• Title/Summary/Keyword: 과학에 대한 태도

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A Protein Structure Comparison System based on PSAML (PSAML을 이용한 단백질 구조 비고 시스템)

  • Kim Jin-Hong;Ahn Geon-Tae;Byun Sang-Hee;Lee Su-Hyun;Lee Myung-Joon
    • Journal of KIISE:Computing Practices and Letters
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    • v.11 no.2
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    • pp.133-148
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    • 2005
  • Since understanding of similarities and differences among protein structures is very important for the study of the relationship between structure and function, many protein structure comparison systems have been developed. Hut, unfortunately, these systems introduce their own protein data derived from the PDB(Protein Data Bank), which are needed in their algorithms for comparing protein structures. In addition, according to the rapid increase in the size of PDB, these systems require much more computation to search for common substructures in their databases. In this paper, we introduce a protein structure comparison system named WS4E(A Web-Based Searching Substructures of Secondary Structure Elements) based on a PSAML database which stores PSAML documents using the eXist open XML DBMS. PSAML(Protein Structure Abstraction Markup Language) is an XML representation of protein data, describing a protein structure as the secondary structures of the protein and their relationships. Using the PSAML database, the WS4E provides web services searching for common substructures among proteins represented in PSAML. In addition, to reduce the number of candidate protein structures to be compared in the PSAML database, we used topology strings which contain the spatial information of secondary structures in a protein.

Study on the Characteristics of DNA Comet Assay for Irradiated Vegetables and Grains (방사선조사된 채소류 및 곡물류의 DNA Comet Assay 특성 연구)

  • Seo, Jung-Eun;Oh, Se-Wook;Kim, Yun-Ji;Lee, Nam-Hyouck;Hong, Sang-Pill;Kim, Young-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.4
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    • pp.472-476
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    • 2008
  • The possibility of DNA comet assay as a rapid method for screening the irradiated vegetables and grains was evaluated. Vegetables (spring onion, garlic, and tomato) irradiated at $0{\sim}3$ kGy and grains (rice flour and black soybean) irradiated at $0{\sim}9$ kGy were used as samples. Optimum DNA comet assay conditions, such as elution, sedimentation of suspension, and lysis time of cell, were established. The optimum conditions for vegetables were 10 min for the elution time, 0 min for the sedimentation time, and 5 min for the lysis time. The optimum conditions for grains were 15 min for the elution time, 60 min for the sedimentation time, and 30 min for the lysis time. For the food application of DNA comet assay, it was possible to screen various food samples irradiated at the following doses: spring onion at 2 kGy, garlic at 3 kGy, tomato at 1 kGy, rice flour at 9 kGy, and black soybean at 3 kGy. Each sample showed different forms and sizes in DNA comet. Therefore, further studies on various methods using comet shape, concentration, or area in DNA comet assay are necessary.

A Qualitative Study on the Process of Group Mentoring -With a Focus on the Types of Relationships among Participants- (집단멘토링의 참여과정에 관한 연구 -멘티의 관계 유형을 중심으로-)

  • Park, Hyun-Sun;Lee, Hyun-Joo;Seo, Min-Jeong
    • Journal of the Korean Society of Child Welfare
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    • no.40
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    • pp.323-351
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    • 2012
  • The purpose of this study is to analyze the process of relationships among participants in a group mentoring program. Sixteen youths who participated as mentees in a group mentoring program were theoretically sampled and participated in in-depth interviews. The analysis was based on Strauss and Corbin's grounded theory approach(1990). The result shows that the qualitative text data were classified into 14 categories and 31 sub-categories. Four different types of mentees' experiences were identified: 'expanded mentoring relationship', 'peer-oriented relationship', 'task-oriented relationship' and 'avoidant relationship'. Through a process analysis, four stages including 'stage of exploring', 'stage of establishing relations', 'stage of conflict' and 'stage of expanding relations' were discovered. Implications for social work intervention and policy development were discussed based on these findings.

A Study on the Factors Affect on Opticians' Customer Orientation (안경사의 고객지향성에 영향을 미치는 요인에 관한 연구)

  • Choi, Youngro;Park, Inn-Jee
    • The Korean Journal of Vision Science
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    • v.20 no.4
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    • pp.403-411
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    • 2018
  • Purpose : The purpose of this study is to analyze how the certain efforts of the optical shops affect on opticians' job satisfaction and organizational commitment, and to analyze how opticians' job satisfaction and organizational commitment affect on the customer orientation and to suggest the method of maintaining competitiveness. Methods : Two hundred opticians took participations on the surveys via the Internet survey method and social network system (SNS), and SPSS 18.0 statistics program was used for data analysis; frequency analysis, T-test, factor analysis, reliability analysis, and multiple linear regression analysis were conducted. Results : It is analyzed the differences on the job satisfaction and organizational commitment in accordance with type of optical shops, conducting 5 working days/week and flexible time. As a result, higher job satisfaction is presented with 5 working days/week. Relationships with co-workers statistically affect on job satisfaction positively and emotional labor and work overload statistically affect on job satisfaction negatively. In addition, relationships with co-workers and reward statistically affect on organizational commitment positively and emotional labor and work overload statistically affect on organizational commitment negatively. And opticians' job satisfaction and organizational commitment statistically affect on customer satisfaction positively. Conclusion : It is necessary for the optical shops to make an effort for their opticians to improve the job satisfaction and organizational commitment. And to do so, it is needed to form trusting and respecting relationships with co-workers or superiors. In addition, it is necessary to have continuous communication and education for opticians' self-management. Also, it is needed to establish an effective reward system.

Ulmus macrocarpa Hance Reduces Cyclophosphamide-induced Toxicity in Mouse Liver (Cyclophosphamide가 유발한 간 조직변화에 대한 느릅나무 열수추출물의 완화 효과)

  • Kim, Deok Won;Chung, Kyung Tae
    • Journal of Life Science
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    • v.31 no.2
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    • pp.223-228
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    • 2021
  • Cyclophosphamide (CP) is widely used in cancer and lymphoma treatments and as an immunosuppressant drug. CP is a DNA alkylating agent that metabolizes into 4-hydrocyclophosphamide (4H-CYP) and aldophosphamide in hepatocytes. However, its metabolites cause DNA synthesis disorder, leading to apoptosis and toxic side effects. The development of technology to minimize this side effect is essential to improve CP's clinical application. Various bioactive compounds have been reported to have anti-cancer and antioxidant functions and preventive or therapeutic roles in metabolic diseases. Many researchers have attempted to minimize the side effects and improve the efficacy of these drugs together with the use of bioactive compounds. Ulmus macrocarpa Hance has been used for the treatment of edema, mastitis, stomach pain, tumors, cystitis, and other inflammatory diseases. The aim of this study was to investigate at the histological level the protective function of U. macrocarpa Hance against CP's side effects and any potential toxic effect of U. macrocarpa Hance in the liver and kidney. Water extracts of U. macrocarpa Hance reduced CP-induced toxicity and did not induce any histological damage in the liver and kidney. Therefore, U. macrocarpa Hance would be applicable in the pharmaceutical industry.

Simulation of Vessel Movement in Ancient Port of Hwaseong Coast Using Marine Physics Model (해양물리모델을 이용한 화성 연안 고대포구의 선박 이동 모의)

  • Lee, Seungtae;Han, Min;Yang, Dong-Yoon;Cho, Yang-Ki;Park, Chanhyeok;Yu, Jaehyung
    • Economic and Environmental Geology
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    • v.55 no.2
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    • pp.137-148
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    • 2022
  • In this study, ship movement simulation was performed based on a marine physics model for the ancient port presumed under the past environmental conditions in the coastal area of Hwaseong, which played an important role as a center of trade in the Three Kingdoms and Unified Silla periods. The paleo topographical surface was reconstructed through the analysis of borehole sediments, and the paleo coastline was extracted through the geomorphological maps published during before independence. Based on the established paleo environmental conditions of the Hwaseong coast, the marine physics model (FVCOM) was used to simulate the flow of surface currents and the route of floating materials assumed to be ancient ships. As a result, the processes of moving ships from the port to the open sea in the Eunsupo area, which is estimated location of the ancient port related to Dangseong, was well simulated, and thus the reliability of the location of the ancient port estimated by the scientific method was secured. This study is significant as a result of convergence research that encompasses archeology, history, geomorpology, geology, and oceanography.

Analysis of Forest Fire Damage Areas Using Spectral Reflectance of the Vegetation (식생의 분광 반사특성을 이용한 산불 피해지 분석)

  • Choi, Seung-Pil;Kim, Dong-Hee;Ryutaro, Tateishi
    • Journal of Korean Society for Geospatial Information Science
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    • v.14 no.2 s.36
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    • pp.89-94
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    • 2006
  • Forest damage is a worldwide issue and specially, a forest fire involves damage to itself and causes secondary damage such as a flood etc. However, actually, clear analysis on forest fire damage can be hardly conducted due to difficulty in approaching a forest fire and quite a long period of time for analysis. To overcome such difficulty, recently, forest fire damage has been actively investigated with satellite image data, but it is also difficult to obtain satellite image data fitted to the time a forest fire occurred. In addition, it is burdensome to verify accuracy of the obtained image. Therefore, this study was attempted to look into the damaged districts from forest fires by reference to spectroradiometric characteristics of the obtained vegetation with a spectroradiometer as preliminary work to use satellite image data. To begin with, the researcher analyzed the field survey data each measured 3 months and 6 months after occurrence of a forest fire by judging the extent of the damage through visual observation and using a spectroradiometer in order to investigate any potential errors arising out of one-time visual observation. Besides, in this study, groups showing possibilities that trees might be restored to life and wither to death could be classified on the sampling points where forest fire damage is minor.

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Spirometry Reference Equations for Asian Migrant Workers in Korea: A Proposal (아시아 외국인 근로자의 폐활량검사 결과해석을 위한 예측식 제안)

  • Hwa-Yeon LEE;Yonglim WON
    • Korean Journal of Clinical Laboratory Science
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    • v.55 no.1
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    • pp.29-36
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    • 2023
  • This study proposes a spirometry reference equation suitable for Asian migrant workers undergoing special health examinations. The study participants were divided according to their region: Central Asia, Northeast Asia, and South Asia Pacific. We confirmed results of the spirometry analysis of migrant workers and the interpretation consistency between the prediction equations. Based on this data, we propose a reference equation suitable for domestic migrant workers and suggest a scaling factor applicable to the spirometer wherein the reference equation is not easily applicable. The kappa-values obtained for men and women, respectively, between the global lung function initiative 2012 (GLI2012)-Southeast Asian and the Southeast Asian equations were 0.819 and 0.770, between the GLI2012-Southeast Asian and the South Asian equations were 0.881 and 0.866, and between the GLI2012-Northeast Asian and the Central Asian equations were 0.831 and 0.833. We propose applying the GLI2012-Northeast Asian equation for Northeast Asian and Central Asian countries, whereas the GLI2012-Southeast Asian equation was found to be more suitable for predicting Southeast Asian and South Asian populations. For spirometry, we recommend applying a scaling factor of 0.87 to the Dr. Choi equation, wherein the GLI2012-Southeast Asian equation is not applicable.

Transhumanism and Life-World: From the Perspective of Husserl's Phenomenology (트랜스휴머니즘과 생활세계: 후설 현상학의 관점에서)

  • Park, In-Cheol
    • Journal of Korean Philosophical Society
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    • no.126
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    • pp.85-115
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    • 2019
  • With the dramatic development of science and technology since the twentieth century, attempts to overcome human's natural and physical limitations through technology have actually reached a peak. Transhumanism is a movement that strongly affirms these human technological attempts. However, this optimistic belief of transhumanism in technology meets the strong resistance of opponents contending that transhumanism might destroy human nature and severely undermine human values and rights. The focus of the transhumanism debate lies in what technology means to humans. However, in order to exactly grasp the essence of transhumanism, we should first consider our 'life-world', where technology and humans are closely intertwined. The word 'life-world(Lebenswelt)' which originally comes from Husserl, is an open and universal world as a horizon that is the basis of all human practical activities and at the same time encompasses its products in itself. According to Husserl, the process of incorporating human products into the life-world is a kind of 'familiarization' process through which specific theories and techniques are harmonized with our lives in the life-world. Such harmonization and familiarization of technology could be also considered a humanization of technology. It is a process in which technology is assimilated and corresponds to the finiteness of human and the life-world. In this sense, we could say that the transhumanistic attempts are just a natural expression of human desire to be perfect in the life-world and that they should not be overly concerned or overestimated.

Study on the Effects of Shop Choice Properties on Brand Attitudes: Focus on Six Major Coffee Shop Brands (점포선택속성이 브랜드 태도에 미치는 영향에 관한 연구: 6개 메이저 브랜드 커피전문점을 중심으로)

  • Yi, Weon-Ho;Kim, Su-Ok;Lee, Sang-Youn;Youn, Myoung-Kil
    • Journal of Distribution Science
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    • v.10 no.3
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    • pp.51-61
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    • 2012
  • This study seeks to understand how the choice of a coffee shop is related to a customer's loyalty and which characteristics of a shop influence this choice. It considers large-sized coffee shops brands whose market scale has gradually grown. The users' choice of shop is determined by price, employee service, shop location, and shop atmosphere. The study investigated the effects of these four properties on the brand attitudes of coffee shops. The effects were found to vary depending on users' characteristics. The properties with the largest influence were shop atmosphere and shop location Therefore, the purpose of the study was to examine the properties that could help coffee shops get loyal customers, and the choice properties that could satisfy consumers' desires The study examined consumers' perceptions of shop properties at selection of coffee shop and the difference between perceptual difference and coffee brand in order to investigate customers' desires and needs and to suggest ways that could supply products and service. The research methodology consisted of two parts: normative and empirical research, which includes empirical analysis and statistical analysis. In this study, a statistical analysis of the empirical research was carried out. The study theoretically confirmed the shop choice properties by reviewing previous studies and performed an empirical analysis including cross tabulation based on secondary material. The findings were as follows: First, coffee shop choice properties varied by gender. Price advantage influenced the choice of both men and women; men preferred nearer coffee shops where they could buy coffee easily and more conveniently than women did. The atmosphere of the coffee shop had the greatest influence on both men and women, and shop atmosphere was thought to be the most important for age analysis. In the past, customers selected coffee shops solely to drink coffee. Now, they select the coffee shop according to its interior, menu variety, and atmosphere owing to improved quality and service of coffee shop brands. Second, the prices of the brands did not vary much because the coffee shops were similarly priced. The service was thought to be more important and to elevate service quality so that price and employee service and other properties did not have a great influence on shop choice. However, those working in the farming, forestry, fishery, and livestock industries were more concerned with the price than the shop atmosphere. College and graduate school students were also affected by inexpensive price. Third, shop choice properties varied depending on income. The shop location and shop atmosphere had a greater influence on shop choice. The customers in an income bracket of less than 2 million won selected low-price coffee shops more than those earning 6 million won or more. Therefore, price advantage had no relation with difference in income. The higher income group was not affected by employee service. Fourth, shop choice properties varied depending on place. For instance, customers at Ulsan were the most affected by the price, and the ones at Busan were the least affected. The shop location had the greatest influence among all of the properties. Among the places surveyed, Gwangju had the least influence. The alternate use of space in a coffee shop was thought to be important in all the cities under consideration. The customers at Ulsan were not affected by employee service, and they selected coffee shops according to quality and preference of shop atmosphere. Lastly, the price factor was found to be a little higher than other factors when customers frequently selected brands according to shop properties. Customers at Gwangju reacted to discounts more than those in other cities did, and the former gave less priority to the quality and taste of coffee. Brand preference varied depending on coffee shop location. Customers at Busan selected brands according to the coffee shop location, and those at Ulsan were not influenced by employee kindness and specialty. The implications of this study are that franchise coffee shop businesses should focus on customers rather than aggressive marketing strategies that increase the number of coffee shops. Thus, they should create an environment with a good atmosphere and set up coffee shops in places that customers have good access to. This study has some limitations. First, the respondents were concentrated in metropolitan areas. Secondary data showed that the number of respondents at Seoul was much more than that at Gyeonggi-do. Furthermore, the number of respondents at Gyeonggi-do was much more than those at the six major cities in the nation. Thus, the regional sample was not representative enough of the population. Second, respondents' ratio was used as a measurement scale to test the perception of shop choice properties and brand preference. The difficulties arose when examining the relation between these properties and brand preference, as well as when understanding the difference between groups. Therefore, future research should seek to address some of the shortcomings of this study: If the coffee shops are being expanded to local areas, then a questionnaire survey of consumers at small cities in local areas shall be conducted to collect primary material. In particular, variables of the questionnaire survey shall be measured using Likert scales in order to include perception on shop choice properties, brand preference, and repurchase. Therefore, correlation analysis, multi-regression, and ANOVA shall be used for empirical analysis and to investigate consumers' attitudes and behavior in detail.

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