• Title/Summary/Keyword: 국소화

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Local hydrogel patterning and microcantilever fabrication using dynamic mask lithography (동적 마스크 리소그래피를 이용한 하이드로젤 국소 패터닝 기법과 캔틸레버 제작)

  • Lee, Jungchul;Lee, Il
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2013.04a
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    • pp.809-809
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    • 2013
  • We report a new method for highly controllable local patterning of a hydrogel on microfabricated cantilevers and fabrication of all hydrogel microcantilevers. We constructed a dynamic mask based photolithography setup using a commercial beam projector, a 3-axis microstage and other optical components. Dynamic masks generated from the beam projector controlled the shape, size, and position of hydrogel patterns while the 3-axis microstage mainly controlled the thickness of hydrogel patterns and hydrogel microcantilevers. Using the constructed setup, polyethyleneglycol diacrylate (PEGDA) was patterned on microfabricated cantilevers in a highly controlled manner. Currently, the smallest PEGDA patternable is a 5-${\mu}m$-diameter circle with a thickness of ~$10{\mu}m$. To confirm thicknesses of patterned PEGDAs on silicon microcantilevers, resonance frequencies of microcantilevers were measured before and after each PEGDA patterning. Thicknesses extracted from resonance measurements showed good agreement with measurements using an optical microscope. In addition, PEGDA microcantilevers with various dimensions and thicknesses were fabricated on glass and silicon substrates. Surfaces of fabricated all hydrogel microcantilevers were flat enough to facilitate other post processing and to be used for various sensing applications.

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Joint Optimization of Source Codebooks and Channel Modulation Signal for AWGN Channels (AWGN 채널에서 VQ 부호책과 직교 진폭변조신호 좌표의 공동 최적화)

  • 한종기;박준현
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.6C
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    • pp.580-593
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    • 2003
  • A joint design scheme has been proposed to optimize the source encoder and the modulation signal constellation based on the minimization of the end-to-end distortion including both the quantization error and channel distortion. The proposed scheme first optimizes the VQ codebook for a fixed modulation signal set, and then the modulation signals for the fixed VQ codebook. These two steps are iteratively repeated until they reach a local optimum solution. It has been shown that the performance of the proposed system can be enhanced by employing a new efficient mapping scheme between codevectors and modulation signals. Simulation results show that a jointly optimized system based on the proposed algorithms outperforms the conventional system based on a conventional QAM modulation signal set and the VQ codebook designed for a noiseless channel.

A Study on the Phoneme Segmentation of Handwritten Korean Characters by Local Graph Patterns on Contacting Points (접촉점에서의 국소 그래프 패턴에 의한 필기체 한글의 자소분리에 관한 연구)

  • 최필웅;이기영;구하성;고형화
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.30B no.4
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    • pp.1-10
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    • 1993
  • In this paper, a new method of phoneme segmentation of handwritten Korean characters using the local graph pattern is proposed. At first, thinning was performed before extracting features. End-point, inflexion-point, branch-point and cross-point were extracted as features. Using these features and the angular relations between these features, local graph pattern was made. When local graph pattern is made, the of strokes is investigated on contacting point. From this process, pattern is simplified as contacting pattern of the basic form and the contacting form we must take into account can be restricted within fixed region, 4therefore phoneme segmentation not influenced by characters form and any other contact in a single character is performed as matching this local graph pattern with base patterns searched ahead. This experiments with 540 characters have been conducted. From the result of this experiment, it is shown that phoneme segmentation is independent of characters form and other contact in a single character to obtain a correct segmentation rate of 95%, manages it efficiently to reduce the time spent in lock operation when the lock.

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Study on the Performance Improvement of Roof Fan Used for Local Exhaust System Installed in Apartment (공동주택의 국소배기용 루프팬 성능개선에 관한 연구)

  • Kwon, Yong-Il;Jeong, Yeol-Wha;Ahn, Jung-Hun
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.24 no.2
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    • pp.136-141
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    • 2012
  • Performance improvement of local exhaust system used in toilet and cooking place are main concern in a field of ventilation. In Korea, There are many high riser residential apartments in recent years. These buildings were not viewed as being major contributors to exhaust pollutants producted in indoor. It was because many engineers thought that exhaust in high riser building depends on stack effect. This study investigates on the performance improvement of terminal device, roof fan, of vertical spiral duct used in high riser residential apartments. This paper focuses mainly on the effect of accessories, number or shape of blades, composed of roof fan with function of exhaust air volume of toilet and cooking place. Roof fan with 10 blades is observed at optimum exhaust performance in this study.

Body Distribution of $^{125}I-rhEGF$ Across Normal and Damaged Rat Skins (정상 및 손상된 흰쥐 피부에 국소 적용된 $^{125}I-rhEGF$의 체내 이행)

  • Lee, Jeong-Uk;Chung, Suk-Jae;Lee, Min-Hwa;Shim, Chang-Koo
    • YAKHAK HOEJI
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    • v.41 no.6
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    • pp.730-736
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    • 1997
  • Distribution of radioactivity in the skin tissues, subcutaneous tissues, blood and body organs was examined following topical application of $^{125}I-rhEGF$(0.4 ${\mu}Ci$), in the form of a Pluronic F-127 gel, on the normal and damaged (burned and stripped) skins of SD male rats. The radioactivity in the skin tissues and subcutaneous tissues was 3-5 times higher for the damaged skins than for the normal skin. But pretreatment of the skin with rhEGF (1${\mu}g$)) twice at 24 hr dose intervals affected the distribution of the radioactivity yielding the order of burned skin> stripped skin=normal skin. The decrease for the stripped skin by the pretreatment might be related either to the pathophysiological change of the skin or to the down regulation of the EGF receptor. Liver showed the highest radioactivity in amount following single and multiple administration of the drug to the normal and damaged skins. But,in concentration, the kidney and stomach showed higher value than the liver which is consistent with that kidney is a major eliminating organ of EGF and that EGF exerts its pharmacological effect specifically for the stomach.

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A Case of the Laryngeal Papilloma Observed for the Past 13 Years (13년간 경과를 관찰한 후두유두종의 1예)

  • 이양선;박윤이;이인환
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1983.05a
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    • pp.5.2-5
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    • 1983
  • It is well known that laryngeal papilloma is histopathological benign, but clinically one of the most troublesome disease in otolaryngologic department, usually seen in child age. Since Cleesmann reported papilloma of the vocal cord, 1817 first, the etiology had not been known exactly. The symptoms in children are dyspnea, dysphonia due to recurrence, and papilloma in adult can change into neoplasm. The papilloma is thought as real neoplastic lesion and there is not effective treatment, using now repeated removal and combined therapy. This report is based on the typical findings and progress of one case of laryngeal papilloma observed for the past 13 years with repeated removal and topical application of 5-FU at our department. Authors have experienced this subject is interesting that the change of the tumor region during the course than to any new therapeutic methods employed, and so report with some reviews of the literatures.

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Potential of Fuel Stratification for Reducing Pressure Rise Rate in HCCI Engines (HCCI 기관에 있어서의 층상 흡기를 통한 압력 상승률 저감에 대한 연구)

  • Lim, Ock-Taeck
    • Journal of the Korean Institute of Gas
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    • v.14 no.6
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    • pp.7-14
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    • 2010
  • This study investigated the effect on reducing the pressure rise rate(PRR) in HCCI Engine by the variation of mixing ratio in the pre-mixture of DME and n-Butane that has different auto-ignition characteristics. In addition to measure of gas pressure in the engine cylinder, chemiluminescence image using the optical accessible engine and numerical analysis with multi-zones model were used to assess the combustion at each local area in the combustion chamber. The maximum PRR changes depending on mixing condition of DME and n-Butane. When DME is stratified and n-Butane is distributed uniformly, maximum PRR becomes lowest which is about 0.25MPa/ms and it corresponds to 5deg. retarding of CA50.

심플렉틱 다양체의 불변량

  • 조용승
    • Communications of the Korean Mathematical Society
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    • v.15 no.3
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    • pp.391-434
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    • 2000
  • 심플렉틱 구조는 국소적으로는 모두 같기 때문에 심플렉틱 다양체 연구는 대역적으로 연구해야한다. 그로모브가 복소해석학적 곡선을 원소를 하는 모률라이 공간의 연구가 심플렉틱 다양체를 연구하는 물고를 텃다. 특이점이 없는 복소곡선의 개수를 세는 그로모브 불변량은 도넬슨의 비선형 게이지 이론의 간략화라 할 수 있는 아벨리안게이지 이론에서 사이버그-위튼 불변량과 같음을 타우브스가 발견하였다. 또한 사이버그-위튼 불변량은 심플렉틱 다양체의 불변량으로 심플렉틱 구조연구에 큰 이바지하고 있다. 그로모브의 모듈라이 공간의 컴펙트하는 과정에서 자연스럽게 마크점과 특이점을 갖는 곡선의 그로모브-위튼 모듈라이 공간이 켐펙트가 되고 여기소 그로모브-위튼 불변량이 얻어진다. 이 그로모브-위튼 불변량은 대수기하와 이론 물리학의 끈이론에서 찾는 대수곡선의 개수를 나타내고, 코호몰로지의 컵곱의 일반화라 할 수 있는 퀸텀곱을 유도하고, 그로모브-위튼 포텐셜함수의 계수를 결정한다. 퀸텀곱의 결합법칙은 포텐셜함수의 WDVV-방정식과 동치를 나타나며 이는 프로베니우스 구조가 평탄함을 나타낸다. 그로모브-위튼 불변량은 앞으로 활발히 연구되고 수학에 광범하게 이바지 할 것이다.

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Pain control using the Point-Inject Technique in dental local anesthesia (Point Inject Technique을 이용한 치과 국소마취의 통증 조절 및 진료 효율의 극대화)

  • Lee, Jae-youn;Choe, Sunga
    • Journal of Korean Academy of Dental Administration
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    • v.9 no.1
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    • pp.32-37
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    • 2021
  • Many approaches to local anesthesia have been studied in dentistry. In this study, we introduce a new local anesthetic method, "Point-Inject Technique (PIT)", and compare it with traditional injection techniques. The PIT method utilizes both the vasoconstrictive and antinociceptive properties of local anesthetics as well as the application of controlled pressure during injection, reducing the time to complete anesthesia. Fifty patients were selected as the experimental group who were anesthetized using PIT, and the other 50 patients were selected as the control group using the direct injection method with a carpool syringe. The PIT group received 0.25 cartridges of 2% lidocaine with 1:100,000 epinephrine. The control group received 1.5~2 cartridges of 2% lidocaine with 1:100,000 epinephrine. Both groups were asked to mark the intensity of the pain caused by anesthesia using the Numeric Pain Rating Scale. The average time to recover from anesthesia was 40 minutes in the experimental group and 90 minutes in the control group. Additionally, 96% of the experimental group reported feeling no pain, while 78% of the control group reported having some form of pain during injection. The PIT method reduced both the reported pain scores of patients as well as time to recover from local anesthesia than the widely-used syringe injection method.

Estimation of Internal Motion for Quantitative Improvement of Lung Tumor in Small Animal (소동물 폐종양의 정량적 개선을 위한 내부 움직임 평가)

  • Yu, Jung-Woo;Woo, Sang-Keun;Lee, Yong-Jin;Kim, Kyeong-Min;Kim, Jin-Su;Lee, Kyo-Chul;Park, Sang-Jun;Yu, Ran-Ji;Kang, Joo-Hyun;Ji, Young-Hoon;Chung, Yong-Hyun;Kim, Byung-Il;Lim, Sang-Moo
    • Progress in Medical Physics
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    • v.22 no.3
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    • pp.140-147
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    • 2011
  • The purpose of this study was to estimate internal motion using molecular sieve for quantitative improvement of lung tumor and to localize lung tumor in the small animal PET image by evaluated data. Internal motion has been demonstrated in small animal lung region by molecular sieve contained radioactive substance. Molecular sieve for internal lung motion target was contained approximately 37 kBq Cu-64. The small animal PET images were obtained from Siemens Inveon scanner using external trigger system (BioVet). SD-Rat PET images were obtained at 60 min post injection of FDG 37 MBq/0.2 mL via tail vein for 20 min. Each line of response in the list-mode data was converted to sinogram gated frames (2~16 bin) by trigger signal obtained from BioVet. The sinogram data was reconstructed using OSEM 2D with 4 iterations. PET images were evaluated with count, SNR, FWHM from ROI drawn in the target region for quantitative tumor analysis. The size of molecular sieve motion target was $1.59{\times}2.50mm$. The reference motion target FWHM of vertical and horizontal was 2.91 mm and 1.43 mm, respectively. The vertical FWHM of static, 4 bin and 8 bin was 3.90 mm, 3.74 mm, and 3.16 mm, respectively. The horizontal FWHM of static, 4 bin and 8 bin was 2.21 mm, 2.06 mm, and 1.60 mm, respectively. Count of static, 4 bin, 8 bin, 12 bin and 16 bin was 4.10, 4.83, 5.59, 5.38, and 5.31, respectively. The SNR of static, 4 bin, 8 bin, 12 bin and 16 bin was 4.18, 4.05, 4.22, 3.89, and 3.58, respectively. The FWHM were improved in accordance with gate number increase. The count and SNR were not proportionately improve with gate number, but shown the highest value in specific bin number. We measured the optimal gate number what minimize the SNR loss and gain improved count when imaging lung tumor in small animal. The internal motion estimation provide localized tumor image and will be a useful method for organ motion prediction modeling without external motion monitoring system.