• Title/Summary/Keyword: 골격구조

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칠성장어 (Lampetra japonica)젖 산수소이 탈효소 동위효소의 정제 및 면역화학

  • Jo, Seong-Gyu;Park, Seon-Yeong;Yeom, Jeong-Ju
    • The Korean Journal of Zoology
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    • v.36 no.4
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    • pp.505-513
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    • 1993
  • 칠성장어(Lampetro juponico) 골격근의 젖산수소이탈효소(EC 1. 1. 1.27, Lactate dehvdrogenase LDH) 동위효소 꺽지(Coreoperco herzi)의 LDH Aa 동위효소 및 소(Bos taurus)의 LDH B4 동위효소를 affinity chromatography로 정제하였고, 대구(Gadus macrocephcfus)의 LDH Ca 동위효소를 affinity chromatography와 OEAE-Sephacel chromatography로 정제하였다. 칠성장어 골격근 LDH 동위효소는 affinity chromatography에서 buffer를 유입한 후 용출되는 분획에서 모두 확인되었고, 정제한 칠성장어 골격근의 LDH에 대한 항체는 꺽지 LDH A4, C4 및 54 동위효소, 대구 LDH A4 및 B4 동위효소 그리고 생쥐(MUS musculus) LDH A4 등위효소와 복합체를 형성하였다. 칠성장어 골격근조직에서는 비각우 및 Ldh절가 발현되고 하부단위체 A의 구조는 하부단위체 B의 구조와 유사하며, 하부단위체 A는 진화상 보존적 이지만 하부단위체 C는 진화속도가 상당히 빠른 것으로 사료된다.

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A Study on the Exoskeleton Robot Operations to Assist the Upper Limbs Power (상지 근력 증강을 위한 외골격 로봇의 동작기법 연구)

  • Choi, Jae-Heung;Oh, Seong-Nam;Chu, Kyong-Ho;Son, Young-Ik;Kim, Kab-Il
    • Proceedings of the KIEE Conference
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    • 2011.07a
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    • pp.1918-1919
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    • 2011
  • 상체 지원 외골격 로봇은 크게 인간의 근력을 보조하는 형태와 인간의 근력을 증강하는 형태가 있다. 여기서는 인간의 근력을 증강하는 외골격 로봇을 중심으로 기술하고자 한다. 이러한 외골격 로봇은 팔의 EMG (Electromyograph;근전도) 신호를 측정하는 방법보다는 손의 힘을 직접 감지하는 방법을 통한 팔꿈치와 어깨의 엑추에이터를 구동하는 방식을 취하는 경향이 있다. 본 논문에서도 후자의 방식을 이용하여 손에 작용하는 힘을 분석하여 외골격 로봇을 움직이는 방식을 취하였다. 손의 힘 중에서도 인간을 중심으로 볼 때 위방향과 전진방향의 힘을 분석하기 위하여 2개의 F/T(Force/Torque) 센서를 사용하였으며 팔을 벌리는 동작은 엑추에이터 없이 자유롭게 동작이 가능하도록 설계하였다. 이러한 위방향 및 전진방향 힘의 크기를 팔꿈치와 어깨의 엑추에이터의 동작으로 바꾸어 인간의 동작을 도울 수 있고 힘을 증폭할 수 있는 외골격 로봇을 설계 제작하였다. F/T 센서는 손의 힘을 전기적 신호로 바꾸어주는 로드셀로 이루어지며 손의 힘을 최대한 잘 반영하기 위한 구조를 고안하였다. F/T 센서의 전기신호는 증폭기를 거쳐서 잡음을 제거한 후에 A/D 변환하여 processor에서 처리되어진다.

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COMPARATIVE STUDY ON MUSCLE ACTIVITIES OF PRE- AND POST-ORTHOGNATHIG SURGERY IN SKELETAL CLASS III MALOCCLUSION PATIENTS AND NORMAL GROUP (성인에서 골격형 제 III급 부정교합자의 악교정 수술 전, 후와 정상교합자의 근활성도에 대한 비교연구)

  • Jung, Kyung-Jin;Sohn, Byung-Wha
    • The korean journal of orthodontics
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    • v.25 no.3 s.50
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    • pp.355-373
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    • 1995
  • Craniofacial region is a musculodentoskeletal system that consists of many anatomical structures ; cranioskeletal structures, dental arches, and formation and functions of masticatory muscles have close correlations. Growth and development of craniofacial region are influenced by not only hereditory factors, but also environmental factors such as craniofacial muscles and surrounding tissues. On the contrary, however, study on changes in functions or adaptations of craniofacial muscles following changes of craniofacial skeletal structures has been somewhat insufficient. The author's purpose was to observe correlations between masticatory muscular functions and change patterns according to cranial skeletal structures and occlusion patterns, for this, comparative study of muscle activity changes of preand post- orthognathic surgery states in skeletal Cl III malocclusion patients was peformed. The selected sample groups were 15 normal male patients, 15 skeletal Cl III pre-orthognatic surgery patients and 15 skeletal Cl III post-orthognatic surgery patients. For each sample groups, cephalometric x-ray taking, masticatory efficiency test and measurements of muscle activities in anterior temporal muscle, masseter and upper lip in rest, clenching, chewing and swallowing were carried out. The following results were obtained : 1. In resting state of mandible, pre-surgery malocclusion group showed higher m. activities in ant. temporalis, masseter and upper lip than post-surgery group. Post-surg. malocc. group showed significantly high m. activity only in upper lip compared to the normal group. 2. In clenching state, post-surg. malocc. group showed higher m. activities in ut. temporalis, masseter and upper lip than pre-surg. malocc. group. 3. In chewing state, post-surg. malocc. group showed higher m. activities in ant. temporalis and masseter than pre-surg. malocc. group, on the other hand, decreased upper lip activity was noticed. 4. In swallowing state, post-surg. malocc. group showed lower upper lip activity than pre-surg. malocc. group but higher than that of the normal group. No significant difference in m. activities of ant, temporalis and masseter was noticed among the three groups. 5. Masticatory efficiency was lower in pre-surg. malocc. group than normal group, masticatory efficiency showed an increase in post-surg. malocc. group compared to the pre-surg. malocc. group. However, both groups showed significant differences compared to the normal group.

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Fine Structure and Immunogoldlabeling of Crystalline Inclusion Bodies in Mitochondria (미토콘드리아내 결정함유물의 미세구조 및 면액황금표식법)

  • ;;R.A. Capaldi
    • The Korean Journal of Zoology
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    • v.31 no.1
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    • pp.62-70
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    • 1988
  • The distribution of respiratory chain complexes in beef heart and human muscle mitochondria has been explored by immunoeledron microscopy with antibodies made against beef heart mltochondriai proteins in conjundion with protein A cofloidai gold (l2nm particles). The antibodies used were made against NADH-conezyme Q reductase(complex I), ubiquinol-cytochrome-c-oxldoreductase (complex III) and cytochrome-c-oxidase(complex IV). Labeling of bed heart tissue with any of these antihodies gave gold particles randomly distributed along the mitochondrial inner membrane. The labeling of muscle tIssue mitochondria from a patient with a mitochondrial myopathy localized by biochemical analysis to complex III was quantitated and compared with the labeling of human control muscle tissue mitochondria. Four kinds of morphological changes in the mitochondrial fine strudure in the myopathy patient tissue have been found; paracrystalline inclusions consistIng of densely packed multi- lamellar structures, globular crystalline inclusions with high electron density, multilamellar strudure inclusion body(compadly and irregularly arranged concentric whirl shaped cristae)and golbular cyrstalilne inclusions located in the center of the whirl shaped cristae. Compex I and cytochrome-c-oxldase antihodies reacted to the same level in the mitochondria containing the crystalline inclusions and control mitochondria. Antibodies to complex III reacted very poorly to the mitochondria containing the crystalline Inclusions but strongly to control mitchondria. The globular crystalline inclusions in the mitochondria are not reacted antibodies to respiratory chain complexes.

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근골격계 질환 예방을 위한 시스템적 접근과 추진전략

  • 정은교
    • Bulletin of the Korean Institute for Industrial Safety
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    • v.3 no.1
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    • pp.18-24
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    • 2003
  • 최근 산업사회의 급속한 환경변화는 근로자의 상병구조에서도 나타나 작업이 단순반복화 되며 다양한 작업공구를 반복적으로 사용하게 되어 작업속도와 작업량이 많아지고 운동부족으로 인한 근력의 약화 등에 의해서 근골격계질환이 급속히 증가하고 있다. 이로 인한 근로자의 삶의 질은 물론 결근에 의한 노동력 손실, 제품불량 증가, 산재보상비용 지출증가 등으로 성장을 둔화시키고 사회$.$경제적으로 문제의 심각성을 더해주고 있다. 최근 노동부가 발표한 산업재해통계를 보면 2002년도 산업재해 중 업무상질병자는 5,417명으로 전년대비 136명 감소하였으나, 이중 직업성 근골격계질 환자(신체부담작업 및 요통)는 1,827명으로 전년대비 193명(11.8%) 증가한 것으로 나타났고, 그 발생양상이 집단적이라는 특성을 갖고 있다. 이처럼 직업성 근골격계질환의 업무상 질병에서 차지하는 비율이 증가추세에 있고 대부분의 선진국에서도 과거에는 각종 화학물질에 의한 직업병이 상위를 차지해 오다가 근래에는 동 질환이 업무상질병의 상당부분 이상으로 차지하고 있다. 미국의 경우 1998년 한해동안 253,300건(64.2%) 발생하였고 이 가운데 자동차 관련업종이 가장 많은 비율을 점유하고 있다.(중략)

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Shear Behaviour of Sand-silt Mixture under Low and High Confining Pressures (모래-실트 혼합토의 구속압력에 따른 전단특성 파악)

  • Kim, Uk-Gie;Zhuang, Li
    • Journal of the Korean Geotechnical Society
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    • v.31 no.3
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    • pp.27-38
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    • 2015
  • Triaxial tests on sand-silt mixture specimens under low and high confining pressures were performed to understand their shear behaviors. The fines content in the mixture is lower than the threshold value. A series of tests under different conditions including fines contents (0%, 9.8%, 14.7%, 19.6%), density of specimen (controlled by different compaction energies of $E_c=22kJ/m^3$, $E_c=504kJ/m^3$), confining pressure (100 kPa, 1 MPa, 3 MPa, 5 MPa) were performed to investigate influences of these factors. Based on the test results, the threshold fines content, where the dominant structure of mixture changes from sand-matrix to fines-matrix, decreases with the increase of confining pressure. Under very high confining pressures, as a result of sand particle crushing, the behavior of the dense specimen is similar to that of the loose specimen which shows hardening, compression behavior, and shear strength increases with increase of fines content. In conclusion, silt is granular material like sand, and its influence on shear behavior of sand-silt mixture is very different from that of plastic fines on sand-fines mixture.

Extraskeletal Paraarticular Osteochondroma of the Knee - A Case Report - (슬관절에 발생한 골격골외 관절주변 골연골종 - 1례 보고 -)

  • Han, Chung-Soo;Park, Yong-Koo;Park, Hyun-Chul;Kim, Jin-Yong;Kwak, Sang-Joon;Park, Cheol-Hee;Park, Jin-Sung
    • The Journal of the Korean bone and joint tumor society
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    • v.15 no.2
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    • pp.146-150
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    • 2009
  • Osteochondromas typically arise from the metaphyseal ends of long bones. Extraskeletal paraarticular osteochondromas are unusual osteocartilaginous lesions that arise in the soft tissue adjacent to a joint with no bony continuity. We present a case of pathologically proven extraskeletal paraarticular synovial osteochondroma of the knee observed in 42-year-old female with a literature review.

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A STUDY OF THE CHARACTERISTICS OF CRANIOFACIAL SKELETON ON ORTHOGNATHIC SURGICAL GASES WITH SKELETAL GLASS III MALOGGLUSION (악교정술을 요하는 골격성 III급 부정교합자의 악안면 골격 특성에 관한 연구)

  • Lim, Han-Ho;Yoon, Young-Jooh;Kim, Kwang-Won
    • The korean journal of orthodontics
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    • v.28 no.2 s.67
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    • pp.189-201
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    • 1998
  • The purpose of this study was to evaluate the characteristics of craniofacial skeleton on orthognathic surgical cases with skeletal Class III malocclusion. For this study, 74 students at the dental college of Chosun University volunteered as a normal occlusion group. They had well-balanced faces and good occlusions with acceptable Class I molar relationship. They had not received orthodontic treatment and had no signs or symptoms of temporomandibular joint dysfunction. 45 malocclusion patients enrolled for orthognathic surgical treatment with skeletal Class III malocclusion at the Department of Orthodontics, College of Dentistry, Chosun University. On the basis of this study. the results of this study were as follows: 1. Skeletal Class III malocclusion was largely due to the overgrowth of mandible in man and the undergrowth of maxilla in woman. 2. The mandible was antero-inferiorly overgrown by large MP-HP angle and large genial angle in orthognathic surgical cases with skeletal Class III malocclusion. And also, upper incisors were severely labioversioned, but on the other hand lower incisors were linguoversioned. 3. In female, lower-third facial height was characteristically shortened in comparison with middle-third facial height and also, lower facial throat angle was small in male.

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Rearrangement of Korean Terms for Insect Head Morphology (곤충 머리 부위에 대한 우리말 용어 재조명)

  • Lee, Young In
    • Korean journal of applied entomology
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    • v.57 no.4
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    • pp.279-285
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    • 2018
  • Different English terms indicating a same part in insect head were arranged according to position and function, and their corresponding different Korean terms were suggested. The terms include lines on head surface, head regions of embryo, external and internal skeletons, internal parts of mouth, long mouths, external parts and basic segments of antenna, antennal shapes, and hairs on surface.

Development of a Digital Textbook on 'Structure and Contraction Mechanism of Skeletal Muscle' with the Learning Model for Biomimicry-Based Convergence (생체모방 기반 융합 학습 모델을 적용한 '골격근의 구조와 수축'에 대한 디지털 교재 개발)

  • Kim, Soo-Youn;Kwon, Yong-Ju
    • Journal of Science Education
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    • v.42 no.2
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    • pp.95-105
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    • 2018
  • The purpose of this study was to develop a digital textbook on 'structure and contraction mechanism of skeletal muscle' with the learning model for biomimicry-based convergence. The unit of 'structure and contraction mechanism of skeletal muscle' is a part of Life Science I in high school. The convergence learning model was designed with three phases of biomimicry-based convergence (Exploration-Design-Implementation) including 3D modeling & printing. The developed digital textbook was composed of 8 sessions which contains the following learning contents : Exploration of skeletal muscle, creative designing of skeletal muscle using sketch application and 3D modeling, convergent implementing of the designed using 3D printing, exploration of muscle contraction, creative designing of muscle contraction using sketch application and 3D modeling, and convergent implementing of the designed using 3D printing. Each session is also involved in the contents of gallery widgets, media widgets, keynote widgets, sketch widgets, the cloud, polling widgets, and review widgets for interactive and mobile learning. After administering the developed digital textbook to 20 high school students, it was shown a positive effectiveness on life science learning for high school students. Moreover, the digital textbook was evaluated as to promote student's abilities on creative designs and implementation related to biomimicry-based convergence. The digital textbook was also shown a favorable response on students' interest and self-directed learning on life science.