• 한국방재학회:학술대회논문집
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• 2011.02a
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• pp.190-190
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• 2011

사회 다변화 및 급속한 경제성장과 도시밀집화로 인하여, 화재의 발생으로 인하여 막대한 인명피해 및 대규모의 재산상의 피해가 지속적으로 발생하고 있다. 이러한 화재의 피해를 예측하기 위해서는 실제 규모의 화재실험이 매우 유용하지만, 막대한 비용과 현실적 제약조건으로 인하여 실제 실험에는 많은 어려움이 따른다. 따라서 막대한 예산이 소요되는 실제규모의 화재실험의 대체방법으로 실제를 모사하는 축소모형 화재모의실험 및 컴퓨터를 이용한 화재 시뮬레이션 기법이 널리 이용되고 있다. 본 논문에서는 범용 컴퓨터를 이용한 화재 시뮬레이션 기법(CFAST)을 이용하여 수직 공간 구성을 가지는 단독주택의 화재 성상을 검토하였다. 시뮬레이션 모델로는 단독주택을 대상건물로 하여 2층으로 수직 공간을 가지는 단독주택 건물에 대한 모의 화재 시뮬레이션을 수행 하였다. 화재 시뮬레이션 결과는 각 구획실별 온도, 일산화탄소량, 공기 중 산소량 등을 도출하여 기존 이론에 의한 화재성장 그래프와 시뮬레이션 데이터를 비교하여 정확도를 검토하였다. 본 논문에서는 두가지의 시나리오를 작성하여 화재 시뮬레이션 프로그램의 결과 값을 분석하였다. (1) 시나리오 1 : 화재시뮬레이션 대상건물 1층 거실(2번방)에서 스프링클러 미 설치시 화재가 발생한 경우를 가정하여 수평방향인 3번방과 수직방향인 7번방의 화재 확산 피해정도를 살펴보고, 화재 그래프의 이론값과 실험값의 차이를 비교하여 그 정합성을 검토하였다. 발화물질은 Curtain, TV set, Sofa, Table으로 하며 시간은 60초 간격으로 총 3600초(1시간)를 분석 하였고, 발화지점의 온도, 일산화탄소, 공기중 산소 농도를 분석하였다. (2) 시나리오 2 : 시나리오 1과 동일한 화재발현 조건으로 스프링클러가 설치되어 있을 때 화재 발생 했을 경우, 수평방향인 3번방과 수직방향인 7번방의 화재 확산 피해를 시나리오 1과 비교 검토 하였다. 기존 이론에 의한 화재 성장 그래프와 이번 시뮬레이션 결과값을 토대로 만든 그래프 형태를 비교해보면 두 그래프의 형태가 비슷한 형태를 나타내어 Flash Over 현상과 Back Draft 현상이 이론값과 같은 경향을 나타내고 있음을 확인 할 수 있었다. 따라서, 본 논문에서 수행한 화재 시뮬레이션 기법으로 건축물의 실제 화재시의 피해정도를 예측하는 데 유용하게 활용될 것으로 판단된다.

• Journal of the Korean association of regional geographers
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• v.14 no.2
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• pp.114-125
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• 2008

Colored dissolved organic matter(CDOM) is an important component of ocean color that can be used as an invaluable tool in water quality and ocean color studies. With the largest source of coastal CDOM appearing to be from freshwater discharge into the ocean, coastal predictive models will do much to refine our knowledge about major processes that control CDOM distributions in coastal waters and provide a better insight into the global carbon cycle. This study aims at developing a GIS-based watershed-scale predictive model of CDOM distributions in Neponset river watersheds that can be used to appraise our understanding of CDOM sources and distributions in coastal waters and predict the response of CDOM concentration to changes in land use patterns. Weighting factors are developed for CDOM freshwater sources after extensive groundtruthing from various landuse types in the watershed. This model makes use of a publicly available DEM(Digital elevation model) as the base data for analysis. Stream networks, discharge, and land use data are used from public repositories while sub- watershed delineation, pour-points, and land use parcels are generated using Spatial Analysis of ArcGIS 9.2 to estimate the CDOM loading from various sources to the lower tributaries of rivers. The Neponset Watershed in eastern Massachusetts is selected as the site for development of the model.

• The Korean Journal of Nuclear Medicine
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• v.37 no.5
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• pp.288-300
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• 2003

Purpose: To obtain regional blood flow and tissue-blood partition coefficient with time-activity curves from ${H_2}^{15}O$ PET, fitting of some parameters in the Kety model is conventionally accomplished by nonlinear least squares (NLS) analysis. However, NLS requires considerable compuation time then is impractical for pixel-by-pixel analysis to generate parametric images of these parameters. In this study, we investigated several fast parameter estimation methods for the parametric image generation and compared their statistical reliability and computational efficiency. Materials and Methods: These methods included linear least squres (LLS), linear weighted least squares (LWLS), linear generalized least squares (GLS), linear generalized weighted least squares (GWLS), weighted Integration (WI), and model-based clustering method (CAKS). ${H_2}^{15}O$ dynamic brain PET with Poisson noise component was simulated using numerical Zubal brain phantom. Error and bias in the estimation of rCBF and partition coefficient, and computation time in various noise environments was estimated and compared. In audition, parametric images from ${H_2}^{15}O$ dynamic brain PET data peformed on 16 healthy volunteers under various physiological conditions was compared to examine the utility of these methods for real human data. Results: These fast algorithms produced parametric images with similar image qualify and statistical reliability. When CAKS and LLS methods were used combinedly, computation time was significantly reduced and less than 30 seconds for $128{\times}128{\times}46$ images on Pentium III processor. Conclusion: Parametric images of rCBF and partition coefficient with good statistical properties can be generated with short computation time which is acceptable in clinical situation.

• The Journal of Korean Society for Radiation Therapy
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• v.34
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• pp.43-50
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• 2022

Objective: The purpose of this study is to choose a treatment plan and equipment to maximize tangential irradiation to protect the normal brain tissues as much as possible during total scalp irradiation. Subjects and Methods: After zoning the total scalp of a phantom and selecting a target area for treatment, the study made a Helical TomoTherapy(HT) plan, a Helical TomoTherapy with a Complete Block(HTCB) plan, and a Volumetric Modulated Arc Therapy(VMAT) plan. All of these plans made sure that the volume of a treatment plan with 95% of a prescription dose(40 Gy) would not exceed 95% of the entire volume and that Dmax would not be more than 110% of the prescription dose. The therapy plans compared doses among organs at risk of damage including the brain. Doses in the brain tissues were assessed based on the volumetric criteria for normal tissues in Emami et al. Results: HT, HTCB, and VMAT had a dose of 21.68 Gy, 13.75 Gy, and 20.89 Gy, respectively, in brain tissues at D_33%, a dose of 7.06 Gy, 3.21 Gy, and 7.84 Gy, respectively, at D_67%, and a dose of 3.14 Gy, 1.75 Gy, and 3.84 Gy, respectively, at D_100%. They recorded a Dmean of 16.64 Gy, 11.78 Gy, and 16.64 Gy, respectively. These results show that the overall dose was low in the HTCB plan. When the volume of a low dose was calculated based on 5 Gy, they recorded 87%, 49%, and 96%, respectively, in V_5Gy. In addition, the maximum dose in the remaining organ(brain stem, hippocampus, and both lenses) except for the optic pathway was the lowest in HTCB Conclusion: The findings demonstrate that TomoTherapy with a complete block minimized a dose in organs at risk of damage including the brain and hippocampus on both sides and accordingly reduced the probability of side effects such as radiation-induced brain injuries and a resulting decrease in neurocognitive functions. In addition to total scalp irradiation, if additional studies on ring targets treated in various areas are conducted to establish the benefits of tangential irradiation, it is believed that TomoTherapy using Complete Block can be used to maximize tangential irradiation in treatment planning.

• The Korean Journal of Nuclear Medicine
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• v.31 no.1
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• pp.19-29
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• 1997

Recently, [I-123]IPT SPECT has been used for early diagnosis of Parkinson's patients(PP) by imaging dopamine transporters. The dynamic time activity curves in basal ganglia(BG) and occipital cortex(OCC) without blood samples were obtained for 2 hours. These data were then used to measure dopamine transporters by operationally defined ratio methods of (BG-OCC)/OCC at 2 hrs, binding potential $R_v=k_3/k_4$ using graphic method or $R_A$= (ABBG-ABOCC)/ABOCC for 2 hrs, where ABBG represents accumulated binding activity in basal ganglia(${\int}^{120min}_0$ BG(t)dt) and ABOCC represents accumulated binding activity in occipital cortex(${\int}^{120min}_0$ OCC(t)dt). The purpose of this study was to examine the IPT pharmacokinetics and investigate the usefulness of simplified methods of (BG-OCC)/OCC, $R_A$, and $R_v$ which are often assumed that these values reflect the true values of $k_3/k_4$. The rate constants $K_1,\;k_2\;k_3$ and $k_4$ to be used for simulations were derived using [I-123]IPT SPECT and aterialized blood data with a standard three compartmental model. The sensitivities and time activity curves in BG and OCC were computed by changing $K_l$ and $k_3$(only BG) for every 5min over 2 hours. The values (BG-OCC)/OCC, $R_A$, and $R_v$ were then computed from the time activity curves and the linear regression analysis was used to measure the accuracies of these methods. The late constants $K_l,\;k_2\;k_3\;k_4$ at BG and OCC were $1.26{\pm}5.41%,\;0.044{\pm}19.58%,\;0.031{\pm}24.36%,\;0.008{\pm}22.78%$ and $1.36{\pm}4.76%,\;0.170{\pm}6.89%,\;0.007{\pm}23.89%,\;0.007{\pm}45.09%$, respectively. The Sensitivities for ((${\Delta}S/S$)/(${\Delta}k_3/k_3$)) and ((${\Delta}S/S$)/(${\Delta}K_l/K_l$)) at 30min and 120min were measured as (0.19, 0.50) and (0.61, 0,23), respectively. The correlation coefficients and slopes of ((BG-OCC)/OCC, $R_A$, and $R_v$) with $k_3/k_4$ were (0.98, 1.00, 0.99) and (1.76, 0.47, 1.25), respectively. These simulation results indicate that a late [I-123]IPT SPECT image may represent the distribution of the dopamine transporters. Good correlations were shown between (3G-OCC)/OCC, $R_A$ or $R_v$ and true $k_3/k_4$, although the slopes between them were not unity. Pharmacokinetic computer simulations may be a very useful technique in studying dopamine transporter systems.