• Radiation Oncology Journal
• /
• v.23 no.3
• /
• pp.143-156
• /
• 2005

Background: The best dose-fractionation regimen of the definitive radiotherapy for cervix cancer remains to be clearly determined. It seems to be partially attributed to the complexity of the affecting factors and the lack of detailed information on external and intra-cavitary fractionation. To find optimal practice guidelines, our experiences of the combination of external beam radiotherapy (EBRT) and high-dose-rate intracavitary brachytherapy (HDR-ICBT) were reviewed with detailed information of the various treatment parameters obtained from a large cohort of women treated homogeneously at a single institute. Materials and Methods: The subjects were 743 cervical cancer patients (Stage IB 198, IIA 77, IIB 364, IIIA 7, IIIB 89 and IVA 8) treated by radiotherapy alone, between 1990 and 1996. A total external beam radiotherapy (EBRT) dose of $23.4\~59.4$ Gy (Median 45.0) was delivered to the whole pelvis. High-dose-rate intracavitary brachytherapy (HDR-IBT) was also peformed using various fractionation schemes. A Midline block (MLB) was initiated after the delivery of $14.4\~43.2$ Gy (Median 36.0) of EBRT in 495 patients, while In the other 248 patients EBRT could not be used due to slow tumor regression or the huge initial bulk of tumor. The point A, actual bladder & rectal doses were individually assessed in all patients. The biologically effective dose (BED) to the tumor ($\alpha/\beta$=10) and late-responding tissues ($\alpha/\beta$=3) for both EBRT and HDR-ICBT were calculated. The total BED values to point A, the actual bladder and rectal reference points were the summation of the EBRT and HDR-ICBT. In addition to all the details on dose-fractionation, the other factors (i.e. the overall treatment time, physicians preference) that can affect the schedule of the definitive radiotherapy were also thoroughly analyzed. The association between MD-BED $Gy_3$ and the risk of complication was assessed using serial multiple logistic regression models. The associations between R-BED $Gy_3$ and rectal complications and between V-BED $Gy_3$ and bladder complications were assessed using multiple logistic regression models after adjustment for age, stage, tumor size and treatment duration. Serial Coxs proportional hazard regression models were used to estimate the relative risks of recurrence due to MD-BED $Gy_{10}$, and the treatment duration. Results: The overall complication rate for RTOG Grades $1\~4$ toxicities was $33.1\%$. The 5-year actuarial pelvic control rate for ail 743 patients was $83\%$. The midline cumulative BED dose, which is the sum of external midline BED and HDR-ICBT point A BED, ranged from 62.0 to 121.9 $Gy_{10}$ (median 93.0) for tumors and from 93.6 to 187.3 $Gy_3$ (median 137.6) for late responding tissues. The median cumulative values of actual rectal (R-BED $Gy_3$) and bladder Point BED (V-BED $Gy_3$) were 118.7 $Gy_3$ (range $48.8\~265.2$) and 126.1 $Gy_3$ (range: $54.9\~267.5$), respectively. MD-BED $Gy_3$ showed a good correlation with rectal (p=0.003), but not with bladder complications (p=0.095). R-BED $Gy_3$ had a very strong association (p=<0.0001), and was more predictive of rectal complications than A-BED $Gy_3$. B-BED $Gy_3$ also showed significance in the prediction of bladder complications in a trend test (p=0.0298). No statistically significant dose-response relationship for pelvic control was observed. The Sandwich and Continuous techniques, which differ according to when the ICR was inserted during the EBRT and due to the physicians preference, showed no differences in the local control and complication rates; there were also no differences in the 3 vs. 5 Gy fraction size of HDR-ICBT. Conclusion: The main reasons optimal dose-fractionation guidelines are not easily established is due to the absence of a dose-response relationship for tumor control as a result of the high-dose gradient of HDR-ICBT, individual differences In tumor responses to radiation therapy and the complexity of affecting factors. Therefore, in our opinion, there is a necessity for individualized tailored therapy, along with general guidelines, in the definitive radiation treatment for cervix cancer. This study also demonstrated the strong predictive value of actual rectal and bladder reference dosing therefore, vaginal gauze packing might be very Important. To maintain the BED dose to less than the threshold resulting in complication, early midline shielding, the HDR-ICBT total dose and fractional dose reduction should be considered.

• Korean Journal of Soil Science and Fertilizer
• /
• v.37 no.5
• /
• pp.304-314
• /
• 2004

The objective of this study was to investigate the effect of organic materials (compost, straw, green manure, pig manure, seed production oil cake, and industrial by products including municipal sewage sludge, industrial sewage sludge, leather processing sludge, and alcohol fermentation processing sludge) on physical properties of soils in seven paddy and four upland fields with differential soil textures, sandy loam, loam, or clay loam, etc. The investigated physical parameters were bulk density (BD), air permeability (AP), macroporosity, hardness, shear resistance, frictional resistance, water stability aggregate (WSA), and Middleton's dispersion ratio. Except for coarse sandy loam field with weak structure, a decrease in BD and shear resistance, and an increase in macroporosity and AP in plots with applying organic materials compared to plots without applying organic materials appeared. In upland fields, the positive effect of organic materials on WSA, BD, and air permeability was higher than in paddy fields. The combined plot of NPK and compost had lower BD, hardness, and shear resistance, and higher macroporosity and WSA than plot with compost. Green manure had higher positive effect on physical properties of soils compared to other organic materials and the extent of positive effect had no significant correlation with soil organic matter content. Of industrial byproducts applied in coarse sandy loam soil under upland condition, municipal sewage sludge and pig manure compost had higher effect on increase of WSA than leather processing sludge and alcohol fermentation processing sludge. Unlike WSA, there were no significant differences between industrial byproduct types in other physical properties. in silty clay loam soil under the upland condition, straw had more positive effect on soil physical parameters than hairy vetch and pig manure. Therefore, different organic materials had differently active effect on physical parameters depending on types of soil and land use. Especially, it could be thought that well-decomposed organic materials have the advantage of an increase in organic matter content, while coarse organic materials of an increase in WSA.

• Journal of the Korean Geotechnical Society
• /
• v.28 no.7
• /
• pp.41-53
• /
• 2012

During rainfall period, to identify the characteristics of the infiltration of moisture, electrical resistivity monitering survey was carried out to weathered zone. Four regions of geophysical exploration areas with different rock types, four regions were selected. An area consists of mafic granite and three areas are composed of sedimentary rocks (Sandstone, Shale, Unconsolidated Mudstone). Survey was conducted from June (rainy season) to November (dry season), and during the period the change in resistivity was observed. According to the result of monitoring exploration on Geumjeong and Jinju areas, for the estimation of the standard rainfall, it is necessary to estimate the effects of the antecedent rainfall during the rainy season based on the overall rainfall from June till October and also necessary to consider this for the estimation of the half period. Also, the vertical distribution of the low resistivity anomaly zone does not show that the infiltration of moisture does not occur uniformly from the surface of the ground to the lower ground but shows that it occurs along the relaxed gap of the crack or soil stratum of the weathering zone. In Pohang area, the type of moisture infiltration is different from that of the granite or sedimentary rock. Since, after the rainfall, the rate of infiltration to the lower ground is high and the period of cultivation to the lower bedrock aquifer is short, it has similar effect to that of the antecedent rainfall applied for the estimation of the standard rainfall being presently used. In Danyang, due to the degree of water content of the ground, the duration period of the low resistivity anomaly zone observed in the lower ground of the place where clastic sedimentary rock is distributed is similar to that in Pohang area. The degree of lateral water diffusion at the time of localized heavy rain is the same as that of the sedimentary rock in Jinju. According to the above analysis results, in Danyang area, the period when the antecedent rainfall has its influence is estimated as three weeks or so.

• Journal of Korean Home Economics Education Association
• /
• v.27 no.4
• /
• pp.19-35
• /
• 2015

The purpose of this study was to develop and evaluate a teaching learning process plan for the practice of caring and sharing to improve character of highschool students through Home Economics subject. The teaching learning process plan consisting of 13-session lessons has been developed and implemented according to the ADDIE model for the unit of 'Happy Family Life and Culture led by Family'. The unit was divided into two themes: Theme I caring through sharing and Theme II caring through practice. Six practice elements of caring and sharing such as communication, gratitude, courage, love, empathy, and environment drawn from Theme I are applied to Theme II. Various activities and teaching materials as well as questionnaire were developed. The plan was applied to 8 classes, 287 freshmen of S highschool in Jeonju-si from March to May, 2014. Three factors were drawn from 35 character-related items: self-perception, perception of caring and sharing, and practice of caring and sharing. These factors were related to respondents' satisfaction with family relationships and school life. Two factors except self-perception improved through 13 lessons. Students evaluated that the whole caring and sharing practice lessons of Theme I and II gave them the chance to realize a actual practice in everyday life was important even with small efforts such as cooking for special family. Also students commented that the praising workbook was impressive. All 23 items of evaluation gained from over 3.5 to 4.2 on 5-point scale. It can be concluded that the teaching learning process plan for the practice of caring and sharing for the unit of 'Happy Family Life and Culture led by Family' would improve character of highschool students through the Home Economics subject.

• Journal of the Korean Institute of Landscape Architecture
• /
• v.44 no.2
• /
• pp.52-69
• /
• 2016

The fishing port was once the foothold of production as well as the stronghold of communities but with the declining of the fishing industry, ports became abandoned space. Jeju Special Self-Governing Province has continued its effort to vitalize marine tourism since 2010. Shinyang Port in particular is designated as a Prearranged Marina Port Development Zone, and planning for the Jeju Ocean Marina City project is underway. Nevertheless, fishing port remodeling projects implemented on Jeju so far have focused only on civil engineering such as renovating old facilities. In addition, most Marina Port Development Projects have been irrelevant to local communities. Leading projects by the local government mostly suffer from a lack of funding, which results in the renovation of old facilities and improper maintenance, while private sector investment projects do not lead to benefit sharing with the community. Shinyang Port, also renovated in 2008, ended up with outer breakwater extension construction that neither solved the fundamental problem of the site nor gave benefits to residents. To arrange a way to solve problems for civil engineering focused development project, improper maintenance, and benefit sharing with community, first, this study proposes a development plan that connects with the outlying areas near the ports. The plan reflects existing topography, Jeju traditional stonewalls, narrow paths on the master plan and programs by reading the regional context. In this way, this paper suggests a space development plan reflecting the local landscape and characteristic factors. Second, it satisfies various needs by using existing and new Marine Tourism Resources. Third, it examines sustainable operation and management measures through residents' participation. The proposal is significant in two key ways: it is a fresh attempt at connecting the fishing port with its outlying areas from a landscape perspective; and it considers environmental, social, economic issues, and suggests participation for local communities. Thus, the model can be used in future fishing-port remodeling plans for revitalizing unused space, including invaluable traditional landscapes, and for boosting the marine-leisure industry.

• The Journal of Korean Academy of Prosthodontics
• /
• v.51 no.4
• /
• pp.269-275
• /
• 2013

Purpose: The aim of this retrospective study was to evaluate the influence of implant diameter, length and placement to implant stability. Materials and methods: Total 90 implants (US II plus$^{TM}$, Osstem co, Busan, Korea) of 72 patients were determined as experimental samples. The factors of diameters(${\phi}$ 4 mm, ${\phi}$ 5 mm), lengths (10 mm, 11.5 mm, 13 mm), and implant placement (maxilla, mandible) were analyzed. The stability of the implants was measured by resonance frequency analysis (RFA) at the time of implant placement and impression taking. The difference of ISQ values according to patient's gender was evaluated by Independent t-test. ISQ values were compared between implant diameter, length and placement using one-way ANOVA and Tukey HSD test (${\alpha}=.05$). To compare ISQ values between at the time of surgery and impression taking, paired t-tests were used (${\alpha}=.05$). Results: The change of implant length did not show significant different on the ISQ value (P>.05). However, 5 mm diameter implants had higher ISQ values than 4 mm diameter implants (P<.05). Implants placed on the mandible showed significantly higher ISQ values than on the maxilla (P<.05). Conclusion: In order to increase implant stability, it is better to select the wider implant, and implants placed on mandible are possible to get higher stability than maxilla. ISQ values at impression taking showed higher implant stability than ISQ values at implant placement, it means that RFA is clinically effective method to evaluate the change of implant stability through the osseointegration. The consideration of the factors which may affect to the implant stability will help to determine the time of load applying and increase the implant success rate.

• Journal of Bio-Environment Control
• /
• v.22 no.4
• /
• pp.371-377
• /
• 2013

The government has been carrying out a project for supporting the rain shelter for hot pepper as part of measures stabilizing the demand and supply of hot pepper since 2012. However, the eaves height of single-span plastic greenhouses extensively used in farms is low, which are inappropriate for the rainproof cultivation of hot pepper. This study attempted to develop single-span plastic greenhouses which are structurally safe and have the dimensions suitable for the rainproof cultivation of hot pepper as well. The structure status of plastic greenhouses and restructuring wishes of 56 rainproof cultivation farms nationwide were investigated to set up the width and height of the plastic greenhouses. 53% of the plastic greenhouses currently in operation had a width of under 7 m and 64% of their eaves had a height of 1.5 m or less, which accounted for the highest rate. Mostly the width of 7.0 m was desired for the greenhouses and the height of 2.0 m for their eaves, so these values were chosen as the dimensions for the singlespan plastic greenhouses. After an analysis of their structural safety while changing the specifications of the rafter pipe in various ways, 5 kinds of models were suggested considering the frame ratio and installation costs. The 12-Pepper-1 model is a developed single-span plastic greenhouse for hot pepper in which a ${\emptyset}42.2{\times}2.1t$ rafter pipe is installed at an interval of 90cm and the models of 12-Pepper-2 through 5 are the other developed ones in which a ${\emptyset}31.8{\times}1.5t$ rafter pipe is installed at intervals of 60 cm, 70 cm, 80 cm and 90 cm, respectively. As a result of an analysis of economic feasibility of 12-Pepper-2 compared to 10-Single-3 in the notification of the Ministry for Food, Agriculture, Forestry and Fisheries, it turned out that there would be an increase in profits by about 1.2 million won based on one building of a greenhouse sized 672 $m^2$.

• Journal of the Korean Chemical Society
• /
• v.56 no.6
• /
• pp.751-758
• /
• 2012

In this study, we analyzed career paths and college life plans of department of chemistry education students in teacher's college examined by their roadmaps. We let students make their roadmaps and analyzed them using the PASW 18 program. There were significant differences on gender in their career paths, learning English, traveling and volunteer activity. Female students for passing the MEET(Medical Education Eligibility Test) or DEET(Dental Education Eligibility Test) were more interested in learning English and traveling than male students. In addition, female students were more interested in volunteer activity. And the lower year students, the more interested in medical paths, learning English, traveling, getting good grades, exchange student program and scholarship. On the other hand the higher year students, the more interested in group study or E-learning. Then significant differences were in learning English, traveling and getting good grades by students's career paths. Students who wish to pass the MEET or DEET were more interested in learning English and getting good grades. Those two factors were essential in passing the MEET or DEET. Students who did not specified their career paths had more traveling plans than other students for setting their directions of careers. These results show that freshman and female students don't recognize the identity of teacher's college correctly. Because of reduction in the number of teacher recruitment according to decrease of students by birth rate drop, students in teacher's college are expected to continue like this trend that students look for other paths. Therefore, it is required career counseling and guidance for students who give priority practical path choices and college life plans over original characteristics of teacher's college. And it should be reconsidered the direction of chemistry education prepared the identity of teacher's college reflected in this actuality.

• Journal of the Korean Institute of Traditional Landscape Architecture
• /
• v.37 no.4
• /
• pp.1-10
• /
• 2019

The purpose of this study is to examine the design ＆ construction methods of the traditional landscape space of the past and the repair and maintenance of cultural heritages to maintain it today. To this end, the method of narrative description, process extraction and construction related to traditional landscaping were compared to each other based on the 『Imwongyeongjeji』 「Seomyongji」 and 'Standard Specification for Repairing Cultural Heritages'. The results are as follows; First, to analyze at the description methods of the 『Imwongyeongjeji』 「Seomyongji」 and 'Standard Specification for Repairing Cultural Heritages' and related processes in the field of traditional landscaping. 『Imwongyeongjeji』 「Seomyongji」 was an encyclopedia of the overall construction method of the living space, describing the location, effect, and advantages and disadvantages of each component and presenting quantitative figures to institutionalize the construction of traditional landscaping spaces. 'Standard Specification for Repairing Cultural Heritages' presented the entire process of repairing cultural heritages, and it is becoming a kind of guide for reference at the site. Among them, foundation construction, roof construction, landscape construction, and fence construction were drawn as items that could be applied to traditional landscaping areas. Second, the traditional landscape space construction method was divided into the processes of foundation construction, roof construction, landscaping construction, and fence construction. Foundation construction is a way of repeating the process of land-tramping. During the construction of the roof, the tile-roofed building was built on top of the rafters and roofed with tiles. And thatched roof was made to a number of rice straws bundles to cover the roof one after the other. Instead of tiles, the stone roof was made of thin and wide stones, and the wooden boards were used for the single roof and the bark roof were constructed with many layers of dried corrugations. Landscape construction mainly consists of the Paving technique through tramping rubble and the construction of terraced flower by planting stone, plants, and shrubs on the top. According to the building materials, the wall construction was derived from the earth-stacked earthen wall, stone walls using stone and clay, marble walls made of tile patterns, and the construction of a board wall using a wood board as a wall. Third, comparing the construction methods of the 『Imwongyeongjeji』 「Seomyongji」 and 'Standard Specification for Repairing Cultural Heritages', 『Imwongyeongjeji』 「Seomyongji」 focuses on standardizing the construction methods to create a new traditional space. There is a difference in the setting of the scope of the 『Imwongyeongjeji』 「Seomyongji」 and the construction because 'Standard Specification for Repairing Cultural Heritages' provides the overall construction procedure considering the diversity of the cultural heritages. In addition, the traditional landscape space used to be a residential space in the past, but today, the maintenance process of the already established facilities as designated cultural heritages has been carried out, and construction methods have been added to create viewing conditions. In terms of the succession of traditional knowledge, some similar methods were found in the repair of cultural assets today, and some cases were also confirmed in the reconstruction of traditional technologies such as application of some materials or mix, separation of added facilities and introduction of efficient construction methods.

• Korean Journal of Environment and Ecology
• /
• v.30 no.1
• /
• pp.130-134
• /
• 2016

How does $CO_2$ affect on the stomatal mechanism? The mechanism of stomatal opening by $CO_2$ is not clear as it is difficult to see $CO_2$ effect on light-induced stomatal opening. Furthermore, stomata may react differently according to the concentration of $CO_2$. The significance of the possible endogenous rhythms must consider to understand on $CO_2$-related response. It is clear that $CO_2$ has an effect on the accumulation of osmotic materials which determines the degree of stomatal apertures because it is known that stomata open in the condition of the reduced $CO_2$ concentration. However, it is not fully understood how $CO_2$ leads to the stomatal opening. It has been thought that $CO_2$ can not affect on the ion fluxes which determines the increase of osmotic potential in guard cells. However, in this study, the changes of guard cell membrane permeability by $CO_2$ have been focused on. There are many reports that $CO_2$ related reactions are dominant when the leaf is exposed to certain a mount of $CO_2$. The hypothesis of the stomatal opening by light is based on the increase of osmotic materials in guard cells including $K^+$, $Cl^-$, sucrose and $malate^{2-}$. It was reported that $CO_2$ induced a big hyperpolarization indicating that $H^+$ was extruded to the cell outside. It was also found that $CO_2$ caused guard cell membrane hyperpolarization in the intact leaf up to 3 or 4 times higher than that of light induced membrane hyperpolarization. These results represent that $CO_2$ can affect on the change of physical characteristics which affects on the change of the membrane permeability.