• Korean Journal of Clinical Laboratory Science
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• v.56 no.1
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• pp.52-58
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• 2024

Photodynamic therapy (PDT) activates intracellular oxygen using a photosensitizer activated by light of a specific wavelength and is a potential means of treating wound infections caused by antibiotic-resistant bacteria. Pseudomonas aeruginosa (P. aeruginosa) is typically non-pathogenic in healthy individuals but can induce severe illnesses like sepsis in the immunocompromised. Antibiotics have been conventionally used to treat P. aeruginosa infections, but increasing antibiotic resistance caused by drug misuse poses a growing challenge to the management of these infections. This study aimed to investigate the ability of PDT using photosensitizers (PhotoMed, Methyl pheophorbide A, or Radachlorin^®) and a diode laser to inhibit P. aeruginosa. Suspensions of P. aeruginosa and a photosensitizer were inoculated into Petri dishes and incubated for 30 minutes. Samples were then irradiated with the laser at 3 J/cm², and after incubation, colony areas were measured. P. aeruginosa killing rates were 79.65% for PhotoMed, 47.36% for Methyl pheophorbide A, and 40.91% for Radachlorin^®. This study shows that PDT using a diode laser and a photosensitizer constitutes an effective practical therapeutic approach for inhibiting P. aeruginosa.

• The Science & Technology
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• v.35 no.12 s.403
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• pp.24-25
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• 2002

연세대 이원영교수는 누에 배설물에서 암세포를 파괴하는 '포르피린'을 발견해 화제를 모으고 있다. 포르피린을 이용한 광역동 치료기술은 광민감제와 빛의 조화로 정상세포가 아닌 암세포만 선택적으로 파괴하여 암치료의 전망을 더욱 밝게하고 있다.

• Proceedings of the Optical Society of Korea Conference
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• 2000.08a
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• pp.216-217
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• 2000

상자성을 갖는 분자에 대한 분광학 연구에서는 제만(Zeeman) 효과로 생기는 이색성을 이용한 magnetic rotation spectroscopy (MRS)가 널리 사용되고 있다.$^{(1)}$ MRS가 일반적인 흡수 분광법에 비해 더 민감한 측정을 할 수 있기는 하지만 사용하는 편광기의 extinction ratio에 의해 감도가 한정된다. MRS의 감도를 높이는 방법으로는 광경로를 길게 만드는 것을 고려할 수 있다. 일반적으로 공진기 광자감쇠 분광학(Cavity Ring-Down Spectroscopy, CRDS)은$^{(2)}$ 높은 반사율을 갖는 거울을 사용해서 수 km 이상의 광 경로를 만들기 때문에 감도가 높다. (중략)

• Proceedings of the Korea Information Processing Society Conference
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• 2012.11a
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• pp.389-392
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• 2012

에너지관리 지원 서비스는 공장 내에서 일어나는 전력발전 및 전력할당을 데어터 분석 기법 등을 이용하여 효과적으로 관리하는 것을 목적으로 한다. 특히 그 중에서도 태양광, 풍력 등 친환경 에너지를 이용한 에너지관리 시스템은 비용절감 뿐만 아니라 환경보호 측면에서도 중요한 문제라 할 수 있다. 이들 친환경 에너지를 제대로 이용하기 위해서는 그들의 발전량을 정확히 예측할 필요가 있지만 현재의 시스템에는 가장 기본적인 예측법인 최근접 이웃법을 사용하고 있다. 최근접 이웃법의 경우 노이즈와 아웃라이어에 민감하다는 단점이 있기 때문에 이들 상황에 대처할 수 있는 보다 정교한 예측법이 필요하다.

• Solar Energy
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• v.13 no.2_3
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• pp.133-139
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• 1993

In this paper, the electrical characteristics of CdS thin films doped with a little of impurities(activators) are studied on wavelength(380-760nm), and temperature($120-360^{\circ}K$). These results are as follows. 1) The resistance of pure CdS thin film increases by annealing, and maximum response value of wavelength is shifted to the long wavelength. 2) The spectral responses of light are more sensitive in low temperature(160K) than in room temperature. 3) Characteristics of the spectral response of light are improved by doping with 0.5wt% impurity.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.12
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• pp.10-15
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• 2020

Ultraviolet rays, which have wavelengths smaller than 400 nm, are very harmful to the eyes. Recently, high-energy visible light was also revealed to be harmful to retinal cells. Therefore, polymer eyeglass lenses that can block UV and high-energy visible light are needed for eye health. In this study, high-refractive-index polymer eyeglass lens, n=1.67, were manufactured using the injection-mold method with the m-xylene diisocyanate monomer, 2,3-bis((2-mercaptoethyl)thio)-1-propanethiol monomer, benzotriazole UV absorber, release of alkyl phosphoric ester, dye mixture of CI solvent violet 13, and catalyst of dibutyltin dichloride mixture. A multi-layer anti-reflection coating was applied to manufactured polymer eyeglass lenses for both sides using an E-beam evaporation system. The optical properties of the manufactured lenses with the UV and high-energy visible light-blocking function were analyzed by UV-visible spectrophotometry. As a result, the polymer eyeglass lens with a UV absorber of 0.5 wt. % blocked 99% of UV and high-energy visible light shorter than 411 nm. The average transmittance of the polymer eyeglass lens with a UV absorber of 0.5wt.% was 97.9% in the range of 460 ~ 660 nm for photopic eye sensitivity higher than 10%. Therefore, clear image acquisition in photopic vision is possible.

• Environmental and Resource Economics Review
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• v.19 no.1
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• pp.159-198
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• 2010

The Korean government is planning to introduce the Renewable Portfolio Standard (RPS) system to replace the currently used Feed-in-Tariff (FIT) system which is a subsidy-based mechanism to foster the renewable energy industry. The RPS system is a market-oriented system in which the power companies are obliged to use renewable energy sources to produce electricity by a certain ratio of their production level. They can either produce for themselves or simply purchase the REC (renewable energy certificate) in the market to implement. The objective of this article is to compare the RPS system with the current FIT system in terms of the implementing cost to achieve the policy goal to expand the share of renewable energy m the total power generation. The analysis is conducted using Linear Programming models. The results of this study imply several policy suggestions to successfully introduce the RPS system.

• Journal of the Korean Institute of Landscape Architecture
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• v.45 no.3
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• pp.1-8
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• 2017

The present study aimed to investigate the effect of calcium chloride($CaCl_2$) on the growth and physiological responses of Pinus strobus and the variables that are sensitive to $CaCl_2$. Thus, changes in the visible damage, growth of root collar diameter, plant water content, chlorophyll content and composition, maximum PS II photochemical efficiency, and electron transport rate of P. strobus was analyzed in relation to treatment witih $CaCl_2$. A $CaCl_2$ solution(0.5, 1.0 and 3.0%) was applied in the root zone before leaf unfolding. Leaf browning, defoliation, and drying were observed with $CaCl_2$ application and this pattern was aggravated as the $CaCl_2$ concentration increased and the treatment period became longer. The decrease of growth in root collar diameter and height and leaf water content were observed at $CaCl_2$ 1.0% and 3.0%. The total chlorophyll content indicated that photopigment, PS II photochemical efficiency and electron transport rate significantly decreased at $CaCl_2$ 3.0%. In conclusion, $CaCl_2$ affected leaf water content and led to a decrease of capability in light harvesting and photochemical responses. Also, as a result of the correlation between calcium chloride concentration and growth and physiological response parameters, it was found that the leaf moisture content and the ratio of chlorophyll a and b reflect the damage level of calcium chloride sensitively because their coefficient of determinations were relatively high.

• Progress in Medical Physics
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• v.16 no.2
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• pp.104-109
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• 2005

Photodynamic therapy (PDT) is one of the expectable current cure operation methods. Tumor tissue is treated by abundant oxygen in a body and generated singlet or free radical from exterior laser diode and photosensitizer. Current problem of PDT is the low penetration power of the light beam in a deep seated large tumor and solid tumor thus results in low treatment outcome. In the study, we tried to develop interstitial photodynamics therapy treatment to solve this problem. As the accurate determination of light dosimetry in biological tissue is one of the most important factors affecting the effectiveness of PDT, parameters used in this study are the optical property of biological tissue. Since biological tissues have large scattering coefficient to visible light the penetration depth of a biological tissue in visible light region is only $15\~20$ mm. We showed that it is possible to measure fluence rate and penetration depth within the biological tissues by Monte Carlo simulation very well. Based on the MC simulation study, the effectiveness of interstitial photodynamic therapy on tumor control in solid tumor was proved through in vivo animal experiment.

• Korean Journal of Agricultural and Forest Meteorology
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• v.2 no.4
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• pp.198-203
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• 2000

This study was conducted to investigate seasonal changes on height, root collar diameter, shoot growth, biomass and chlorophyll contents of Pinus strobus seedlings (two-year old) grown under different light environments in Sangju National University Nursery. Four shade treatments provided seedlings with full sunlight (1800 umo1 m$^{-2}$ s$^{-1}$ ), 75% of full sunlight (1350 umo1 m$^{-2}$ s$^{-1}$ ), 50% of full sunlight (900 ,umo1 m$^{-2}$ s$^{-1}$ ) and 25% of full sunlight (450 umo1 m$^{-2}$ s$^{-1}$ ). Planting density in four light intensities was 30 cm$\times$30cm. In each treatment, 10 trees were planted and height, diameter at root collar, shoot growth, biomass and chlorophyll contents (chlorophyll a, band a+ b) were measured. The highest height, root collar diameter, shoot growth and biomass in Pinus strobus seedlings were observed at full sunlight. Specially, root biomass was the most sensitive tree components part and strongly associated with decreases in the total biomass under low light intensity. The lowest chlorophyll contents (Chlorophyll a, band a+ b) were shown at 25% of sunlight, the lowest light intensity in this study.