• Journal of Life Science
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• v.33 no.6
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• pp.455-462
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• 2023

During pregnancy, maternal immune activation (MIA) from infection increases the risk of neurodevelopmental diseases, including schizophrenia and autism spectrum disorders. MIA induced by polyinosinic-polycytidylic acid (poly (I:C)) and lipopolysaccharide (LPS) in animal experiments has led to offspring with abnormal behaviors and brain development. In addition, it has recently been reported that microglia, which reside in the brain and function as immune cells, play an important role in behavioral abnormalities and brain development in MIA-induced offspring. However, the underlying mechanism remains unclear. In this study, we investigated whether microglia-specific inhibition of GPR56, a member of the G protein-coupled receptor (GPCR) family, causes behavioral abnormalities in brain development. First, MIA induction did not affect the microglia population, but when examining the expression of microglial GRP56 in MIA-induced fetuses, GPR56 expression was inhibited between embryonic days 14.5 (E14.5) and E18.5 regardless of sex. Furthermore, microglial GPR56-suppressed mice showed abnormal behaviors in the MIA-induced offspring, including sociability deficits, repetitive behavioral patterns, and increased anxiety levels. Although abnormal cortical development such as that in the MIA-induced offspring were not observed in the microglial GPR56-suppressed mice, their brain activity was observed through c-fos staining. These results suggest that microglia-specific GPR56 deficiency may cause abnormal behaviors and could be used as a biomarker for the diagnosis and/or as a therapeutic target of behavioral deficits in MIA offspring.

• Smart Media Journal
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• v.6 no.1
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• pp.30-38
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• 2017

Medically Unexplained Symptoms (MUS) are cases of symptoms of the disease which are no reasons of cause of illness. The patients of MUS have been treated with cognitive behavioral therapy. Food Art Therapy (FAT) is subtype of Art Therapy which is kind of cognitive behavioral therapy. The patients of MUS　will be satisfied by preparing and untaking foods. Through development of smart phone, the supply of smart phone in older populations have dramatically increased. But, the use of a smart phone or a very low. The importance of smart phone application development will been introduced wild vegetables of Korean traditional medical book for elderly patients in MUS. The patients will be increased confidence by making foods and intakeing food will be effective to prevent the disease.

• Journal of Industrial Convergence
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• v.21 no.9
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• pp.23-32
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• 2023

Interest in Serious Games for Healthcare (SGHs) that can improve health through games is increasing. Digital Therapeutics (DTx) is a treatment that must be approved for effectiveness and safety, so it should follow the traditional drug distribution method, but SGHs are wellness products that are more flexible in terms of adoption and diffusion than DTx. SGHs are effective because it can provide customized services through continuous monitoring and feedback. When SGHs are applied to cognitive impairment treatment or behavioral correction, malfunctions and side effects are minor. This study developed research model based on the Valence Framework, gathered data from 142 undergraduates, and demonstrated that only the perceived benefits have a statistically significant positive (+) effect on SGHs acceptance intentions. Based on these results, this study suggests that SGHs companies should promote benefits in accepting SGHs for general users and they need for a distribution and analytics platform strategy based on a data-driven approach.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.12
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• pp.1560-1570
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• 2007

The purpose of this study was to investigate the differences according to lifestyle in anthropometric measurement, dietary attitude, health-related behaviors and nutrient intake among the college students. The subjects were 994 nation-wide college students (male: 385, female: 609) and divided into 7 clusters (PEAO: passive economy/appearance-oriented type, NCPR: non-consumption/pursuit of relationship type, PTA: pursuit of traditional actuality type, PAT: pursuit of active health type, UO: utility-oriented type, POF: pursuit of open fashion type, PFR: pursuit of family relations type). A cross-sectional survey was conducted using a self administered questionnaire, and the data were collected via Internet or by mail. The nutrient intake data collected from food record were analyzed by the Computer Aided Nutritional Analysis Program. Data were analyzed by a SPSS 12.0 program. Average age of male and female college students were 23.7 years and 21.6 years, respectively. Most of the college students had poor eating habits. In particular, about 60% of the PEAO group has irregularity in meal time. The students in PAH and POF groups showed significantly higher consumption frequency of fruits, meat products and foods cooked with oil compared to the other groups. As for exercise, drinking and smoking, there were significant differences between PAH and the other groups. Asked for the reason for body weight control, 16.2% of NCPR group answered "for health", but 24.8% of PEAO group and 26.3% of POF group answered "for appearance". Calorie, vitamin A, vitamin $B_2$, calcium and iron intakes of all the groups were lower than the Korean DRIs. Female students in PTA group showed significantly lower vitamin $B_1$ and niacin intakes compared to the PFR group. Therefore, these results provide nation-wide information on health-related behaviors and nutrient intake according to lifestyles among Korean college students.

• Proceedings of the ESK Conference
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• 1995.04a
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• pp.84-93
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• 1995

우리 나라도 최근들어 소득수준 향상, 건강의식의 고조, 평균수명의 연장등으로 고령화 사회의 진전추세가 가속화되고 있다. 한국보건사회연구원(1987)의 조사에 의 하면 국내 인구의 고령화 속도는 급속히 빨라져 65세 이상 노인 인구의 비가 전체 인구의 5.5%를 차지하고 있으며, 2,000년에는 노인이 전체인구의 7%, 2,025년에는 14%에 달할 것이라고 하며, 이 속도는 프랑스 보다 4.6배, 미국에 비해서는 3배나 빠르다 한다. 인구 구성비에서 65세 이상의 노인 인구가 7%를 넘는 사회를 고령화 사회, 14%를 넘으면 고령사회로 정의를 하고 있는 유엔의 규정을 감안한다면 우리 나라도 앞으로 수년내에 본격 고령화 사회로 접어들게 될 것이다. 본 연구에서는 인간의 행동이 머리의 판단과 수족의 동작으로 이루어 지므로 동작 및 판단속도의 연령대별, 성별 수행성취도 차이를 비교분석하여 그 특성을 고찰하고 그 결과로 고령 자의 고용에 필요한 근로능력의 평가, 고령자의 근로적응을 위한 직무나 작업장의 설계, 더 나아가서는 노인의 복지향상을 위한 복지시설의 설계시 이용할 수 있는 기초자료를 제공하고자 한다.

• Journal of Radiation Protection and Research
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• v.20 no.3
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• pp.187-200
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• 1995

This paper reviews studies on potential health effects of electric and magnetic fields at extremely low frequencies(ELF). Recent studies focus on the epidemiological investigation of cancer, reproductive outcome and neurobehavioral effects due to residential and occupational exposure to ELF. Laboratory experiments are also carried out to find the possible mechanism of biological effects of ELF. Firm conclusion regarding whether ELF cause cancer are not yet conclusive but suggestive and other health effects of exposure to ELF have also been suggested but the evidence is even weaker than that related to cancer.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.8
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• pp.303-311
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• 2018

This study was conducted to investigate the effects of oral health awareness and oral health behavior on cardiocerebrovascular prevention behavior in a cardiocerebrovascular diseases risk group and provide basic data for a nursing intervention program for the group. Data were collected from 131 people in the risk group of cardiocerebrovascular diseases living in J Province in February and March of 2018. The obtained data were analyzed using descriptive statistics, t-tests, Pearson's correlation, and stepwise multiple regression analysis. The results revealed that preventive acts were positively correlated with subjective oral health state (r=0.261, p=0.003), importance of oral health (r=0.250, p=0.004), and practice of oral health (r=0.303, p<0.001). Moreover, acts to prevent cardiocerebrovascular disease were influenced by oral health (${\beta}=0.29$, p<0.001), age (${\beta}=0.27$, p=0.001), and subjective oral health state (${\beta}=0.24$, p=0.003). Specifically, scores of preventive acts for cardiocerebrovascular diseases increased with higher degree of oral health behavior, older age, and better subjective oral health state. These variables had an explanatory power of 19.3%. The results of this study imply a need to prepare measures to enhance the oral health level of the risk group of cardiocerebrovascular diseases and conduct ongoing follow-up studies of the perception, attitude, and behavior of individuals toward oral health, as well as the state of oral health.

• Journal of Nutrition and Health
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• v.44 no.6
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• pp.537-550
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• 2011

This study was conducted to identify behavioral characteristics of salty food intake according to saline sensitivity of adults living in a rural area. Anthropometry and blood pressure were measured and salt intake-related dietary behavior was surveyed by questionnaires through interviews with 402 subjects aged ${\geq}$ 40 years in Chungcheongbuk-Do, Korea. The percentages of overweight and obese among the subjects were 37.8% and 3.8% respectively. Mean blood pressure of the subjects was in the normal range, but the distribution of subjects who were normotensive, high normal, and hypertensive was 48.7%, 17.7%, and 33.6% respectively. Approximately 27% of all subjects habitually consumed salty food, which was the smallest group, followed by 38.1% normal and 35.1% not-salty food. However, 34.6% of the eldest group of ${\geq}$ 65 years consumed salty food. The saline insensitive group showed a higher percentage of irregular meals, overeating, speed-eating, an unbalanced diet, a preference for fried food, and habitual intake of salty foods. These subjects recognized the risk for eating salty food, but they lacked the will to reduce their salty food intake. Compared to spouses and family members, experts such as doctors, nurses, and dieticians were the most influential for reducing the salty food intake of subjects. Saline sensitive group had relatively better control over salty food intake at every meal, eating out, and even when eating salty food that the spouse preferred. The saline sensitive group ate more frequently vegetables and fruits, whereas the saline insensitive group ate more frequently hot spicy foods. In conclusion, the results suggest that it is necessary to establish a social atmosphere toward reducing salt intake at the level of the government and food industry and to set action plans to be available for nutrition education programs to reduce salt intake nationwide.

• Journal of agricultural medicine and community health
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• v.33 no.1
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• pp.11-26
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• 2008

Objectives: We evaluated the level of psychosocial stresses and fatigue symptoms among clerical public officers and its related factors.Methods: The self-administered questionaires were performed, during the period between Dec. 5th, 2005 Metropolitan City. The survey items included subjects' socio-demographic and job-related characteristics, health-related behavior, degree of job demand, job autonomy, social support in work, type A behavior pattern, locus of control, sense of self-esteem, psychosocial distress and degree of fatigue.

• Women's Health Nursing
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• v.4 no.3
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• pp.322-331
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• 1998

The postpartum is a period of transition to motherhood where a childless woman transforms into a woman with children. Parents, especially mothers must perform an essential role of implementing instrumental and emotional care behaviors on part of the helpless, dependent, and immature infant. First-time mothers, however, suddenly face the responsibility of round the clock duty without neither parenting training during pregnancy, nor a time to gradually adapt to growing responsibilities after birth, with confusion and frustration as a result. Thus, after providing first-time mothers with childcare education as maternal role preparation, this study will try to examine its effects on childcare behaviors and confidence in maternal role during the early postpartum period. This quasi-experimental study using a nonequivalent control group non-synchronized design, was carried out from March 1995 to May 1996 to verify the effects of a childcare education program with first-time mothers who had vaginal delivery in Ewha University Hospital, Seoul, Korea, and collected data from 60 subjects who consented to the study. The education was given in the early postpartum period(48-72 hours after delivery) and to measure its effects, a posttest was done 4 weeks later with the results analyzed by SPSS shown in the following : 1. The childcare behavior score of the experimental group that had received the newborn care education was higher than the control group(t=3.5, P=.001). 2. The control group and the experimental group which had received the education showed no difference in degree of confidence in maternal role. 3. The higher the childcare behavior score, the higher the degree of confidence in maternal role was among the subjects(r=.56, P=.001). The preceding results are significant in that childcare practices can be promoted by providing child-care education to first-time mothers in the early postpartum period. Thus, this education can be used as a nursing intervention strategy in the early postpartum period.