• Title/Summary/Keyword: 경과실

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Clinical Features of Cholestatic Hepatitis (담즙정체성 간염의 임상적 양상)

  • Choi, Sun-Taek;Eun, Jong-Ryul;Lim, Song-Woo;Kim, Bong-Jun;Lee, Heoon-Ju;Gu, Mi-Jin;Choi, Joon-Hyuk
    • Journal of Yeungnam Medical Science
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    • v.18 no.1
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    • pp.51-58
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    • 2001
  • Background: Cholestatic hepatitis is failure of bile to reach the duodenum with hepatocellular damage and no demonstable obstruction of the major bile ducts. The prognosis is usually good with recovery in less than 4 weeks after withdrawal of the offending drug. However, a prolonged course lasting over 3 months is possible and, in rare cases, progression to ductopenia with development of a vanishing bile duct syndrome occurs. A differential diagnosis with other causes of Chronic liver disease is needed. Materials and Methods: From January 1991 through January 2000, 14 patients diagnosed as cholestatic hepatitis by liver biopsy were included. The possible causative drug, clinical features, laboratory findings, and progression of cholestatic hepatitis were evaluated. The semiquantitative study of liver lesions was performed by two independent observers. Results: Causes of cholestatic hepatitis are 5 cases of oriental medicine, 3 cases of anti-tuberculosis medication, 1 case of ticlopidine and antibiotics and 4 cases of unknown causes. The clinical features of cholestatic hepatitis were jaundice, itching, urine color change, and general weakness. During 6 to 30 months, LFT of 5 patients showed prolonged elevation. Elevated total cholesterol ${\geq}$250 mg/dL in 6 patients, pheripheral blood eosinophilia in 5 patients, auto-antibody positive in 6 patients were observed respectively. The biopsies showed intralobular bilirubinostasis with a mixed portal inflammatory infiltration. Conclusion: In cholestatic hepatitis, durations of abnormal LFT are variable regardless of causative drugs. If cholestatic hepatitis progresses toward chronic course, viral hepatitis, primary biliary cirrhosis, and autoimmune hepatitis should be differentially diagnosed and sequential liver biopsies are needed.

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Improvement of Katsuobushi smoking machine for the reduction of benzo(a)pyrene (가쓰오부시 훈연기 개선 및 벤조피렌 저감화)

  • Hong, Ju Hee;Hwang, Sang Min;Lee, Seung Ju
    • Korean Journal of Food Science and Technology
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    • v.49 no.2
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    • pp.162-167
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    • 2017
  • A Katsuobushi smoking machine was developed and evaluated to determine its benzo(a)pyrene reducing effect. The machine was equipped with two heaters for smoking and chamber heating. The smoke-generating system was equipped with a cadmium sulfide (CdS) smoke sensor, an on/off controller, and a rotating feeder with a smoke inlet. Raw bonito was steamed and then smoked under three smoke levels. After smoking at $45^{\circ}C$ for 108 h, the benzo(a)pyrene concentrations were 5.87, 7.83, and $11.41{\mu}g/kg$ at the low, middle, and high smoke levels, respectively. The benzo(a)pyrene concentrations after low-level smoking at 45, 65, and $85^{\circ}C$ for 108 h were 5.87, 4.82, and $3.27{\mu}g/kg$, respectively. Accordingly, the optimal conditions for benzo(a)pyrene reduction were a lower smoke level and higher smoking temperature. These optimal smoking conditions can be implemented with the newly developed machine, but is not possible using a conventional Katsuobushi smoking machine.

Large-scale Levee Monitoring Experiment Using Fiber-optic Sensor and Distributed Temperature Sensing System (광섬유 센서와 분포형 온도 센싱 시스템을 이용한 실규모 제방 모니터링 실험)

  • Ahn, Myeonghui;Bae, Inhyeok;Ji, Un;Kang, Joongu
    • Ecology and Resilient Infrastructure
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    • v.7 no.3
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    • pp.181-188
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    • 2020
  • In this study, a temperature distribution sensing method using optical fiber was applied to a large-scale levee experiment, and the applicability of wide-area levee or embankment monitoring technology to observe the changes inside the levee was reviewed. The optical fiber was buried in a large-scale levee, and the temporal and spatial temperature changes were measured according to the water level changes in the reservoir. As the water level of the reservoir increased, the temperature of the embankment slope decreased, and as the infiltration progressed, a change in the spatial location of the temperature change was detected. The temperature change due to embankment infiltration varied depending on the time of the infiltration progress, and the change assumed to be the seepage line could be observed. This study has demonstrated that information about temperature changes inside the levee can be interpreted as the information on the locations that are judged to be relatively vulnerable, investigating the changes in the condition inside the levee.

Arthritis in the Subacute Stage of Kawasaki Disease after Responding to Intravenous Immunoglobulin Treatment (가와사끼병에서 정맥용 면역글로불린에 반응 후 아급성기에 발생한 관절염)

  • Lee, Kyung-Yil;Oh, Jin-Hee;Koh, Dea-Kyun
    • Clinical and Experimental Pediatrics
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    • v.46 no.11
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    • pp.1124-1127
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    • 2003
  • We evaluated the clinical and laboratory characteristics of five children with Kawasaki disease who had showed arthritis after responding to intravenous immunoglobulin(IVIG) treatment. Age distribution was between 13 months and six years of age(mean $3.2{\pm}1.6$ years). There were two males and three females. Arthritis occurred when acute symptoms were subsiding, with the average onset on day $5.8{\pm}1.8$ after final IVIG treatment. Arthritis was pauciarticular in three, and polyarticular in two. Regarding laboratory findings, one child was positive in rhematoid factor and changed to negative after two months. Three patients were examined for HLA B27 and all showed negative results. High dose aspirin(two cases), anti-inflammatory drug(ibprofen, three cases), and corticosteroids(methyprednisolon pulse therapy, one case) were used for this type of arthritis. Symptoms and signs of arthritis in all patients were improved by these therapies. There was no relapse or complications within six months. Arthritis after responding to IVIG therapy was rarely observed in children with Kawasaki disease. This type of arthritis responded well to anti-inflammatory drugs including corticosteroids, and showed no relapses.

Sensory and Instrumental Texture Properties of Songpypyuns and Mosipulpyuns According to the Cooking Conditions (여러가지 조리방법에 따른 송피떡과 모시풀떡의 관능적, 기계적 텍스쳐 특성)

  • 김순임;한영실
    • Korean journal of food and cookery science
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    • v.9 no.3
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    • pp.187-194
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    • 1993
  • Effects of the steaming conditions on textural and sensory quality of rice cakes were investigated with respect to storage period. All steaming methods except microwave oven cooking were not remarkably decreased in moisture content during storage. Degree of gelatinization was shown much higher in the both of rice cakes prepared by the rice-cake steamer and steaming pot than those of microwave oven cooking sample. Effect of the different steaming conditions on the rice cake quality resulted that the sensory profiles (consistency, moistness and cohesiveness) were apparently improved in the cakes prepared with rice-cake steamer and steaming pot cooking than microwave oven cooking. The highest overall quality was shown in the samples cooked by rice-cake steamer. The rice cakes prepared by microwave oven showed the highest hardness and chewiness in the textural profiles, whereas the rice cakes prepared by the rice-cake steamer and the steaming pot showed the high gumminess.

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Prosthetic treatment for patient with anterior overbite and partial edentulism using maxillary hybrid telescopic double crown RPD and mandibular fixed prostheses: A 11-yr follow-up (전치부 과개교합을 가진 상하악 부분 무치악 환자에서의 상악 하이브리드 텔레스코픽 이중관 국소의치와 하악 고정성 보철물을 이용한 치료의 11년 경과관찰 증례)

  • Choi, Hyunsuk;Cho, Jin-Hyun
    • The Journal of Korean Academy of Prosthodontics
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    • v.59 no.4
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    • pp.415-421
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    • 2021
  • The biomechanical prognosis of conventional removable partial denture is questionable in case of patient with few remaining teeth or periodontally compromised teeth. In this case, hybrid telescopic double crown RPD may be a successful treatment alternative. Hybrid telescopic double crown RPD has following advantages over conventional RPD: secondary splinting effect between abutments, more vertical stress direction and more convenient in repairing the denture after extraction of abutment tooth. In this clinical case, patient had deep overbite in anteriors and partially edentulous. The maxilla was restored with hybrid telescopic double crown RPD and the mandible was restored with implants and fixed prostheses. Long-term follow-up and supportive periodontal treatment were performed, and satisfactory results were achieved in terms of function and aesthetics.

In vitro Multiple-propagation of Wolly Grass (Imperata cylindrica 'Rubra') (홍띠(Imperata cylindrica 'Rubra') 기관분화에 의한 기내대량증식)

  • Kang, In-jin;Kantayos, Vipada;Choi, Jong Young;Lee, Ye-Jin;Bae, Chang-Hyu
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.04a
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    • pp.79-79
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    • 2019
  • 홍띠(Imperata cylindrica 'Rubra') 식물자원의 기내대량증식과 재분화식물체의 순화체계를 구축하고자 기내 재분화에 적합한 식물재료부위, 생장조절물질을 조사하고, 재분화 유식물체로부터 적정 순화조건을 구명하였다. 기본배지로 MS (Murashige and Skoog, 1962) 배지를 사용하였고, 배양은 $26{\times}2^{\circ}C$, $25{\mu}mol/m^2/s$, 14h/10h (day/night) 광조건 하의 배양실에서 수행하였다. 캘러스 형성은 뿌리 끝, 줄기절편, 생장점 부위 중생장점 부위에서 가장 양호하였고, 이 생장점 조직에 0.1 mg/L의 2,4-D와 2 mg/L의 BA를 처리하였을 때 양호하였다. 캘러스 증식은 0.1 mg/L의 2,4-D와 0.05 mg/L의 BA 배지, 0.05 mg/L의 2,4-D와 0.5 mg/L의 BA를 첨가한 배지 중 0.1 mg/L의 2,4-D와 0.05 mg/L의 BA 배지에서 양호하였고, 이들 캘러스로부터 신초 재분화는 0.01 mg/L의 NAA와 2 mg/L의 BA 처리에서 양호하였다. 초기 치상으로부터 실제 경과시간은 캘러스 유도에 19주간(2018. 03. 18~07. 27), 캘러스 증식 9주간(2018. 07. 27~09. 28), 신초 유도 11주간(2018. 09.28~12. 14), 순화에 10주간(2018. 12. 14~2019. 02. 23)에 걸쳐 진행하였으나 확립된 배양계를 적용하면 캘러스 유도 4주, 캘러스 증식 3주, 신초유도 및 증식 4주, 순화 7주 정도가 소요될 것으로 계측되었다. 순화는 다경줄기 형성후 MS배지를 멸균한 상토(버미큘라이트) 또는 종이포트로 교체하여 재분화식물체를 배양병에서 7주간 배양하고, 7주후에 배양병 뚜껑을 1/10 정도 1차 개방하여 1주일 후 3/10 정도 개방하여 2주간 경과한 후 컵포트(직경 6 cm)에 이식하여 성공적으로 활착시켰다.

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크릴과 아스타크쟌틴 첨가량에 따른 붉은쏨뱅이 (Sabastiscus tertius)의 체색변화와 성장

  • 김철원;백재민;황은경;임상구;김광수
    • Proceedings of the Korean Aquaculture Society Conference
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    • 2003.10a
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    • pp.82-83
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    • 2003
  • 최근 인공종묘생산기술이 개발된 붉은쏨뱅이(Sabastiscus tertius)는 자연산과 양식산의 체색이 붉은색과 검정색으로 많은 차이가 있어 양식산업화에 많은 어려움이 있다. 따라서 상품가치와 경쟁력 향상을 위하여 사료에 카로티노이드 성분을 함유한 크릴새우(25, 50, 75, 100%)와 astaxanthin(5, 10, 15, 20%)를 비율대로 첨가하여 양식산 붉은쏨뱅이의 체색 변화를 살펴보았다. 크릴새우의 경우 50% 첨가한 사료실험구에서의 적색도와 황색도는 각각 6.29와 13.42로 높게 나타나기 시작하였으며 크릴새우 75% 첨가실험구에서는 적색도와 황색도가 각각 8.31과 14.91로 최고치를 보였다. 그리고 크릴 100%에서는 적색도와 황색도가 각각 7.27과 10.33로 75% 실험구에 비하여 감소하는 것으로 나타났다. astaxanthin 실험구들에서는 5%와 10% 실험구에는 체색도가 높게 나타나지 않았으나 15%에서 적색도가 7.86 황색도가 9.32로 가장 높게 나타났다. 그리고 20% 실험구에는 7.18과 6.32로 나타났다. 본 실험결과 붉은쏨뱅이의 체색회복을 위해서는 크릴새우의 경우 최소 50% 이상을 첨가해야만 가능할것으로 판단되며 astaxanthin는 15% 이상 첨가해야 효과가 있는 것으로 판단된다. 그리고 astaxanthin보다는 크릴새우가 더 효과적이였으며 모든 실험구는 대조구(펠렛사료 100%)에 비하여 체색 회복효과가 있는 것으로 나타났다. 또한 자연산에서는 적색도와 황색도는 각각 23.80과 13.44로 적색도가 아주 높게 나타났으나 양식산에서는 적색도와 황색도가 1.09와 1.98로 매우 낮게 나타났다. 그리고 체색의 변화는 모든실험구에서 등지느러미와 꼬리지느리미 그리고 턱과 가슴주변에서부터 점차 배와 등쪽으로 색이 변화하는 것이 관찰되었다. 크릴 75%와 astaxanthin 15%를 공급하였을 때 체색이 변화하는 시간은 크릴의 경우 사료공급 20일 후부터 체색의 변화가 시작하여 30일이 경과 될때에는 등지느러미, 꼬리지느러미 및 턱주변이 붉은색으로 변화하였다. astaxanthin의 경우는 30일부터 등지느러미와 꼬리지느러미 부근에서 체색의 변화가 시작되었으며 40일 이후부터 붉은색으로 변화하였다. 크릴새우와 astaxanthin를 함유하여 실험하였을 때 붉은쏨뱅이의 성장은 크릴 75% 실험구에서 전장 172.3mm, 체중 65.9g으로 가장 좋았다. 그러나 대조구에서는 전장 148.7mm, 체중 49.5g으로 가장 성장이 저조하였으며 astaxanthin 실험구들에서는 전장 152.3~159.8mm, 체중 56.9~59.3g으로 서로 유의적인 차이를 나타내지 않았다.

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Study on the Temperature Distribution of Cabin under Various Car Heating Modes (난방기 출력에 따른 철도차량 객실 내부 온도 분포 분석)

  • Cho, Youngmin;Yoon, Young-Kwan;Park, Duck-Shin;Kim, Tae-Wook;Kwon, Soon-Bark;Jung, Woo-Sung;Kim, Hee-Man
    • Journal of the Korean Society for Railway
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    • v.15 no.6
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    • pp.558-565
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    • 2012
  • Abnormal climate or weather is more frequently reported nowadays due to the global climate change. Especially, extremely low temperature in winter season may cause bad thermal discomfort of passengers. In this study, the effect of car heating modes on cabin temperature change and distribution was studied by using a real-scale environmental chamber for passenger cabin. It was found that the cabin temperature rose quickly at the initial stage of heating system operation, but it stopped increasing after certain point. And, temperature was higher when the height from the floor was higher. Based on the obtained result, the way to minimize the decrease of passengers' thermal comfort was suggested.

EFFECT OF THE SHIP NOISE ON THE INTELLIGENCE ABILITY OF MAN (선박소음이 인간지능력에 미치는 영향에 관한 연구)

  • PARK Jung-Hee
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.8 no.3
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    • pp.127-132
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    • 1975
  • This is an experimental study that aimed to find out a possible relationships between the noise of the ship and the intelligent quotient, and the creativity of the crew member during June 5, to August 24, 1975. The experiment was carried out on the university training ship, the Oh-Bae-San Ho(1,126 tons), and the Kwan-Ak-San Ho (243 tons) and the training ship Baek-Kyung Ho (380 tons) of Je-ju College, where the total number of 144 students engaged on their tasks of practical exercise. And the following results were obtained : The decreases of I.Q. was evident as compared to the score obtained at the class room; soon after the embarking of the ship, the students on the deck decreased the score by $7\%$ of what they obtained at the class room while the students in the engine room decreased by $13\%$. The I.Q. was regaining the normal state after three days of embarking seemingly showing the fact that the students became adapted to the noise of the ship, but no remarkable improvement was visible during the period of 3 days to 35 days on the ship. One of the remarkable fact that had not been expected was that the problems for audio discernment was much easily solved in the midst of noise that made oral communication impossible (102 dB) than in the place of noise where conversation was possible(67 dB).

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