• Proceedings of the KOR-BRONCHOESO Conference
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• 1982.05a
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• pp.16.2-16
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• 1982

The palatine tonsils which are located in entrance of digestive and upper respiratory tracts are the most important organ in anatomical and functional structures of the pharyngeal lymphatic tissues. As for function of the tonsil, there have been many suspected theories that were included hematopoietic, hormonal, digestive function and production of vitamin, entry of bacteria with other antigenous materials and defence mechanism of which has taken charge by Virchow in 1860 in past. But among these theories, in recently, defence mechanism of the tonsil was strongly accepted immunologically. For the purpose of elucidating immune response of the tonsil, the author observed serum immunoglobulin levels, peripheral total lymphocyte counts and populations of T, B and Null lymphocytes before and after tonsillectomy in 30 cases of patients with chronic tonsillitis and 29 cases of healthy controls. The results obtained were as follows; 1) Serum Ig M level was significantly higher in patient group than in control group but was not significantly different preoperative from postoperative patient group. 2) Population of T-lymphocyte more significantly decreased in patient group than in control group but it was not significantly different preoperative from postoperative patient group. 3) Population of B-lymphocyte more significiantly increased in patient group than in control group but it was not significantly different preoperative from postoperative patient group. On the basis of these results, it may be suggested that tonsil play partially a role in the immune response of human.

• Journal of Veterinary Clinics
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• v.24 no.3
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• pp.325-330
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• 2007

This study was to determine whether canine model which produce acute permanent joint instability in short period without postoperative exercise have a degenerative changes and also evaluated its suitability as an appropriate animal OA models. Ten skeletally mature beagle dogs underwent a unilateral surgical transection of the cranial cruciate ligament and, the medial collateral ligament as well as a medial meniscectomy. The contra-lateral joint was used as control. After 12 weeks, After 12 weeks, the amount of joint damage, inflammation and biochemical change of synovial fluid was evaluated. Histological analysis showed chondrocyte clone formation, hypertrophy of the cartilage and moderate loss of proteoglycans in the experimental joints compared to control joints. In addition, the synovial inflammation in the experimental joints was observed. Biochemical analysis of SF showed significantly increased MMP (matrix metalloproteinase) -2 and -9 in experimental joints compared to control joints. This canine OA model shows the characteristics of degenerative joint disease, and may have a advantages of reducing the time and cost because postoperative exercise is not needed in this OA model.

• Korean Journal of Plant Tissue Culture
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• v.26 no.1
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• pp.1-6
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• 1999

In order to obtain plantlet derived by anthers, the anthers of Lilium asiatic hybrid 'Gran Paradiso' were cultured on Murashige and Skoog's medium supplemented with various combinations of auxin and cytokinin. The most suitable pollen stage of anther culture for the callus induction was 3 days before anthesis at the early to late binucleate stage. Organogenic calli were induced on MS medium supplemented with 5.0 mg/L 2,4-D alone and the combination of 1.0 mg/L 2,4-D and 1.0 mg/L kinetin, however, the combination of NAA and BA was more effective than that of 2,4-D and kinetin on plant regeneration through organogenesis. Shoots were formed from the induced callus on the medium with 0.5 mg/L NAA and 1.0 mg/L BA after 180 days of culture. Multiple shoots with 3-4 leaves, roots, and bulblets were formed on the medium with the combination of 2.0 mg/L NAA and 2.0 mg/L BA after 250 days of culture. The chromosome from root tip of the regenerated plantlet showed the diploid (2n=2x=24). Diploid plants were transferred to the pots and all plants were flowered in two years.

• Korean Journal of Plant Tissue Culture
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• v.28 no.6
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• pp.347-351
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• 2001

Panax ginseng C.A. Meyer is a well-known Korean traditional medicine. Until now, even though major research of ginseng has been focused on the pharmacological effect, clinical application and chemical analysis of extracted secondary metabolite for several years, the physiology and gene functions of ginseng were not well known. In this research, we have developed the protein extraction methods of ginseng root and hairy root for proteome analysis in order to elucidate the gene(s) function of ginseng. Using the liquid nitrogen (equation omitted) TCA method as protein extraction method, about 660 protein spots were detected on the 2-DE gel of hairy root. Additionally, comparative analysis result of 2-DEs of ginseng root (equation omitted) hairy root suggested that proteomes of same organism could be changeable according to the culture condition, growth stages and other stimulus.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.13 no.4
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• pp.129-138
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• 2003

Role-Based Access Control(RBAC) model is becoming a promising model for enterprise environments with various organization structures. In terms of role hierarchy, each senior role inherits all the permissions of its junior roles in the role hierarchy, and a user who is a member of senior role is authorized to carry out the inherited permissions as well as his/her own ones. But there is a possibility for senior role members to abuse permissions. Since senior role members need not have all the authority of junior roles in the real world, enterprise environments require a restricted inheritance rather than a unconditional or blocked inheritance. In this paper, we propose a new role-based delegation model using the role hierarchy model with restricted inheritance functionality, in which security administrator can easily control permission inheritance behavior using sub-roles. Also, we describe how role-based user-to-user, role-to-role delegations are accomplished in the model and the characteristics of the proposed role-based delegation model.

• Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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• 2000.04a
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• pp.6-7
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• 2000

개발도상국의 급격한 인구 증가에 의해 세계 60억 이라는 인구도 2050년을 맞아 약 100억에 도달할 것이라고 일컬어진다. 이로 인한 장래의 식량 위기에 대비하여 벼, 밀, 옥수수 등의 증산, 품종 개발도 물론 필요하지만 선진국을 중심으로 시장성 높은 작물의 소비가 우선되어지는 상황에 맞추어 세계적으로 주식이 될 수 있는 새로운 곡류의 확보와 생산체제도 중요한 문제이다. 한편으로 생활의 향상에 따른 식물의 다양화와 건강지향의 관점으로 본 다 품목 소량형의 식생활을 하는 것이 식물성 allergy의 방지 측면으로서의 곡류 특히 잡곡류의 유효 이용이 부각되어진다. 이들 중 amarans, quinoa는 벼과 식물에 비교해서 광합성능이 좋은 C4식물로서 생장이 빠르고 동시에 비타민, 무기질, 지질이 풍부하고 구성 단백질 중에 필수 아미노산을 많이 함유하여 아미노산 등급도 높고 특히 영양 발란스도 우수하다. 또 cholesterol 저하작용, 식물섬유에 의한 대장암의 억제 작용 등이 잘 알려져 있다. 그리l고 quinoa에 대해서는 아메리카 항공우주국(NASA)에서 CELSS(Controlled Ecological Life Support System; 장기간 우주특무비행의 승선원을 위한 공기중의 이산화탄소를 제거하고 식량·산소·물을 만들어 내기 위해 식물을 이용하는 방법)에 적합한 작물 후보로써 선택되어 신규 식품소재로써 주목받고 있다. 이상과 같은 견지로부터 amarans, quinoa를 일상식화되고 있는 빵에 이용하기 위해 제빵성 및 혼합중의 반죽의 모든 성질에 대해서 검토했다. amarans는 초과의 Amaranthus에 속하고 주요 생산국은 아메리카, 멕시코, 페루등이지만 일본에서는 주로 A.hypochondriacus가 수입되어 이용 되어지고 있다.amarans의 가루는 단독으로는 점탄성 있는 반죽을 형성하지 않기 때문에 밀가루에 일부를 대용한 wheat flour dough를 사용하고 가정용 제빵기로 구워 최종 단계에까지의 제빵성 결과를 산출했다. amarans folur 5%의 대체에는 빵의 비용적이 비교적 증대했지만 그 이상 amarans flour을 대처하면 확연히 비용적은 감소했다. amarans flour 10% 대체에 hemicellulase 1250U 이상을 첨가하면 비용적은 눈에 띄게 증대했다. farinograph에 있어서 반죽의 안정성은 amarans flour 10% 대용에 현저히 감소했다. 반죽의 점탄성(아축응력, 탄성률, 점성계수)는 amarans flour 10%를 대용한 것이 무첨가한 것보다 많이 단단해졌음을 알 수 있었다. 혼합중의 반죽의 조사형 전자현미경 관찰로 amarans flour로 대체한 gluten이 단단해졌음을 알수 있었다. 유화제 stearly 칼슘, 혹은 hemicellulase를 amarans 10% 대체한 밀가루에 첨가하면 확연히 비용적을 증대시킬 수 있다는 사실을 알 수 있었다. quinoa는 명아주과 Chenopodium에 속하고 페루, 볼리비아 등의 고산지에서 재배 되어지는 것을 시료로 사용하였다. quinoa 분말은 중량의 5-20%을 quinoa를 대체하고 더욱이 분말중량에 대하여 0-200ppm의 lipase를 lipid(밀가루의 2-3배)에 대하여 품질개량제로서 이용했다. 그 결과 quinoa 대량 7.5%에서 비용적, gas cell이 가장 긍정적 결과를 산출했고 반죽의 조직구조가 강화되었다. 또 quinoa 대체에 의해 전분-지질 복합제의 흡열량이 증대된 것으로부터 전분-지질복합제의 형성 촉진이 시사되었다.이것으로 인하여 호화억제에 의한 노화 방지효과가 기대되었지만 실제로 빵의 노화는 현저히 진행되었다. 이것은 quinua 대체량 증가에 따른 반죽의 안정성이 저하되어 버린 것으로 생각되어진다. 더욱이 lipase를 첨가하면 반죽이 분화하는 경향이 보여졌지만 첨가량 75ppm에 있어서 상당히 비용적의 증대가 보였다. 이것은 lipase의 가수분해에 의해 생긴 monogliceride에 의한 유화각 일어나서 보존성이 개선되어진 것으로 quinoa를 보다 많이 빨에 이용하기 위해서는 lipaserk 품질개량제로서 유효하다는 것을 알 수 있었다. 또 lipase는 quinoa의 대체량이 비교적 많은 10-20%의 섭취가 곧 allergy 질환 문제의 개선책이 되는 것은 물론 amarans, quinoa에는 lysine, 함황아미노산이 많고 지질중의 지방산조성도 좋고 무기질도 많이 함유되어 있다. 이와같이 우리들 개인의 건강에 대한 배려도 있고 amarans, quinoa등의 식품재료를 적극적으로 사용할 수 있도록 유념해 두었으면 하는 바램이다.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.10 no.4
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• pp.305-313
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• 2016

Movements of the lower limb are important for normal walking and smooth oscillation of the center of gravity. The ankle rotations such as dorsi-flexion, plantar-flexion, inversion and eversion allows the foot to accommodate to ground during level ground walking. Current below knee (B/K) prostheses are used for replacing amputated ankle, and make it possible for amputees to walk again. However, most of amputees with B/K prostheses often experience a loss of terrain adaptability as well as stability because of limited ankle rotation. This study is focused on the development of multi-rotational prosthetic foot for lower limb amputee. Our prosthesis is possible for amputees to easily walk in level ground by rotating ankle joint in sagittal plane and adapt to the abnormal terrain with ankle rotation in coronal plane. The resistance of ankle joint in the direction of dorsi/plantar-flexion can be manually regulated by hydraulic damper with controllable nozzle. Furthermore, double layered rubber induce the prosthesis adapt to irregular ground by tilting itself in direction of eversion and inversion. The experimental results highlights the potential that our prosthesis induce a normal gait for below knee amputee.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.14 no.2
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• pp.47-59
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• 2019

Various studies have been carried out on the subject of entrepreneurship, which is required to create new businesses and organizations during the early process of startups based on innovative technologies and ideas. At the same time, the concept of organizational entrepreneurial orientation, which explains how to manage enterprises in the process of pioneering new products and markets, is drawing more and more attention for the purpose of continuously creating and maintaining a competitive edge of startups. This study focused on the relationship between entrepreneurial orientation and startup performance and the role of technological orientation and social capital. An empirical research was conducted on 144 different startup companies residing in startup supporting institutions. To evaluate the suitability of the research model, a PLS-based structural equation model was used. The research results are as follows: First, the entrepreneurial orientation of startups was found to have a positive effect on startup performance. Second, it was shown that entrepreneurial orientation had a positive effect on all three dimensions of social capital and technological orientation. Third, it has been shown that technological orientation and the cognitive dimension of social capital mediates the relationship between entrepreneurial orientation and startup performance. Through this, it was confirmed that entrepreneurial orientation directly affects startup performance, and it even influences the growth of startups by increasing technological superiority and social capital which is inherent in the network. Also, the research identified the need for additional research on the relationship between the strengthening of technological orientation and strategical orientation in startups. This study is expected to expand the discussion about social capital in the field of startup related research by affirming the role and importance of the cognitive system embedded in the network as well as the connectivity of networks, which has been already emphasized in previous startup related studies. Finally, the results of this study were reflected to present new practical implications.

• The Journal of the Korea Contents Association
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• v.12 no.6
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• pp.380-389
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• 2012

In this study, Systematic review and meta-analysis using the correlation coefficients was carried out to integrate precedent studies on factors affecting domestic occupational therapists' job stress. It aims at providing basic information resources of preventing and reducing stress of occupational therapists and effective counter-measurement to improve quality of occupational therapy and to establish efficient human resource management policy. Systematic review and meta-analysis were performed on eight thesis proven relevant to selection criteria in order to figure out correlation coefficients value by total, and factors correlation coefficients value. Also homogeneity test and publication bias test was performed too. The total correlation coefficients value of occupational therapists was .30 which was statistically significant. As to job stress factors, the organization related factor showed the highest correlation of coefficiency, followed by factors other than the organization related, physical environment, job related factor and personal factor. This research result can be used as a reference to prevent and reduce job stress of occupational therapists and to develop an effective measurement scheme.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.213-213
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• 2016

수문조사기기의 검정은 수문조사에 활용할 기기를 일관되고 표준화된 기준으로 검사하여 수문조사에 적합한 기기인지 확인하는 것이다. 이러한 검정은 국가수문자료의 신뢰도를 높이고 유지하는 기본적이고 중요한 업무이다. 검정대상기기는 강수량측정기기, 유속측정기기, 수위측정기기, 부유사측정기기, 토양수분측정기기, 증발산량측정기기로 총 6가지이며, 2009년부터 국토교통부 위탁사업으로 한국건설기술연구원(유량조사사업단)에서 수행하고 있다. 특히 유량조사사업단에서는 유속측정기기를 제외한 나머지 5개 수문조사기기에 대해 검정을 수행하고 있다. 연도별로 2009년부터 2015년까지 98대, 334대, 572대, 539대, 359대, 682대, 690대로 총 3,274대를 검정하였고, 관측기종별로 강수량 1,579대, 수위 1,589대 부유사 23대, 토양수분 33대, 증발산량 50대이다. 신청기관별로는 국토교통부(홍수통제소) 1,847대, 환경부(국립환경과학원) 4대, 한국건설기술연구원(유량조사사업단 포함) 81대, K-water 338대, 한국수력원자력(주) 91대, 일반업체 913대에 대한 검정을 실시하였다. 검정을 실시한 강수량측정기기 1,579대 중 보정없이 합격된 기기는 1,495대, 허용오차기준에 미달되어 보정 실시 후 합격한 기기는 76대이며, 불합격 처리된 기기는 8대이다. 수위측정기기는 합격이 1,586대, 기준에 미달되어 불합격된 기기가 2대로 나타났다. 강수량측정기기의 각 연도대비 통계분석 결과 보정률은 2009년 97대 중 8대(8.2%), 2010년 194대 중 3대(1.5%), 2011년 180대 중 24대(13.3%), 2012년 175대 중 17대(9.7%), 2013년 165대 중 15대(9.1%), 2014년 547대 중 8대(1.5%), 2015년 221대 중 9대(4.1%)로 다소 낮은 수치로 나타났다. 이처럼 보정률이 낮게 나타난 이유는 관할기관의 검정을 위한 유지관리 및 사업자의 사전검사 등을 통해 감소한 것으로 판단되며, 이와 같은 결과는 수문자료의 품질 및 신뢰도 향상으로 이어졌다. 그러나 여전히 선진국에 비해 수문조사기기 검정의 중요성에 대한 인프라 구축이 미흡한 실정이다. 수문조사기기 검정의 선진국이라 할 수 있는 미국의 경우 USGS에서 HIF(Hydrogical Istrumentation Facility)라는 별도 조직을 운영하여 관측기기의 렌탈, 수리, 교정 및 검정, 개발, 교육 등 이러한 작업을 일괄 수행하고 있고 조직 내 자체 시설로 수중펌프 시험소, 자연과 유사한 환경에서 테스트 하는 장소, 대형온도챔버 등을 갖추고 있으며, 이러한 시설을 이용하여 기기의 교정 및 검정, 연구 등을 현장과 비슷한 환경에서 다양한 실험을 통해 검정방법을 비교, 분석하는 것을 볼 수 있다. 현재 우리나라의 수문조사기기는 다양한 방법으로 현장에 설치되어 검정방법의 다양성이 요구된다. 향후 우리나라도 HIF와 같이 다양하고 선진화된 시설과 기술을 개선하고 다각적인 시험 과정을 통해 수준 높은 검정방법체계를 갖추려는 노력이 필요하다.