• Laboratory Medicine Online
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• v.1 no.1
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• pp.26-34
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• 2011

Background: Laboratory diagnosis of new influenza A (H1N1) is crucial for managing patients and establishing control and prevention measures. We compared the diagnostic accuracies of the real time RT-PCR (rRT-PCR) test recommended for the confirmation of the new flu and the viral culture method used conventionally for viral disease with that of the rapid antigen test (RAT). Methods: We performed RAT, R-mix culture, and real-time PCR by using 861 respiratory samples collected from December 2009 to January 2010 and evaluated the abilities of these methods to detect new influenza A. The relationship among the positive rates of RAT, grades of culture, and the cycle threshold (Ct) values of rRT-PCR was also evaluated. Results: Of the 861 patients, 308 (35.8%) were diagnosed with new influenza A. The sensitivities, specificities, positive predictive values, and negative predictive values of the tests were respectively as follows: 59.7%, 99.5%, 98.4%, and 81.6% for RAT; 93.2%, 100%, 100%, and 96.3% for R-mix culture; and 95.8%, 100%, 100%, and 97.7% for rRT-PCR. Samples with weak positive grade in culture and those with Ct values of 30-37 in rRT-PCR showed positivities as low as 25.3% and 2.3% in RAT, respectively. The hospitalization rate and death rate of the confirmed patients were 3.2% and 0.3%, respectively, and gastrointestinal symptoms were observed in 7.2% of the patients. Conclusions: R-mix culture and rRT-PCR tests showed excellent reliability in the diagnosis of new influenza A and could be very useful, especially for samples with low viral load.

• The Journal of Korean Academy of Prosthodontics
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• v.61 no.2
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• pp.113-124
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• 2023

Purpose. The purpose of this study is to help increase the success rate by analyzing the types and characteristics of implant prosthesis and the survival rate. Materials and methods. Among implants placed between 2011 and 2020 at Sanbon Dental Hospital, College of Dentistry, Wonkwang University, a case restored by a prosthetic surgeon was investigated for the characteristics and correlation of failure. The causes of failure were classified as failure of osseointegration, peri-implantitis, fixture fracture, abutment fracture, screw fracture, screw loosening, prosthesis fracture, and loss of prosthesis retention. Prosthetic method, cantilever presence, placement location, etc. were analyzed for their correlation with implant failure. Results analysis was derived through Chi-square test and Kaplan-Meier survival analysis using SPSS ver 25.0 (IBM, Chicago, IL, USA). Results. A total of 2587 implants were placed, of which 1141 implants were restored with Single Crown and 1446 implants with Fixed Partial Denture, and the cumulative survival rate was 88.1%. The success rate of SC was 86.2% (984) and the success rate of FPD was 89.6% (1295), showing statistically significant differences, among which factors that had significant differences were abutment fracture, screw fracture, and screw loosening (P < .05). Conclusion. As a result of the 10-year follow-up, more failures occurred due to biomechanical factors than biological factors. Further studies on the success of implants will be needed in the future.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.14 no.2
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• pp.97-101
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• 2018

Lesch-Nyhan syndrome is a rare X-linked recessive genetic disorder. During purine metabolism, the hypoxanthine guanine phosphribosyl transferase (HGPRT) enzyme is deficient causing phosphoribosyl transferase to accumulate and resulting in excessive uric acid. Clinical symptoms include hypercalcemia, choreoathetosis, spasticity, mental retardation, and self-injury to lips, tongue or fingers. This results not only in pain caused by the self-injury but also secondary infection of the wound site and the esthetic damage of the soft tissue defect. Dental treatments include conservative methods using intraoral appliances such as soft mouthguards, fixed lip bumpers, and occlusal guards, and invasive methods such as extraction of all teeth or forming an artificial anterior open bite. We report two cases of Lesch-Nyhan syndrome patients with self-mutilation behavior; one was treated with a preservative method using a soft mouthguard, and the other was treated with extraction of all teeth.

• Proceedings of the Korea Information Processing Society Conference
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• 2008.11a
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• pp.676-678
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• 2008

임상 의무기록에 나타나는 많은 두문자어들은 기계적인 처리과정에서 의무기록의 모호성을 크게 증가시키기 때문에, 정보추출이나 텍스트 마이닝을 하기 전에 전처리 과정으로 의무기록이 정규화 되어야 한다. 본 연구에서는 임상 의무기록 중 하나인 퇴원요약지에 사용된 약어와 두문자어들의 모호성을 제거하기 위한 정규화 시스템을 설계하고 구현했다. 정규화를 위해 문맥정보를 이용하여 의무기록의 종류와 기록내 위치정보를 파악하였고 이를 이용하여 약어와 두문자어의 의미를 학습하고 분류하였다. 본 연구에서 구현한 정규화 시스템은 실험에서 6가지 두문자어들이 가지는 16가지 의미들에 대해 94.7%의 정확률을 얻었다.

• Journal of the Korean Institute of Educational Facilities
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• v.19 no.1
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• pp.13-24
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• 2012

Recently, many middle and high schools are remodeling the buildings and facilities based on departmental system. This study, through analyzing on 10 remodeling cases of high school, is showing the variation before and after remodeling, space organization types, and the types of school management. This also gives us the information on the number of classrooms and teachers' rooms for each subject, the area and number of home base, and the current state of all these facilities. Furthermore, this study is comparing and analyzing the rate of use of specialized classrooms to the type of management. Through this analysis, we reach the following conclusions. l. However all the cases remodeled their buildings to implement departmental system, the methods of space composition, the numbers of the classrooms, and the status of home base are in various forms. 2. Taken as a whole, there are only few spaces used by departmental system. 3. The spaces for practical subjects such as Science and Art are inadequate than the ones for major subjects such as Languages and Mathematics. 4. A system to assign a room for a teacher records the lowest space usage rate. 5. The area of home base per one student is only $0.48m^2$, and even the area is mostly filled with lockers. The present condition of the 10 high schools which we surveyed shortly after remodeled shows that departmental system is not firmly settled down yet.

• Journal of Dental Rehabilitation and Applied Science
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• v.40 no.3
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• pp.125-134
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• 2024

Purpose: The aim of this study was to determine which scan range would provide the most accurate bite registration when performing a bite scan after scanning an upper and lower arch using an intraoral scanner. Materials and Methods: The occlusal contact points were recorded using articulating paper for 30 adults, and the results of various ranges of buccal bite scan were compared based on this. Buccal bite scan of 5 ranges (1st premolar to 2nd premolar, 1st premolar to 1st molar, 1st premolar to 2nd molar, 2nd premolar to 1st molar, and canines to another side canine of the maxillary teeth) was performed, and then the buccal bite scan file was used in a CAD program to confirm the occlusal area in the scan file through data editing and alignment, leaving the buccal area of the teeth. Afterwards, the degree of agreement between the occlusal contact points obtained from the articulating paper and the occlusal area obtained from the scan file was compared, and statistical analysis was performed using the homoscedastic T-test (α = 0.05). Results: The alignment success and alignment failure rates among each group were 77.23% and 40.85% in canine to another side canine, 68.23% and 28.89% in bilateral first premolar to second premolar, 63.76% and 29.97% in bilateral first premolar to first molar, 61.31% and 32.04% in bilateral first premolar to second molar, 67.55% and 27.46% in second premolar to first molar. The results of the anterior scan of both canines showed higher alignment success and failure rates compared to the scan results of all maxillary posterior teeth. In the alignment success rate, statistical significance was not found depending on the scan range of the posterior teeth, but in comparing the results of the posterior teeth and both canines, statistical significance was observed except for the scan results of the second premolar to the first molar. There was no statistical significance in the alignment failure rate depending on the scan range of the posterior teeth, and statistical significance was observed in the results of the posterior teeth and both canines. Conclusion: When taking a buccal bite scan, in the case of scanning the anterior teeth, more occlusal area appear than when scanning the posterior teeth, and in the case of scanning the posterior teeth, there is no significant difference in the bite registration depending on the scan range.

• Sleep Medicine and Psychophysiology
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• v.26 no.1
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• pp.16-22
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• 2019

Objectives: The objective of this study was to investigate the correlation between insufficient sleep and visuospatial memory in adolescents using a computerized neurocognitive function test. Methods: A total of 103 high school students (26 males and 77 females; mean age $17.11{\pm}8.50years$) without a serious psychiatric problem was recruited. All subjects were requested to complete a self-report questionnaire about weekday total sleep time and weekend total sleep time. The epworth sleepiness scale (ESS) and the beck depression inventory (BDI) were administered to measure daytime sleepiness and symptoms of depression. Seven subsets of the Cambridge Neuropsychological test automated battery were examined to assess visuospatial memory. Results: After controlling for age, sex, ESS, and BDI, longer weekend total sleep time was correlated with poor performance on delayed matching to sample (r = -0.312, p = 0.002) and immediate recall on pattern recognition memory (r = -0.225, p = 0.025). Increased weekend catch-up sleep time was correlated with poor performance of delayed matching to sample (r = -0.236, p = 0.018), immediate recall on pattern recognition memory (r = -0.220, p = 0.029), and delayed recall on pattern recognition memory (r = -0.211, p = 0.036) after controlling for age, sex, ESS, and BDI. Conclusion: This study showed that increased weekend catch-up sleep time reflecting insufficient weekday sleep were associated with poor performance in delayed recall tasks of visual memory. This finding suggests that insufficient sleep during adolescence might produce a decline of visuospatial memory.

• The Journal of the Acoustical Society of Korea
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• v.38 no.6
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• pp.651-660
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• 2019

The present study aims to find out the necessary speech sound level which can satisfy with the speech intelligibility in a noisy classroom environments. For this, auralized materials were made to undertake listening tests with 27 people. Speech intelligibility tests were carried out using both Consonant-Vowel-Consonant (CVC) and Phonetically Balanced Words (PBW) methods. Signal to noise ratio was changed by 5 dB for each test. As a result, it was found that speech intelligibilities are increasing with larger Signal to Noise Ratio (SNR). It was also found that there is a lot of difference of speech intelligibilities by SNR for syllables (CVC) with the Reverberation Time (RT) of 1.5 s. However, any significant difference was not found for words (PBW) in the case with RTs of below 0.8 s. Also, it was revealed through the 2-way analysis of variance (ANOVA) test that SNR is the only attentive factor which can affect the Korean speech intelligibilities for both PBW and CVC methods. Therefore, RTs below 0.8 s could be the acoustic criteria for classroom which can minimize the effects of noise. In the case with RTs larger than 0.8 s, much larger SNR is needed to give sufficient speech intelligibility.

• The Journal of Korean Academy of Prosthodontics
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• v.57 no.4
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• pp.448-455
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• 2019

Ameloblastoma is a benign odontogenic epithelial tumor with high recurrence rate and requires extensive resection of the surrounding tissue and reconstruction of defect site. Because of the anatomical limitation of the reconstruction site, prosthetic treatment with implants is the first recommendation. This is a case of prosthetic restoration of the reconstruction site with implant fixed prosthesis in patient who underwent mandibular resection and iliac bone reconstruction due to ameloblastoma. However 14 months after completion of implant prosthesis, adjacent natural tooth erupted unexpectedly, resulting in 1mm infra-occlusion occurred including posterior implant prosthesis and anterior natural teeth. In adults, implant infra-occlusion may occur due to residual growth after placement of the maxillary anterior implant. But this case, hypo-occlusion of molar implant and open bite of anterior natural teeth is occurred due to extrusion of adjacent tooth, is rare. Thus we report the treatment process including orthodontic treatment with intrusion of the posterior tooth, and investigate the causes of sudden, unexpected tooth extrusion.

• Journal of agricultural medicine and community health
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• v.44 no.2
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• pp.82-89
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• 2019

This study was undertaken to determine the seroprevalence and risk factors associated with contracting Lyme disease (LD) among Korean deer farmers. This cross-sectional study devised questionnaire that addressed farm activities, was devised and the blood samples of 516 Korean deer farmers were tested. LD seroprevalence was determined by Western blot test. Fisher's exact test, the chi-squared test, and the chi-squared test for trend analysis were performed to assess the risk associated with LD. Of total 516 study participants recruited, only 12 (2.3%) were seropositive for LD. The result of the study revealed that only deer farmers raising Elk (Cervus Canadensis) were found to be at significantly higher risk of contracting LD than other deer farmers (p=0.033). In addition, a male sex, an age of < 40 years, and those that had raised deer for < 19 years had higher rates of LD infection than their counterparts. Similarly, those that managed livestock sheds, fed deer, processed industry and prepared compost had higher rates of LD infection. In terms of protective factors, those who did not use protective measures such as wear glasses and masks, or protective gloves and aprons, and those that did not disinfect work instruments and did not shower after work had higher rates of LD than those that used protective measures. In conclusion, preventive health strategies should take into account the profiles of deer farmers at greater risk based on considerations of personal, type of work, and the use of personal protective measures.