• Title/Summary/Keyword: 경증

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A Clinical Observation on Childhood Shigellosis Occurred in Mass Outbreak (소아에서 집단 발병한 세균성 이질의 임상적 고찰)

  • Lee, Soo-Jin;Yu, Young;Kim, Sin-Na
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.5 no.1
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    • pp.33-38
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    • 2002
  • Purpose: The incidence of shigellosis had been decreased due to the use of antibiotics and the improvement of environmental sanitation but recently increases again. Shigellosis occurrs in mass outbreak through unsanitized meal preperation refered from welfare facility and school. We observed epidemic aspect and clinical coarse of childhood shigellosis. Methods: from December 2001 to January 2002, 22 inpatients with shigellosis in Dongbu Municipal Hospital were observed epidemiologically, clinically and microbiologically. Results: 1. The sexual ratio was 1:1 and mean age was $5.5{\pm}1.4$ years (14 months to 11 years). 2. The clinical manifestations were following: diarrhea (95.5%), high feve (10%) and asymptomatic (4.5%). The mean duration was $3.9{\pm}2.1$ days (1 to 12 days). All patients had no complication and normal serologic test. 3. S. sonnei was cultured in rectal swab, and was resistant to TMP/SMX and ampicillin, but susceptible to ampicillin/sulbactam and the 3rd generation cephalosporins. 4. The patients were treated by antibiotics with conservative treatment including electrolytes and fluid therapy for 5 days, resulting in improvement confirmed by negative reaction on stool culture. 5. These cases were all occurred in mass outbreak in day care center and were suspected to be secondary infection by members of family. Conclusion: This shigellosis occurred in day care center was secondary infection due to S. sonnei and had mild clinical coarse and improvement after antibiotic treatment.

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Immunotoxicity Study of Separated Antigen from Helicobacter pylori. (Helicobacter pylori로부터 유래된 항원의 항원성에 관한 연구)

  • Park, Chang-Ho;Bae, Man-Jong
    • Journal of Life Science
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    • v.18 no.4
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    • pp.494-502
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    • 2008
  • The anaphylaxis shock reaction on the whole cells of H. pylori exhibited a symptom of slight illness for the first and second medication of causing antigen at an antigen concentration of WC (H) $60\;{\mu}g/100\;{\mu}l$ for WC (H) and no anaphylaxis shock symptom was observed at an antigen concentration of $20\;{\mu}g/100\;{\mu}l$ for WC (L). In the case of anaphylaxis shock reaction on the crude urease, no symptom was observed at an antigen concentration of $20\;{\mu}g/100\;{\mu}l$ for both urease (L) and urease (H). In the heterologous passive cutaneous anaphylaxis (PCA) test using a guinea pig-rat, no positive reaction was detected in all the medication groups of WC (H), WC (L), urease (H) and urease (L). In the skin sensitization test, it was observed that the best antigen concentration not causing skin disorder at each of $80\;{\mu}g/100\;{\mu}l$, $40\;{\mu}g/100\;{\mu}l$, $20\;{\mu}g/100\;{\mu}l$, and $20\;{\mu}g/100\;{\mu}l$ was $40\;{\mu}g/100\;{\mu}l$.

Satisfaction and Experience of the Elderly with Dementia for the Service Provided by the Dementia Day Care Center (치매주간보호센터에서 제공하는 서비스에 대한 치매노인의 만족도와 경험)

  • Kim, Hwasoon;Lee, Young-Whee;Jung, Da-Woe;Lee, Jee-Yeon
    • The Journal of the Korea Contents Association
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    • v.19 no.7
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    • pp.609-627
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    • 2019
  • The purpose of this study was to explore service satisfaction of the elderly using dementia day care center and the meaning of day care experience. The subjects for this methodological triangulation study were 67 dementia elderly for 1:1 interview and 15 dementia elderly for focus group interview. All subjects were using dementia day care center. The mean age was $79.95{\pm}5.90$ for quantitative study and $80.07{\pm}5.78$ for qualitative study subjects. The mean scores of service satisfaction were ranged from $2.86{\pm}0.41$ to $2.96{\pm}0.30$. The lowest score domain was 'help and assistance', and the highest score domain was 'food and environment'. In 14 questions, satisfaction score was 3 point. According to content analysis, the experiences of dementia day care center were described with 20 themes such as 'mutual respect and understanding', 'pleasure and upset feelings about participation', etc. and 35 sub-themes. The overall satisfaction scores were high and in most cases the positive experiences with dementia day care service were described. Therefore it is recommended for mild dementia elderly to use dementia day care service and to be expanded.

Characters and Factors Affecting the Life Satisfaction of the Older Adults with Disabilities: A Comparison of one-person and multi-person households (고령장애인 실태와 생활만족도 영향 요인: 1인가구와 다인가구 비교)

  • Park, Ju-Young
    • The Journal of the Korea Contents Association
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    • v.18 no.12
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    • pp.272-280
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    • 2018
  • The purpose of this study was to analyze characters and determinant factors of the life satisfaction of the older adults with disabilities so as to provide suggestion for improving the quality of life. I used the data on 8th Panel Survey of Employment for the Disabled(PSED). The total number of respondents was 452, 126 respondents of one-person households and 326 respondents of multi-person households. The data was analyzed using SPSS Win 24.0 program and utilizing $x^2$test, ANOVA, logistic regression analysis. First, The characteristics of older adults with disabilities was man, married, mild disorder, physical external disorder, non-basis living security recipient, unemployment and the level of life satisfaction was 3.27. Second, The one-person households group showed female, non-married, severe disorder, lower acceptance of disability, lower health status, higher help daily living activity, higher discrimination experience, unemployment, lower income, basis living security recipient, lower position than multi-person group. Third, acceptance of disability, health status, social activity, religion were found to have a significant effect on the life satisfaction of one-person households. And acceptance of disability, health status, position were found to have a significant effect on the life satisfaction of multi-person households. Base on the results of this study, suggested for improving the quality of life of the older adults with disabilities.

Factors Affecting on the Unemployment Hazard Rate of the People with Disabilities (장애인의 실업탈출 결정요인에 관한 연구)

  • Nam, Jeong Hwi;Choi, Young
    • 재활복지
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    • v.17 no.4
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    • pp.127-149
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    • 2013
  • This study analyzed the hazard of unemployment and the influencing factors on the rate. Data came from the Panel Survey of Employment for the Disabled(PSED), 2010-2012, which is a longitudinal survey for 5,092 disabled people in Korea. For the main purpose of this study, the life-table method was used for describing the patterns of unemployment duration by disabled, and the cox proportional hazard model was used to identify significant factors on the unemployment duration. The results were as follows. First, according to the life table analysis, the unemployment rate to remain until the longest period of unemployment(25month) is 90.5%, and the rate of entry into the labor market was only 9.5%. Overall, the unemployment maintenance rate was high, the unemployment escape rate decreased after 12month. Second, looking at the results from the cox proportional hazards model, the unemployment escape possibility were increased for those who are male, are non-public benefit recipient with disability, have mild disability, and have less discrimination experiences. With these results, disability discrimination act which can reduce the disability discrimination in employment site should be strengthened. Also, the scheme of Nation Basic Protection Program should be modified to attract the employment of recipients with disability. Finally, policy targets having employment escape difficulty, such as women with disability, people with severe disabilities should be departmentalized. And employment service is provided in accord with the individual needs and characteristics.

Clinical Usefulness of Ultrasonography in the Diagnosis of Fatty Liver (지방간 진단에 있어 초음파 검사의 임상적 유용성 연구)

  • An, Hyun;Lee, Hyo Yeong
    • Journal of the Korean Society of Radiology
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    • v.13 no.3
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    • pp.349-357
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    • 2019
  • The purpose of this study was to evaluate the clinical significance of ultrasonographic classification of fatty liver in three grades. From June 2018 to April 2019, 1047 patients (818 males and 229 females) diagnosed as fatty liver among 3607 patients who underwent abdominal ultrasonography at Busan screening center. Ultrasonography was classified into three grades: Grade I (mild fatty liver), Grade II (moderate fatty liver), and Grade III (severe fatty liver) according to the degree of parenchyma texture, acoustic attenuation, Obesity index, hematological test, and metabolic syndrome. The average age of men in each sex increased with the increase of the fatty liver. Body mass index (BMI) and waist circumference were significantly increased in both men and women (p=.000). hematological analysis showed that AST, ALT, ${\gamma}-GTP$, TG, fasting blood sugar, and glycated hemoglobin were significantly different from each other (p<.05). In women, ALT, ${\gamma}-GTP$ and TG showed a significant difference with increasing fatty liver (p<.05). The prevalence of metabolic syndrome was significantly increased in both sexes as the grade of fatty liver increased (p=.000). Based on the results of this study, it is suggested that the use of ultrasound - guided fatty liver according to severity may be useful for the treatment and follow - up of fatty liver if the liver grade is divided in consideration of hematological variables and metabolic syndrome.

The characteristics of mild head injuries in preschool-age children fall: a retrospective observational study (학령전기 소아에서 추락으로 인한 경증 두부손상의 특징에 대한 후향적 관찰 연구)

  • Sung, Min Suk;Lee, Ji Sook;Jeon, Woochan;Park, Junseok;Kim, Kyung Hwan;Shin, Dongwun;Kim, Hoon;Park, Joon Min;Kim, Hyunjong
    • Journal of The Korean Society of Emergency Medicine
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    • v.29 no.5
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    • pp.423-429
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    • 2018
  • Objective: Falling is a common cause of head injury in preschool aged children. We investigated the characteristics of mild head injuries caused by falling and the association between body weight and occurrence of traumatic brain injuries (TBI). Methods: This retrospective observational study was conducted on head-injured preschool-aged children that visited the emergency department from January 2012 to December 2015. Characteristics such as age, sex, weight, free fall height, floor type, and presence of TBI, as defined as cerebral hemorrhage or skull fracture, were investigated. We calculated body weight percentiles by calibrating age and weight and categorized them into four quartile ranges. We grouped all included cases into two groups according to the presence of TBI. The characteristics of the two groups were compared by using chi-square test, and the association with TBI was investigated by using binomial logistic regression. Results: A total of 701 children were included, and TBI was observed in 95 children. Children with TBI were younger. The proportion of children with TBI was higher in the third and fourth quartiles of the body weight group as well as according to soft floor and fall from high height (${\geq}1m$). The odds of soft floor being associated with TBI was higher than the odds for hard floor (odds ratio, 2.734; 95% confidence interval [CI], 1.597-4.680). The odds of high height (${\geq}1m$) being associated with TBI was higher than that for low height (odds ratio, 2.306; 95% CI, 1.155-4.601), and the odds ratio for the weight percentile group was 1.228 (95% CI, 1.005-1.499). Conclusion: Prevalence of TBI after falling in preschool-aged children might be associated with high fall-height and body weight quartiles.

Relationship between usage of removable denture and depression in Korean adults with loss of multiple teeth: A cross-sectional study using the seventh Korea National Health and Nutrition Examination Survey (다수 치아를 상실한 한국 성인에서 가철성 의치의 장착 여부와 우울증의 연관성: 국민건강영양조사 제 7기 자료를 활용한 단면 연구)

  • Shim, Jaeseung;Lee, Younghoo;Hong, Seoung-Jin;Noh, Kwantae;Pae, Ahran;Kim, Hyeong-Seob;Kwon, Kung-Rock;Paek, Janghyun
    • The Journal of Korean Academy of Prosthodontics
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    • v.59 no.1
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    • pp.1-10
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    • 2021
  • Purpose: The purpose of this study is to evaluate the relationship between removable denture and depression. This study aims to investigate the relationship between depression and each group by dividing them into a group that were using removable dentures and a group that needed removable dentures but were not using removable dentures. Materials and methods: This study was conducted using raw data from the 7th Korea National Health and Nutrition Examination Survey (KNHNES). By using variables related to the state of the prosthesis and the need for prosthesis among oral examination data, the oral examination data were classified into two groups; group using removable denture and group in need of removable dentures. In addition, the variables of depression were classified into normal (0-4), mild depression (5-9), moderate depression (10-19), and severe depression (20-27) using the values of PHQ-9. For statistical analysis, logistic regression analysis was performed using SAS 9.4. Results: In the group in need of removable dentures, the risk of severe depression was statistically and significantly higher than the group using removable dentures. Conclusion: In patient who have lost multiple teeth, rehabilitation of the missing area with removable dental prosthesis is expected to decrease the occurrence of severe depression.

The Effects of Ecklonia stolonifera Extracts on Improvement of Hepatic Function: a Double-Blind, Randomized, Placebo-Controlled Clinical Study (곰피추출물의 간기능 개선 효과 평가를 위한 12주, 무작위배정, 이중맹검, 위약-대조 인체적용시험)

  • Kim, Junghee;Kim, Eun Jin;Kang, Dahye;Kim, Hyung-Bin;Jang, Jae Young;Om, Ae-Son;Kim, Jongwook
    • Journal of Food Hygiene and Safety
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    • v.37 no.3
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    • pp.198-205
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    • 2022
  • Hepatic diseases are divided into two types: alcoholic and non-alcoholic. Non-alcoholic liver injury finally induces fatty liver and damages liver function. Many studies have demonstrated that Ecklonia stolonifera has antioxidative, anti-inflammatory, and hepatoprotective activities. We conducted a 12-week double-blind, placebo-controlled, randomized trial to examine the efficacy of E. stolonifera extracts (ESE) on biochemical markers of hepatic function. Sixty-five subjects with mild or moderate liver injuries were randomly allocated to receive either 420 mg/d of ESE or a placebo for 12 weeks. Fifty-five participants completed the trial. No significant adverse events were observed among the subjects during the study. The primary end points were changes in plasma levels of aspartate transaminase (AST), alanine transaminase (ALT), and γ-glutamyltransferase (γ-GT). The secondary end points were changes in lipid profile levels, including total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL), and low-density lipoprotein cholesterol (LDL). Compared with the baseline, AST and ALT levels decreased significantly in the ESE group compared to those in the placebo group (P<0.001). In addition, γ-GT levels in the ESE group were significantly lower than those in the placebo group (P=0.016). There were no differences in the TC, TG, HDL, and LDL levels between groups. In conclusion, ESE consumption for 12 weeks improved liver parameters in subjects with liver injury. Regular consumption of ESE could maintain liver health in individuals at risk of hepatic damage.

Development of community-based intensive health care program for the community dwelling elderly (재가노인을 위한 지역사회 중심의 집중건강관리프로그램의 개발과 적용)

  • Song, Mi-Sook;Song, Hyun Jong
    • 한국노년학
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    • v.29 no.1
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    • pp.37-50
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    • 2009
  • The purpose of the present study was to develop a community-based intensive health care program for the community dwelling elderly to strength their functional status and to verify the effect on their geriatric syndrome. A one-group pretest-posttest design was used for the study. A total of 69 frail elderly, who lived in the area within 20 minutes by car, were committed themselves to the day care center(Sangikjae), and had the ability of verbal communication were selected from G city in Kyunggi province. The participants completed a set of questionnaires to measure the sub-score of frailty, fall, urinary incontinence, malnutrition, and mild cognitive disorder domain, using the Otasha-Kensin through the physical examinations and interviews. After 4 weeks of intervention, the outcome was measured to evaluate the effects of the program, and the data obtained were analyzed using descriptive statistics, paired t-test and McNemar test. The results showed that the sub-score of frailty, fall, urinary incontinence, and malnutrition domain were statistically significantly decreased after intervention except those of urinary incontinence and mild cognitive disorder domain, implying that the risk of frailty, fall, and malnutrition was decreased. These findings indicated that community-based the intensive health care program is effective for relieving geriatric syndrome of the community dwelling elderly.