is shown that phoneme segmentation is independent of characters form and other contact in a single character to obtain a correct segmentation rate of 95%, manages it efficiently to reduce the time spent in lock operation when the lock.

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Study on the Performance Improvement of Roof Fan Used for Local Exhaust System Installed in Apartment (공동주택의 국소배기용 루프팬 성능개선에 관한 연구)

  • Kwon, Yong-Il;Jeong, Yeol-Wha;Ahn, Jung-Hun
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.24 no.2
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    • pp.136-141
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    • 2012
  • Performance improvement of local exhaust system used in toilet and cooking place are main concern in a field of ventilation. In Korea, There are many high riser residential apartments in recent years. These buildings were not viewed as being major contributors to exhaust pollutants producted in indoor. It was because many engineers thought that exhaust in high riser building depends on stack effect. This study investigates on the performance improvement of terminal device, roof fan, of vertical spiral duct used in high riser residential apartments. This paper focuses mainly on the effect of accessories, number or shape of blades, composed of roof fan with function of exhaust air volume of toilet and cooking place. Roof fan with 10 blades is observed at optimum exhaust performance in this study.

Body Distribution of $^{125}I-rhEGF$ Across Normal and Damaged Rat Skins (정상 및 손상된 흰쥐 피부에 국소 적용된 $^{125}I-rhEGF$의 체내 이행)

  • Lee, Jeong-Uk;Chung, Suk-Jae;Lee, Min-Hwa;Shim, Chang-Koo
    • YAKHAK HOEJI
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    • v.41 no.6
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    • pp.730-736
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    • 1997
  • Distribution of radioactivity in the skin tissues, subcutaneous tissues, blood and body organs was examined following topical application of $^{125}I-rhEGF$(0.4 ${\mu}Ci$), in the form of a Pluronic F-127 gel, on the normal and damaged (burned and stripped) skins of SD male rats. The radioactivity in the skin tissues and subcutaneous tissues was 3-5 times higher for the damaged skins than for the normal skin. But pretreatment of the skin with rhEGF (1${\mu}g$)) twice at 24 hr dose intervals affected the distribution of the radioactivity yielding the order of burned skin> stripped skin=normal skin. The decrease for the stripped skin by the pretreatment might be related either to the pathophysiological change of the skin or to the down regulation of the EGF receptor. Liver showed the highest radioactivity in amount following single and multiple administration of the drug to the normal and damaged skins. But,in concentration, the kidney and stomach showed higher value than the liver which is consistent with that kidney is a major eliminating organ of EGF and that EGF exerts its pharmacological effect specifically for the stomach.

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A Case of the Laryngeal Papilloma Observed for the Past 13 Years (13년간 경과를 관찰한 후두유두종의 1예)

  • 이양선;박윤이;이인환
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1983.05a
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    • pp.5.2-5
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    • 1983
  • It is well known that laryngeal papilloma is histopathological benign, but clinically one of the most troublesome disease in otolaryngologic department, usually seen in child age. Since Cleesmann reported papilloma of the vocal cord, 1817 first, the etiology had not been known exactly. The symptoms in children are dyspnea, dysphonia due to recurrence, and papilloma in adult can change into neoplasm. The papilloma is thought as real neoplastic lesion and there is not effective treatment, using now repeated removal and combined therapy. This report is based on the typical findings and progress of one case of laryngeal papilloma observed for the past 13 years with repeated removal and topical application of 5-FU at our department. Authors have experienced this subject is interesting that the change of the tumor region during the course than to any new therapeutic methods employed, and so report with some reviews of the literatures.

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Potential of Fuel Stratification for Reducing Pressure Rise Rate in HCCI Engines (HCCI 기관에 있어서의 층상 흡기를 통한 압력 상승률 저감에 대한 연구)

  • Lim, Ock-Taeck
    • Journal of the Korean Institute of Gas
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    • v.14 no.6
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    • pp.7-14
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    • 2010
  • This study investigated the effect on reducing the pressure rise rate(PRR) in HCCI Engine by the variation of mixing ratio in the pre-mixture of DME and n-Butane that has different auto-ignition characteristics. In addition to measure of gas pressure in the engine cylinder, chemiluminescence image using the optical accessible engine and numerical analysis with multi-zones model were used to assess the combustion at each local area in the combustion chamber. The maximum PRR changes depending on mixing condition of DME and n-Butane. When DME is stratified and n-Butane is distributed uniformly, maximum PRR becomes lowest which is about 0.25MPa/ms and it corresponds to 5deg. retarding of CA50.

심플렉틱 다양체의 불변량

  • 조용승
    • Communications of the Korean Mathematical Society
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    • v.15 no.3
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    • pp.391-434
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    • 2000
  • 심플렉틱 구조는 국소적으로는 모두 같기 때문에 심플렉틱 다양체 연구는 대역적으로 연구해야한다. 그로모브가 복소해석학적 곡선을 원소를 하는 모률라이 공간의 연구가 심플렉틱 다양체를 연구하는 물고를 텃다. 특이점이 없는 복소곡선의 개수를 세는 그로모브 불변량은 도넬슨의 비선형 게이지 이론의 간략화라 할 수 있는 아벨리안게이지 이론에서 사이버그-위튼 불변량과 같음을 타우브스가 발견하였다. 또한 사이버그-위튼 불변량은 심플렉틱 다양체의 불변량으로 심플렉틱 구조연구에 큰 이바지하고 있다. 그로모브의 모듈라이 공간의 컴펙트하는 과정에서 자연스럽게 마크점과 특이점을 갖는 곡선의 그로모브-위튼 모듈라이 공간이 켐펙트가 되고 여기소 그로모브-위튼 불변량이 얻어진다. 이 그로모브-위튼 불변량은 대수기하와 이론 물리학의 끈이론에서 찾는 대수곡선의 개수를 나타내고, 코호몰로지의 컵곱의 일반화라 할 수 있는 퀸텀곱을 유도하고, 그로모브-위튼 포텐셜함수의 계수를 결정한다. 퀸텀곱의 결합법칙은 포텐셜함수의 WDVV-방정식과 동치를 나타나며 이는 프로베니우스 구조가 평탄함을 나타낸다. 그로모브-위튼 불변량은 앞으로 활발히 연구되고 수학에 광범하게 이바지 할 것이다.

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