• Journal of the Korea Computer Graphics Society
• /
• v.6 no.1
• /
• pp.19-27
• /
• 2000

This paper proposes a non-self-intersecting multiresolution deformable model to extract and reconstruct three-dimensional boundaries of objects from volumetric data. Deformable models offer an attractive method for extracting and reconstructing the boundary surfaces. However, convensional deformable models have three limitations- sensitivity to model initialization, difficulties in dealing with severe object concavities, and model self-intersections. We address the initialization problem by multiresolution model representation, which progressively refines the deformable model based on multiresolution volumetric data in order to extract the boundaries of the objects in a coarse-to-fine fashion. The concavity problem is addressed by mesh size regularization, which matches its size to the unit voxel of the volumetric data. We solve the model self-intersection problem by including a non-self-intersecting force among the customary internal and external forces in the physics-based formulation. This paper presents results of applying our new deformable model to extracting a sphere surface with concavities from a computer-generated volume data and a brain cortical surface from a MR volume data.

• Journal of Korea Water Resources Association
• /
• v.31 no.4
• /
• pp.363-373
• /
• 1998

In this study, random flow field in a nonstationary porous formation is characterized through cross covariances of the velocity with the log conductivity and the head. The hydraulic head and the velocity in saturated aquifers are found through stochastic analysis of a steady, two-dimensional flow field without recharge. Expression for these cross covariances are obtained in quasi-analytic forms all in terms of the parameters which characterize the nonstationary conductivity field and the average head gradient. The cross covariances with a Gaussian correlation function for the log conductivity are presented for two particular cases where the trend is either parallel or perpendicular to the mean head gradient and for separation distances along and across the mean flow direction. The results may be of particular importance in transport predictions and conditioning on field measurements when the log conductivity field is suspected to be nonstationary and also serve as a benchmark for testing nonstationary numerical codes. Keywords : cross covariance, nonstationary conductivity field, saturated aquifer, stochastic analysis.

• Journal of Life Science
• /
• v.22 no.10
• /
• pp.1316-1323
• /
• 2012

The present study was conducted to investigate whether myoblasts can be transdifferentiated into adipocytes by ectopic expression of adipogenic transcription factors, including peroxisome proliferator-activated receptor-${\gamma}$ ($PPAR{\gamma}$), CCAAT/enhancer-binding protein-${\alpha}$ (C/$EBP{\alpha}$), sterol regulatory element binding protein-1c (SREBP1c), and Krueppel-like factor 5 (KLF5), in primary bovine satellite cells. Transcription factors were transiently transfected into primary bovine myoblasts, and the cells were cultured with adipogenic differentiation medium for 2 days and then cultured on growth medium for an additional 8 days. Ectopic expression of $PPAR{\gamma}$ or C/$EBP{\alpha}$ alone was insufficient to induce adipogenesis in myoblasts. However, overexpression of both $PPAR{\gamma}$ and C/$EBP{\alpha}$ in myoblasts was able to induce adipogenic transdifferentiation as indicated by the appearance of mature adipocytes, the induction of adipogenic gene expressions, and the suppression of myogenic gene expressions. In addition, KLF5 and $PPAR{\gamma}$ co-transfected bovine myoblasts were converted to adipocytes but not in cells transfected with only KLF5 expression vector. Overexpression of SREBP1c alone was sufficient to induce transdifferentiation from myoblasts into adipocytes. These results demonstrate that primary bovine satellite cells can be transdifferentiated into adipocytes either by single ectopic expression or combined expression of adipogenic transcription factors in a culture system.

• The Transactions of the Korea Information Processing Society
• /
• v.5 no.12
• /
• pp.3109-3116
• /
• 1998

본 논문에서는 대규모 병렬컴퓨터의 구현에 적합한 위상구조인 교차메쉬구조에서, 균등한 메시지분포를 갖고 메시지의 경쟁이 있는 실제적 상황에서 상호접속망내의 메시지의 경로를 선정하기 위한 방법들을 제안하고, 이의 성능을 검증하기 위해 우회 경로설정 알고리즘을 이용하여 시뮬레이션을 하였다. 교차메쉬의 특성상 최적경로의 수가 다른 구조들에 비해 다양하다는 특징을 이용하여 최적경로의 수를 우선순위에 반영한 우회조건 및 대각방향의 링크를 효율적으로 활용하기 위한 링크선정방법에 따를 교차메쉬의 최대지연(maximum delay), 평균지연(average delay) 및 메시지처리율(throughput)을 구하고 이를 비교 고찰하였다. 메시지 전송시 최적인 경로상의 링크에 경합이 생길 경우 최적 경로의 수가 적은 메시지가 높은 우선순위를 가지며 만약 같은 조건이라면 우회한 횟수가 많은 메시지가 높은 우선순위를 갖는 우회조건 LD를 사용하며 이 우선순위에 따라 경로를 선정할 차례가 된 메시지가 선택할 수 있는 최적경로의 수가 많을 경우 대각방향의 링크로 우선적으로 전송할 경우, 오래된 메시지가 높은 우선순위를 갖는 우회조건 A에 의한 방법에 비해 최대지연, 평균지연 및 메시지처리율에 있어서 각각 이상값에 대한 개선목표치의 약58%, 70% 및 31%의 성능개선이 있었다.

• The Korean Journal of Applied Statistics
• /
• v.14 no.2
• /
• pp.345-355
• /
• 2001

동일한 유효성분을 가지면서 용량 혹은 형식 만이 다른 제제의 개발이 증가되고 이에 따른 두 제제 이상의 생물학적 동등성시험의 필요성이 제기되었다. 이에 이용주 등(1998)은 온단세트론 제제에 대한 생물학적 동등시험에서 3$\times$3 교차설계법을 적용하였다. 그러나 3$\times$3 교차설계법에서 각 순서에 피험자의 수가 다르거나 실험중에 결락(dropout)되는 피험자가 발생하는 경우에는 일반적인 통계적 방법은 적용할 수 없었다. 본 연구에서는 이러한 경우에 제제효과의 추론에 대한 통계적 방법과 생물학적 동등성 시험 방법을 제안하고 모의실험을 통하여 생물학적 동등성평가의 정도를 측정하였다.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.11 no.2
• /
• pp.151-157
• /
• 2000

The ITU-R model for cross-polarization, which is accurate enough in real rainfall environments, is proposed in this paper. By comparing this with measurement data and the ITU-R model, we have also derived a prediction model for rain cross-polarization applicable upto millimeter wave band.

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.7 no.4
• /
• pp.285-294
• /
• 2005

The behaviors of the ground in crossed zone and the existing upper tunnel in shallow cover due to the excavation of new lower tunnel crossed to that was studied. Model test was performed in the large scale test pit, the size was '$4.0m(width){\times}3.8m(height){\times}4.1m(length)$'. Test ground was constructed uniformly by sand in middle density and test with the crossed angle of $56^{\circ}$ (obliquely) were performed. The numerical analysis was performed on equal condition with model test. Results of the study by model test and numerical analysis show that earth pressure and settlement of the ground in crossed zone were redistributed due to the longitudinal arching effect by the excavation of lower tunnel. Model test shows that upper tunnel blocks stress flow due to the longitudinal arching effect by excavation of lower tunnel.

• Communications of Mathematical Education
• /
• v.37 no.2
• /
• pp.199-212
• /
• 2023

The purpose of this study is to find out whether there is a difference in achievement between blocked practice and interleaved practice according to the difference in domain and type of learning content in mathematics subject, and through this result, it is to confirm whether the effect of interleaved practice in mathematics learning is due to the 'Discriminative-contrast Hypothesis' or the 'Distributed-practice Hypothesis'. Although interleaved practice is more effective than blocked practice, previous studies have not shown consistent results regarding the cause. Therefore, in this study, 103 first-year middle school students were randomly assigned to blocked practice, interleaved practice, remote blocked practice, and remote interleaved practice groups had learning activities over 4 times. The results reveals that the effect of interleaved practice appeared in similar types in the same domain, but the effect of interleaved practice did not appear in different types in different domain. In addition, through this result, it was confirmed that the effect of interleaved practice was due to the 'Discriminative-contrast hypothesis' rather than the 'Distributed-practice hypothesis'. Further research topics were suggested after the issues on the research method and the findings were discussed.

• Proceedings of the KIPE Conference
• /
• 2016.11a
• /
• pp.101-102
• /
• 2016

영구자석 동기전동기(PMSM)의 효율적인 구동을 위해 전동기의 제정수를 실시간으로 정확하게 추정하는 것이 매우 중요하다. 대부분의 전동기 제정수 추정 기법은 전동기의 교차 결합 현상(Cross coupling effect)을 고려하지 않은 전동기 모델을 이용한다. 본 논문에서는 영구자석 동기전동기에서 기존의 제정수 추정 기법을 적용할 경우 교차 결합 현상에 의해 발생하는 제정수의 추정 오차를 수학적으로 분석하고 이를 시뮬레이션을 통해 검증하였다.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.20 no.2
• /
• pp.234-242
• /
• 2010

In this paper, we deal with the visualization of graphs, which are one of the most important data structures. As the size of a graph increases, it becomes more difficult to check the graph visually because of the increase of edge intersections. We propose a new method of overcoming such problem. Most of previous studies considered only the minimization of edge intersections, but we additionally pursue to preserve distances between vertices. We present a novel genetic algorithm using an evaluation function based on a weighted sum of two objectives. Our experiments could show effective visualization results.