• Proceedings of the Korea Information Processing Society Conference
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• 2009.04a
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• pp.1186-1189
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• 2009

본 논문에서는 이동 애드 혹 네트워크의 성능 개선을 위한 방안으로 네트워크 중간에 고정 노드를 부가하여 어느 정도의 성능 향상이 있는지를 모의 실험을 통하여 평가하였다. 모의 실험 결과 이동 노드만을 사용했을 경우보다 고정노드를 함께 사용했을 때의 성능이 더 뛰어남을 알 수 있었고, 이동 노드의 이동 속도에 따른 비교에서도 고정 노드를 함께 사용한 경우가 성능이 더 뛰어남을 확인할 수 있었다. 또한 고정 노드의 개수에 따른 성능평가에서는 고정 노드를 여러 대 사용할수록 지연시간이 단축됨을 확인 할 수 있었다. 본 연구에서 제안한 방식은 이동 애드 혹 네트워크의 중간에 고정 노드를 부가하여야 하는 문제가 있으나, 비용과 처리율과의 관계를 비교한 후 비용 상승에도 불구하고 보다 높은 신뢰성과 빠른 처리율을 원하는 네트워크에 사용하면 효과적일 것이다. 향 후 본 절의 연구 결과에 이어서 애드 혹 네트워크에 몇 대의 고정 노드를 추가해야 하는지에 대한 연구가 이루어진다면 보다 높은 신뢰성을 가진 애드 혹 네트워크가 구축될 수 있을 것이다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.8
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• pp.417-424
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• 2019

Despite its superior ability to show distinct cellular morphology and for long-term storage, conventional tissue fixation by formalin has many drawback, including slower fixation, the exposure to harmful chemicals and extensive protein modification. Herein, we assessed the effects of rapid microwave-assisted tissue fixation on histological examination and on protein integrity by comparing these microwave irradiation fixated tissues with the formalin-fixed tissues. One of the paired mouse tissues (liver and kidney) was fixed in formalin and the other was fixed by using microwave irradiation in phosphate buffered saline. Each slide from the paraffin-embedded tissues was examined by H & E staining for the adequacy of fixation and by immunohistochemical staining for antigenicity in a blinded fashion. Evaluation of protein recovery and the protein quality from the fixed tissues were analyzed by the BCA method and Western blotting, respectively. The results from H & E staining and immunohistochemical staining showed that the sections obtained from microwave-fixed tissues under our experimental conditions were comparable to those of the formalin-fixed tissues except for the integrity of RBCs. Furthermore, proteins were effectively extracted from the microwave-fixed tissues with acceptable preservation of the proteins' quality. Taken together, this microwave-assisted tissue processing yields a quick fixation and better protein recovery in higher amounts, as well as the adequacy of fixation and the antigenicity being comparable to formalin-fixed tissues, and this all suggests that this new fixation technique can be applied in an environment where rapid tissue fixation is required.

• The Korean Journal of Applied Statistics
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• v.10 no.1
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• pp.177-187
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• 1997

This article considers the power performance of the tests in unbalanced two way mixed linear models with one fixed factor. The generalized least squares (GLS) F statistic testing no differences among the effects of the levels of the fixed factor is estimated using Henderson's method III, minimum norm quadratic unbiased estimator (MINQUE) with prior guess 1, maximum likelihood (ML) and resticted maximum likelihood (REML). We investigate the power performance of these test statistics. It can be shown, through simulation, that the GLS F statistics using four estimators produce similar type I error rates and power performance.

• The Academic Congress of Korean Shoulder and Elbow Society
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• 2009.03a
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• pp.185-185
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• 2009

관절와 및 상완골의 의미 있는 골결손을 동반한 불안정한 견관절에 대해 어떻게 최선의 치료를 할 것인가에 대한 의문은 남아있다. 어떤 저자들은 외회전과 외전을 제한하는 것으로 Hill-Sachs 병변의 진입을 예방하는 일종의 관혈적 관절낭 변위를 통한 제한된 상완와관절 운동을 주장해왔으며, 다른 관혈적 시술들은 극하근건과 관절낭을 Hill-Sachs 병변 내로 관혈적 전이시키는 것으로 기술되어왔다. 최근에는 여러 저자들에 의해 Hill-Sachs 병변의 진입을 치료하는 더 새로운 접근법들이 기술되었으며, Bankart 병변 복원술에 더하여 Hill-Sachs 병변을 채우기 위해 관절경 하 후방 관절낭 고정술과 극하근건 고정술로 이루어진 이른바 'Remplissage'술기가 소개된 바 있어, 이에 저자는 외상성 견관절 불안정성으로 관절경 하 Bankart 병변 복원술 및 관절낭 축화술 시행 후 외상으로 재발된 견관절 불안정성이 발생하여 관절경 하 Bankart 병변 복원술과 함께'Remplissage'술기를 이용한 Hill-Sachs 병변 복원술을 시행한 예를 보고하는 바이다.

• Korean Journal of Food Science and Technology
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• v.29 no.2
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• pp.320-325
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• 1997

Transglucosidase (TG) from Aspergillus niger was immobilized on various carriers by several immobilization methods such as ionic binding, adsorption, entrapment, covalent linkage and metal chelation to improve the process performance. The covalent linkage with CNBr-activated sepharose 4B was found as the best method for immobilization of TG based on the immobilization yield which was 61.3%. The immobilization through ionic binding and adsorption gave 33.1% and 22.5% yield respectively but both methods were not selected due to lower yield than covalent linkage using CNBr-Sepharose 4B. Internal diffusion resistance in beads developed by entrapment were not suitable factor in producing final target products. Covalent linkage of TG on magnesium silicate, silica gel and glass bead and metal chelation method didn't result in higher yield than the selected one, either.

• Korean Journal of Food Science and Technology
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• v.11 no.3
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• pp.192-199
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• 1979

With cells of Streptomyces spp K-45 isolated from soil, the immobilization of glucose isomerase by a series of treatments ; heat, carefully manipulated drying, extrusion with a thickening agent, and glutaraldehyde-induced crosslinking, was presented. This was aimed to obtain a mechanically stable form of whole cell containing glucose isomerase. The resulted pellet form had a good mechanical strength, compared with a commercial product, and showed 26 % of the activity recovery. The specific activity was 48.1 units per g of the dry material. The immobilized glucose isomerase generally showed properties similar to those of the soluble enzyme ; optimal pH at $7.5{\sim}9.0$, optimal temperature at $80{\sim}85^{\circ}C$, activation energy of 10.9 kcal/mole, and $K_m$ for glucose of 10.9M. The immobilized enzyme was very thermostable and pH stable.

• The Journal of Korean Academy of Prosthodontics
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• v.61 no.4
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• pp.328-343
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• 2023

Recently, a method of fabricating an esthetic anterior fixed prosthesis by integrating data such as three-dimensional facial scan and jaw motion to form a virtual patient with dynamic occlusion has been introduced. This enables smooth communication with patients during the diagnosis process, improves the predictability of esthetic prosthetic treatment, and lowers the possibility of occlusal adjustment. In this case report, a virtual patient with dynamic occlusion was created in which the results of the treatment were simulated, and esthetic maxillary anterior fixed prosthesis was fabricated. With the aid of the virtual patient, the final restorations were satisfactory both in terms of esthetic and function.

• Journal of Biomedical Engineering Research
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• v.20 no.6
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• pp.547-553
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• 1999

생체재료로 사용되는 polyurethane(PU) 표면에 항혈전성 lumbrokinase(LK)를 고정함으로써 생체적합성을 향상시키고자하였다. 먼저 LK를 PU 표면에 고정하기 위한 가교제로서 4-azidoaniline hydrochloride와 poly(acrylic acid)를 이용하여 4-azidophenyl 작용기가 amido 결합으로 치환된 수용성, 광반응성 poly(acrylic acid)(PPa-II)를 합성하였다. H-nuclear magnetic reasonance spectrum(500MHz H-NMR)의 6-7 peak와 infrared spectrum (FT-IR) 의 2125.48 cm peak으로부터 PPA-II의 합성을 지원하였다. EH한 4-azidophenyl 작용기가 poly(acrylid acid) 잔기에 치환된 정도는 UV/VIS adpectrophotometric spectrum을 확인한 결과 11~14%임을 알 수있었다. 0.5 1및 5% PPA-II를 각각 광반응하여 얻은 PU는 39.5, 161.8 및 181.5 nmole/$\textrm{cm}^2$의 농도로 표면에 carvoxyl 작용기가 유도되었음을 알 수있었다. 0.05M KH2PO4 (pH 4.5) 용액에서 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide(EDC)를 촉매로 사용하여 LK를 PU표면에 amido 공유결합으로 고정하였으며, 이것은 지속적인 fibrinolytic 활성도를 보였다. PPA-II를 이용한 표면 개질 방법은 수용성 반응조건에서 이루어진다는 점과 광반응을 이용함으로써 특정부위에서의 표면개질이 가능하다는 점에서 그 응용가치가 크며 아울러 PU의 생체적합성을 향상시킬 수 있는 방법으로서 판단된다.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 1986.12a
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• pp.520.3-521
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• 1986

L-Lysine 생성균인 Corynebacterium glutamicum의 동종간 융합주 RS 99를 담체인 Alginate와 여기에 TiCl$_4$로부터 제조된 Titanium hydroxide를 혼합하여 각각 고정하고 이들의 Gel strength, 활성도 및 회분식 발효조건을 비교하였다. 그 결과 Alginate-Titanium hydroxide를 담체로 선정하여 고정화 C, glutamicum 융합주의 재사용성 및 안정성을 검토하였으며, Continuous-Flow Stirred-Tank Reactor를 구성하여 L-Lysine 의 연속발효를 시도하였다.

• The Journal of Korean Society for Radiation Therapy
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• v.20 no.1
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• pp.1-9
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• 2008

Purpose: For head and neck cancer patients treated with radiation therapy, proper immobilization of intra-oral structures is crucial in reproducing treatment positions and optimizing dose distribution. We produced a man-made tongue immobilization device for each patient subjected to this study. Reproducibility of treatment positions and dose distributions at air-and-tissue interface were compared using man-made tongue immobilization devices and conventional tongue-bites. Materials and Methods: Dental alginate and putty were used in producing man-made tongue immobilization devices. In order to evaluate reproducibility of treatment positions, all patients were CT-simulated, and linac-gram was repeated 5 times with each patient in the treatment position. An acrylic phantom was devised in order to evaluate safety of man-made tongue immobilization devices. Air, water, alginate and putty were placed in the phantom and dose distributions at air-and-tissue interface were calculated using Pinnacle (version 7.6c, Phillips, USA) and measured with EBT film. Two different field sizes (3$\times$3 cm and 5$\times$5 cm) were used for comparison. Results: Evaluation of linac grams showed reproducibility of a treatment position was 4 times more accurate with man-made tongue immobilization devices compared with conventional tongue bites. Patients felt more comfortable using customized tongue immobilization devices during radiation treatment. Air-and-tissue interface dose distributions calculated using Pinnacle were 7.78% and 0.56% for 3$\times$3 cm field and 5$\times$5 cm field respectively. Dose distributions measured with EBT (international specialty products, USA) film were 36.5% and 11.8% for 3$\times$3 cm field and 5$\times$5 cm field respectively. Values from EBT film were higher. Conclusion: Using man-made tongue immobilization devices made of dental alginate and putty in treatment of head and neck cancer patients showed higher reproducibility of treatment position compared with using conventional mouth pieces. Man-made immobilization devices can help optimizing air-and-tissue interface dose distributions and compensating limited accuracy of radiotherapy planning systems in calculating air-tissue interface dose distributions.