• Journal of the Society of Cosmetic Scientists of Korea
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• v.40 no.2
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• pp.179-186
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• 2014

This study was performed to DPPH radical scavenging activity, ABTS radical scavenging activity, tyrosinase inhibition activity and intracellular melanin synthesis inhibition to verify the whitening effect of Fagopyrum tataricum (bitter buckwheat) extract as contrasted with Fagopyrum esculentum (sweet buckwheat) extract. F. tataricum extract in consequence showed higher antioxidant activities, tyrosinase inhibition activity and melanin synthesis inhibition compared with F. esculentum extract. We investigated skin bright value during 8 weeks after induction of pigmentation in human skin from UV irradiation. In result, we obtained statistically a significant skin whitening effect from visual and mechanical evaluation. Accordingly, F. tataricum extract is expected to be high availability as functional cosmetic material for skin whitening.

• Proceedings of the IEEK Conference
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• 2001.09a
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• pp.407-410
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• 2001

최근 영상 검색(retrieval)과 분류(classification)에서 질감 특징(texture feature)을 이용한 연구들이 활발하게 진행되고 있다. 본 논문에서는 효율적인 질감 특징 추출을 위해 명암도 상호발생 행렬법(gray level co-occurrence matrix)과 웨이블릿 변환(wavelet transform)을 이용하여 질감의 특징을 추출한 후 특징의 중요도에 따라서 가중치를 부여하는 방법을 제안한다. 이렇게 추출된 가중치 대표 벡터들을 기반으로 베이시안 분류기(Bayesian classifier)를 통해 임의의 질감을 인식하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04b
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• pp.697-699
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• 2004

LCD의 생산이 많아짐에 따라 LCD의 불량 검출이 중요해 지고 있다. 불랑 검사는 눈으로 확인할 수 있는 범위에서 검사가 이루어지고 있으며, 만약 눈으로 식별이 불가능한 경우 적외선 카메라나 초음파 센서를 사용하여 검사가 이루어진다. 본 논문에서는 카메라를 이용하여 LCD 패널의 표면에 있는 불량 검출을 위하여 각 Dot에 대한 R, G, B 값을 추출한 후, 추출된 픽셀을 제안된 알고리즘에 적용하여 불량을 검출하는 것을 목적으로 하고 있다.

• Journal of Plant Biotechnology
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• v.46 no.1
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• pp.45-55
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• 2019

TheCitrus grandis Osbeck is a special product in the Jeju island. The product has been as a remedy for liver damage and hang over. This study demonstrates how to investigate and compare the antioxidant, phenol content, tyrosinase and ${\alpha}$-glucosidase inhibitory activity, antimicrobial, and alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activity with the C. grandis leaves extracted in different ethanol concentrations. From the yield, a 20% ethanol extract demonstrated the highest results among the other extracts. The distilled water extract showed the most abundant in a total phenol content and highest ABTS radical scavenging activity and reducing power assay. In the DPPH radical scavenging activity, ${\alpha}$-glucosidase and tyrosinase inhibitory assay (used ${\text\tiny{L}}$-tyrosine as substrate), the 80% ethanol extract exhibited a higher value than other extracts. The 60% ethanol extract showed prominent activities in the tyrosinase inhibitory (used ${\text\tiny{L}}$-dopa as substrate), ADH and ALDH activity assay. In the minimum inhibitory concentration (MIC) assay, 60% and 80% ethanol extracts inhibited the bacterial growth almost similarly. Moreover, the gram-positive bacteria was more restrained than the gram-negative bacteria. The resultsrevealed that the distilled water and 80% ethanol extract showed a relatively higher antioxidant activity compared to other extracts. The 60 ~ 80% ethanol extracts demonstrated potential tyrosinase, ${\alpha}$-glucosidase inhibitory, antimicrobial, ADH and ALDH activities. Therefore, the C. grandis is suggested to be considered as a functional material for various proposes.

• Journal of KIISE:Databases
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• v.30 no.6
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• pp.573-584
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• 2003

Recent massive data generation by genomics and proteomics requires bioinformatic tools to extract the biological meaning from the massive results. Here we introduce ROSPath, a database system to deal with information on reactive oxygen species (ROS)-mediated cell signaling pathways. It provides a structured repository for handling pathway related data and tools for querying, displaying, and analyzing pathways. ROSPath data model provides the extensibility for representing incomplete knowledge and the accessibility for linking the existing biochemical databases via the Internet. For flexibility and efficient retrieval, hierarchically structured data model is defined by using the object-oriented model. There are two major data types in ROSPath data model: ‘bio entity’ and ‘interaction’. Bio entity represents a single biochemical entity: a protein or protein state involved in ROS cell-signaling pathways. Interaction, characterized by a list of inputs and outputs, describes various types of relationship among bio entities. Typical interactions are protein state transitions, chemical reactions, and protein-protein interactions. A complex network can be constructed from ROSPath data model and thus provides a foundation for describing and analyzing various biochemical processes.

• The Journal of the Korea Contents Association
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• v.5 no.6
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• pp.31-40
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• 2005

In the post-genomic era, researches on proteins as well as genes have been increasingly required. Particularly, work on protein-protein interaction and protein network construction have been recently establishing. Most biologists publish their research results through papers or other media. However, biologists do not use the information effectively, because the published research results are very large. As the growth of internet field, it becomes easy to access these research results. It is important to extract information with a biological meaning from various media. Therefore, In this paper, we efficiently extract the protein information from many open papers or other media and construct the database of the extracted information. We build a protein network from the established database and then design and implement various pathway analysis algorithms which find biological meaning from the protein network.

• Proceedings of the Korean Information Science Society Conference
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• 2002.10d
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• pp.148-150
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• 2002

본 논문은 모바일 핸드셋이라는 제한적인 디스플레이 환경과 입력환경에서 필요한 라우트맵의 시각화에 따른 문제점과 그 해결방안을 제시한 논문이다. 자동차 네비게이션 시스템에서 널리 사용되는 경로표시 방법은 일반적으로 노트북이나, PDA, 전용 디스플레이 시스템등에서 구현되어 있으나, 모바일 핸드셋과 같이 제한된 디스플레이 환경에서의 경로표시 방법은 현재까지 많은 연구가 이루어지지 않고 있다. 본 논문은 인간의 인식능력이 임의의 경로를 회전방향점(turning point)의 연속으로 인식한다는 점에 착안하여 원래의 경로가 가진 축적을 변형하여 선분과 회전방향점으로 경로를 표시하는 라인 드라이브 시스템을 모바일 환경의 경로표시 방법으로 사용하였다. 본 논문에서 구현한 시스템은 GIS의 벡터 정보를 가지고 있는 서버와 Brew 플랫폼을 지원하는 모바일 핸드셋으로 구성된다. GIS 서버는 프로토타입 정보를 추출하여 모바일 핸드셋으로 전송하고, 이러한 정보는 모바일 핸드셋의 Brew 플랫폼에서 간략화, 도식화 과정을 거쳐서 시각화된다. 본 논문은 제한된 디스플레이 환경의 경로 확대표시를 위하여 계층별 경로 시각화 방법을 사용하여 가독성을 높이고 사용상의 편리함을 추구한다.

• Journal of Korea Multimedia Society
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• v.13 no.7
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• pp.1044-1050
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• 2010

Endoscopic ultrasonography is a medical procedure in endoscopy combined with ultrasound to obtain images of the internal organs. It is useful to have a predictive pathological manifestation since a doctor can observe tumors under mucosa. However, it is often subjective to judge the degree of malignant degeneration of tumors. Thus, in this paper, we propose a feature analysis procedure to make the pathological manifestation more objective so as to improve the accuracy and recall of the diagnosis. In the process, we extract the ultrasound region from the image obtained by endoscopic ultrasonography. It is necessary to standardize the intensity of this region with the intensity of water region as a base since frequently found small intensity difference is only to be inefficient in the analysis. Then, we analyze the spot region with high echo and calcium deposited region by applying LVQ algorithm and bit plane partitioning procedure to tumor regions selected by medical expert. For detailed analysis, features such as intensity value, intensity information included within two random points chosen by medical expert in tumor region, and the slant of outline of tumor region in order to decide the degree of malignant degeneration. Such procedure is proven to be helpful for medical experts in tumor analysis.

• Journal of agriculture & life science
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• v.45 no.5
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• pp.73-80
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• 2011

Fifty substances of pesticide were selected for analysis through the historical investigation of pesticides detected from environmental-friendly agricultural soil, and the environmental-friendly agricultural soils in Gyeongnam area were collected and then were accepted Anve (accelerated solvent extraction) and SPve (solid-phase extraction) as multiresidue extraction and clean up methods suitable to the soils. The pesticide residues were analyzed by using GC/vCD/NPD, HPLC/UV/FL, GC/MSD, or HPLC/MSD. 50 kinds of pesticides for the soils were an average of 95.5% from retrieval ratio of the 72 to 118% range, and the average of 3.0% for CV (%). Among 40 samples of soil, 20 components were detected from pesticide residues of 21 samples, and average amounts detected for these components were 0.035 for endosulfan, 0.043 for ethoprophos, 0.020 for chlorpyrifos, 0.023 for chlorfenapyr, 0.047 for flufenoxuron, 0.070 for fenvalerate, 0.266 for cypermethrin, 0.016 for lufenuron, 0.022 for bifenthrin, 0.025 for fenobucarb/BPMC, 0.043 for difenoconazole, 0.059 for fenarimol, 0.020 for kresoxim-methyl, 0.026 for tetraconazole, 0.039 for isoprothiolane, 0.017 for iprobenfos, 0.014 for nolrimol, 0.156 for fluquinconazole, 0.047 for tebuconazole, and 0.045 mg/kg for oxadiazon. Therefore it is infered that the establishment of pesticide residues limit for environmental-friendly agricultural soil is needed as soon as possible.

• Journal of the Korean Society of Food Science and Nutrition
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• v.29 no.3
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• pp.537-542
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• 2000

감잎추출물이 고콜레스테롤혈증에 미치는 영향을 구명하고자 흰쥐에게 1% 콜레스테롤과 0.25% 콜산나트륨을 첨가한 고폴레스테롤혈증 유발 식이와 감잎추출물을 1, II수준(126 mg or 252 mg/kg body weight)으로 나누어 경구투어하여 녹차추출물 (126 mg/kg body weight)과 비교.검토하였다. 혈청과 간조직의 중성지질 농도는 녹차추출물군에서 가장 낮은 반면 총, 유리, 콜레스테릴에스테르 농도는 녹차추출물군에 비하여 감잎추출물 I군의 감소 정도가 큰 것으로 나타났다. 킬로미크론, LDL콜레스테롤 농도 역시 감이ㅠ추출물 투여로 현저하게 감소하였으며, II수준에 비하여 I 수준에서 그 효과가 우수한 것으로 관찰되었다. VLDL-콜레스테롤 농도는 감잎, II군이 감잎 1군에 비하여 유의적으로 감소되었다. 반면, HDL-콜레스테롤 농도와 HDL-C/TC비는 감잎추출물 I군이 녹차추출물군과 감잎추출물 II군에 비하여 유의적으로 증가하였으나, 동맥경화지수는 감소하였다. 총콜레스테롤, VLDL-과 LDL-콜레스테롤의 농도 증가는 관상 동맥질환의 위험요소인데, 특히 감잎추출물 투여시 이들 콜레스테롤 농도 감소가 현저하므로 고콜레스테롤 혈증 흰쥐의 지질대사 개선효능을 알 수 있었다.