• Journal of Ginseng Research
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• v.31 no.2
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• pp.79-85
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• 2007

Compound K (CK) is a final metabolite of panaxadiol ginsenosides. Although panax ginseng is known to have anti-diabetic activity, the active ingredient is not yet fully identified. Therefore, it would be interesting to know whether and how CK has an anti-diabetic activity. First, insulin secretion-stimulating activity of CK was examined using RIN-m5F cell line and primary cultured islets. CK enhanced the insulin secretion in a concentration dependent manner. This effect, however, was almost completely abolished in the presence of diazoxide, $K^+$ channel opener, indicating that the insulin secretion-stimulating activity of CK is presumably due to blockade of ATP sensitive $K^+$ channel. In addition, effects of CK on gene expressions of hepatic enzymes (phosphoenolpyruvate carboxykinase[PEPCK], glucose-6-phos-phatase[G6Pase]) and on adipocyte differentiation in H4IIE and 3T3-Ll cells, respectively, were examined. CK suppressed the induction of PEPCK and G6Pase mRNA expressions under the dexamethasone/cAMP stimulation condition. CK also reduced the $PPAR-{\gamma}$ mRNA expression and triglyceride accumulation in a dose dependent manner as compared to the control. The present study suggests that CK deserves to examine whether it shows an anti-diabetic activity in animal and human studies.

• The Korean Journal of Mycology
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• v.19 no.1
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• pp.79-84
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• 1991

Fruit bodies of Ganoderma lucidum have been used for most pharmacological studies, but pharmacological effects are likely variable because the habitats and strains of Ganoderma lucidum are different. Therefore, their fermentation is required to produce constant and reliable pharmacolo­gical constituents from Ganoderma lucidum. During the studies of medium for industrial application. it was found that ginseng root residues, remaining after being extracted with ethanol, were a good carbon source for a fermentation of Genoderma lucidum and a corn steep liquor was also economical for the nitrogen source. Yield of the mycelial cultured in ginseng root residues and corn steep liquor was 2.5 times higher than that in glucose and peptone, known as a conventional medium of Ganoderma lucidum. The polysaccharide content of the extracts from the cultured mycelia was higher than that from fruit bodies, but protein content was vice versa. Extracts of the cultured mycelia were more effective and lasting than extracts of the fruit bodies in decreased hypertention of spontaneously hypertensive rats (SHR).

• Food Science and Preservation
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• v.24 no.1
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• pp.60-67
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• 2017

In this study, we tried to establish the best method for fresh blueberry beverage production using enzyme treatment as well as low temperature extraction. During extraction of physiologically functional materials, we used low temperature to prevent nutritional loss by heat. In addition, we investigated optimal blueberry extraction conditions using various enzyme treatments (cellulase, pectinase, cellulase:pectinase (1:1) mixture) to increase extraction efficiency and reduce turbidity. A variety and ratio of enzymes, extraction temperature, extraction time, and shaking speed were considered for the best extraction efficiency rate. We observed high extraction efficiency rates of 85.72-86.55% and 87.06-87.93%, respectively, upon cellulase or pectinase treatment. In addition, a mixture of cellulase:pectinase (1:1) showed an extraction efficiency rate of 86.84-88.14%. The best extraction efficiency rate was observed when crude blueberry was treated at $45^{\circ}C$ (87.91%), for 3 h (87.88%), in a 90 rpm shaker (89.19%). Sugar content and acidity of blueberry extract were not affected by the various treatments. However, total phenolic compounds were detected upon pectinase treatment (18.62 mg/g). Only fructose and glucose as free sugars were found in all samples regardless of treatments and extraction conditions.

• Journal of Korean Society of Transportation
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• v.21 no.4
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• pp.67-77
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• 2003

The purpose of this study is to provide the criteria for implementing unprotected left turn at intersections with variation of traffic volume on a cross road approach. Using Transyt-7F model, the delays calculated from permissive and protected left turn signal system were compared by gradually increasing the left turn volume for a certain opposing through volume up to the volume limits to which permissive left turn is more effective, Average stopped delay of the intersection was used as the measure of effectiveness in this study. The major conclusions are (1) the lighter the traffic gets in a cross road, the more the allowable left turn volume increases. The allowable left turn volume when the ratio of cross traffic to the concerned approach traffic is 0.6 appears about 50% more than the volume when the ratio is 1.0. (2) Comparing to the criteria of the manual of traffic safety facility, the results when the traffic ratio is 0.6 seem to be most similar the criteria of manual and the results when the traffic ratio are 0.8 and 1.0 appears to be lower than the criteria of manual. (3) The possible amount of making a left turn that is inversely proportional to the opposing through traffic, decreases as the number of opposing through lanes increases. The products of volume need to be used as the criteria of permissive left turn with considerable cautions because of its low consistency.

• Food Engineering Progress
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• v.13 no.1
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• pp.56-63
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• 2009

The aim of this study was to control the outbreak of food pathogen through quantitative microbial risk assessment (QMRA). We used Monte Calro Simulation (MCS) to predict contamination levels of Staphylococcus aureus on the raw materials, equipments and cook in Japanese restaurant located in Seoul. The result of sensitivity analysis showed that the most significant factor for the outbreak of food pathogen was consumption temperature and storage time. In shrimp and octopus sushi, 'consumption temperature' was the highest sensitivity value of 0.419 followed by 'storage time' of 0.374. To increase safety of sushi, consumers should have sushi as soon as possible after cooking. In sushi 'storage time after cooking' was determined as Critical Control Point (CCP). To determine Control Limit (CL), Scenario Analysis (SA) was carried out. In sushi, SA was carried out using storage time as a unit condition. Safety level of S. aureus was set lower than 5 log CFU/g. After 2 hr 'storage time' the number of S. aureus increased to 3.908 log CFU/g. Therefore, 'storage time' of sushi was set as CL in case of room temperature storage.

• The Journal of the Korea Contents Association
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• v.21 no.3
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• pp.567-575
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• 2021

Residents in Dangjin, South Chungcheong Province, in which large-scale emissions facilities such as coal-fired power plants and steel mills are concentrated, are very much concerned about their health despite the local government's aggressive efforts to improve air quality and reduce greenhouse gases. To understand the impact of coal-fired power plants and external factors on local air pollution, the origins of local pollutants were investigated using stable carbon isotopes that are generally used as tracers of the provenance of fine or ultrafine dust. The origins of the pollutants were analyzed with the data library, built using the seasonally measured data for the two separate locations selected considering the distance from the coal-fired power plant and the analysis of previous studies, and with the back trajectory analysis. As a result of analyzing stable isotope ratios, the tendency of high concentration was found in the order of winter > spring > fall > summer. According to the data matching with the library, the mobile pollutants and open-air incineration had a relatively higher impact on the local air pollution. It is believed that this study, as a pilot study, should focus on securing the reliability of the study results through continuous monitoring and data accumulation.

• Journal of Practical Agriculture & Fisheries Research
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• v.22 no.1
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• pp.43-53
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• 2020

The test conducted in this study was carried out for three years from 2013 to 2015 to investigate the optimal level of seeding amount and nitrogen fertilizer application to cultivate and produce the seeds of rye in Jangsu province, Jeollabuk-do. The variety of forage rye used in this experiment was 'Gogu', developed by National Institute of Crop Science, Suwon, Korea in 2004. The seeding rate was four levels (3, 5, 7 and 9 kg 10a^-1, respectively) while nitrogen fertilized with respective amounts of 0, 3, 6, and 9 kg 10a^-1. In Jangsu, the number of spike per m² and lodging ratio were increasing, while fertility rate, 1 liter weight, 1000-grain weight and seed productivity were decreased by increasing of seeding rate from 3 kg 10a^-1 to 9 kg 10a^-1. There was an increase in the number of spike per m², culm lengh, the number of grain per spike, lodging ratio and seed productivity, while productiove tiller, 1 grain weight, and 1 liter weight were decreased by increasing nitrogen fertilizer level from 3kg 10a^-1 to 9 kg 10a^-1. The best seeding rate and nitrogen fertilizer level for rye seed production were 5 kg and 6 kg 10a^-1, respectively, considering plant lodging, seed and fertilizer reduction and the prevention of pollution by excess fertilization.

• Land and Housing Review
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• v.13 no.3
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• pp.93-106
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• 2022

Ventilation plays an important role in controlling indoor air quality. Due to the recent spread of infectious diseases such as COVID-19 and with people spending more time indoors, there's been increased attention on the importance of ventilation performance. In many countries, ventilation is regulated by airflow rates and the number of air changes per hour (ACH). However, airflow rates and ACH alone do not provide an accurate account of actual indoor pollutant removal and ventilation uniformity in a space. This study looked into the ventilation performance of an actual residential unit using several sampling points instead of basing it off of airflow and air change rates. Literature review was used to derive relevant influencing factors and the tracer gas dilution method was used for the field test. The study measured air velocity, age of air, and ventilation efficiency at several locations and compared them to the average value at the center of the test space to determine the differences in ventilation performance at the selected measurement points. The study showed that different sampling locations resulted in different ventilation values. Findings of this study will be used to develop an experimental procedure for evaluating indoor ventilation performance of actual residential spaces.

• Journal of Korean Historical Folklife
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• no.45
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• pp.291-325
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• 2014

This study is about examining the changing process of worshiping heaven in the end of the Koryo dynasty and early Chosun dynasty. For this, it was compared with book of national rites. This paper will outline the differences of commemorative rites of worshiping heaven between Korea and China and its reason for changing process. Also, it shows the understanding of the historic characteristics of commemorative rites of worshiping heaven in the end of the Koryo dynasty and early Chosun dynasty through analyzing conducted religious service. Following methodological approach was used to achieve the aim of the study. The study includes historical changing process and basic ritual of commemorative rites of worshiping heaven from Koryo dynasaty to King Sejo period through various chronicles and books of rites. Understanding the trend transition of operating commemorative rites of worshiping heaven is expressed differently based on the situation in those days even though it is the same operation of commemorative rites of worshiping heaven. The existing study only primarily considered the rites of worshiping heaven in the end of the Koryo dynasty and early Chosun dynasty through the resources within the country. However, the process of settlement of commemorative rites of worshiping heaven is closely related to settlement of Confucian formality. As the problems cannot be solved if institutional changes are researched only though the resources within the nation, this following study also considered the transition of commemorative rites of worshiping heaven in China for sure. Through this approach, the study understood how China's rites of worshiping heaven settled down and formed in Korea and found differences of the rites of worshiping heaven between the two nations by comparing China's book with ornamental "seal" characters throughout many generations. Furthermore, it also illustrated historical characteristics of rites of worshiping heaven in the end of the Koryo dynasty and early Chosun dynasty by analyzing carried out religious service. Although it seems like there are many similarities of Chinese ritual procedure between Koryo dynasty and Chosun dynasty, there are existing significant differences in the context. Moreover, it is clear that there are differences of ritual between Tang, Song, Ming dynasty. These differences are directly connected to Korea and also with transition of king's power. Generally, Tang and Song dynasty show similar trend whilst Ming clarifies the differences between the two. For instance, there are differences between deep bow and superintendent of cho-hun, a-hun, and jong-hun. Transition of configuration is also one of the major differences. Changing of configuration has considerably important meaning refer to status of king's power. Analyzing specific features, such as size of altar, ancestral tablet, people who participate in sacrifices, okpye, configuration, and etc., made possible to consider the actual differences, not just examining different features of vaguely. Based on this foundation, the study closely examined the differences among the periods between the nations and gave the significance of the differences.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.13 no.1
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• pp.1-10
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• 2015

In the safety assessment of the geological disposal system of the radioactive wastes, the abnormal scenarios, in which the system is impacted by the abnormal events, need to be considered in addition to the reference scenario. In this study, characterization and prediction of well intrusion as one of the abnormal events which will impact the disposal system were conducted probabilistically and statistically for the safety assessment. The domestic well development data were analyzed, and the prediction methodologies of the well intrusion were suggested with a computation example. From the results, the annual well development rate per unit area in Korea was about 0.8 well/yr/km² in the conservative point of view. Considering the area of the overall disposal system which is about 1.5 km², the annual well development rate within the disposal system could be 1.2 well/yr. That is, it could be expected that more than one well would be installed within the disposal system every year after the institutional management period. From the statistical analysis, the probabilistic distribution of the well depth followed the log-normal distribution with 3.0363 m of mean value and 1.1467 m of standard deviation. This study will be followed by the study about the impacts of the well intrusion on the geological disposal system, and the both studies will contribute to the increased reliability of safety assessment.