• Korean Journal of Plant Resources
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• v.37 no.2
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• pp.120-129
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• 2024

Alcoholic liver disease (ALD) is a significant risk factor in the global disease burden. The stem bark of the Betulaceae plant Alnus japonica, which is indigenous to Korea, has been used as a popular folk medicine for hepatitis and cancer. However, the preventive effect of Alnus japonica leaf extracts on alcohol-related liver damage has not been investigated. The objective of this study was to investigate the hepatoprotective effects of the extracts of Alnus japonica leaf (AJL) against ethanol-induced liver damage in HepG2/2E1 cells. Treatment with AJL significantly prevented ethanol-induced cytotoxicity in HepG2/2E1 cells by reducing the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). This protective effect was likely associated with antioxidant potential of AJL, as evidenced by the attenuation of reactive oxygen species (ROS) and malondialdehyde (MDA) production and restoration of the depleted glutathione (GSH) levels in ethanol-induced HepG2/2E1 cells. Our findings suggest that FCC might be considered as a useful agent in the prevention of liver damage induced by oxidative stress by increasing the antioxidant defense mechanism.

• Journal of Digital Convergence
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• v.10 no.3
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• pp.207-218
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• 2012

The purpose of this study is to provide preliminary data for political measures to minimize the variations by understanding the regional variations and trends of hospital services for heart diseases, and analyzing the factors that could occur any variations. The various data collected from nation-wide inpatient services conducted separately by small region show that there have been some differences in income level, supply of medical resources, standardized rate of hospitalization by sex and age, health level in the residence, and the length of stay per head. Then it indicated that the number of special medical equipment per 10,000 people and the rate of vigorous physical activity have the highest influence over the regional variations in using hospital services. On the other hand, the number of sick-beds per 10,000 people, the number of special medical equipment, and the present smoking rate have significant degree of influence on the length of stay per head. Thus, it is imperative for the authorities to set aside health promoting policies and to distribute the medical resources equitably throughout the country and to enhance the accessibility of local residents to the health care services.

• Journal of Environmental Impact Assessment
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• v.27 no.2
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• pp.152-169
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• 2018

The purpose of this study was to analyze the effect of adjacentroads on the concentration of negative air ions in urban neighborhood park. The measured factors were negative air ion concentration, positive airion concentration, airtemperature,relative humidity, wind speed, green formation volume factor (GVZ) and distance from highway and general road. The mean negative air ion concentration was $206ea/cm^3$ and the positive air ion concentration was $416ea/cm^3$ in the influence zone of roads. On the other hand, the mean negative air ion was $339ea/cm^3$ and the positive air ion was $229ea/cm^3$ in the unaffected zone of roads, which are inner areas of the park. The difference of the negative air ion concentration according to the influence of the road was statistically significant. The negative air ion concentration model was presented by integrating the correlation analysis with the influence factors, and the explanatory power of the model was increased by adding the influence factor of the road.

• Journal of the Korean Institute of Landscape Architecture
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• v.42 no.3
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• pp.76-89
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• 2014

The functions of urban park including health related benefit and climate adaptation and mitigation are expanding. However, in-depth research and discourse on the equitable distribution of expanded park function has been limited so far. Following research suggests Green Welfare concept to reflect distributive equity and multifunctionality in the process of urban park policy development and execution. This study developed park welfare indices to analyze disparities of neighborhood urban park(NUP) distribution viewed from green welfare by literature review. The findings analyzed through the Correlation Analysis and Cluster Analysis by SPSS 18.0. The results of the study are as follows. First, green welfare is defined as "to receive equitable benefits and participate in the delivery process of green services which are promoting health and securing safety from climate change risks for every citizen by life cycle regardless of socioeconomic status". Second, NUP per person in Seoul indicate meaningful differences by socioeconomic and environmental status of Seoul administrative districts. Park welfare indices correlated to NUP per person were shown population density(negative), percentage of individuals $aged{\geq}65$(positive), percentage of self-reliance of local finance(positive), flood and air pollution vulnerability by climate change(negative). Third, the cluster analysis identifies three significant clusters that indicate differences of park welfare level. Thus, it was found that NUP in Seoul from a green welfare perspective was provided disproportionately. Future urban park policy in Seoul was required equitable distribution of multifunctionality of park beyond quantitative expansion, and priority consideration should be given to park service consumer.

• Environmental and Resource Economics Review
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• v.18 no.3
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• pp.393-430
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• 2009

This study uses a computable partial-equilibrium model of the U.S. energy industry to evaluate sulfur dioxide concentrations under two environmental policies. The policies, generator-level emission caps and tradable allowances, are selected to yield identical aggregate emissions. Regional concentrations are found to vary across the two policies significantly. These variations translate into different losses for individual states, and, nationwide, to differences of hundreds of millions of dollars in aggregate health damages. Emission caps outperform allowances by $452 million. Caps favor the southwestern, south-central and southeastern states, where they deliver $840 million lower damages than the other policies, while they deliver $390 million higher damages In northern and northeastern states.

• Child Health Nursing Research
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• v.23 no.3
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• pp.319-328
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• 2017

Purpose: This study was conducted to identify factors affecting health promotion behaviors of upper grade elementary students. Methods: A descriptive study was carried out with 282 fifth or sixth elementary school students from two cities, Korea. Data were collected using self-administrative questionnaires containing items on health knowledge, attitudes, subjective norms, perceived behavior control and health promotion behavior, and analyzed using descriptive statistics, t-test, ANOVA, Cronbach's ${\alpha}$, Pearson Correlation Coefficients, and multiple regression analysis with the SPSS/WIN 21.0 program. Results: There were significant positive correlations between health promotion behavior and health knowledge (r=.36, p<.001), attitudes (r=.41, p<.001), subjective norms (r=.36, p<.001), perceived behavior control (r=.49, p<.001). Perceived behavior control (${\beta}=.38$, p<.001), health knowledge (${\beta}=.26$, p<.001), perceived health status - good (${\beta}=.15$, p=.005) were significant factors affecting health promotion behavior and explained 31%(F=43.29, p<.001) of variance. Conclusion: Results indicate that level of health promotion behavior is appropriate and perceived behavior control is the most important factor for health promotion behavior among the predictors. These findings also suggest that it is necessary to promote perceived behavior control and health knowledge in developing health promotion intervention programs for these students, as well as a need to strengthen education on sex behavior and health, accident prevention and first aid.

• Korean Institute of Interior Design Journal
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• v.15 no.5 s.58
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• pp.298-305
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• 2006

The purpose of this study is to figure out the profiles of eco-friendly finishing materials and intoner products through content analysis on the advertisements of three domestic interior design magazines, which have been published for 4 years since 2002. The amount of advertisements has been continuously increasing due to the public concerns on well-being. Finishing material types absolutely took the greatest proportion (92.8%), while products such as furniture and household equipments were only 7.2% among the advertisements. Charcoal, natural jade, yellow soil and nano-silver were the frequently mentioned health-related components in the finishing material. Only 35.7% of the finishing materials hold certification on indoor air quality. Among the interior products, phytonchid in air cleaner was the only advertised component related to health. In conclusion, controlling pollutants of indoor air quality, such as HCHO, VOC, seems to be the big issue in both materials and products due to the concern of Sick Building Syndrome. However, more scientific and objective guidelines are necessary for consumers to live in healthy interior environment.

• Proceedings of the Korea Technology Innovation Society Conference
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• 2015.11a
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• pp.430-443
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• 2015

신약개발은 국민의 건강권과 직결되며 국가 차원의 제약산업 육성을 위해 매우 중요하다. 그동안 신약개발 분야와 관련하여 다양한 연구가 수행되었지만, 신약개발 분야의 국가연구개발사업에 대한 효율성 분석은 매우 부족한 실정이다. 특히 R&D 분야는 연구개발시차, 일출효과(spill-over effect) 등으로 인해 투입과 산출의 일정한 방향성과 등비율적인 증감을 가정하는 CCR 모형이 적합하지 않다. 또한 가변규모수익을 가정하는 BCC 모형도 여유분(slack)으로 인해 의사결정단위간의 명확한 우선순위 도출이 어려운 한계점이 있다. 최근에는 R&D 분야의 특수성을 고려해서 자료포락분석 모형 중 RAM(Range Adjusted Measure) 모형을 활용한 분석방법이 제시되고 있다. RAM 모형은 가변규모수익 가정 하에 투입지향이나 산출지향처럼 방향성에 대한 사전적인 가정 없이 비효율성을 최대한 제거하는 방향으로 효율성을 측정하므로 R&D 분야의 효율성 분석에 적합하다. 특히 RAM 모형은 매우 강건한 단조성을 인해 의사결정단위 간 명확한 순위 구분도 용이하다. 따라서 본 연구에서는 자료포락분석 모형 중 RAM 모형과 토빗 회귀분석이 결합된 2단계 접근법을 활용해서 범부처전기신약개발사업을 중심으로 신약개발 분야의 국가연구개발사업들에 대한 효율성을 분석하고 주요 시사점들을 논의하였다.

• Korean Parent-Child Health Journal
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• v.18 no.1
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• pp.28-38
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• 2015

Purpose: This study was conducted to identify the role and role burden of caregivers with hospitalized children. Methods: The participants included 149 main caregivers from two pediatric hospitals whose children have been hospitalized for at least 2 days at children's hospital. The data were collected from August 1 to september 30, 2013 using self-report questionnaires of checklist type for caregivers' role and Likert scale for role burden. Results: Role for hospitalized children showed that personal hygiene was the highest, and consultation with nurses and doctors was the lowest in total frequency per day. Of the role for the caregivers themselves and family, personal hygiene was the highest, and home management was the lowest. The degree of role burden perceived by hospitalized children's caregivers was the slightly high. Of the categories, emotional burden was the highest and dependent burden was the lowest. There were differences by caregivers' age, children's age, and children's health status. Conclusion: The caregivers performed various roles, especially more frequently on personal hygiene and nutrition for their hospitalized children and themselves and family, and had slightly high role burden. These results may contribute to develop nursing interventions that can help adapt on hospitalization of children and their caregivers.

• Korean Parent-Child Health Journal
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• v.12 no.2
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• pp.177-187
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• 2009

Purpose: Mothers are primary care taker for hospitalized children and they have an important role for the management of children's pain. This study was purposed to provide basic data needed in constructing the educational contents about pain management for the hospitalized children. Method: The research subjects were 165 mothers of children hospitalized at a general hospital in Busan. The questionnaire were composed of knowledge of, using attitude toward and education demand on analgesics. The data were collected from August 1 to September 30, 2009. Data were analyzed by SPSS 17.0 program. Results: The overall mean score of correct answers on knowledge about analgesics was 26.9% and using attitude toward analgesics was $25.55{\pm}4.03$. And demand of education was $3.98{\pm}0.66$. Conclusions: The level of mothers' knowledge about analgesics was very low and using attitude toward analgesics was passive. The hospitalized children's mothers need more knowledge and liberalness attitude toward analgesics. And various and sufficient educational program about analgesics and pain management for hospitalized children's mothers can be contribute to improve the quality of life of them.