• Title/Summary/Keyword: 건의

Search Result 8,902, Processing Time 0.039 seconds

Systematic Review of the Effect of Glucosamine on Joint Health while Focused on the Evaluation of Claims for Health Functional Food (건강기능식품의 기능성을 중심으로 한 글루코사민의 관절건강 기능성에 대한 체계적 고찰)

  • Kim, Joohee;Kim, Ji Yeon;Kwak, Jin Sook;Paek, Ju Eun;Jeong, Sewon;Kwon, Oran
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.43 no.2
    • /
    • pp.293-299
    • /
    • 2014
  • Although the functional ingredient has been evaluated based on scientific evidence by the Ministry of Food and Drug Safety (MFDS), the levels of scientific evidence and consistency of the results might vary according to the emerging data. Therefore, a periodic re-evaluation may be needed in some functional ingredients. In this study, we re-evaluated the scientific evidence for the joint health of glucosamine as a functional ingredient in health functional food. Literature searches were conducted using Pubmed, Cochrane, KISS, and IBIDS databases with the search term of glucosamine in combination with osteoarthritis. The search was limited to human studies published in English, Korean and Japanese. Using the MFDS's evidence based evaluation system for scientific evaluation of health claims, 34 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting the relation between glucosamine and joint health. Among the 34 studies, significant effects for joint health were reported in 28 studies, and their daily intake amount was 1.5 to 2 g. Eleven out of 34 studies were identified, excluding severe radiographic osteoarthritis, and ten from those eleven studies reported significant effects for joint health. Based on this systematic review, we concluded that there was possible evidence to support a relation between glucosamine intake and joint health.

A Survey of Zearalenone in Beans Using High Performance Liquid Chromatography-Fluorescence Detector (HPLC-FLD) and Ultra Performance Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) (HPLC-FLD 및 LC-MS/MS에 의한 두류 중 제랄레논 오염실태 조사)

  • Jang, Mi-Ran;Lee, Chang-Hui;Lee, Hyo-Jeong;Kim, Ji-Yeon;Son, Sang-Hyeok;Sin, Chun-Sik;Kim, So-Hui;Kim, Dae-Byeong
    • Korean Journal of Food Science and Technology
    • /
    • v.40 no.3
    • /
    • pp.354-359
    • /
    • 2008
  • A survey for zearalenone contamination was conducted on 27 soy bean samples, 27 red bean samples, 16 black bean samples, 19 seoritae samples, 14 seomoktae samples, for a total of 127 commercial Korean samples. Zearalenone was quantified by the immunoaffinity column clean-up method with high performance liquid chromatography-fluorescence detection (HPLC-FLD), and was confirmed by liquid chromatography tandem mass spectrometry(LC-MS/MS). The limits of detection and quantification were $2.0{\mu}g/kg$ and $6.0{\mu}g/kg$, respectively. The recovery in the beans ranged from 82.2 to 98.4%. According to HPLC-FLD, zearalenone was detected in 13 samples (10.2% incidence), including 1 soybean and 12 red bean samples. The zearalenone contamination levels were in the range of 8.01${\sim}38.98{\mu}g/kg$. Finally, LC-MS/MS analysis was conducted in the contaminated samples to verify the results of HPLC-FLD. The LC-MS/MS results confirmed the presence of zearalenone in all 13 samples. The contamination level was lower than that of EU, which is below $100{\mu}g/kg$ for raw grains.

Distribution of Sexually Transmitted Viral Diseases in Busan (부산지역 바이러스성 성병 감염양상 연구)

  • Cho, Kyung-Soon;Na, Young-Ran;Joe, Hyeon-Cheol;Lee, Jung-Hee;Jung, Myung-Ju
    • Korean Journal of Microbiology
    • /
    • v.42 no.3
    • /
    • pp.177-184
    • /
    • 2006
  • This study was performed to evaluate the prevalence of high risk Human papilloma virus (HPV), Herpes simplex virus type 1, 2 (HSV-1,2), Hepatitis B virus (HBV) and Human Immuno deficiency virus (HIV) infection with sexual transmitted viral diseases in Busan during 2004 to 2005. six hundred seventy four samples of cervical swabs were tested for sexually transmitted viral diseases. Among the isolated viruses, 23 (3.4%) samples were HPV and 3 (0.4%) and 9 (1.3%) samples were HSV 1 and 2, respectively. Among the 586 serum samples tested for viruses, HSV IgM 121 (3.6%), HSV-1 IgG 487 (83.1%), HSV-2 IgG 135 (23.0%), HBsAg 26 (4.4%), HBeAg 7 (1.2%), and HIV (0%) types were found. HPV genotypes were detected in 16 patients, of which 13 cases were high risk type HPV, 3 cases were low risk type HPV, and multi infection were detected in 7 cases. In the age distribution of the patients, 7.2% of infection tested from cervical swabs occurred in under the age of 20, while 100% of infection was found to occur in those who were 40 years old or older in the serum samples. The outbreak pattern in their occupations was found to be the highest at the health organization (amusement quarter) for the cervical swabs, and at infirmary (commercial sex worker) for the serum samples, respectively.

Prevalence and Toxin Genes of Food-Borne Pathogens Isolated from Toothbrush in Child Care Center (보육시설 유아 사용 칫솔의 식중독 미생물 분포 및 독소 유전자)

  • Kim, Jong-Seung;Kim, Jung-Beom
    • Journal of Food Hygiene and Safety
    • /
    • v.30 no.3
    • /
    • pp.242-248
    • /
    • 2015
  • This study was performed to investigate the microbiological contamination on toothbrushes, toothbrush caps, and tooth cleaning cups in the child care centers and to evaluate the toxin genes, toxin production ability and antibiotic resistance of food-borne pathogens. The average number of total aerobic bacteria and fungi were 5.3 log CFU and 3.2 log CFU. Coliform bacteria were detected in 41 (54.7%) of 75 toothbrushes, 13 (44.8%) of 29 toothbrush caps, and 29 (44.6%) of 65 tooth cleaning cups. Salmonella spp. was not detected in all of samples but Bacillus cereus was isolated from 1 (1.3%) of 75 toothbrushes and 2 (3.1%) of 65 tooth cleaning cups. Staphylococcus aureus was detected in 1 (1.5%) of 65 tooth cleaning cups. The nheA, nheB, nheC, hblC, hblD, hblA and entFM toxin genes were possessed in B. cereus isolated from toothbrush which also produce NHE and HBL enterotoxins. S. aureus was resistant to ampicillin and penicillin, while B. cereus was resistant to ${\beta}-lactam$ antibiotics. These results indicated that the sanitary conditions of toothbrushes and tooth cleaning cups in the child care centers should be improved promptly. The UV sterilization after drying and then storage in dried condition is required to improve the sanitary condition of toothbrushes and tooth cleaning cups in the child care center.

Monitoring of Sulfur Dioxide Residues in Commercial Herbal Medicines at Domestic by Geographical Origins (원산지별 국내 유통 한약재의 이산화황 잔류실태 조사)

  • Lee, Ah Reum;Jang, Seol;Lee, A Yeong;Choi, Goya;Kim, Ho Kyoung
    • Journal of Food Hygiene and Safety
    • /
    • v.29 no.2
    • /
    • pp.152-157
    • /
    • 2014
  • This study was carried out to investigate the residual sulfur dioxide residues ($SO_2$) in commercial medicinal herbs in Korea in 2013. Among a total of 116 samples of 11 different kinds of herbs, 71 samples (11 Kinds) were domestic, and 45 samples (10 Kinds) were imported. The residual contents of $SO_2$ in the samples were determinated by a modified Monier-Williams method. Of the 116 samples, 6 samples (5.2%, 4 Kinds) failed to meet the regulations for sulfur dioxide residues of KFDA in medicinal herbs. Among 6 unsuitable samples, 1 samples (1.4%) were domestic, and 5 samples (11.1%, 3 Kinds) were imported. The highest amount of sulfur dioxide residues was 1546.3 mg/kg (Lycii Fructus) in the domestic samples. Regardless of region, $SO_2$ contents were not found at Anemarrhenae Rhizoma, Citri Unshius Pericarpium, Eucommiae Cortex, Forsythiae Fructus, Gardeniae Fructus, Leonuri Herba and Lonicerae Folium et caulis. These data will be used as a basic data for the future legislation on the regulation and control of sulfur dioxide of herbal medicines.

Survey of Mycotoxin Contamination in Grains and Grain Products (곡류 및 곡류가공품 중 곰팡이독소 오염도 조사 연구)

  • Yang, Yongshik;Lee, Hyang Hee;Kim, Ae Gyeong;Ryu, Keun Young;Choi, Su Yeon;Seo, Doo Ri;Seo, Kye Won;Cho, Bae Sik
    • Journal of Food Hygiene and Safety
    • /
    • v.34 no.2
    • /
    • pp.205-211
    • /
    • 2019
  • This study surveyed mycotoxin contamination in grains and grain products, which were purchased from supermarkets and traditional markets from October 2017 to September 2018 in Gwangju (Metropolitan City). A total of 127 samples including adlay, sorghum, millet, rice, oats, barley, buckwheat, corn as grains, and rice flour, buckwheat flour, roasted barley and corn, as grain products were surveyed. The tested mycotoxins were aflatoxin ($AFB_1$, $AFB_2$, $AFG_1$, $AFG_2$), fumonisin ($FUB_1$, $FUB_2$), ochratoxin A (OTA), and zearalenone (ZON). Mycotoxins were analyzed simultaneously with a UPLC-tandem mass spectrometry method. Fumonisin ($B_1+B_2$) was detected at the range of $4.8{\sim}738.5{\mu}g/kg$ in 35 samples and zearalenone at $8.4{\sim}507.6{\mu}g/kg$ in 20 samples, respectively. No other mycotoxins were detected. Risk assessment was evaluated by using estimated daily intake (EDI) and provisional maximum tolerable daily intake (PMTDI) in accordance with the Joint FAO/WHO Expert Committee on Food Additives (JECFA). When the hazard index (HI) was expressed as $(EDI/PMTDI){\times}100$, the HI (%) showed in the range of 0.0019~1.9526%. Based on these results, mycotoxin concentrations in the grains and grain products were within safe levels.

Evaluation of Residual Pesticides in Dried Chili Peppers and Chili Powders Using LC-MS/MS (LC-MS/MS를 이용한 유통 건고추와 고춧가루의 잔류농약 평가)

  • Jang, Mi-Ra;Kim, Eun-Hee;Shin, Jae-Min;Park, Young-Hye;Park, Hae-Won;Kim, Jin-Kyoung;Hong, Mi-Sun;Yu, In-Sil;Shin, Young-Seung
    • Journal of Food Hygiene and Safety
    • /
    • v.36 no.1
    • /
    • pp.9-16
    • /
    • 2021
  • The monitoring of residual pesticides in dried chili peppers and chili powders, which are circulated in Seoul from 2018 to 2019, was conducted for safety evaluation. As a result of analyzing for 71 kinds of pesticide residues in 101 cases of samples, pesticides were detected in 87 samples; however, no samples exceeded the MRLs (Maximum Residue Limits). Detection rates of pesticides in dried chili peppers and chili powders were 73.3% and 91.5%, respectively. The detection rate of residual pesticides in chili powders was a little higher than that in dried chili peppers. Twelve types of pesticides were detected, however, those pesticides were acceptable to use on peppers, according to the Crop Protection Guidelines. The most frequently detected pesticide was pyraclostrobin followed by flubendiamide, azoxystrobin, and chlorantraniliprole. The risk for detected pesticides was estimated as the ratio of ADI (Acceptable Daily Intake) to food intake rate. The ADI value resulting by intake of dried chili peppers and chili powders was in the range of 5.66E-05 to 3.34E-02, which was within a safe level.

Contents of Mercury, Methylmercury, and Selenium in Deep-Sea Fishes (심해성 어류의 수은, 메틸수은 및 셀레늄 함량)

  • Yun-Sik Cho;Seon-Il Hwang;Sang-Woon Shin;Hyun-Ju Kim;Ji-Yeon Lee;Ji-Won Song;Jeong-Eun Kim;Byoung-Hoon Lee;A-Ra Mo;Myeong-Ki Park
    • Journal of Food Hygiene and Safety
    • /
    • v.38 no.3
    • /
    • pp.158-163
    • /
    • 2023
  • This study aimed to determine mercury (Hg), methylmercury (MeHg), and selenium (Se) levels in deep-sea fishes distributed in Gyeonggi-do, South Korea. Concentrations of Hg, MeHg, and Se were measured by using a mercury analyzer and Inductively Coupled Plasma - Mass Spectrometry (ICP-MS). The average content (mg/kg) in the seafood samples was as follows: Hg, 0.7647 (0.0182-5.3620), MeHg, 0.0764 (0.0096-0.8750), and Se, 0.4728 (0.1075-3.5100). All the levels of MeHg were below the recommended standards of the Ministry of Food and Drug Safety i.e., <1.0 mg/kg. Recent studies have shown that Se prevents Hg toxicity. The average daily intake in humans was 3.3 ㎍/kg, which was lower than the recommended amount (50-200 ㎍/person/day). The weekly intake of Hg and MeHg was calculated to be 6.07% and 1.90%, respectively, of the provisional tolerable weekly intake (PTWI). This study showed that the weekly intake of Hg and MeHg from abyssal fish was less than the PTWI recommended by the Joint FAO/WHO expert committee on food additives. Therefore, the levels reported in this study are presumed to be adequately safe.

A Research on the Improvement of Human Factors for the Prevention of the Helicopter Accidents (회전익 항공기 사고예방을 위한 인적요인 향상에 관한 연구)

  • Choe, Jin-Guk;Yu, Tae-Jeong
    • 한국항공운항학회:학술대회논문집
    • /
    • 2016.05a
    • /
    • pp.79-83
    • /
    • 2016
  • 1990년부터 14년간 총 65건의 회전익 사고가 발생하여 연 평균 4.6건의 사고가 발생하였다. 항공대국으로 안전한 수준에 이르기 위하여 회전익 항공기 사고의 잠재적 조건 선행 분석자료 및 연구결과 등을 활용하여 회전익 항공기 항공안전대책을 살펴보았다. 소방항공의 경우 인적요인이 사고 발생원인의 57%로 주 요인으로 나타났으며, 국가기관에서도 2000년 이후 사고 중에서 인적요인이 주 요인으로 인적요인이 중요한 개선대상으로 밝혀졌다. 항공안전 전문가들과 인터뷰를 실시하여 회전익 항공기의 잠재 조건에 대해 논의하였다.

  • PDF

The Distribution of Injuries by Hours of the Day in Construction (건설공사 재해의 시간대별 발생빈도)

  • 이규진
    • Proceedings of the Korean Institute of Industrial Safety Conference
    • /
    • 2002.11a
    • /
    • pp.347-350
    • /
    • 2002
  • 수년간 건설업은 제조업을 비롯한 다른 산업에 비해 높은 재해율을 보이고 있다. 건설투자의 증가는 2001년과 2002년 각각 7.4%와 12%씩 증가하였으나, 재해발생건수는 2001년(16771건)은 2000년(13500건)에 비해 24% 증가하였고 2002년 상반기(8853건)는 2001년 상반기(6636건)보다 33%나 증가하여 건설투자의 증가율보다 높았다. 더욱이 건설취업자수가 2001년(1581천명)의 경우 전년(1575천명)에 비해 0.4%가 감소되었음을 감안할 때 건설물량의 양적 증가에도 불구하고 안전관리에는 소홀한 면이 많았으며 재해예방을 위한 적극적인 노력이 요구된다.(중략)

  • PDF