• Korean Journal of Acupuncture
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• v.38 no.1
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• pp.32-42
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• 2021

Objectives : In this study, we investigated the neuroprotective effects of ethanol extract of Lonicera japonica flower buds (EELJ) on glutamate-induced neurotoxicity in mouse hippocampus-derived neuronal HT22 cells. Methods : After analyzing the cytoprotective effect of EELJ on glutamate in HT22 cells, the inhibitory effect of apoptosis was studied using flow cytometry. In order to analyze the antioxidant efficacy of EELJ, the levels of reactive oxygen species (ROS) and glutathione (GSH) were investigated, and the effects on the activities of superoxide dismutase (SOD) and catalase (CAT) were also analyzed. Furthermore, the effect of EELJ on the expression of apoptosis regulators such as Bax and Bcl-2 in glutamate-treated HT22 cells was investigated. Results : According the current results, pretreatment with EELJ significantly reduced glutamate-induced loss of cell viability and release of lactate dehydrogenase. EELJ also markedly attenuated glutamate-induced generation of intracellular ROS, which was associated with increased levels of GSH, and activity of SOD and CAT in glutamate-stimulated HT22 cells. In addition, EELJ was strikingly inhibited glutamate-induced apoptosis in HT22 cells. Furthermore, the expression of pro-apoptotic Bax was increased and the expression of anti-apoptotic Bcl-2 was decreased in glutamate-treated HT22 cells, while in the presence of EELJ, their expressions were maintained at the control levels. Conclusions : These findings indicate that EELJ protects glutamate-induced cytotoxicity in HT22 hippocampal neurons through antioxidant activity. Therefore, although identification of biologically active substances of EELJ and re-evaluation through animal experiments is necessary, this natural substance is a promising candidate for further research in preventing and treating oxidative stress-mediated neurodegenerative diseases.

• Korean Journal of Oriental Medicine
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• v.1 no.1
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• pp.363-400
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• 1995

The electroacupuncture according to Voll(EAV) is a method of combining the fundamentals of classical acupuncture with the facilities of modern electronics for diagnostics and therapy. Classical acupuncture uses energy conducting lines called 'meridians' and acupuncture points situated along them. Dr. Voll is considered the founder of 'EAV' since he succeeded not only in finding a method of exact electric localization and in explaining the interelation between the acupuncture points and their individual organs, but he also succeeded in measuring the resistance of these points and in explaining the diagnostic meaning of the measured values. In the course of his research, Voll found numerous new measurement points and energy conducting vessels unknown to classical acupuncture, but indispensible for diagnosis of human organic functions. As a basis of modern research in meridian theory, I tried to compare EAV measurement point with classical acupuncture point.

• The Journal of Dong Guk Oriental Medicine
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• v.7 no.2
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• pp.1-8
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• 1999

This paper documents a holistic study of the kidney and its symptom. To this end, the relationship between internal organs and its diseases have been studied from th e viewpoint of the connecting role of the kidney channel of foot-shaoyin. The results of this study are as follows; The function of the kidney has specific re lations with the liver, lung, heart, urinary bladder, throat, tongue, chest, sole of the foot, inside of the thigh and waist. These mutual relations reflect the pathological changes of the kidney. So physiological function and symptom of the kidney can be better understood throu gh the connecting role of the kidney channel of foot-shaoyin on the concept of the organism as a whole. This is the key of the clinical treatment based on the precept sof oriental medicine.

• Journal of Korean Medical classics
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• v.19 no.2 s.33
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• pp.46-52
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• 2006

${\ulcorner}$황제내경(黃帝內經)${\lrcorner}$ 내함한의학이론(內含韓醫學理論) 기중삼응삼양적내용비상난(其中三陰三陽的內容非常難) 기원인사(其原因是)${\ulcorner}$황제내경(黃帝內經)${\lrcorner}$ 중삼음삼양적내용비상복집(中三陰三陽的內容非常複雜), 특별시삼음삼양적시간배속매편화일양(特別是三陰三陽的時間配屬每篇不日樣) 본론문통과관우(本論文通過關于子) ${\ulcorner}$황제내경(黃帝內經)${\lrcorner}$ 중삼음삼양적시간배속진행연구(中三陰三陽的時間配屬進行硏究), 득출여하결론(得出如下結論), 운기지주기순서춰시오행(목화토금수)순서(運氣之主氣順序就是五行(木火土金水)順序), 저설명주기변화주요근거형지변화(這說明主氣變化主要根據形之變化), 운기지객기순서취시기지대(運氣之客氣順序就是氣之大小)(일양(一陽)${\longrightarrow}$이양(二陽)${\longrightarrow}$삼양(三陽)${\longrightarrow}$일음(一陰)${\longrightarrow}$이음(二陰)${\longrightarrow}$삼음(三陰))${\longrightarrow}$, 저설명객기변화주요근거기지변화(這說明客氣變化主要根據氣之變化) ${\ulcorner}$소문맥해(素問脈解)${\lrcorner}$ 적삼음삼양월별배속시음관(11월:태음)(的三陰三陽月別配屬是陰關(11月:太陰)${\longrightarrow}$양관(1월:태양)(陽關(1月:太陽)${\longrightarrow}$음합(3월:궐음)(陰闔(3月:厥廠)${\longrightarrow}$양합(5월:양명)(陽闔(5월:陽明))${\longrightarrow}$음추(7월:소음)(陰樞(7月:少陰)${\longrightarrow}$양추(9월:소양)(陽樞(9月少陽). 태양소음시음양세력적기초(太陽少陰是陰陽勢力的基礎), 소이상위표리(所以相爲表裏). 소양소음시음양세력적중간(少陽少陰是陰陽勢力的中間), 소이사위표리(所以杞爲表裏) 태음궐음시음양세력적전성기(太陰歐陰是陰陽勢力的全盛期), 소이상위표리(所以相爲表裏) 차료리적의사반영경락류주(此表養的意思反映經絡流注). 태음양명경류주신체전면(太陰陽明經流注身體前面), 태양소음경류주신체후면( 太陽少陰經流注身體後面 ), 소양궐음경류주신체측면(少陽厥陰經流注身體側面). ${\ulcorner}$령추경맥(靈樞經脈)${\lrcorner}$적12경맥류주순서시태음양면경(的12經脈流注順序是太陰陽明經)${\longrightarrow}$소음태양경(少陰太陽經)${\longrightarrow}$궐음소양경적표리경락위주(厥陰少陽經的表裏經絡爲主). 수선매기류주태음양명경적이유(首先脈氣流主太陰陽明經的理由), 취시후천수곡정미화호흡대기결합이형성경맥지기(就是後天水穀精微和呼吸大氣結合而形成經服之氣). 지후맥기류주소음태양경(之後脈氣流注少陰太陽經), 설명순행태음양명경적후천영양물질전입한열경락이위신(說明盾行太陰陽陽明經的後天營養物質轉入寒熱經絡而爲寫薪), 기차맥기순해궐음소양경적(其次脈氣盾行厥陰少陽經的), 인위한열경락지화기피궐음소양경지풍기조절이후조절조습경락(因爲寒熱經絡之火氣被厥陰少陽經之風氣調節而後調節操濕經絡), 비여작반시(比如作飯時), 화기취시소음태양경(火氣就是少陰太陽經), 풍기취시궐음소양경(風氣就是厥陰少陽經), 정내지반취시태음양명경.(鼎內之飯就是太陰陽明經). ${\ulcorner}$령추음양계일월(靈樞陰陽緊日月)${\lrcorner}$ 적삼음삼양월별배속주요시추관합합관추순서(的三陰三陽月別配屬主要是樞關闔闔關樞順序). 저양배서적원인시개문화관문과정(這樣排序的原因是開門和關門過程). 재춘하(在春夏), 양경락지맥기여개문관문과정(陽經絡之脈氣如開門關門過程), 수착추관합합관추순서순행(隨看樞關闔闔關樞順序盾行), 재추동(在秋冬), 음경락지맥기여개문폐문과정(陰經絡之脈氣如開門閉門過程), 수착추관합합관추순행(隨看樞關闔闔關樞盾行).

• Korean Journal of Acupuncture
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• v.39 no.3
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• pp.84-90
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• 2022

Objectives : Acupoints are divided into three categories: classical acupoints, extra-acupoints, and Ashi points. The aim of this study was to understand the meaning and features of Ashi points. Methods : We examined the original meaning of Ashi points from the classical medical texts, including the Beijiqianjinyaofang, the Essential Prescriptions Worth a Thousand Gold for Emergencies, and the Huangdi Neijing, the Yellow Emperor's Canon of Internal Medicine. Results : First, the Ashi method is to locate the points for the acupuncture and moxibustion based on the patients' reactions mainly manifested by sensations of comfort and pain, which can help identify not only Ashi points but also classical and extra-acupoints. Thus, Ashi points may or may not match to classical or extra-acupoints, and we propose that Ashi points should not be classified mutually exclusive to classical or extra-acupoints. Second, there are several similarities between Ashi points and myofascial trigger points. They are located by palpation and have no fixed anatomical positions. Patients experience painful but pleasant feeling when Ashi and myofascial trigger points are pressed, and stimulation of these points have treatment effects. Conclusions : We suggest that Ashi method be used to identify the acupoints based on how patients react when these points are pressed. Ashi points may or may not correspond to classical or extra-acupoints, and share traits with myofascial trigger points.

• Journal of Korean Academy of Nursing
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• v.35 no.1
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• pp.135-142
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• 2005

Purpose: This study was aimed at developing an efficient nursing method for the management of constipation by comparing the effects of abdominal meridian massage on the symptoms of constipation. Method: The subjects were determined by the Rome II criteria and the Constipation Assessment Scale from Aug 30 through Sep 26, 2002. They were randomly divided into two groups: one experimental group of 16, another control group of 15. Abdominal meridian massage was given to the experimental group and no massage was given to the control group. The frequency of defecation and severity of constipation by CAS were measured. The data was analyzed with the t-test, $x^2$-test, and repeated measures ANOVA. Results: There was a significant improvement in frequency of defecation, and severity of constipation in the experimental group compared to the control group. Conclusion: Abdominal meridian massage can be considered an effective nursing method for the management of constipation among CVA patients.

• Proceedings of the IEEK Conference
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• 1998.10a
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• pp.825-828
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• 1998

경혈을 대상으로 인체를 진단하는 의료기기들은 경혈점에 미세한 직류전류를 인가하고, 이 점에서의 전기저항과 세포의 분극에 의해 반응하는 경락체계의 균형상태를 측정하여 인체를 종합적으로 진단한다. 따라서 전 과정이 정확한 경혈의 위치에서 이루어져야만 치료효과와 진단의 신뢰성이 보장된다. 그러나 대부분의 경락관련 치료기들이 정확한 혈위식별에 어려움이 있고 사용자의 전문적 숙련을 요구한다. 따라서 선행연구에서 일정한 주파수로 교호되는 자극패턴(SPAC) 방식을 사용하여 식별률을 높인 혈위식별기 DM96A-1를 개발하였다. DM96A-1은 단일전원이 양방향으로 교호되는 전류로 자극펄스를 출력하고 측정범위가 0.5∼50㎂인 전류메터와 레벨메터를 이용하여 혈위의 전류량을 표시한다. 이에 따라 방향전환 소자의 두 채널 제어신호가 교호되는 과도기에서 두 자극패턴의 중첩 도통에 의해서 누설전류가 발생하는 경우가 있으며 이를 제거하기 위하여 정밀한 조정을 필요로 하는 불편이 있었다. 따라서 이와 같은 단점들을 보완하여 신뢰성 있는 출력 파라메터를 얻을 수 있도록 마이크로프로세서 i80c196kc를 사용하여 DM96A-2를 재 설계하였으며 임상실험에 의하여 개선된 최적 파라메터의 타당성을 검증하였다.

• Korean Journal of Acupuncture
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• v.39 no.2
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• pp.68-69
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• 2022

• Korean Journal of Acupuncture
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• v.40 no.4
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• pp.194-205
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• 2023

Objectives : This study investigated the current utilization status of thermotherapy devices in Korean medicine (KM) institutions and identified areas for improvement and further development, as perceived by KM doctors (KMDs). Methods : An online survey was conducted, targeting KMDs primarily engaged in clinical patient care. The questionnaire included items about respondents' clinical practices, the extent of thermotherapy device usage, their opinions on these devices, and perceived improvement needs. The collected data underwent quantitative analysis. Results : From the 1,025 respondents, data from 862 respondents who provided complete responses were analyzed. On average, respondents utilized thermotherapy treatments for 80% of their patients. Infrared (IR) phototherapy unit, electrical moxibustion apparatus, and heater-based thermotherapy devices were predominantly owned by respondents, with IR being the most frequently used. The average satisfaction score for current thermotherapy devices was 79. A significant concern raised was the necessity for improved health insurance coverage and efficacy evaluation. Conclusions : This research has confirmed that the extensive use of thermotherapy devices by KMDs in treating primarily musculoskeletal and gastrointestinal ailments - common conditions among patients in KM institutions. The main areas identified for improvement encompass safety, cost-effectiveness, and device efficacy. Future enhancements in thermotherapy devices should address these crucial aspects.

• The Journal of the Korea Contents Association
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• v.9 no.12
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• pp.710-717
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• 2009

The researchers and planners are using patent/paper map system to analyze the research trend, but we can't use the existing analysis system because of the specialty of korean traditional medicine. Thus we deduced the analysis models from preceding research and system and designed 14 analysis models which are composed of basic, detail and complex models. We verified the analysis models using papers which has 'meridian' keyword among 16,000 papers stored in OASIS. From the analysis result, we know that the meridian study has just entered in the maturity and is closely related with other parts of korean traditional medicine as physiology etc. And we verified the proposed analysis model from the comparison with the analysis models of preceding systems. The analysis model will be used for the development of Korean traditional medicine paper map analysis service scenario and system.