• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 1999.10a
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• pp.29-29
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• 1999

점화천이(Ignition transient)는 일반적으로 점화 신호를 주는 순간부터 로켓모타가 평형상태(equilibrium) 혹은 설계 작동조건에 도달했을 때까지의 시간 구간으로 정의되며, 이 시간 동안에 높은 연소실 압력 증가율에 의한 동연소효과(dynamic burning effect)와 연소가스의 높은 cross-flow 속도에 의한 침식연소효과(erosive burning effect)에 의해 추진제의 연소증가 현상을 일으킨다. 이런 두가지의 증가된 연소효과와 더불어 과대하게 설계된 점화기로부터 유입되는 질량유량에 의해 연소실을 채우는 시간(Chamber filling) 중에 압력 과잉(pressure overshoot)이 나타난다 그러나 동연소효과 및 침식연소효과의 경우 추진제의 종류와 로켓모타의 형상 등에 의해서 복합적으로 나타나는 현상이기 때문에 모든 로켓모타에 대해서 공통으로 적용할 수식이나 방정식이 존재하지 않는다.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2013.10a
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• pp.563-563
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• 2013

Railway noise has been a social issues nowadays in our community. This paper discusses the environmental noise problem along railway lines. We overview the noise level and noise exposed populations due to conventional and high speed train operation at first. Then we introduce variety of noise reduction schemes to protect the community based on an engineering approach. Some applicationcases to reduce the noise will be demonstrated. Finally, we propose the noise barrier tunnel as a tool of a generic solution to reduce the community noise along railway lines.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2000.11a
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• pp.82-87
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• 2000

During the operation, fatigue failures and cracks of duct plate due to excessive duct vibration occurred in the fan-duct systems of fossil fueled boilers. We measured static pressure variation(pressure pulsation) in the outlet, and also measured vibration at the outlet duct of a centrifugal fan. It was found that strong pressure pulsation caused by the inlet vortex occurred in inlet vane of centrifugal fan in the middle range of vane opening. Thus, excessive duct vibration is caused by strong pressure pulsation. In this paper, it is shown that the frequency and amplitude of pressure pulsation depend mainly on vane opening and are compared with duct vibration. Also, effective solution for reducing pressure pulsation and vibration are presented.

• Journal of Life Science
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• v.31 no.6
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• pp.550-558
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• 2021

Fructus Corni, the fruit of Cornus officinalis, has long been used for the prevention and treatment of various diseases. We recently suggested that it was effective against benign prostatic hyperplasia (BPH). In this study, we investigated the inhibitory effect of Corni Fructus (CF) water extract on BPH induced by testosterone propionate (TP) in noncastrated and castrated animal models. BPH was induced in Sprague Dawley rats by an intramuscular injection of TP in castrated or noncastrated rats. Finasteride (FINA) treatment was used as a positive control for inhibition of BPH. According to our results, CF administration inhibited excessive enlargement of development of the prostate in both the noncastrated and castrated groups compared to the control and FINA-treated groups. The inhibitory effect of CF on BPH was associated with inhibition of expression of hypoxia-inducible factor-1α, 5α-reductase type 2, steroid receptor coactivator-1, androgen receptor (AR), and prostate-specific antigen. Serum levels of the stress hormone cortisol increased during BPH induction by TP in both the noncastrated and castrated groups, but they were attenuated significantly by CF administration. However, insulin and IGF-1 levels were not increased in the BPH-induced groups and CF, and no effective results were found by CF administration. These results point to a beneficial effect of CF on BPH through inhibition of AR signaling pathway activity and imply that CF shows excellent potential as a therapeutic agent for the prevention and treatment of BPH.

• Journal of Ocean Engineering and Technology
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• v.6 no.1
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• pp.131-139
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• 1992

The understanding and appllication of fatigue crack propagation mechanism in variable amplitude loading is very important for life prediction of the air travel structures. Particularly, the retardation and arrest behavior of fatigue crack propagation by single tension overloading is essential to the understanding and appllication of fatigue crack propagation mechanism in variable amplitude loading. Numerous studies of the retardation behavior have been performed, however investigations of the arrest behavior have not been enough yet. As for the arrest behavior, Willenborg had reported that the overload shut-off ratio $[R_{so}=(K_{OL})/K_{max})_{crack arrest}]$ had been the material constant, but recently several investigators have reported that the overload shut-off ratio depends upon the stress ratio. In this study, authors have investigated the effect of stress ratio on the threshold overload shut-off ratio to generate arrest of fatigue crack growth in high tensile aluminum alloy 7075-T735 which have used in material for air travel structures, It has been $-0.4\leqqR\leqq0.4$ till now, the region of stress ratio investigated. The threshold overload shut-off ratio has decreased as stress ratio has increased in overall region of -$-0.4\leqqR\leqq0.4$ and the linearity has been seen in this material. Moreover, the experimental equation between $R_{so}$ and R has been made; The relation has been $R_{so}=-R+2.6$.

• Journal of the Korean Society of Propulsion Engineers
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• v.18 no.4
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• pp.1-8
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• 2014

Overexpanded flow of an axisymmetric thruster nozzle is numerically simulated to investigate effects of nozzle pressure ratio (NPR) on the shock structure and thrust performance. The Reynolds-averaged Navier-Stokes equations with k-${\omega}$ SST turbulence model are solved utilizing FLUENT solver. As the NPR is raised, thrust performance monotonically increases with the shock structure and flow-separation point being pushed toward the nozzle exit. It is also discussed that the flow structure at nozzle-exit plane which is immediately affected by a position of nozzle-interior shocks and expansion waves, has strong influence upon the thrust performance of thruster nozzle.

• Journal of Animal Reproduction and Biotechnology
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• v.34 no.1
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• pp.30-34
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• 2019

Milk fever is a metabolic disease with manifestation of clinical signs due to hypocalcemia, which usually occurs within 48-72 h after delivery. However, even after a successful treatment of milk fever, recurrence of milk fever may occur, and studies on recurrent milk fever are still lacking. Accordingly, the present study was conducted for the purpose of identifying the characteristics of recurrent milk fever according to farm, season, parity, and dystocia that can cause physiological changes in the mother during peri- and postpartum periods. The analysis results showed that the incidence rate of initial and recurrent milk fever according to breeding farm was 5.7%-14.1% and 3.1%-7.2%, respectively, demonstrating a positive correlation between the initial and recurrent milk fever (r = 0.613, p < 0.01). With respect to season, the incidence rate of initial and recurrent milk fever during summer was 12.3% and 7.5%, respectively, which were significantly higher than that of other seasons (p < 0.05). In addition, the recurrence rate, the ratio of recurrence relative to initial milk fever, was highest during summer with 62.7%. Regarding parity, the incidence rate of initial and recurrent milk fever in 3rd parity was 11.1% and 5.8%, respectively, which was significantly higher than in 1st and 2nd parity (p < 0.05). Furthermore, the recurrence rate in 4th parity was 64.1%, showing a pattern of increase in incidence rate with increase in parity. Finally, there were no differences in the incidence rate of initial and recurrent milk fever according to eutocia and dystocia. The findings indicated that the incidence rate of initial milk fever should be reduced to effectively prevent the recurrent milk fever, while animals with 3rd parity or higher should be expected to occur high rate of recurrent milk fever, especially during summer, and the necessary preparations should be made for intensive treatment of such individuals.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.34 no.4
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• pp.24-36
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• 2021

Objectives : This study was conducted to confirm the anti-oxidative effect of Chungpyesagan-tang(CPSGT) extract. Methods : In this study, MTT assay was performed to confirm cell viability, and DPPH and ABTS were performed to confirm radical scavenging ability. The ROS scavenging ability and the protective effect against DNA damage were confirmed by 2,7-dichlorofluorescin diacetate(DCF-DA) and 4',6-diamidino-2-phenylindole(DAPI) staining and comet assay. mRNA expression of Heme oxygenase-1(HO-1) was measured by real-time PCR, and expression of HO-1 and Kelch-like ECH-associated protein 1(Keap1) proteins was measured by western blot. Results : CPSGT was not cytotoxic at 50-400㎍/㎖. The radical scavenging activity was increased, and the ROS scavenging activity and the protective effect against DNA damage were increased compared to the LPS-treated group. The mRNA expression and protein expression of HO-1 were increased in a concentration-dependent manner. The protein expression level of Keap1 was decreased in a concentration-dependent manner. Conclusion : This suggests that CPSGT has an antioxidant effect and can be used as a potential material for skin diseases.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.34 no.2
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• pp.1-20
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• 2021

Objective : The object of this study was to assess the efficacy of hydrolysate from Phellinus igniarius(HPI) on anti-aging activities in vitro measurement and mini clinical study performed on 5 subjects. Methods : To evaluate skin anti-aging efficacy of HPI, 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging activity, type I collagen synthesis, inhibition of nitric oxide(NO) production, inhibiton of tyrosinase, hyaluronan synthase(HAS)2, 3 mRNA expression were measured in vitro. Also, mini clinical study of skin hydration was performed on 5 subjects using HPI in distilled water(DW) and 1,3-butylene glycol diluted solution(30% in DW). Results : 1. DPPH radical scavenging activity of HPI was increased in a dose-dependant. 2. Type I collagen synthesis was increased in 50, 100 and 500㎍/㎖ of HPI. 3. NO production was not inhibited in all concentrations of HPI. 4. Tyrosinase was inhibited in 500, 1000, 2500 and 5000㎍/㎖ of HPI. 5. HAS2 mRNA expression was increased in 50, 100, 150 and 200㎍/㎖ of HPI, HAS3 mRNA expression was increased in 100, 150, and 200㎍/㎖ of HPI. 6. In the mini clinical study of 5 subjects, there was a difference in skin hydration over time for each solutions, but it was not statistically siginificant. Conclusions : HPI increased DPPH radical scavenging activity, type I collagen synthesis, and HAS2, HAS3 mRNA expression. HPI also suppressed tyrosinase. The findings of this study suggest that HPI can be used as an skin anti-aging material.

• Journal of the Korean Geotechnical Society
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• v.24 no.3
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• pp.13-23
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• 2008

In a nonlinear site response analysis which is performed in time domain, small strain damping is modeled as viscous damping through use of various forms of Rayleigh damping formulations. Small strain damping of soil is known to be independent of the loading frequency, but the viscous damping is greatly influenced by the loading frequency. The type of Rayleigh damping formulation has a pronounced influence on the dependence. This paper performs a series of nonlinear analyses to evaluate the degree of influence of the viscous damping formulation on Korean soil profiles. Analyses highlight the strong influence of the viscous damping formulation for soil profiles exceeding 30 m in thickness, commonly used in simplified Rayleigh damping formulation overestimating energy dissipation at high frequencies due to artificially introduced damping. When using the full Rayleigh damping formulation and carefully selecting the optimum modes, the artificial damping is greatly reduced. Results are further compared to equivalent linear analyses. The equivalent linear analyses can overestimate the peak ground acceleration even for shallow profiles less than 20 m in thickness.