• Archives of design research
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• v.14 no.1
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• pp.119-134
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• 2001

It can be said that Italian designs are unrestrained, aesthetic and art for arts sake, and they come to stylize their character based on geographical features, racial traits and culture. The Italian architects work for the reconstruction of their devastated country and spare no pains to produce competitive goods on international markets since the second wend war. In spite of a inherent scarcity of resources, Italian furniture is the product of mixture of aesthetic material and new material with creative gifts. A lot of companies succeed in finding and training capable designers and devote themselves to modem furniture industry. As a result, Italy becomes one of the worlds most eminent furniture industrial countries now. And the fame is owed to Italy's national awareness of the importance of the matter and endeavor without sparing systematic support. This research is to find out which factors have an influence on the progress of furniture design in Italy and to analyze how these factors build up formative arts combining with historical background in Italy. Moreover, this research suggests how to make contributions to the cause of furniture design growth when considering our geographical features, racial characteristics, culture and industrial circumstances, by analyzing the process of development and strategy in Italian design industry.

• Journal of Science Education
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• v.38 no.3
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• pp.657-669
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• 2014

The purpose of this research is to investigate the effect of students' storytelling on the science learning motivation and science related attitude in elementary science class. We had developed storytelling materials for 11 class hours on the 'Heat transfer and our life' unit based on the analysis of the 4th grade-science curriculum. The research sample was 22 4th graders who were belonged to one of the classes at an elementary school in Gwangju. The test of students' science learning motivation and science related attitude were administered before and after the storytelling treatment, and the difference was checked by the paired t-test using SPSS program. Students' perceptions on the storytelling were also investigated. The conclusions of this research are as follows. First, the students' storytelling tend to have somewhat positive influence on learning motivation. The each mean of post-test in the domain of attention, confidence and satisfaction was significantly higher than that of pre-test. Second, students' storytelling have a positive influence on scientific attitude. Although the means of post-test were higher than those of pre-test in both science subject attitude and scientific attitude domain, a statistically significant difference was found only in the scientific attitude domain. For future researches, the development of more story-materials or strategies for effective storytelling is needed.

• Journal of Korean Society of Transportation
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• v.25 no.1 s.94
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• pp.23-35
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• 2007

Freeway diverging areas are very vulnerable to traffic accidents due to abrupt vehicle speed changes and geometric changes. Therefore, in designing diverging areas, much attention should be Paid to safety The Present design criteria about freeway diverging areas regulate transition sections for lane changes, deceleration lanes, transition corves for direction changes. and other similar items. However, the design criteria were often violated in implementation because of ambiguities in the criteria. This study aims at clarifying and improving the present design criteria for freeway diverging areas. For this, field survey data and traffic accident data for diverging areas were analyzed.

• Toxicological Research
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• v.23 no.3
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• pp.231-238
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• 2007

Evaluation of potentials of chemicals to alter expression of genes that are involved in carcinogenesis may serve useful tools in toxicological research. In this investigation, we developed reporter cell lines that expressed luciferase in response to transactivation of hypoxia inducible factor-1, P53 tumor suppressor and Nur77 of which roles have been well established in cancer development and progression. Whereas these reporter cell lines displayed low constitutive backgrounds, the reporter activities were significantly enhanced in response to $desferriosamine/CoCl_2$, adriamycin or 6-mercaptopurine, which are hypoxia mimicking chemicals, P53 activator or Nur77 inducer, respectively. The activation of the reporter was time- and dose-dependent. Known tumor initiators and promoters, such as phorbol 12-myristate 13-acetate and phorbol 12, 13-dicaprinate induced the reporter activity at as low as 10nM in these stable cell lines. Further, known anti-tumor promoters, such as ascorbic acid and ${\beta}-carotene$ repressed the reporter activities. These results indicate that our stable reporter cell lines could serve as a useful system for rapid assessment of carcinogenicity of toxic chemicals.

• Korean Journal of Food Science and Technology
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• v.50 no.2
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• pp.209-215
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• 2018

To evaluate the radical scavenging activity of phenolic-rich fractions of Gardenia jasminoides, we first measured the levels of total polyphenols in hexane, ethyl acetate, and butanol fractions from the extract of G. jasminoides. The ethyl acetate fraction of G. jasminoides extract (GJ-EA) showed high level of phenolics, potent reducing power, and 2,2-diphenyl-1-picrylhydrazyl/2,2'-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid radical scavenging effect. In addition, GJ-EA inhibited the overproduction of nitric oxide in lipopolysaccharide-activated BV-2 microglia. Furthermore, we found that GJ-EA suppressed $H_2O_2$-induced PANC-1 pancreatic cancer cell proliferation in a concentration-dependent manner and also reduced their migratory ability. These results suggest that GJ-EA may be a good source for functional foods with antioxidant and chemo-preventive activities.

• Applied Chemistry for Engineering
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• v.23 no.5
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• pp.496-500
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• 2012

Arthrospira platensis (A. platensis) is an economically important filamentous microalgae. The isolation of mutants by chemical or physical mutagen is a clue for the strain improvement. In this study, effects of ultraviolet-B (UV-B) radiation on A. platensis were investigated. Cells (or microalgae) were exposed to UV-B (15 Watt, 254 nm) for 1, 3, 5, and 10 min, and resulting mutants were designated UM1, UM3, UM5, and UM10, respectively. Especially, the lipid content of UM5 mutant was considerably increased by 8~11 fold compared to that of wild types. Moreover, the carotenoid content and antioxidant enzyme (peroxidase and superoxide dismutase) activity were increased. It was shown that UV-induced mutants can accumulate bioactive compounds, which will be useful for the industrial production of valuable products.

• Applied Biological Chemistry
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• v.44 no.1
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• pp.1-6
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• 2001

To elucidate the apoptosis mechanism of Trichoplusia ni cell, fundamental studies for apoptosis induction and suppression were performed. Hygromycin B, a known inducer of apoptosis, started the inhibition of T. ni cell growth at $200\;{\mu}/ml$ concentration. Furthermore, at $400\;{\mu}/ml$ concentration, DNA fragmentation was detected on day 2 of incubation. Although both dexamethasone and sodium butyrate inhibited T. ni cell growth, DNA fragmentation was not detected by both treatments. Also, when apoptosis induced T. ni cells with $200\;{\mu}/ml$ hygromycin B were treated with caspase inhibitor (Ac-DEVD-CHO), the apoptotsis was suppressed by 36%. In addition, N-acetylcysteine, another apoptosis repressor, also inhibited the apoptosis of T. ni cells. In order to express the anti-apoptosis gene (bcl-2), T. ni cells were transiently transformed with bcl-2 and its expression was confirmed by western blot analysis. These results showed the potential of developing new insect cell lines with suppressed apoptosis.

• Journal of Engineering Education Research
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• v.13 no.3
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• pp.68-77
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• 2010

This paper was designed to identify influencing factors and to develop indices for measuring information and communication technology related ethics behaviors of college students majoring in information and communication engineering. Data collected from 288 students surveyed in Busan and Kyungnam area were used and the average of information and communication engineering ethics were below the mid-points meaning 'fairly ethical'. 'Passively violating behavior' showed the highest value (2.77 out of 5) while 'rudeness and insulting behavior' showed the lowest (1.65 out of 5). Second, variables of gender, age, religion, idealism, and relativism were revealed to be meaningful ones. Results can help educators understand the influencing factors in information and communication technology related ethics behaviors of college students as well as develop topics in educating engineering ethics.

• The Journal of the Korea Contents Association
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• v.13 no.10
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• pp.9-18
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• 2013

In this paper, we analyzed the effects of game-based visual feedback training on postural balance control in young adults and older adults. We provided postural balance training by 23 young adults and 14 older adults and for four weeks in fifth minute a day and three days a week using IBalance(Cybermedic Inc., Korea). We evaluated the ability of postural balance using balance SD(Biodex, medicalscience Inc., USA) for the validation of game contents based on visual feedback training program. The results showed that postural stability and limits of stability of young adults and older adults were improved significantly before and after the training(p<0.05). Thus, the games of postural balance encouraged anterior, posterior, medial, lateral and multidirectional weight shifting regarding postural balance. Our study indicates that postural balance training of visual feedback based game could be adapted for improving postural balance. Moreover, we could develope of game contents for individuals and various ages for effective application of this game-based visual feedback training.

• Proceedings of the Materials Research Society of Korea Conference
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• 2012.05a
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• pp.57.1-57.1
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• 2012

금속을 용해 응고시킬 때 생성되는 소위, 주조 결함이나 소결금속 내의 기공은 재료의 성능이나 강도를 현저하게 낮추는 결함으로서 예전부터 기피되어 왔다. 또한, 재료공정에 있어서도 여하의 기공이나 기포가 없는 치밀한 고강도 및 고기능성 재료를 개발하는 것에 최대한의 주의와 관심을 기울여 왔다. 반면에 자연계의 천연물이나 인공물을 둘러보면 그 대부분이 다공질임을 쉽게 눈치챌 수 있다. 예를 들어 목재, 지엽 등의 생물을 시작해서 콘크리트 등의 인공물, 우리 체내의 뼈도 전형적인 다공질구조로 구성되어 있다. 이러한 구조로부터 재료의 재질제어 이외에 구조제어라는 새로운 어프로치를 고려할 수 있고, 최근 들어, 금속재료에 있어서도 이러한 다공질 구조에 관한 연구가 활성화되어 충격흡수재, 생체재료, 베어링재료 등의 다양한 응용이 전개되고 있다. 원주상의 방향성 기공을 갖는 로터스 금속의 제조 원리는 용융금속의 높은 가스용해도와 고체금속의 낮은 가스고용도의 차이를 이용하여 응고할 때 고용되지 않는 가스원자가 기포를 형성시키는 것이다. 수소용해도는 모든 금속에 있어서 온도상승에 따라 증가하지만 융점에 있어서 용해도의 불연속적 증가를 나타내며 응고할 때 고액계면에서 다량의 가스를 방출하고 기공 생성을 야기한다. 특히, 고 액상에 있어서 수소용해도 차가 큰 마그네슘, 니켈, 철, 동 등은 기포를 생성하기 쉽다. 또한 기공의 배열구조를 제어하기 위해 일방향응고법를 이용하여 기공에 방향성을 부여한다. 외관상 기공구조가 연근뿌리를 닮은 것으로 부터 로터스 금속이라는 명칭이 널리 알려져 있다. 이와 같은 제조방법에 의해 로터스 금속은 기공 방향, 기공크기, 기공률을 자유롭게 제어할 수 있고 우수한 기계적 성질이 기존의 발포금속, 소결금속과 전혀 다른 특성을 가지고 있다. 이러한 기공구조는 용해온도, 응고속도, 분위기 가스압, 불활성가스와의 혼합체적비 등의 제어를 통해서 조절할 수 있다. 이와 같이 제조한 방향성 다공질금속은 BT (인플란트, 생체적합성, 저탄성, 경량), ST (초음속기엔진부품, 경량), IT (고성능수냉모듈), ET(고온촉매, 필터)의 분야로의 응용을 기대한다.