• Title/Summary/Keyword: 국소화

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Hand-Foot syndrome induced by sorafenib, a multitargeted tyrosine kinase inhibitor, in a patient with advanced renal cell carcinoma (진행된 신세포암 환아에게 sorafenib 투여시 발생한 Hand-Foot syndrome 1예)

  • Lee, Seung Hyun;Noh, Sung Hun;Kim, Sun Young;Jang, Kyu Yun;Hwang, Pyoung Han
    • Clinical and Experimental Pediatrics
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    • v.52 no.1
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    • pp.119-123
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    • 2009
  • Renal cell carcinoma (RCC) arising from epithelial cells of the renal tubules is a highly aggressive and malignant tumor in all ages; however, it rarely occurs in children. the standard treatment for RCC is radical nephrectomy with lymph node dissection when the tumor is localized and can be completely resected. Adjuvant chemotherapy, radiotherapy, and immunotherapy are used for pediatric patients with advanced RCC involving lymph nodes or metastatic lesions. Sorafenib is an oral, multikinase inhibitor that has recently been approved for use in metastatic RCC. Common toxicities that have been reported include dermatologic changes such as rash or desquamation and hand-foot skin reaction, diarrhea, fatigue, alopecia, and hypertension. In particular, hand-foot syndrome (HFS) an erythematous skin lesion of the palms and solesis most often caused by cytostatic chemotherapeutic agents. In this report, we have studied a 14-year-old female patient with hand-foot syndrome that occurred in association with sorafenib for the treatment of metastatic RCC. Furthermore, this case demonstrates that reversal of complications can be achieved by discontinuing the drug and intervention with topical steroids, vitamin E, and high-dose pyridoxine.

Titre- l'économie trans libidinale-homo surplus (트랜스 리비도 경제학 - Homo surplus)

  • Yun, Ji-yeong
    • Journal of Korean Philosophical Society
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    • v.126
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    • pp.191-212
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    • 2013
  • Cet article consiste ${\grave{a}}$ critiquer $l'{\acute{e}}conomie$ libidinale, $subordonn{\acute{e}}e$ ${\grave{a}}$ l'ordre phallique qui coupe les flux libidinaux. La notion lacanienne du $d{\acute{e}}sir$ qui est $focalis{\acute{e}}e$ sur le manque, ne pourrait prendre en compte la dimension $cr{\acute{e}}ative$ et productive du $d{\acute{e}}sir$ qui est $li{\acute{e}}e$ ${\grave{a}}$ la perspective deleuzienne et guattarienne du $d{\acute{e}}sir$. La $possibilit{\acute{e}}$ de la $d{\acute{e}}rive$ et de la $d{\acute{e}}stratification$ des flux libidinaux pourrait se mener vers la notion du "homo surplus", laquelle est la notion $in{\acute{e}}dite$ que j'ai $cr{\acute{e}}e$. Le surplus est ce qui $d{\acute{e}}passe$ la logique phallogocentrique par son $immensurabilit{\acute{e}}$ et sa surabondance. Dans cette perspective, la critique virulente de la notion du plaisir $cantonn{\acute{e}}$ dans la partie $g{\acute{e}}nitale$, $s^{\prime}op{\grave{e}}re$ avec l'analyse de la jouissance qui est non phallique; Cette jouissance non phallique est $li{\acute{e}}e$ ${\grave{a}}$ l'agencement non $lin{\acute{e}}aire$ et multiple des pratiques sexuelles $in{\acute{e}}dites$ et radicales.

Morphological Interpretation of Modified Karhunen-Loeve Transformation and Its Applications to Color Image Processing (변형 Karhunen-Loeve 변환의 수리형태학적 의미와 칼라 영상처리에의 응용)

  • Eo, Jin-Woo
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.31B no.11
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    • pp.97-108
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    • 1994
  • A modified Karhunen-Loeve transformation technique using normalization and simultaneous diagonalization of two sample covariance matrices is proposed to separate the object from the background. The transformation technique for the separation of local data structure through maximizing the ratio of sample variances between two classes was identified as a promising one for a preprocessing of multi-variate signal processing algorithms using neighborhood operators including morphological filtering. To relate the separation quality of the proposed technique to a morphological measure, average height was defined by using morphological pattern spectrum. A practical implementation of the transformation technique was tested experimentally and the theoretical results were confirmed.

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Measurements of Equivalence Ratio in the Spark Plug Gap and Its-Effects on Combustion Under Stratified Mixture Conditions in a Constant Volume Chamber (정적 연소실에서 성층화된 혼합기 조건하의 점화 전극사이 당량비 측정과 연소 특성에 미치는 영향)

  • Bae, Sang-Su;Lee, Gi-Cheol;Min, Gyeong-Deok
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.25 no.10
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    • pp.1311-1317
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    • 2001
  • To investigate only the effects of the stratified mixture distribution on initial flame propagation and combustion characteristics, the instantaneous equivalence ratio in the spark plug gap and combustion pressure were measured simultaneously In a constant volume chamber, To induce the stratified propane-air mixture distribution near the spark plug, counter-flow typed mixture injection system was used under the constant mean equivalence ratio $\Phi$$\_$mean/= 1.0 The instantaneous equivalence ratio was measured by a single-shot Raman scattering with narrow-band KrF excimer laser. The measuring error was within the limit of $\pm$ 3.5% provided that the proposed method was applied to the measured Raman signals. Judging from mass fraction burned derived from the measured pressure, the optimum combustion characteristics were shown under the condition that the local equivalence ratio in the spark plug was near 1.28$\pm$0.04, and these characteristics were more remarkable at the initial stage of combustion.

Renal Biopsy (신장의 조직 검사)

  • Taek Min Kim;Jeong Yeon Cho;Sang Youn Kim
    • Journal of the Korean Society of Radiology
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    • v.84 no.6
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    • pp.1198-1210
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    • 2023
  • The extent of renal biopsy indication is being widened because of the increasing incidence of incidental renal masses; the increasing treatment options for renal cell carcinoma, including ablation therapy and novel targeted treatment; and the increasing incidence of kidney transplantation. However, percutaneous renal biopsy is technically difficult, particularly for beginners, because the skin-to-organ distance is relatively longer than those associated with other organs. In the present review, we will discuss the indications, technical considerations, efficacy, and complications of renal biopsy. Furthermore, we share practical tips of renal biopsy through many examples to help radiologists perform renal biopsy safely and effectively in various situations.

On the Extension of Test Statistics for Detecting Negative Binomial Departures from the Poisson Assumption (포아송으로부터 부의 이항분포로의 이탈에 대한 검정통계량의 확장)

  • 이선호
    • Journal of the Korean Statistical Society
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    • v.22 no.2
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    • pp.171-190
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    • 1993
  • 포아송분포로부터 부의 이항분포로의 이탈을 검색하는 통계량들이 자료의 형태에 따라 여러가지 제시되었다. 그런데 대립가설인 부의 이항분포의 모수화 방법에 따라 분산과 평균의 구조가 변하고 국소 최적 검정 통계량도 달라진다는 것이 알려졌다. 본 논문에서는 대립가설을 일반적인 포아송 혼합분포로까지 확장시키고, 일반적인 형태의 분산과 평균의 구조에도 검정 가능한 새로운 통계량 L을 소개하고 있다. 또한 L 통계량은 포아송 분포로부터 부의 이항분포로의 이탈을 다루는 기존의 여러 통계량들의 일반화된 형태임을 보였다. 점근적 상대효율과 모의 실험을 통하여 L 통계량과 기존의 통계량들을 비교한 결과 분산과 평균사이의 구조에 상관없이 L 통계량이 우수한 것임을 입증하였다.

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Decision-Making System for Optical Transmission Line Management and Design (광전송로 관리 및 설계에 더한 의사 결정 시스템)

  • Yoon Kyeong-Mo;Lee Yong-Gi;Song Kil-Ho
    • 한국정보통신설비학회:학술대회논문집
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    • 2002.08a
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    • pp.130-132
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    • 2002
  • 기존의 광선로 특성 데이터에 대한 관리는 대부분 지역별 국소별로 수작업에 의존하였기 때문에 처리 절차의 일원화 및 체계화가 제대로 정립되어 있지 않았다. 이로 인해 선로 자원의 사용이 원활하지 못하였고 최적의 망을 구축하는데 많은 시간 인력 및 비용이 소요되는 등 비효율적인 문제점들이 도출 되었다. 이러한 문제점을 해결하기 위해 본 논문에서는 수작업에 의존했던 광 전송로의 특성 정보를 데이터베이스화하여 데이터에 대한 다양한 가공 능력 및 투자에 대한 일관성 있는 의사 결정 능력을 제시하였으며, 구축된 데이터베이스를 통해 최적의 광통신망 설계를 지원할 수 있도록 광전송로 관리 및 설계 처리에 대한 의사 결정 시스템을 제안했다.

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Instability Analysis of Natural Convection Flow along Isothermal Vertical Cylindrical Surfaces (등온 수직 원통표면을 연하여 흐르는 자연대류 유동의 파형 불안정성)

  • 유정열;윤준원;노승탁
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.13 no.1
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    • pp.161-169
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    • 1989
  • A stability problem on wave instability of natural convection flow along isothermal vertical cylindrical surfaces has been formulated, accounting for the non-parallelism of the basic flow and thermal fields. Then the problem is solved numerically under the simplifying assumption of the parallelism of the basic flow quantities. It is shown that the flow corresponding to the same characteristic boundary layer thickness becomes more stable as the value of the curvature parameter increases. The stability characteristics for Pr=0.7 appear to be more sensitive to the curvature parameter than those for Pr=7.

A CASE OF LARYNGEAL STENOSIS TREATED WITH $CO_2$ LASER ($CO_2$ Laser에 의한 후두협착증의 치험예)

  • 김영숙;이종욱;강경화;김춘길;주양자
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1987.05a
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    • pp.19.3-20
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    • 1987
  • 후두협착증은 그동안 여러 치료방법에도 불구하고 이비인후과영역에서 가장 어려운 문제 중의 하나로 남아 있다. 1979년 McGee등이 후두 및 기관협착증에 처음으로 $CO_2$ laser를 사용한 이래 미세현미경술과 조화되어 후두의 상흔 및 육아조직을 제거하는 정교하고, 쉽고, 지혈이 우수한 방법으로 대두되고 있다. 또한, 주기적인 후두 및 기관확장술, 국소 steroid주입법, stenting등의 보조요법과 병행하여 사용될 때 개방성형술의 빈도를 훨씬 줄일 수 있다. 최근 저자들의 상흔성 비후에 의한 후두협착 환자에서 $CO_2$ laser를 사용하여 협착을 제거하여 좋은 결과를 얻었기에 문헌고찰과 함께 보고하는 바이다.

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Stroke Extraction of Chinese Character using Mechanism of Optical Neural Field (시각신경 메커니즘을 이용한 한자 획의 분리 및 추출)

  • Son, Jin-U;Lee, Uk-Jae;Lee, Haeng-Se
    • The Transactions of the Korea Information Processing Society
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    • v.1 no.3
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    • pp.311-318
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    • 1994
  • In this paper, a new stroke extraction method of Chinese character base on the human optical field(the Receptive Field of Cell) is proposed. In processing the feature extraction of the chinese character, needed are more perfect extraction methods for separated informations and its data base. This method can be applied to processing neural cell using conventional feature extraction mechanism in the optical boundary of retina and cerebrum. With this method, its applicability and effectiveness were demonstrated extracting strokes from Chinese character.

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